Chromatin immunoprecipitation sequencing to identify KDM4A regulating signaling pathway in CRC
To explore the underlying mechanism of KDM4A mediated H3K9me3 modification in CRC. We performed Chromatin immunoprecipitation sequencing(CHIP-seq) between control CRC cells and CRC cells with KDM4A overexpression to identify KDM4A regulating signaling pathway. Overall design: CHIP-seq profiling of control group and KDM4A overexpression group using HCT8 cells