Chromatin accessibility profiling in wild-type naïve, 1h, or 24h in vitro stimulated P14 CD8+ T cells
To investigate the kinetics of chromatin accessibility dynamics in activated CD8+ T cells, we stimulated naïve P14 CD8+ T cells in vitro for 0h, 1h, or 24h We then performed chromatin accessibility profiling analysis by ATAC-seq Overall design: Chromatin accessibility profiling analysis by ATAC-seq for WT P14 CD8+ T cells at 0h (naïve), 1h, or 24h-post stimulation with anti-CD3, anti-CD28, and recombinant IL-2 in vitro