effects of depeltion of Tim-4 on gene expression in Peritoneal macrophages (PEMs)
T-cell immunoglobulin domain and mucin domain 4 (Tim-4) is known to suppress macrophage inflammatory responses in various diseases, but its role and underlying mechanism in peritoneal macrophage with LPS stimulation are unknown. Overall design: Primary macrophage Peritoneal macrophages (PEMs) isolation from  Tim-4fl/fl mice and LysM-Cre; Tim-4fl/fl mice