Phase separation of phospho-HDAC6 drives aberrant chromatin architecture in triple-negative breast cancer [RNA-seq]
To further elucidate the role of phospho-HDAC6 LLPS in transcriptional regulation, we performed RNA-seq experiments in TNBC cells treated with Nexturastat A or HDAC6 knockdown Overall design: Comparative gene expression profiling analysis of RNA-seq data for MDA-MB231 cells with and without HDAC6 inhibitor Nexturastat A treatment. Comparative gene expression profiling analysis of RNA-seq data for MDA-MB231 cells  and its HDAC6 KD derivatives (shHDAC6).