RNA-seq analysis comparing Spry1flox/flox mice back epidermis to the back epidermis derived from Spry1 epidermis specific knockout mice
We found that Spry1 epidermis specific knockout give rise to back epidermis hyperpigmentaiton highly mimicks tanning response in mouse Overall design: Spry1 epidermis specific knockout were induced by tamoxifen treatment. The epidermis were harvested and compared with the Spry1flox/flox mouse back epidermis for RNA-seq analysis