Sequencing of the upper respiratory tract microbiota in children with pneumonia caused by mycoplasma
This study aims to investigate the upper respiratory microbiota composition and immune status in children with refractory Mycoplasma pneumoniae pneumonia (RMPP) compared to general MPP (GMPP). Nasopharyngeal swabs were collected from pediatric patients for 16S rRNA gene sequencing (V4 hypervariable region) to identify microbial dysbiosis associated with disease severity. This research provides insights into the pathogenesis of RMPP and potential therapeutic targets.