Genome wide N-MYC binding in human inv(16) AML cells
To identify the role of N-MYC in transcriptional regulation in human inv(16) AML, we conducted conducted CUT&Tag analysis for N-MYC and H3K27AC in ME-1 cells Overall design: Chromatin was immunoprecipitated with N-Myc, H3K27ac and IgG antibodies. Sequencing was performed on an Illumina NextSeq500 (paired-end).