Mediator Med23 regulates adult hippocampal neurogenesis
we provide evidence that Med23 is involved in the regulation of adult hippocampal neurogenesis in mouse. Med23-deficient NSCs in the SGZ display faster self-renewal activity possibly by reducing cell cycle length, but neuroblasts, immature  and mature new-born neurons are reduced. Overall design: Comparison of mRNA expression profile of between primary NSCs  from the hippocampus of 2-month-old Med23 CKO and littermate control mice.