CUT&Tag profiling of Irx3 binding sites in AC16 cardiomyocytes supporting studies on cardiac regulatory mechanisms
This dataset presents CUT&Tag sequencing data targeting the transcription factor Irx3 in human AC16 cardiomyocytes (encompassing both IgG control and Irx3-overexpressing groups), which profiles the genome-wide binding landscape of Irx3. This dataset is shared across two research manuscripts: Modulation of Ferroptosis by the Irx3--Etfa Pathway Protects Against Cardiac Hypertrophy and Irx3 Ameliorates Post-Myocardial Infarction Cardiac Dysfunction by Regulating Both Inflammatory and Fibrotic Pathways. It serves to support investigations into distinct facets of Irx3-mediated regulatory mechanisms in cardiac physiology and pathology.