Gene expression profile at single cell level of mouse cortical brain cells
We used single cell RNA sequencing (scRNA-seq) to compare cortical brain cells from mast cell wild-type with mast cell knockout mice. Overall design: Total cotical brain cells of 8-month-old 5XFAD.Cpa3+/+ and 5XFAD.Cpa3Cre/+ mice were isolated by enzymatic digestion and analyzed using scRNA-Seq.