Enhancing tumor-specific recognition of programmable synthetic bacterial consortia for targeted colorectal cancer therapy
Based on E.coli Nissle 1917, we constructed engineered synthetic bacterial consortia (SynCon) that can sense the tumor microenvironment and release payloads. The data uploaded here are 16S rRNA sequencing results of gut microbiota in AOM/DSS mouse models after the intervention of these SynCon.