Intestinal and Nasopharyngeal Microbiota Analysis of Children with Meningococcemia in Pediatric Intensive Care Unit: INMACS-PICU Study
In this prospective, multi-center study, 10 children with meningococcemia and 10 age-matched healthy controls were included. Nasopharyngeal and fecal samples were obtained at admission to the intensive care unit and on the tenth day of their hospital stay. The V3 and V4 regions of the 16S rRNA gene were amplified following the 16S Metagenomic Sequencing Library Preparation.