Pharmabiome of simulated falsified medical tablets
Raw sequences corresponding to publication titled Pharmabiome in tandem with chemometrics can help trace the provenance of falsified medicines, a proof of concept study. In this study we tested the feasibility of geolocating the production sites of falsified medicines, based on the identification of site specific biological and chemoisotopic features using a combination of environmental DNA metabarcoding, Direct Analysis in Real Time mass spectrometry and Isotope Ratio mass spectrometry as profiling techniques. We produced tablets at two distant locations, UK vs. Thailand, using controlled manufacturing methods and excipient composition, under different environmental conditions. The sequences deposited here correspond to the DNA sequencing of the produced tablets, for profiling of the bacterial, 16S, and the eukaryotic, 18S, communities within the tablets.