The effect of STING antagonist SN-011 on the gene expression changes in the mouse brain after ischemic stroke
Mounting evidence indicates that the cGAS-STING pathway represents the major DNA sensing pathway to invoke immune and inflammatory responses in neuroinflammatory disorders. Here, we examined the effect of STING antagonist SN-011 on the gene expression changes in the mouse brain after ischemic stroke Overall design: Total RNA of mouse brain were sequenced by deep sequencing using Illumina HiSeq 2500