Macleaya cordata Alkaloids Sanguinarine and Chelerythrine Inhibit Nocardia seriolae by Disrupting Cell Envelope  Integrity and Energy Metabolism: Insights from  Transcriptomic Analysis
Nocardia seriolae infection poses a serious threat to largemouth bass (Micropterus salmoides) aquaculture, owing to the lack of effective control strategies. This study investigated the antibacterial effects and underlying mechanisms of Macleaya cordata alkaloids sanguinarine (SE) and chelerythrine (CHE)against N. seriolae through integrated physiological and transcriptomic approaches.