B16/BL6 melanoma TILs, untreated control, mouse M3
strain
C57BL/6
isolate
not collected
breed
not collected
cultivar
not collected
ecotype
not collected
age
approx. 10-15 weeks at collection
dev_stage
adult
collection_date
2020-12-01
geo_loc_name
United Kingdom: London
sex
female
tissue
melanoma tumor
biomaterial_provider
UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK
collected_by
Quezada laboratory, UCL Cancer Institute
disease
melanoma
genotype
wild type
growth_protocol
50,000 B16/BL6 melanoma cells implanted intradermally (right flank) on day 0; no immunotherapy administered
health_state
tumor-bearing
isolation_source
B16/BL6 melanoma tumor, intradermal, right flank
treatment
none (untreated tumor-bearing control)
tumor_model
B16/BL6 melanoma (intradermal, C57BL/6)
response_phase
untreated control (no immunotherapy)
collection_timepoint
untreated control, mouse 3
sorted_populations
Tumor-infiltrating T cells (sorted live CD45+CD3+CD5+) and myeloid/non-T-non-B cells (sorted live CD45+CD5-CD19-), processed as separate 10x libraries from the same tumor
assay
10x Chromium Next GEM 5' scRNA-seq + paired scTCR-seq (V(D)J)
BioSampleModel
Model organism or animal