The alterations of gene expression profiling induced by ORM1 knockdown in HCT116 cells.
Recently, ORM1 was found to play an oncogenic role in in several cancers. Here we report gene expression profiles of HCT116 cells treated with ORM1 siRNA. This study reveals a novel role of ORM1 in downstream gene regulation and provides a new explanation of ORM1' s function in colorectal cancer. Overall design: RNA-seq after knockdown of ORM1 by siRNA in HCT116 cells.