A mixture of Lactobacilli and Bifidobacteria alleviates  hyperuricemia-induced renal injury via restoring gut microbiota and metabolism.
To create a CKD model, mice with unilateral nephrectomies were employed. Following four weeks of feeding with adenine plus potassium oxacinate, probiotic intervention was administered. Changes in gut microbiota and metabolites can be revealed using fecal microbial 16SrRNA gene sequencing and untargeted metabolomics.