Parse Evercode WT scRNA-seq — mouse CD11b+ myeloid, shLOX KD rep 1 (shLOX-I-1)
Mus musculus
source_name
subcutaneous tumor xenograft (CD11b+ tumor-infiltrating myeloid fraction, Rag1-/- host)
tissue
subcutaneous tumor xenograft (CD11b+ tumor-infiltrating myeloid fraction, Rag1-/- host)
cell line
primary cells (no cell line)
cell type
CD11b+ tumor-associated myeloid cells (mouse host)
genotype
Rag1-/- host (B6.129S7-Rag1tm1Mom/J); paired tumor genotype = MCF10DCIS.com + pLKO-LOX shRNA
treatment
CD11b+ tumor-associated myeloid cells host-infiltrated into the matched xenograft tumor (mouse 169877 - M3, left flank). Tumor implanted via aged C57BL/6 mouse breast dECM scaffold seeded with MCF10DCIS.com cells (paired tumor genotype = shLOX KD); harvested at week 7 post-implantation (matched tumor volume 134 mm^3). CD11b+ magnetic-bead enrichment from the dissociated tumor.
batch
S1_WT_A1+S2_WT_B1+S3_WT_C1+S4_WT_D1+S5_WT_E1+S6_WT_F1+S7_WT_G1+S8_WT_H1
geo_loc_name
missing
collection_date
missing