Mus musculus
strain
not applicable
isolate
CKD-HFpEF1: C57BL/6J mice at 10 weeks of age underwent 5/6 nephrectomy. In the following two weeks, 2/3 nephrectomy of the left kidney and total nephrectomy of the right kidney were performed respectively. Subsequently, they were fed with water containing L-nitroarginine Methyl Ester(L-NAME, 0.5g/L) and a high-fat diet (60% high-fat). The left ventricular myocardial tissue of mice was extracted 12 weeks later.
breed
C57BL/6J
cultivar
not applicable
ecotype
not applicable
age
24 week
dev_stage
CKD-HFpEF1: The mice exhibited more severe heart failure with preserved ejection fraction.
collection_date
2024-12-27
geo_loc_name
China
sex
male
tissue
heart
BioSampleModel
Model organism or animal