Lactobacillus rhamnosus Suppresses Oseoclastogenesis via TLR6/NF-kB Modulation and Attenuates Ovariectomy-Induced Bone Loss in Mice
Osteoporosis is characterized by decreased bone mass and disrupted microarchitecture.Gut microbiota-derived factors may regulate bone homeostasis. This study investigated the effects and mechanisms of Lactobacillus rhamnosus GG-conditioned medium(LCM) on osteoclastogenesis and bone loss.