Whole-Genome Sequencing of Extended-Spectrum Beta-Lactamase-producing Escherichia coli Strains Isolated from Patients at HCTM and Indonesian Migrant Workers
Antimicrobial resistance (AMR) is a growing global health crisis that threatens the effectiveness of both frontline and reserve antibiotics. Among the most concerning resistant pathogen is Extended-Spectrum Beta-Lactamase (ESBL)-producing Escherichia coli (ESBLEC). In this study, we characterized ESBLEC strains isolated from patients at HCTM and Indonesian migrant workers. Whole-genome sequencing (WGS) was performed, and antimicrobial resistance determinants and sequence types (STs) were compared. These findings provide important insights for the surveillance of these pathogens and help inform more effective control strategies.