Streptomyces tirandamycinicus strain:MMCC30 Genome sequencing and assembly
The whole-genome and metabolomic analyses of Streptomyces tirandamycinicus MMCC30, isolated from Arabian Sea sediment, revealed 38 biosynthetic gene clusters (BGCs), including 22 with low similarity to known clusters. Metabolomic profiling using HPLC-DAD-MS and GNPS molecular networking suggested the presence of novel anthracycline-like compounds. The crude extract showed cytotoxic activity against NCI-H460 lung cancer cells and antimicrobial effects against various pathogens, highlighting its potential as a source of new bioactive metabolites.