Improving Diagnostics for Osteomyelitis Associated with Orthopedic Trauma: Identifying Sessile Microorganisms Adhered to Implants
Implant-related infections are difficult to diagnose due to false negatives from traditional methods, especially in cases of prior antibiotic use and biofilm concentration. S. epidermidis is commonly isolated, but Brazilian studies are lacking. Biofilm interferes with treatment, requiring new diagnostic methods to identify sessile microorganisms and their virulence and resistance factors. The study's impact is significant in providing specific diagnoses, successful therapy, and reduced expenses.