Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem cells via Wnt receptor endocytosis
Mucin-type O-glycosylation regulates mouse embryonic stem cells pluripotency by directly modulating the endocytosis of the Wnt receptor Frizzled-5, finely tuning Wnt signaling outcome. Overall design: RNA-seq to examine galectins and Znrf3/Rnf43 expression in 1 technical and biological replicate of WT R1 mouse ESC cell line