Alteration of gene expression in ubr-5(-) and pabp-2(RNAi)
To investigate how UBR-5 and PABP-2 affect gene expression profile, we generated ubr-5(-) c elegans mutant and performed RNA seq in combination with pabp-2(RNAi). Overall design: We compared gene expression profile of wild type (A), pabp-2(RNAi) (B), ubr-5(-) (C) and ubr-5(-) pabp-2(RNAi) (D). glmLRT.txt: Files with Di?erential expressed gene list (as indicated in the corresponding sample description field) igenomes.genes_normalized.counts.CPM.tab, normalized counts Grant 3: Welch Foundation I-2022-20190330 Regulation of Non-Canonical Caspase Functions by Distinct Protein Complexes