Metagenome-assembled genome: MGYG000045725
Eubacteriales bacterium
This sample represents a Third Party Annotation (TPA) Metagenome-assembled genome generated from the metagenomic sample ERS199155 of study ERP002061.
ENA first public
2026-06-12
INSDC center name
EMG
INSDC status
public
Submitter Id
MGYG000045725
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
missing: third party data
binning parameters
missing: third party data
binning software
missing: third party data
broad-scale environmental context
human-associated habitat
broker name
EBI-EMG
collection date
2008/2010
completeness score
99.28
completeness software
CheckM2_v1.1.0
contamination score
0.02
environmental medium
faeces
geographic location (country and/or sea)
Denmark
geographic location (latitude)
55.67609700
geographic location (longitude)
12.56833700
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
local environmental context
human gut
metagenomic source
human gut metagenome
project name
The microbial diversity of environments like the human gut extends far beyond what is covered by reference genomes. Here we present a method for exhaustive and unsupervised co-abundance gene binning across a series of highly complex metagenomic samples. As the method does not rely on previously sequenced reference genomes it allows for discovery of new species, viruses and clonal heterogeneity. We demonstrate the method on human gut microbiome data and identify 7,381 co-abundance gene groups (CAGs) ranging in size from 3 to 6,319 genes. The CAGs represent a wide variety of biological entities including microbial genomes, phages and clonal differences. We name the 741 largest of these metagenomic species (MGS), because they correspond to microbial species. In addition, we establish microbial host affiliations by dependency-associations for many small CAGs. Longitudinal sampling in the same individuals indicates that some of these dependency-associations are important for the persistence of their microbial host
sample derived from
ERS199155
sample name
MGYG000045725
scientific_name
Eubacteriales bacterium
sequencing method
missing: third party data
taxonomic identity marker
multi-marker approach