sequencing of K18-hACE2 mice infected with recombinant adenovirus expressing  S protein of SARS-CoV-2
This study aims to establish a controllable biosafety model for SARS-CoV-2 infection in mice expressing human ACE2 receptor (K18-hACE2) using a recombinant adenovirus, and study the therapeutic potential of HSBDG on this mouse model.