Transcriptome profiling of human and murine hepatic cells with inducible HBV replication
This project generates RNA-seq transcriptomic profiles from a panel of inducible Tet-off HBV-replicating human and murine hepatic cell lines. Samples include human hepatoma lines Huh7, murine hepatocyte lines AML12 and H2.35, and murine hepatoma line Hepa1-6 engineered with a tetracycline-repressible HBV replication cassette. Samples were analyzed to capture HBV replication-associated changes in host gene expression within each line.