Biliary Microbiota and Bile Acid Remodeling in Common Bile Duct Stone Patients: A Multi-Omics Analysis of ERCP-Acquired Human Bile
Methods: Bile samples collected during ERCP from 25 patients (12 CBD stones; 13 controls) were analyzed by 16S rRNA sequencing and targeted bile acid metabolomics, followed by between-group comparisons and exploratory microbe-metabolite correlation analyses.