B cell receptor repertoire sequencing of peyer's patches in humanized IGHA1 and wild-type C57BL/6J mouse (PRJCA019927)
To verify the ability of IGHA1+/+ mice to generate a diverse range of immunoglobulins through variable, diversity, and joining gene (V-D-J) rearrangement, somatic hypermutation (SHM), and class switch recombination (CSR), we conducted B-cell receptor (BCR) sequencing of the terminal ileum tissue with Peyer's patches.