Single-cell RNA sequencing of kidney from idiopathic membranous nephropathy patients
We characterized the renal parenchymal cell and immune cell profiles of IMN renal tissues and discovered the distinct expression signatures of myeloid cell, T cell and B cell subsets. Overall design: In order to explore the molecular mechanism of IMN, we collected renal tissue samples from 3 IMN patients and 1 healthy controls and performed analysis by single-cell RNA sequencing.