RNA-Seq result of Bulk spinal cord of SOD1*G93A transgenic mice treated with PF-04457845 or vehicle
SOD1*G93A transgenic mice were treated with PF-04457845 (a FAAH inhibitor)or vehicle . PF-04457845 extended survival of SOD1*G93A transgenic mice and resucued loss of motor neurons. Overall design: SOD1*G93A transgenic mice were treated with PD-04457845(1mg/kg/day) or vehicle by chow from age of week 8 until endpoint