identification of the NagY regulon of Enterococcus faecalis
Enterococcus faecalis is responsible for health-related pathologies. Under conditions of infection, the N-acetylglucosamine metabolism of E. faecalis undergoes significant changes in expression, even more important than those of virulence factors. This metabolism is mediated by the transcriptional antiterminator NagY. RNA-Seq approach was used to identify the regulon of this regulator and its impact on bacterial metabolism. This study provides a valuable advance in the understanding of regulation and the importance of post-transcriptional actors in E. faecalis adaptation.