Changes of intestinal flora in rats after copper intervention
27 female Wistar rats (21 days old) were evenly divided into a control group, a low-dose group, and a high-dose group (0, 1, and 4mg/kg • BW Cu2+ solution, respectively) based on similar body weight after one week of adaptive feeding, with 9 animals in each group. The Cu-containing solution was intragastrically administrated to rats at each group for 6 weeks. After the intervention, the fecal samples of all rats were promptly collected for the detection of gut microbiota levels.