Mutations from IPEX patients elicit a range of phenotypes in mice [scATAC-Seq]
scATAC analysis of mouse Treg from Foxp3 missense mutant mice heterozygous females : R51Q, K199del, R51Q, WT Overall design: Mouse CD4+ regulatory Tregs in 6-10 weeks old Foxp3 missense mutant heterozygous female mice were isolated from spleen by FACS for scATAC-seq using 10x Genomics.