CASTLE panel: Cancer Standards Long-read Evaluation
CASTLE panel is a multi-technology whole-genome sequencing of six commercially available tumor/normal cell line pairs (HCC1954, HCC1937, H1437, H2009, Hs578T and HCC1395). Genomic sequencing currently includes PacBio, Oxord Nanopore, Illumina and PoreC, in most cases sequenced from the same DNA extraction or cell line passage. We generated this panel to motivate benchmarking and development of new short- and long-read tools for cancer genomics. A more detailed description and variant calls benchmarks are available at: https://github.com/CASTLE-Panel/castle