Bacteroides uniformis
ENA first public
2024-09-21
INSDC center name
EMBL Heidelberg
INSDC status
public
Submitter Id
spire_mag_01020735
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
megahit 1.2.9
binning parameters
default
binning software
metabat 2.12.1
broad-scale environmental context
human digestive system
broker name
EBI-EMG
collection date
2014-08-04
completeness score
85.4
completeness software
checkm2 0.1.3
contamination score
0.99
environmental medium
not provided
geographic location (country and/or sea)
Denmark
geographic location (latitude)
55.69813700
geographic location (longitude)
12.56136100
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
local environmental context
human gut
metagenomic source
human gut metagenome
project name
We have recently published data regarding a randomized cross-over intervention using AXOS and poly-unsaturated fatty acids (PUFA) on a cohort of subjects with overweight and metabolic syndrome (MetS). By using a bacterial 16S amplicons based approach we observed the already known bifidogenic effect of AXOS in the human gut. Moreover, we showed for the first time that intake of ~10 g/day AXOS, for 4 weeks, drives significant changes in the structure of the human gut microbiota as a whole by concomitantly increasing the abundance of pivotal species for butyrate production. Our data also indicated that minor effects of AXOS intake had place at physiological and metabolic levels by inspection of several clinical parameters. As a consequence, we aimed the present study to characterize a more detailed response from the human body to AXOS in order to gain insights with respect to the less visible metabolic effects associated with consumption of this type of dietary fiber. For such aim, we have analyzed the group of responders to AXOS consumption (to whom the gut microbiota was significantly altered) from our early study (first period/arm of the AXOS cross-over design).Registration: Registered under ClinicalTrials.gov Identifier no.NCT02215343
sample derived from
SAMEA104725000
sample name
spire_mag_01020735
scientific_name
Bacteroides uniformis
sequencing method
Illumina HiSeq 2500
taxonomic identity marker
multi-marker approach