RNAseq of livers from WT mice or livers with Rbfox2 knockout fed CD
Rbfox2 is required for maintaining hepatic metabolic homeostasis, here we carry out RNAseq to of WT and aged matched littermate Rbfox2 knockout mice under high fructose in order to determine changes in alternative splicing and mRNA expression caused by knockout of this splicing factor in this metabolic environment. Overall design: RNAseq of liver tissue from control diet and high fat diet (60% cal. from fat) mice harvested under fasted (16h) status