Transcriptome sequencing data of the Chinese soft-shelled turtle (Pelodiscus sinensis)
Temperature is critical for pathogen-host interactions in ectotherms like the Chinese soft-shelled turtle (Pelodiscus sinensis), a valuable aquaculture species severely affected by Aeromonas hydrophila. This project's transcriptome data supports our finding that temperature governs A. hydrophila pathogenicity via the virulence factor LasB, which mediates pyroptosis in P. sinensis intestinal cells. LasB expression peaks at 35 degrees C, and its knockout reduces bacterial pathogenicity and cell toxicity, offering insights for turtle disease control.