The multifaceted impact of dexamethasone on human osteogenic differentiation is reflected in dysregulated ossification and inflammatory cytokine pathways.
This study investigates the effects of dexamethasone on human bone marrow mesenchymal stromal cells (BMSCs) during osteogenic differentiation using RNA sequencing with Oxford Nanopore Technologies (ONT). Differential gene expression analysis was used to highlight the complex role of dexamethasone in bone differentiation and remodeling.