Effect of depletion of HIF-1a on gene expression during B cell IgA class switching [RNA-seq]
Investigate the function HIF-1a in the regulation of B cell IgA class switching using WT and HIF-1a conditional knockout mice. Overall design: We then performed gene expression profiling analysis using data obtained from RNA-seq of 3 WT and 3 HIF-1a KO samples during B cell IgA class switching.