Key gut microbe Akkermansia muciniphila improved liver copper removing efficacy in treatment of WD model mice using DPA
Akkermansia muciniphila (Akk) supplementation enhanced the tissue copper removing efficacy of DPA, and was more conducive to the recovery of liver injury, liver dysfunction and gut dysbiosis in WD mice. The the present study provides an experimental basis for the potential applications of targeted regulation of gut microbiota in the adjuvant treatment of copper dysregulation disease.