Human metagenome of Pleural fluid
human metagenome
As part of diagnosing a pleural fluid sample with suspicion of Mycobacterium tuberculosis using whole genome sequencing, we obtained a complete/near-complete genome of Tsukamurella tyrosinosolvans. Tuberculous pleuritis is a common extrapulmonary manifestation often presented with nonspecific symptoms. Misidentification of Tsukamurella as Mycobacterium tuberculosis is a well-recognized diagnostic challenge because the two genera share several morphological, biochemical, and clinical features. This particular sample showed acid-fast filamentous, Gram-positive cells, and showed growth in Mycobacteria Growth Indicator Tube (MGIT) from which DNA was extracted for sequencing. This genome can be explored for further studies on pathogenicity of this species.
host
Homo sapiens
isolation_source
Pleural fluid
collection_date
2025-08-11
geo_loc_name
India: Meerut
lat_lon
28.98 N 77.70 E
BioSampleModel
Metagenome or environmental