Dynamicomic analysis reveals the biocontrol activity of a Streptomyces avermitilis SM12 against Fusarium spp.
The integration of multi-omics approaches has significantly expanded the scope of microbial functional characterization, establishing a systems biology framework for discovering novel bioactive compounds and elucidating their mechanisms of action. This study focused on Streptomyces avermitilis SM12, a strain with prolific secondary metabolism; its metabolites demonstrate broad-spectrum antifungal activity against phytopathogens through multimodal mechanisms.