Transcriptome profiling of WT and BS lymphoblast and fibroblast human cell lines, WT and BLM knock-out mouse ES cells from 129/CAST F1 hybrids
We performed RNA-seq experiments to compare effect of Bloom Syndrome / Blm knock-out on gene expression. The following cell lines were used: GM12982 (human lymphoblasts, WT), GM16375, GM17361 (human lymphoblasts, BS); GM07492, GM07545 (human fibroblasts, WT), GM02085, GM03402 (human fibroblasts, BS), mouse ES cells from F1 cross between strains 129 and CAST: WT and with Blm knocked-out. The experiments were done in triplicates.