Proteogenomic profiling of thymic and pulmonary neuroendocrine neoplasia.
This study represents a proteomic resource for thymic and pulmonary neuroendocrine neoplasia (NEN) with genetic and quantitative protein / RNA expression data for 6600 proteins and provides a proteomicgenomic diagnostic signature for classification of low and high grade NEN. We characterized a cohort of 54 and 22 low and high grade NEN, respectively of both thymic and pulmonary origin.