Lacticaseibacillus paracasei BNCC345679 ameliorate DSS colitis through modulation of gut microbiome, colitis associated miRNA and inflammation response
In this project, the beneficial role and mechanisms of the probiotic strain Lacticaseibacillus paracasei BNCC345679 have been studied in ulcerative colitis mice using dextran sodium sulphate (DSS) model. Male C57JBL/6 mice were randomly divided into threegroups: Normal group, dextran sulphate sodium (DSS) group, and DSS+Lacticaseibacillus paracasei BNCC345679 group called DP group.Mice were fed L. paracasei BNCC345679 and feces samples were collected to examine changes in gut microbiota.