Genetic Profiling of Inherited Colorectal Cancer Syndromes in Tunisian Patients
A cohort of 30 Tunisian patients was selected and divided into two groups based on clinical features and family history: patients clinically diagnosed with hereditary polyposis syndromes, including MUTYH-Associated Polyposis and Familial Adenomatous Polyposis and patients clinically diagnosed with non-polyposis syndromes, including Lynch Syndrome and other rare syndromes. Genetic testing was performed using either Sanger sequencing (15 patients) or targeted next-generation sequencing (NGS) with a cancer panel (15 patients).