Effect of deletion of PKM on gene expression in dental epithelium during tooth development
To elucidate the role of pyruvate kinase M (PKM) in tooth development, we conditionally deleted PKM in dental epithelium of mice. We then collected dental epithelium from control and knockout groups at postnatal day 0 to conduct gene expression profiling. Overall design: RNA-seq profiling of wildtype dental epithelial cells and Pkm cKO groups at postnatal day 0 from mouse model