Detecting microbial engraftment after FMT in patients with ulcerative colitis
This study investigates microbial engraftment in ulcerative colitis (UC) patients who received FMT from a single donor, using both shotgun metagenomics and culture-enriched metagenomics. Shotgun metagenomic sequencing was performed on fecal samples collected from patients in both the FMT and placebo groups at baseline and at the end of the trial.