SRCAP Mutations Drive Clonal Hematopoiesis Through Epigenetic and DNA Repair Dysregulation [scRNA-Seq]
To investigate the transcriptomic regulation of Srcap mutant lymphoid-biased expansion after compeititve transplantation Overall design: We established Srcap heterozygous mutant murine competitive transplantation model.  Donor test (CD45.2+) HSPCs in the bone marrow were sored and isolated at 20 weeks post-transplantation for scRNA-seq