ChIP-seq of ESCC Cells Overexpressed TFAP2ß or its LLPS-deficient Mutants
This dataset contains raw ChIP-seq data from esophageal squamous cell carcinoma (ESCC) cells overexpressing TFAP2ß or its LLPS-deficient mutants (?IDR3 or Mut_IDR3). The experiment aims to explore the chromatin binding profiles of TFAP2ß and its phase separation-deficient mutants to uncover the role of TFAP2ß's LLPS activity in regulating gene expression in ESCC. Data were collected from the genomic binding of TFAP2ß and its LLPS-deficient mutants, providing insights into the regulatory networks controlled by TFAP2ß in cancer progression. Overall design: ChIP-seq of TFAP2ß or LLPS-deficient mutants (?IDR3 or Mut_IDR3) in ESCC cells KYSE150 to understand the chromatin binding dynamics and regulatory activity associated with TFAP2ß's phase separation mechanism.