Alterations of Gut-Derived Melatonin in  Neurobehavioral Impairments Caused by Zinc  Oxide Nanoparticles
The widespread use of zinc oxide nanoparticles (ZnONPs) has raised concerns about its potential toxicity. Melatonin isa neurohormone with tremendous anti-toxic effects. The enterochromaffin cells are an essential source of melatonin in vivo. However,studies on the effects of ZnONPs on endogenous melatonin are minimal. In the present study, we aimed to investigate the effects ofZnONPs exposure on gut-derived melatonin