Gene expression profile of supernumerary type II neuroblasts transiently overexpressing Insb
Genes that positively regulate neuroblast functional identity shoud be expressed in type II neuroblasts and become repidly downregulated in immature INPs in wild-type brains while genes that suppress neuroblast functional idnetity should be upregulated in immature INPs. The goal of this study is to identify genes involved in regulation of type II neuroblast functional identity. Overall design: mRNA profiles of brat mutant brain without Insb overexpression (0-hr) and brat mutant brains following 9 and 18 hours of Insb overexpression (9-hr and 18-hr) were generated by deep sequencing, in triplicate