RNA-seq in SCLC transformation
SCLC transformation is one of the mechanisms of TKI resistance in lung cancer. To clarify its epigenetic changes, we used RNA-seq to detect the changes of genes in pre-LUAD and post-SCLC transformation cells. Overall design: To detect the changes of genes in pre-LUAD NCI-H1650 cells and post-SCLC transformation NCI-H1650Re cells