Modeling Atrial Fibrillation (AF) in a Dish using Atrial iPSC-Derived Cardiomyocytes (iPSC-CMs)
Our study aims to illustrate the potential use of atrial iPSC-CMs for modeling AF in a dish, elucidating the underlying cellular mechanisms, and identifying novel mechanism-based therapies custom-tailored for individual patients Overall design: We have 3 cell lines: Mutant A, Control A, Genomic-edit A. Each cell line has 2 samples, we plan to compare RNA-seq results in three cell lines