The effects of Escherichia coli Nissle 1917-derived outer membrane vesicles on the brain of Alzheimer's disease mouse model
To elucidate the downstream molecular mechanisms underlying the Escherichia coli Nissle 1917 (EcN) outer membrane vesicles (OMVs) on Alzheimer's disease pathology, we isolated RNA from the hippocampus tissues of EcN OMVs-treated APP/PS1 mice and control mice, and then performed transcriptomics.