HDAC1/2 -mediated repression of Wnt receptors controls polarity orientation in epidermal stem cells in C. elegans.
In this study we employ TargetedDamID  to identify targets within the epidermis for the histone deacetylase HDA-1 that we identified as a key epidermal development regulator. Overall design: Identification of HDA-1 genome-wide binding by epidermis-specific expression of HDA-1:Dam fusion in C. elegans. Samples containing the NLS-GFP:dam fusion only constitute control samples.