CPSF6 regulates alternative polydenylation and proliferation of cancer cell through phase separation ?
To verify the effect of phosphorylation of CPSF6 by CLK2 on APA, we co overexpressed CLK2 and wild-type CPSF6 or phosphorylated mutant CPSF6 in HEK293T cells Overall design: Compare the changes in APA length between IVT-SAPAS groups