Role of Mcam in breast cancer cell state using a model cell line (Py230) [single cell]
Morphological changes suggested cell state switching and scRNASeq profiles were therefore generated to use in downstream comparative transcriptomics analysis and for identification of cell state regulators. Overall design: Py230 cells with LV-shControl vs LV-shMcam cells were isolated from 2D cell culture and analyzed using scRNAseq via chromium 10x protocols