Homo sapiens
The CIMH-NP-3 cell line was generated from induced pluripotent stem cells, which were generated from human fibroblasts by Sendai Virus reprogramming. Fibroblasts were obtained at the University of Bonn, Germany in March 2008. Reprogramming occurred at the Central Institute of Mental Health in Mannheim, Germany in February 2018. CIMH-NP-3 (stable neural progenitors) were generated in Mannheim in May 2018. Lentiviral transduction occurred in Mannheim, Germany, in May 2019 (to obtain PHP and WT Tau cell lines). The subject was a healthy 33-year-old male volunteer who gave written informed consent. All experiments are in line with the Helsinki Declaration.
isolate
GL-2025
age
33 yo
biomaterial_provider
Philipp Koch laboratory at Zentralinstitut fr Seelische Gesundheit, Mannheim, Germany
collection_date
2008-03
geo_loc_name
Germany: Mannheim
sex
male
tissue
Dermal fibroblast
cell_line
CIMH-NP-3
health_state
healthy
BioSampleModel
Human