Gene expression changes in HEK293 cells following PEG10 overexpression.
The goal of this study was to determine transcriptional changes in HEK293 cells upon overexpression of various forms of Paternally Expressed Gene 10, or PEG10. Cells were transfected either with control, or with PEG10 gag, gag-pol, or isolated NC fragment constructs and RNA isolated for RNA-Seq analysis. Overall design: Three independent passages of HEK293 cells were transfected with PEG10-expressing constructs (gag-pol, gag, NC) or control (LifeAct).