Gene expression profile of TPT1  gene knock downed  human ES-NSC
To evaluate the function of TPT1 in human ES-derived neural stem cells (ES-NSCs), we knock downed TPT1 gene expression based on the lentivirus system expressing shTPT1 RNA with control. We isolated RNA from ES-NSCs 2 days after infection and subjected to RNA-seq analysis. In silico data analysis supported the function of TPT1 related to cell cycle regulation, consistent with in vitro experimental results. Overall design: Examination of gene expression profile of  TPT1  gene knock downed  human ES-NSC