Efferct of Vista deficiency on mucosal damage in DSS-induced colitis
To investigate the effect of Vista, a novel immune checkpoint, on intestinal damage of DSS(dextran sulfate sodium)-induced colitis mice. Overall design: Vista-/- and WT mice were orally administrated with 2% DSS in drinking water for the induction of colitis and subsequently the colons were collected respectively. Three biological replicates were performed for RNA-sequencing in each group.