Genome wide association analysis in a mouse advanced intercross line
The LG/J x SM/J advanced intercross line of mice (LG x SM AIL) is a multigenerational outbred population. High minor allele frequencies, a simple genetic background, and the fully sequenced LG and SM genomes make it a powerful population for genome-wide association studies. This Bioproject contains DNA sequences from 1,057 AIL mice that we used for Genome-Wide Association Study. It also contains RNA sequences from mouse brain (206 hippocampus, 185 prefrontal cortex, 168 striatum) that we used to find cis- and trans-eQTLs.This dataset has been published in the manuscript: Gonzales NM, Seo J, Hernandez Cordero AI, St Pierre CL, Gregory JS, Distler MG, Abney M, Canzar S, Lionikas A, Palmer AA. Genome wide association analysis in a mouse advanced intercross line. Nat Commun. 2018 Dec 4;9(1):5162. doi: 10.1038/s41467-018-07642-8. PMID: 30514929; PMCID: PMC6279738.