Epigenomic profiling of SETX and Rloops in meiotic germ cells by CUT&Tag
SETX is a DNA/RNA helicase that resolves R-loop, and lack of SETX in germ cells causes meiotic arrest. To investigate roles of SETX in transcription during meiosis, we perfomred CUT&Tag of SETX and R-loops using antibodies against them. Overall design: CUT&Tag for SETX and R-loop in pachytene spermatocytes.