Synbiotic Supplementation Modulates Humoral Immunity and Cecal Microbiota in Broiler Chickens Exposed to Subclinical Doses of Fumonisins and Deoxynivalenol
This study investigates the effects of dietary synbiotic supplementation on humoral immune responses and cecal microbiota composition in broiler chickens exposed to subclinical levels of fumonisins (FUM) and deoxynivalenol (DON). Broiler chickens were assigned to four dietary treatments in a 2x2 factorial design: control diet, mycotoxin contaminated diet, synbiotic supplemented diet, and mycotoxin contaminated diet with synbiotic supplementation. Cecal samples were collected to evaluate microbial community composition using 16S rRNA gene sequencing. The objective of this study was to determine whether synbiotic supplementation can mitigate mycotoxin induced alterations in gut microbiota and immune responses in broiler chickens.