Single cell RNA seq of intestinal immune cells and PBMCs in salt-sensitive hypertension
We perfomred sc RNA seq of intetinal immun cell and PBMCs to figure out the roles of intestine in development of salt-sensitive hypertension. We fed a high salt diet(4% NaCl) or a normal salt diet(0.2% NaCl) to Dahl-salt senstive rats for 4 weeks. We isolated immune cells from small instesinal lamin propria and blood. Overall design: we feed high salt diet and normal salt diet to dahl salt sensitive rats for 4 weeks and we then islolated immune cells in small intestine lamina propria and PBMCs