Genetic changes of Hep3B cells with acquired resistance to sorafenib after STIM1 knockout
In order to explore the role of STIM1 in the acquired resistance of Hep3B cells to sorafenib, we used CRISPR Cas9 technology to knock out STIM1. Overall design: Comparative gene expression profile analysis of RNA-seq data from wildtype Hep3B SR cells and STIM1 knockout Hep3B SR cells.