Faecalibacterium prausnitzii abrogates immunotherapy toxicity
To elucidate whether Faecalibacterium prausnitzii has effects on intestinal toxicity induced by immune checkpoint inhibitors, we performed RNA-seq analysis of colon tissues of mice receiving DSS, DSS+ICB and DSS+ICB+F. prausnitzii gavage to compare the gene expression profiles. Overall design: RNA-seq was performed on colon tissues of mice receiving DSS(N=5), DSS+ICB(N=5) and DSS+ICB+F. prausnitzii gavage(N=5)