RNA-seq of Raji cells expressing either IL-13Ra1 or IL-13Ra1-LOR1a and treated with IL-13 or not
Raji cells were transduced to express either that canonical IL-13Ra1 subunit of the shared type II receptor for IL-4 and IL-13 or a newly discovered, termed IL-13Ra1-LOR1a. These cells were treated with IL-13 and compared with untreated control cells, as well as with treated and untreated untransduced Raji cells, with the aim of assessing the potential of the IL-13Ra1-LOR1a isoform to transmit IL-13 signals. Each condition was tested in triplicate.