Salivary microRNA in children with autism spectrum disorder
Children with autism spectrum disorder (ASD) often face delayed diagnosis and increased oral health problems, such as cavities and gum disease, yet the biological links remain unclear. This study explored whether salivary microRNAs (small molecules that regulate gene expression) could help detect ASD and explain its oral health impacts. By analyzing saliva from ASD and control children, researchers identified miRNAs tied to brain development and known autism-related genes, as well as overlaps with other neurological and systemic conditions. Some microRNAs were also linked to higher rates of dental disease in children with ASD. These findings highlight the potential of salivary microRNAs as noninvasive markers for earlier ASD detection and improved understanding of related health challenges.