Heterogeneous Cardiac- and Neural Crest-Derived Aortic Smooth Muscle Cells have Similar Transcriptional Changes after TGFß Signaling Disruption [scRNA-seq-of-Nkx2-5-Cre-mTmG]
We report single-cell RNA-seq data of Nkx2-5 lineage marked, integrin alpha 8 labeled smooth muscle cells (SMCs) from murine aortas at 12 weeks of age Overall design: Root/Ascending/Arch/Descending aortic segments were procured from 12-week-old  Nkx2-5-Cre.mT/mG mice, ITGA8+ SMCs were isolated after cryophilic enzyme digestion, and single-cell RNA-seq analysis was performed