Expression profiles of SMMC-7721 cells after P5CS knockdown
P5CS catalyzes the synthesis of pyrroline-5-carboxylate (P5C), a key precursor for the synthesis of proline and ornithine. Recently, it has been reported that loss of P5CS leads to multiple metabolic defects due to defects in mitochondrial respiration. Then, we performed high-throughput transcriptome sequencing (RNA-seq) and obtained the transcriptome expression profiles of SMMC7721-shP5CS cells and control cells.