scRNA-seq of T cell differentiation in Artificial Thymic Organoids
We followed the PSC-ATO protocol as previously described in Montel-Hagen et al. 2019, and differentiated from two iPSC lines, HPSI0114i-kolf_2 (Kolf) and HPSI0514i-fiaj_1 (Fiaj), to single positive T cells. The following include scRNA-seq data from intermediate cells sampled at day -14, day -7 (two samples), day 0 and week 1 of the protocol. For data of later time points (week 3, 5 and 7), please see accession number E-MTAB-11343.