Metagenomic analysis of microalgal-bacterial aerobic granular sludge exposed to antibiotics
Microalgal-bacterial aerobic granular sludge (MB-AGS) reactors were exposed to tetracycline and ciprofloxacin to assess the effects of antibiotic stress on wastewater treatment microbiomes. Metagenomic sequencing was used to investigate shifts in microbial community composition, nitrification- and denitrification-related microorganisms, extracellular polymeric substances, and antibiotic resistance genes under long-term antibiotic exposure.