Transcriptomic differences between radioresistant MDA-MB-468 and parental MDA-MB-468
A radioresistant MDA-MB-468 cell line, a human TNBC cell lines, was developed by giving a total dose of 50Gy (2gyx5, 4Gyx3, 6Gyx3, and 10Gyx1) to the parental cell line. The trancriptomic changes that occur include enhanced antioxidant response, increase in DNA repair pathways, and invasion/metastasis features. Overall design: RNA-seq of MDA-MB-468 radioresistant vs parental cell lines