Effect of MetAP2 the inhibitor SDX-7320 on gene expression in BT-474 xenografts
Analysis of gene expression using bulk RNASeq was performed on tumors dissected from vehicle-treated and SDX-7320-treated mice (12 mg/kg). The analysis of RNASeq data showed that a several pathways were modulated in tumors from mice treated with SDX-7320. Overall design: Comparative gene expression profiling of RNA-seq data for BT-474 tumors treated with the MetAP2 inhibitor SDX-7320.