Whole genome sequencing of vancomycin-resistant Klebsiella pneumoniae isolate
This project focuses on the whole genome sequencing and comparative genomic analysis of a multidrug-resistant Klebsiella pneumoniae strain (GSFCU1683) with vancomycin resistance and diverse antimicrobial resistance genes. The study aims to identify and characterize resistance-associated genetic elements including vancomycin resistance mechanisms and beta-lactamase genes. Results will provide insights into the molecular basis of antimicrobial resistance and mechanisms of horizontal gene transfer in clinically relevant Gram-negative pathogens.