Mapping HIV-1 RNA Structure, Homodimers, and Long-Range Interactions by HiCapR (PRJCA025290)
This project presents a study that investigates the RNA structure of the Human Immunodeficiency Virus (HIV) to better understand its replication and assembly processes. The research introduces HiCapR, an innovative method based on psoralen crosslinking and RNA proximity ligation, which allows for the detection and analysis of long-range and global RNA-RNA interactions within the HIV genome.