Transcriptomic profiling of wild-type cells and H3K4A, ero1-1, ero1-1 H3K4A mutants under oxidative folding stress
This project contains RNA-seq data generated to investigate how the loss of H3K4me affects transcriptional responses during stress adaptation in yeast. Transcriptomes of wild-type, H3K4A, ero1-1 and ero1-1 H3K4A strains were profiled after exposure to tunicamycin-induced stress (30 degree) or heat stress (35 degree), as well as in untreated controls (25 degree). The data identify stress-induced gene expression programs and evaluate the contribution of H3K4me to transcriptional regulation under oxidative folding stress.