Crotonis Fructus induced gut microbiota disorders in rats
Crotonis Fructus (CF), a poisonous traditional laxative, has been used to treat constipation, edema, ascites, and inflammation for more than two thousand years. However, CF possesses toxicity and its toxic mechanism is still unclear. Thus, High-throughput sequencing was employed on the 16S rDNA gene to explore the intestinal flora.