Improved Efficacy of Fecal Microbiota Transplantation for Ulcerative Colitis with Non-urbanized Donors
We performed metagenomic and transcriptomic sequencing to analyze the complex intestinal microbial communities in fecal and intestinal mucosal samples from germ-free mice with DSS-induced inflammatory bowel disease (IBD) treated with fecal microbiota transplantation (FMT), aiming to investigate the dynamics of the intestinal microbiota during FMT therapy.