Accessing to additional diversity in Mycobacterium tuberculosis through long-read sequencing: Impact on redefinition of transmission clusters
This study aims to precisely evaluate the impact of long-read sequencing in redefining long-term transmission clusters of M. tuberculosis, previously characterized by short read sequencing. These clusters provide a unique opportunity to assess whether long-read sequencing can contribute to the identification of additional SNPs and refine the understanding of transmission dynamics by increasing the proportion of genome that can be explored.