Effect of specific G-quadruplex stabilization on gene expression and chromatin accessibility at gene promoters in Hela cells.
To investigate specific G-quadruplex stabilization in the regulation of gene expression and chromatin accessibility, we established HeLa cell lines in which each target g-quadruplexes has been stabilized. Overall design: Comparative gene expression and chromatin accessibility profiling analysis of RNA-seq and ATAC-seq data for HeLa cells in which each target g-quadruplexes has been stabilized.