Suppression of APAP-induced hepatotoxicity using Slit2
APAP-induced hepatotoxicity can be suppressed by treating Slit2 Overall design: Mice were divided into four groups: Control (PBS only), SLIT2 (SLIT2 only, 2 µg/mouse, intraperitoneally for 3 days), APAP (PBS + APAP, 400 mg/kg), and Double (SLIT2 + APAP). Mice were sacrificed 24 hours post-APAP administration.