Peripheral blood mononuclear cell DNA methylation signatures guide surgical decision-making in indeterminate pulmonary nodules
Genome wide DNA methylation profiling of peripheral blood mononuclear cells (PBMCs) in benign pulmonary nodules (BPN) and early invasive adenocarcinoma (eLC)samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 3,200,000 CpGs in PBMC samples. Samples included 20 eLC patients and 12 BPN controls.