Transcriptomic analysis of engineered myometrial tissues with varied tissue architecture and matrix rigidity
We report the use of RNA-seq for transcriptional analysis of engineered myometrial tissues cultured on hydrogels with varied matrix rigidity and tissue alignment. Overall design: mRNA profiles of engineered myometrial tissues on representative healthy (13 kPa - aligned) and fibrotic (90 kPa - isotropic) substrates