Genomic analysis of enterotoxigenic Esherichia coli (ETEC) samples from Nepal
Enterotoxigenic Escherichia coli (ETEC) is an important pathotype that is a leading cause of both acute infant diarrhoea, and traveller's diarrhoea in Nepal. ETEC samples are defined by their ability to express one or both of heat-labile (LT) or heat-stabile (ST) enterotoxins, as well as colonisation factors (CFs) that facilitate attachment in the small intestine. Here we aim to characterise the genomic properties of over 300 ETEC samples collected from patients presenting at a travel clinic in Kathmandu, Nepal, over a period of 28 years.