Comparison of the RB loss-induced transcrptiome in hormone-therapy sensitive and castration-resistant prostate cancer [RNA-seq]
These studies examine the biological networks altered after RB loss across prostate cancer progression. Overall design: Transcriptome alterations in resposne to RB loss after AR stimulation were assessed in early (LNCaP-shCon and LNCaP-shRB) and late (C42-shCon and C42-shRB) stage disease models