Human fetal and pediatric primary gastric samples and organoids derived from them
Reliable modelling of human stomach development and in vitro derivation of mature subsets of gastric epithelial cells has been challenging to achieve in 3D cultures. We derived fetal gastric organoid cultures from 8-20 post-conception week (PCW) stomachs, and post-natal controls from pediatric biopsies. Overall design: mRNA profiles of human primary gastric tissues and cultured organoid derived from fetal and pediatric gastric tissues of different stages.