Laetiporus sulphureus Polysaccharides Mitigate Colitis by Reshaping  the Gut Microbiota and Regulating Immune Responses
Conclusion: LSP exerts multi-targeted protection against colitis by reinforcingepithelial barrier function, attenuating inflammation, and reshaping gut microbialecology. These findings highlight LSP as a promising natural therapeutic candidate forIBD. Further metabolomic and meta transcriptomic analyses are warranted to elucidatethe microbial metabolites and molecular pathways mediating these protective effects.