Gene expression of hippocampus from 9-month-old wildtype mice with sham/400 mGy X-ray irradiation treatment and 9-month-old 3xTg-AD mice with sham/400 mGy  X-ray irradiation treatment
Current study aimed to identify the 400 mGy X-ray irradiation-induced unique gene expression changes in the hippocampus of the 9-month-old 3xTg-AD mice. Overall design: The 5.5-month-old 3xTg-AD mice and the age-matched wildtype mice received biweekly X-ray irradiation at 50 mGy/sham irradiation 8 times. When the mice reached 9-month-old, the hippocampus from different treatment groups was harvested for bulk RNA sequencing (n=3 from each treatment group), and a total of 12 samples were analyzed.