Analysis of dynamic distribution of RAD51/DMC1 in homologous recombination
RAD51 and its meiosis-specific homolog DMC1 are evolutionarily conserved recombinases that play pivotal roles in homologous recombination. To understand their localization dynamics on chromatin, we performed ChIP-seq for both RAD51 and DMC1 in meiotic cells in budding yeast and mice, and proliferating somatic cells in mouse embryonic fibroblasts.