Single-cell RNA sequencing of SCLC tumors with or without XPO1 inhibitor (PRJCA045804)
This project aims to investigate the neuroendocrine phenotype transition and immune microenvironment of small cell lung cancer. A total of 6 tumor samples, including 3 controls and 3 XPO1 inhibitor-treated samples, were collected and profiled with the 10x Genomics single-cell RNA sequencing platform. The dataset provides a resource for understanding cellular plasticity and tumor-immune interactions in small cell lung cancer.