Targeted CRISPR-Cas9 screens identifying drivers and repressors of cisplatin sensitivity
These raw sequencing data relate to the manuscript entitled "RPA exhaustion activates SLFN11 to eliminate cells with heightened replication stress". These data were generated by sequencing sgRNAs integrated into genomic DNA harvested over the course of a series of targeted and pooled CRISPR-Cas9 dropout screens aimed at identifying novel drivers and repressors of cisplatin sensitivity in the eHAP cell line.