Mechanisms for more efficient antibiotics and antibiotic resistance genes removal during industrialized treatment of over 200 tons of tylosin and spectinomycin mycelial dregs by integrated meta-omics
To minimize the dissemination of ARGs caused by the accumulation of antibiotic mycelial dregs (AMDs), this study first attempted over two hundred tons of mass production fermentation (MP) with tylosin and spectinomycin mycelial dregs and employed pilot-scale fermentation (PS) as a comparison group utilizing the integrated-omics.