Sigma-1 Receptors Control Neuropathic Pain and Peripheral Neuroinflammation After Nerve Injury in Female Mice: A Transcriptomic Study
To investigate transcriptional changes in the DRG and dorsal spinal cord in wild-type and sigma-1 knockout mice in a well-established model of neuropathic pain (Spared Nerve Injury) Overall design: Comparative gene expression profiling analysis of RNA-seq data for DRG and dorsal spinal cord from wild-type and sigma-1 knockout mice under naive conditions or after spared nerve injury