Enhancer-activated RET confers protection against oxidative stress to the MLL-rearranged acute myeloid leukemia cells
RET expression is upregulated in AML subtypes harboring genetic fusions of MLL-1 genes compared to age-matched healthy donors and other AML subtypes. In addition, we identify a novel epigenetic mechanism of RET overexpression in MLL-rearranged AML. Overall design: examination of  chromatin accessibility in CD34 and MOLM13 cells