Dry-eye metagenome Raw sequence reads
This project investigates the gut microbiome in adults with dry eye disease and its modulation by microbiome-targeted nutritional interventions. Raw FASTQ files were generated from stool samples collected longitudinally from participants enrolled in a randomized, controlled clinical study evaluating a fixed-content prebiotic formulation. The aim is to identify gut microbial community features associated with dry eye disease, characterize intervention-related changes in taxonomic composition and diversity, and explore associations between gut microbiome profiles and clinical outcomes including tear film stability, tear production, and symptom severity.