High-throughout sequencing of colorectal cancer and non-small cell lung cancer cells treated actived compound YHM18
The high-throughput sequencing technology was performed after the treatment of human colorectal cancer cells HCT116 and non-small cell lung cancer cells A549 with the active compound YHM18 designed and synthesized by ourselves, to explore the expression of genes related to cell proliferation, adhesion, migration and invasion of human colorectal cancer cells HCT116 and non-small cell lung cancer cells A549 after the treatment of the active compound and to find an interesting target gene, GTSE1. Overall design: Human colorectal cancer cells HCT116 and non-small cell lung cancer cells A549 were treated with active compound YHM18 at the concentration of 2 µM for 48 hours.