Caenorhabditis elegans
Caenorhabditis elegans (N2 Bristol) was kept in M9 buffer with or without water-soluble fraction of the hydroalcoholic extract of Withania somnifera root. The worm population maintained in presence of extract registered higher survival rate than the control worms maintained in absence of extract over a period of 11 days. Progeny formation was displayed by the worm population in presence of the extract, but not in its absence. Molecular mechanisms of this pro-longevity and pro-fertility effect of W. somnifera extract on the nematode worm was elucidated through whole transcriptome analysis.
strain
N2 Bristol
dev_stage
L3-L4 stage
collection_date
2023-05-15
geo_loc_name
India: Gujarat
sex
hermaphrodite
tissue
Whole organism
BioSampleModel
Model organism or animal