CKD patient genetic and epigenetic profiling
chronic Kidney Disease (CKD) is a progressive condition characterized by gradual loss of kidney function over time. This study investigates both genetic and epigenetic factors associated with CKD in affected patients compared to healthy controls. Whole-exome sequencing and methylation profiling were performed to identify structural variations, single nucleotide polymorphisms (SNPs), and DNA methylation changes that may contribute to disease susceptibility and progression. The results aim to provide insights into the molecular mechanisms underlying CKD, identify potential biomarkers for early detection, and support the development of personalized therapeutic strategies. Functional genome annotation will be provided to describe the impact of identified variants on gene function and biological pathways.