mRNA expression profiles of engineered chondrocyte sheets
Cartilage injury does not naturally repair and lead to osteoarthritis.  Engineered chondrocyte sheets are readily transplantable and create neocartilage in vivo.  This experiment compares global mRNA profiling of adult and juvenile chondrocyte sheets. Overall design: Examination of mRNA profiles of engineeredchondrocyte sheets created from adult cartilage and juvenile cartilage.