Cell type-intrinsic differences in the host transcriptome of Chlamydia trachomatis-infected primary human endocervical epithelial cells and vaginal epithelial cells [HVE_seq]
To investigate the role of cell type-intrinsic gene expression to fibrotic sequelae of Chlamydia trachomatis (Ct) infection of the upper female genital tract, we compared the transcriptomic response of primary human endocervical epithelial cells (HCECs, see GSE198272) to that in vaginal epithelial cells (HVEs). Overall design: Comparative gene expression profiling analysis of RNA-seq data between Ct serovar L2- and mock-infected endocervical epithelial cells and vaginal epithelial cells.