CUT&Tag analysis on H3K4me3 in mouse bone marrow macrophages (BMMs) under deletion of Ash1l gene
To investigate the role of Ash1l in the regulation of osteoclast differentiation, we carry out CUT&amp;Tag experiments to analyze the genome-wide distribution patterns of the H3K4me3 modification in the bone marrow-derived macrophages (BMMs) obtained from Ash1lfl/fl; LysM-Cre+ mice (cKO), as well as their wild-type (WT) counterparts.