mNGS revealing benacoxsome
Coxiella burnetii bacteria was found in the blood macrogenome second generation sequencing (mNGS) (high sensitivity whole blood test)  (sequence number 134, positive reference range 1).  The diagnosis of Q fever-(query fever) induced infective endocarditis was considered certain after receiving this new information. Intraoperative aortic valve tissue specimens were taken for mNGS (DNA pathogen detection) and were positive for Coxsackie Baker (sequence number 214080, positive reference range =1).