LncRNA CARINH regulates expression and function of innate transcription factor IRF1 in macrophages [RNA-Seq 2]
The antisense lncRNA CARINH acts as an additional regulatory layer of antiviral immunity through coordinated regulation of the transcription factor IRF1 and downstream interferon-stimulated genes. Overall design: Mice were inoculated with influenza strain PR8 and were euthanized 4 days later. Lungs were harvested and snapfrozen. Four mice of each groups were used.