Ribo-seq of quadriceps muscle tissues from 10 months old, 30 months old, 30 months old calorie restricted, 30 months old rapamycin treated adult mice
We carried out ribosome footprinting on the Quadriceps femoris muscle of 10 months old, 30 months old, 30 months old calorie restricted, 30 months old rapamycin treated. The treatments were started at the age of 15 months. The main goal of the study was to decipher the translation changes in wild-type aging and upon above mentioned anti-aging treatments. We further investigated non-canonical targets of translational control and identify novel translational units.