Whole-exome sequencing of biliary papillary neoplasms and associated invasive carcinoma
This study was designed to analyze 166 intraductal papillary neoplasms of bile ducts and intracholecystic papillary neoplasms, including matched nontumor samples and 41 associated carcinomas, via whole-exome sequencing to uncover genomic signatures in the progression to biliary tract cancer.