Microbiome landscape in advanced solid tumors: a SCRUM-Japan MONSTAR-SCREEN study
We investigated the association between the microbiome and clinical features across cancer types in a large nationwide screening project for solid tumors. Among the 2,180 patients with advanced solid tumors enrolled in the SCRUM-Japan MONSTAR-SCREEN project between October 2019 and September 2021, our analysis of the gut microbiome revealed significant insights into its landscape and its potential impact on ICI efficacy.