RNA-seq and ChIP-seq data associated with the nuclear hormone receptor transcription factor Mi-nhr-118 of Meloidogyne incognita WHF4-1
To investigate the molecular mechanisms by which 6mA regulates nematode parasitism and development, we used comparative transcriptomics to identify the key regulatory factor Mi-nhr-118. Through comprehensive functional analyses, including RNAi, RNA-seq, and ChIP-seq, we further characterized its downstream target genes. Finally, host-induced gene silencing (HIGS) was used to validate the functions of these targets, demonstrating that Mi-nhr-118 is a critical component of the 6mA-mediated regulatory pathway governing the parasitism and development of root-knot nematodes.