Unveiling the differential Senescence Phenotypes of MCF7 Cells Treated with Diverse Therapeutic Agents: A Comprehensive Transcriptome Analysis
Therapeutic drugs are commonly used for treatment various cancers. However, despite to this purpose,  Cancer treated by drugs undergoes senescence phenotypes and is known to acquire more aggressive ability. Futhermore, senescence can be induced vairous type of drug via differential mechanisms. Therefore, we analyzed to validate differential charateristics of senescence phenotypes compare between drugs. Overall design: control MCF7, Doxorubicin treated MCF7, Cisplatin treated MCF7 and Palbociclib treated MCF7 were compared