Multi-Omics integration reveals that Emodin enhances resistance to Aeromonas hydrophila in Yellow River Carp (Cyprinus carpio haematopterus) by modulating the gut microbiota-metabolism-immune Axis
We aim to address two central questions: Whether emodin directly inhibits the expression of quorum sensing-related virulence genes in A. hydrophila; and how emodin exerts systemic protection by remodeling the intestinal microbial communit, subsequently influencing the host metabolic profile, and ultimately coordinating the immune and antioxidant defense networks.