RNA-seq and CUT&RUN of erythroblasts upon perturbation of gamma-hemoglobin repressors
Through high throughput compound screening, we've identified compounds that induce the expression of fetal hemoglobin. This study contains RNA-seq and CUT&amp;RUN data of a novel target, WIZ. The experiments contain erythroblast data at different differentiation times, where WIZ was perturbed either through a low molecular weight inhibitor that degrades it or by CRISPR-mediated knockdown.