Hu-PBMC-humanized NCG mouse glioma tumor scRNA-seq, DAP12 replicate 01
Mus musculus
Single-cell RNA sequencing of dissociated subcutaneous glioma tumor tissue from a Hu-PBMC-humanized NCG mouse. Treatment group: DAP12; biological replicate: 01. GEX FASTQ only; oligo/hash-tag libraries were not submitted. This sample belongs to a GD2-targeted CAR macrophage study comparing NC, CD3z CAR-M, DAP12 CAR-M, and MYD88 groups.
strain
NCG mouse
age
not collected
dev_stage
adult
collection_date
not collected
geo_loc_name
China: Anhui
sex
not collected
tissue
subcutaneous glioma tumor
biomaterial_provider
Anhui Medical University
cell_line
U87
cell_type
single-cell suspension from tumor tissue
collected_by
Lucheng Zhou, Xinlei Chen, Zhihao Xu, Yizhao Chen, Ruiqiang Du, Shuai Wang, Mengjuan Zhu, Jiaqi Qiu, Fei Tan, Wenming Hong, Jiajie Tu, Ning Lin
disease
glioma xenograft
genotype
Hu-PBMC-humanized NCG mouse
growth_protocol
U87 glioma cells were implanted subcutaneously in Hu-PBMC-humanized NCG mice and tumors were collected after treatment with GD2-targeted CAR macrophages or control treatment.
health_state
tumor-bearing
isolation_source
dissociated subcutaneous glioma tumor tissue
phenotype
humanized mouse glioma xenograft model
sample_type
tumor tissue
treatment
DAP12
treatment_group
DAP12
biological_replicate
01
host
Hu-PBMC-humanized NCG mouse
library_note
GEX FASTQ only; oligo/hash-tag libraries were not submitted.
BioSampleModel
Model organism or animal
submitted_sample_id
3