Mus musculus
This sample comprises B cells isolated from a single BALB/c mouse following immunization and enrichment using human PD-1 antigen. The cells were used for high-throughput single-cell VDJ sequencing to characterize the antibody repertoire. The dataset includes raw sequencing reads. This sample enables analysis of naturally paired antibodies derived from plasma cells, providing insights into affinity-matured, antigen-specific immune responses. All procedures were performed in accordance with relevant ethical guidelines for animal research.
strain
BALB/c
isolate
Single mouse
age
20 weeks
dev_stage
Adult
collection_date
2022-09-01
geo_loc_name
China: Shanghai
sex
female
tissue
spleen
treatment
Antigen-specific B cell enrichment using human PD-1 protein
BioSampleModel
Model organism or animal