Tumor progression is independent of tumor associated macrophages in two lineage-based mouse models of GBM [TAMdepletedVsControl RNAseq]
We investigate the transcriptomic changes resulting from TAM depletion in Type 1 and Type 2 GBMs We perform bulk RNAseq on TAM depleted and Control Type 1 and Type 2 GBM bulk tumor tissue Overall design: 5 Type 1 Control tumors, 3 Type 1 TAM depleted tumors, 4 Type 2 Control tumors, 4 Type 2 TAM depleted Tumors