Bacteroides uniformis
ENA first public
2024-09-21
INSDC center name
EMBL Heidelberg
INSDC status
public
Submitter Id
spire_mag_00779575
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
megahit 1.2.9
binning parameters
default
binning software
metabat 2.12.1
broad-scale environmental context
human digestive system
broker name
EBI-EMG
collection date
2017
completeness score
73.76
completeness software
checkm2 0.1.3
contamination score
0.48
environmental medium
stool
geographic location (country and/or sea)
China
geographic location (latitude)
missing: third party data
geographic location (longitude)
missing: third party data
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
local environmental context
human gut
metagenomic source
human gut metagenome
project name
Public description： Ankylosing spondylitis (AS) is a common autoimmune disease. Due to the early pathogenesis and long duration, patients suffer from morning stiffness, low back pain, chest pain, alternating hip pain and other symptoms. And the disability rate is high, which seriously affects the quality of life. According to statistics, the prevalence of ankylosing spondylitis in China is about 0.3%, mostly young men. On average, patients need to stop working after fifteen or six years of illness. After 20 years of illness, more than 85% of patients lose the ability to live independently and become so-called "puppet people." In response to key scientific issues, these datas is devoted to the use a metagenomic wide association studies to explore new key biomarkers and therapeutic targets of AS from intestinal micro-organisms, so as to improve early diagnosis, accurate prediction and classification, and improve prognosis.And combine with other datas which already published of autoimmune disease,we identified conflicts and contradicts points of RA ,AS ,behcet disease and T1D.
sample derived from
SAMEA5054132
sample name
spire_mag_00779575
scientific_name
Bacteroides uniformis
sequencing method
Illumina HiSeq 2000
taxonomic identity marker
multi-marker approach