Single cell Transcriptome characterization of the effects of exosomes from different sources on testicular tissue of male mice
Collect the blood circulation exosomes from antibiotic treated or wild type mice, and then inject them into the recipient mice through tail vein, collect the testicular tissue of the recipient mice, conduct transcriptome sequencing, and analyze and compare gene expression differences Overall design: Inject PBS (BP), blood exosomes from wild-type mice (BE), and intestinal microbiota imbalance mice (BdE) into the mouse model of azoospermia induced by Baixiaoan.