Loss of LAPTM4A inhibits M2 polarization of tumor-associated 1 macrophages in glioblastoma, promoting immune activation and 2 enhancing anti-PD1 therapy
Glioma, a highly invasive central nervous system tumor, currently lacks effective 27treatments. This study examines the impact of LAPTM4A deficiency on M2 polarization of 28tumor-associated macrophages (TAMs) and anti-tumor immunity in glioma