RNA-seq of ESCC Cells  Overexpressed TFAP2ß or its LLPS-deficient Mutants
This dataset contains raw RNA-seq data from esophageal squamous cell carcinoma (ESCC) cells overexpressing GFP-TFAP2ß, its LLPS-deficient mutants (?IDR3 and Mut_IDR3) or GFP control. The experiment aims to explore the downstream genes of TFAP2ß and its phase separation-deficient mutants to uncover the role of TFAP2ß's LLPS activity in regulating gene expression in ESCC. Data were collected from the genomic binding of TFAP2ß and its LLPS-deficient mutants, providing insights into the regulatory networks controlled by TFAP2ß in cancer progression. Overall design: RNA-seq of TFAP2ß, its LLPS-deficient mutants (?IDR3 and Mut_IDR3) or GFP control in ESCC cells KYSE150 to understand the downstream genes and regulatory activity associated with TFAP2ß's phase separation mechanism.