Dhx16 regulates alternative splicing of pre-mRNA in hematopoietic stem cells [ISO-Seq]
To investigate whether Dhx16 knockout affects alternative splicing of pre-mRNA in HSCs, we sorted Dhx16-deficient and control HSCs and performed ISO-Seq for full-length transcriptome sequencing. Overall design: The full-length transcriptome sequencing of HSC in Control and Dhx16-knockout mice based on the PacBio third-generation sequencing platform