Effect of Escherichia coli B2 on gene expression before and after citric acid-induced antibiotic tolerance
In order to explore the differentially expressed genes of E. coli B2 after citric acid induced antibiotic tolerance, we artificially induced the antibiotic tolerance of E. coli O157: H7 and verified its phenotype. Overall design: In vitro, citric acid was added during bacterial culture to artificially induce antibiotic tolerance of E.coli B2 bacteria.