Common lymphoid progenitor derivation of plasmacytoid dendritic cells is mediated by Bcl11a
Plasmacytoid dendritic cells (pDC) specialize in type I interferon production to coordinate innate and adaptive immunity. We identify two pDC subsets in vivo, evaluate their genome-wide expression, and demonstrate a developmental requirement for Bcl11a to provide insight into this enigmatic cell type. Overall design: Sorted Pdca1+ BM cells from WT naïve C57/BL6 mice and did 10x single cell seq