cancer metagenome
The RNA-seq data presented here were generated to investigate the regulatory role of Far Upstream Element Binding Protein 3 (FUBP3) in gene expression and alternative splicing in cancer cells. FUBP3 is a DNA- and RNA-binding protein that has been implicated in various human cancers, but its genome-wide impact on transcriptional and post-transcriptional regulation remains incompletely understood. By comparing control and FUBP3-knockdown HeLa and Huh7 cells, this dataset enables the identification of differentially expressed genes and alternative splicing events associated with cell proliferation, apoptosis, and cell adhesion. These data provide a valuable resource for understanding how FUBP3 contributes to cancer cell biology and may reveal novel targets for cancer diagnosis and therapy.