High-throughput sequencing of miRNAs expressed in the rat colon during 24h light dark cycle
Colorectal cancer (CRC) belongs among the most frequent malignancies diagnosed in Europe and USA. As CRC progression is strongly influenced by miRNAs as well as the circadian system, we performed high-throughput sequencing of miRNAs expressed in the rat colon during 24h light (L) dark (D) cycle under synchronized conditions to identify rhythmically expressed miRNAs.