Effect of resistant secretome on immune cells
In order to study how chemoresistance in breast cancer cells influences immune cells, MDA-MB-468 cells resistant to paclitaxel were generated. Bulk RNAseq were used to assess resistant associated changes. Overall design: MDA-MB-468-PR, was established in-house by exposing MDA-MB-468 cells to paclitaxel (3-4.5nM) for 2 months.