Mus musculus
10-12-week-old females C57BL/6 WT mice were inoculated subcutaneously (ectopic) on the right flank with 4 × 106 cells for the MOC1 cells (HPV-negative head and neck cancer). TCR β-chain sequencing was performed by utilizing whole RNA extracted from MOC1 tumor samples by using a quantitative experimental and computational TCR sequencing pipeline described previously [Oakes et al. Front Immunol, 2017].
strain
C57BL/6
isolate
ATRi/RT/aPDL1/aNKG2A, biological replicate 3
breed
not applicable
cultivar
not applicable
ecotype
not applicable
age
10-12 weeks
dev_stage
adult
collection_date
2022-12-02
geo_loc_name
United Kingdom: London
sex
female
tissue
tumor
genotype
WT
biomaterial_provider
Institute of Cancer Research, London, UK
cell_line
MOC1
disease
head and neck squamous cells carcinoma
treatment
ATRi/RT/aPDL1/aNKG2A
BioSampleModel
Model organism or animal