Mouse lung tissue RNA-Seq from C57Bl6 wild type and ALOX15 KO mice with and without house dust mite (HDM) exposure.
Purpose: Identify genes disregulated in wild type C57Bl6 mouse lung tissue in the house dust mite (HDM) asthma disease model and genes differentially expressed in ALOX15 KO mice. Overall design: C57Bl6 mice were challenged daily for 14 days with intranasal house dust mite (HDM) extract.  The HDM challenged mouse lung RNA-Seq from wild type mice was compared to RNA-Seq from lungs of ALOX15 knock out mice.