Comprehesive DNA methylation profiling reveals novel biomarkers and potential pathways in epithelial ovarian cancer.
This study showed that MeDIP-seq could be used for methylation profiling in an efficient manner and identified a number of potential hub genes and pathways important in the ovarian cancer carcinogenesis that may deepen our understanding of the molecular mechanisms involved inthe development of ovarian cancer. Overall design: DNA methylation profiling of 3 normal, 1 benign and 4 ovarian cancer samples.