Bio-psychological factors in inflammatory bowel diseases (LIMBO study)
Study of the aetiology and disease activity of the IBDs- as complex and multi factorial chronic disorders- requires examining the intricate interplay between the contributing elements as a measurable network effect to discriminate controlling factors from outcome features. One mechanism for exploring these complexities requires an unbiased and longitudinal data collection and integration strategy which isolates central drivers for inflammation and identifies the hubs that control the disease. This study examines longitudinal bio-psychological dynamics and their interplay, trajectories in UC and CD patients as well as their position/s differences in patients undergoing conventional and biological therapies.