The effect of 10-oxoSA on changes in gene expression
The study aims to investigate how 10-oxo stearic acid (10-oxoSA), a microbial metabolite derived from oleic acid, influences gene expression in the context of metabolic and inflammatory diseases. By focusing on the interaction between 10-oxoSA and the intestinal peroxisome proliferator-activated receptor alpha, the research seeks to understand how this interaction affects gene expression and cellular function. The relevance of this study lies in its potential to uncover novel insights into the role of microbial metabolites in regulating gene expression and their impact on disease processes. Understanding these mechanisms could lead to the development of new therapeutic strategies that target specific microbial metabolites or their pathways, ultimately improving treatment options for metabolic and inflammatory disorders.