Metabolic dependencies of metastasis-initiating cells in breast cancer [ChIP-Seq]
We investigated the changes in acetylation peaks on H3K27ac in cells in response to inhibitors that alter the activity of acetyl-coa generating enzymes Overall design: H3K27ac ChIP-Seq on cells that have been treated in vitro for 48 hours with vehicle, acetate, etomoxir, acetate+etomoxir, etomoxir+SB204990, and acetate+etomoxir+SB204990