The self-renewal function of Oct-4 can be replaced by the EWS-OCT-4 fusion protein in embryonic stem cells
EWS-Oct-4 can effectively replace Oct-4, which has significant implications for advancements in stem cell research and regenerative medicine Overall design: we used J1 ESC cell line as control group, and EWS-OCT4, OCT4 stable cell line as an experimental group.  All experiments are triplicated.