How useful is Nanopore adaptive sampling for sequencing Schistosoma mansoni miracidia?
In this study, we evaluated the potential of Nanopore adaptive sampling to selectively enrich Schistosoma mansoni DNA from both washed and unwashed larval stage miracidia. We used Kraken2 to characterise sample contamination and assessed sequencing breadth and depth of genome coverage to determine whether adaptive sampling could provide sufficient S. mansoni DNA for WGS.