Administration of AGNHW enhances neurogenesis and angiogenesis in a mouse model of experimental cerebral ischemia injury
To explore the internal mechanism of AGNHW therapeutic effects on stroke mice, we performed RNA sequencing (RNA-seq) analysis in MCAO mice. The results showed that AGNHW changed the gene expression profile in the brain of stroke mice after administration Overall design: TRIzol reagent was used to extract RNA from the brains of mice in sham, vehicle and AGNHW group. RNA quality was determined by Agilent 2100 Bioanalyzer. Illumina HiSeq 2500 platform was used for high-throughput sequencing by Anuolu Company in Beijing.