Gut microbiota profiles in feces and paired tumor and non-tumor tissues from Colorectal Cancer patients. Relationship to the Body Mass Index.
Colorectal Cancer (CRC) and Obesity constitute two of the most common malignancies in the world. The main aim of this study was to provide molecular data on intestinal microbiota patterns in subjects with CRC, as well as to establish possible associations with their Body Mass Index (BMI). Our results revealed relevant associations between gut microbiota composition and tumor location. Microbiota from obese CRC patients was significantly enriched, among others, in Bacteroidales. These data are useful in the molecular characterization of CRC in obese and non-obese patients.