H3K27ac Hi-ChIP analysis in TAL1-FKBP12 Jurkat cells
H3K27ac Hi-ChIP analysis was performed in TAL1-FKBP12 Jurkat cells to analyze active chromatin-chromatin interactions after DMSO or dTAG-13 treatment. Overall design: The cells were crosslinked with formaldehyde for 10 min.  DNA was enriched by chromatin-immunoprecipitation (ChIP), tagmented with Tn5, subjected for library construction, and sequenced by the DNBseq platform.  Hi-ChIP was performed using an antibody against H3K27ac (Abcam: ab4729).