TCR signaling induces STAT3 phosphorylation to promote TH17 cell differentiation
To systematically evaluate the effect of inhibition of Lck/Fyn kinase activity on the differentiation of TH17 and Treg cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for TH17 (with DMSO/Srci1 or STAT3 KO) and Treg(with DMSO/Srci1) cells.