Genomic profiling of highly aggressive musculoskeletal sarcomas identifies potential therapeutic targets: a single-center experience
The clinical heterogeneity of sarcomas together with the complexity of their genomic landscape have severely limited novel therapeutic opportunities. We report on our experience at the IRCCS Istituto Ortopedico Rizzoli using targeted gene sequencing for genome profiling with the intent of identifying potential actionable targets. We analyzed 22 advanced sarcoma patients.