Bacteroides uniformis
ENA first public
2024-09-21
INSDC center name
EMBL Heidelberg
INSDC status
public
Submitter Id
spire_mag_01089317
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
megahit 1.2.9
binning parameters
default
binning software
metabat 2.12.1
broad-scale environmental context
human digestive system
broker name
EBI-EMG
collection date
2013/2015
completeness score
66.22
completeness software
checkm2 0.1.3
contamination score
3.75
environmental medium
stool
geographic location (country and/or sea)
Germany
geographic location (latitude)
50.942911
geographic location (longitude)
6.967314
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
local environmental context
human gut
metagenomic source
human gut metagenome
project name
Parkinson's disease (PD) presently is conceptualized as a protein aggregation disease in which pathology involves both, the enteric and the central nervous system, possibly spreading from one to another via the vagus nerves. As gastrointestinal dysfunction often precedes or parallels motor symptoms, the enteric system with its vast diversity of microorganisms may be involved in PD pathogenesis. Alterations in the enteric microbial taxonomic level of L-DOPA-naïve PD patients might also serve as a biomarker.We thus compared the fecal microbiomes of 31 early stage, L-DOPA-naive PD subjects to 28 age matched controls by metagenomic analysis.
sample derived from
SAMEA103958115
sample name
spire_mag_01089317
scientific_name
Bacteroides uniformis
sequencing method
Illumina HiSeq 2500
taxonomic identity marker
multi-marker approach