Bacteroides uniformis
ENA first public
2024-09-21
INSDC center name
EMBL Heidelberg
INSDC status
public
Submitter Id
spire_mag_01730421
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
megahit 1.2.9
binning parameters
default
binning software
metabat 2.12.1
broad-scale environmental context
human digestive system
broker name
EBI-EMG
collection date
2017-09-01
completeness score
85.49
completeness software
checkm2 0.1.3
contamination score
3.69
environmental medium
not provided
geographic location (country and/or sea)
China
geographic location (latitude)
39.90000000
geographic location (longitude)
116.30000000
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
local environmental context
human gut
metagenomic source
human gut metagenome
project name
With the establishment of the heart-gut axis concept, accumulating studies suggest that the gut microbiome plays an important role in the genesis of cardiovascular diseases. Yet, little evidence has been reported characterizing the gut microbiota shift in correspondence to arrhythmia, particularly in atrial fibrillation, the most common type of cardiac arrhythmia with worldwide prevalence. We include the first result of the global alterations that occur in the intestinal microbiota based on a strategy of metagenomic and metabolomic analyses. Our findings characterize the disordered gut microbiota and microbial metabolite profiles in atrial fibrillation. Intervention strategies targeting microbiome composition to counteract the progression of atrial fibrillation are highly suggested.
sample derived from
SAMEA4867841
sample name
spire_mag_01730421
scientific_name
Bacteroides uniformis
sequencing method
Illumina NovaSeq 6000
taxonomic identity marker
multi-marker approach