Bacteroides uniformis
ENA first public
2024-09-21
INSDC center name
EMBL Heidelberg
INSDC status
public
Submitter Id
spire_mag_00895384
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
megahit 1.2.9
binning parameters
default
binning software
metabat 2.12.1
broad-scale environmental context
human digestive system
broker name
EBI-EMG
collection date
2015-10
completeness score
94.03
completeness software
checkm2 0.1.3
contamination score
4.17
environmental medium
stool
geographic location (country and/or sea)
China
geographic location (latitude)
30.30000000
geographic location (longitude)
120.20000000
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
local environmental context
human gut
metagenomic source
human gut metagenome
project name
Gut microbiome make contributions to human host, and intestinal dysbiosis is associated with rheumatoid arthritis. Here we firstly demonstrated that the human gut microbiome related to rheumatoid arthritis could be divided into subtyping groups under different human enterotypes, which indicate the associations between rheumatoid arthritis and gut microbiome were diverse. In rheumatoid arthritis-related microbiota, Prevotella could be an indicator of early rheumatoid arthritis patients but insufficient to differentiate RA patients from healthy controls, and Bacteroides coprocola enriched in group 3 and Bacteroides dorei enriched in group 4 were considered to be as indicators of serious rheumatoid arthritis patients. Our findings provide additional evidences supporting that rheumatoid arthritis is a heterogeneous disease. Thus, the study of association between disease and gut microbiome should be conducted under different human gut enterotypes.
sample derived from
SAMN06112085
sample name
spire_mag_00895384
scientific_name
Bacteroides uniformis
sequencing method
Illumina HiSeq 2000
taxonomic identity marker
multi-marker approach