Remodelling of the immune landscape by IFN? counteracts IFN?-dependent tumour escape in mouse tumour models
IFN?-dependent remodelling of the myeloid immune landscape underlies control of IFN?-insensitive tumors Overall design: C57Bl6 WT mice were engrafted with the melanoma cell line B16 expressing OVA. CD45+ T cells were isolated by Fluorescence-activated cell sorting (FACS) from the tumor after 12 days and subjected to scRNA sequencing