Epigenetic changes underlying mouse hematopoietic stem cell aging
We investigate the aging changes for Histone marks H3K4me3, H3K27me3 and H3K36me3 for mouse hematopoietic stem cells. Overall design: Mouse hematopoietic stem cell histone methylation profiles of 4 month and 24month old WT mice were generated generated by deep sequencing, in duplicate, using Illumina Hiseq 2000