Full inactivation of DYRK1A in heterozygous embryonic forebrain at E15.5
we analyzed gene expression in E15.5 Dyrk1a<+/-> forebrains and compared it to control littermates. Overall design: Forebrains from control (wt) and mutant (Dyrk1a<+/->) mice (n=3 per genotypes) were microdissected at the age of 15.5 days post coitum (E15.5) from the Dyrk1a<+/-> line.