ChIP-seq for TCF4 in human medial ganglionic eminence-like organoids (hMGEOs) derived from ihtc-03 cell line.
To depict the gene regulatory network of TCF4 in interneuron development, We performed chromatin immunoprecipitation-sequencing (ChIP seq) on human medial ganglionic eminence-like organoids (hMGEOs) to identify genome-wide TCF4 binding sites. This study provides compelling evidence to support the biological rationale linking TCF4 to the developing cortical interneuron. Overall design: Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for TCF4 in hMGEOs derived from ihtc-03 cell line. we identify genome-wide TCF4 binding sites in hMGEOs against the input.