The effects of sorafenib treatment on the CD4+T cell population
To investigate the impact of sorafenib treatment on gene expression in CD4+T cells, we performed RNA sequencing on CD4+T cells treated with sorafenib and on control CD4+T cells that were not treated with sorafenib. Specifically, our study focused on the expression of immune related genes, and we observed an downregulation in the expression of TCR genes. Overall design: Comparative gene expression profiling analysis of RNA-seq data for sorafenib treated Treg cell and non-sorafenib treated cell.