Shear Stress and NOTCH1 Regulate Calcification Related Genes in Human Aortic Valve Endothelium (ChIP-Seq)
We are interested in the role of NOTCH1 and Shear Stress in Aortic Valve Endothelium. Overall design: Primary aortic valve endothelial cells were infected with NOTCH1 intracellular domain fused with a myc tag in order to perform ChIP-seq.