High-Throughput Exome Sequencing Identified RUNX1 as a Potential Prognostic Marker for Pediatric Nephroblastoma
This study aimed to explore somatic variants present in Wilms tumor (WT) and other pediatric renal tumors, using next-generation technology with archival biological samples in order to validate the findings reported in recent studies, identify recurrent drivers that could potentially be linked to clinical outcomes, and discover markers that might serve as indicators for novel therapeutic strategies.