Nuclear translocation of PTH receptor hijacks thyroid hormone signaling for bone mass regulation [RNA-seq]
After demonstrating that the bone-forming ability of mice is altered by blocking PTH1R entry into the nucleus, We performed RNA-seq on BMSCs from Pth1r?NLS individuals and wild-type individuals to explore the mechanism behind this phenomenon. Overall design: Comparative gene expression profiling analysis of RNA-seq data for BMSCs solated from heterozygotes and wild-type individuals of Pth1r?NLS mice