Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer's Disease by Activated Protein C (APC)
Activated Protein C is an anti-inflammatory with proven treatment of cardiac and neurological disorders. We studied the transcriptional effects of APC on Alzheimers Disease transgenic mice. Overall design: Daily i.p. injection of exogenous APC in WT and 5xFAD mice for 5 months. Daily saline injection were given as controls to WT and 5xFAD mice.