Bacteroides uniformis
ENA first public
2024-09-21
INSDC center name
EMBL Heidelberg
INSDC status
public
Submitter Id
spire_mag_00888233
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
megahit 1.2.9
binning parameters
default
binning software
metabat 2.12.1
broad-scale environmental context
human digestive system
broker name
EBI-EMG
collection date
2013
completeness score
90.98
completeness software
checkm2 0.1.3
contamination score
1.6
environmental medium
stool
geographic location (country and/or sea)
Austria
geographic location (latitude)
47.80151
geographic location (longitude)
13.04292
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
local environmental context
human gut
metagenomic source
human gut metagenome
project name
Colorectal cancer, a commonly diagnosed cancer in the elderly, often develops slowly from benign polyps called adenoma. The gut microbiota, with its critical roles in nutrient metabolism and immune modulation, is believed to be directly involved in colorectal carcinogenesis. The identity and functional capacity of the adenoma- or carcinoma-related gut microbe(s), however, have not been surveyed in a comprehensive manner. Here we perform metagenomewide association study (MGWAS) on stools from healthy controls, advanced adenoma and carcinoma patients, revealing gene markers from over 100 bacterial strains enriched in each group.
sample derived from
SAMEA3136653
sample name
spire_mag_00888233
scientific_name
Bacteroides uniformis
sequencing method
Illumina HiSeq 2000
taxonomic identity marker
multi-marker approach