Screening results of a random peptide-displaying phage library
N-terminus 15 amino acid (MC16) of Annexin A1 (ANXA1) is an effective therapeutic target for tumors and tumor vasculature as it specifically localizes to the cell surface of tumor cells and tumor vascular endothelial cells. We identified the D-type peptide (hpnevrs, dhp7) by mirror-image phage display targeting L-type MC16. The dhp7 bound specifically to L-type MC16 (KD 0.48 uM) but did not bind to D-type MC16 and mutant L-type MC16. Both in vitro and in silico interaction analyses indicate that the alpha-helix of the L-type MC16 may be important for dhp7 binding. Here, FASTQ files containing the NGS analysis results of linear peptides consisting of seven amino acids are stored.