HIIT promotes cardiac recovery after MI in mice
This project used a mouse model of permanent coronary ligation to examine whether a short-bout, low-volume HIIT regimen could improve exercise capacity and LV function after MI. We also sought to investigate the mechanisms underlying HIIT by quantifying cardiomyocyte DNA synthesis as an index of cell-cycle activity and by performing bulk RNA sequencing to profile gene expression changes associated with reduced adverse remodeling.