Gene expression profile of bone marrow cells from Ogfrl1 deficient mouse at single cell level
Human data demonstrates loss of function mutations of OGFRL1 are a cause of autosomal recessive forms of cherubism. However, the gene function of OGFRL1 is unknown. We performed scRNAseq to investigate the gene function in bone marrow cells. Overall design: Bone marrow cells were isolated from Ogfrl1 deficient and lettermate control mice.