Intestinal bacteria-derived tryptamine and its impact on human gut microbiota
Tryptamine is a neuromodulator derived from tryptophan that has been shown to significantly impact the host gut homeostasis through its production by the gut microbiota. In this study, we examined the impact of tryptamine on the composition and function of four healthy human gut microbiota (two toddlers and two adults) by conducting 48 h ex vivo fecal batch fermentations.