Tripartite motif 8 promotes hepatocellular carcinogenesis by mediating ubiquitination and degradation of hepatocyte nuclear factor 1a
To explore the underlying mechanism of TRIM8 in HCC, a RNA sequencing was conducted to obtain the differentially expressed genes (DEGs) between TRIM8-KO and WT HepG2 cells Overall design: Comparative gene expression profiling analysis of RNA-seq data for TRIM8-knockout and wild-type HepG2 cells