Predisposal of Interferon Regulatory Factor 1 Deficiency to Accumulate DNA Damage and Promote Osteoarthritis Development in Cartilage [Ad_RNA-seq]
To investigate the function of IRF1 in chondrocytes, we performed transcriptome analysis in priamry mouse articular chondrocytes. Using adenovirus expressing mouse Irf1 (Ad-Irf1) or expressing eGFP (Ad-eGFP), Irf1 was overexpressed in mouse chondrocytes. Overall design: RNA sequencing data using samples from Ad-Irf1 or Ad-eGFP infected primary mouse articular chodnorcytes