The rectal microbiome and incident rectal sexually transmitted infections
The objectives of these analyses were to:1. Assess associations between demographic, clinical and behavioral factors and features of the rectal microbiota as well as 2. Assess associations between features of the rectal microbiota and incident rectal gonorrhea and chlamydia infection and changes in the microbiota with such infections in Nigerian men who have sex with men who did not have a concurrent gonorrhea or chlamydia infection. Archived rectal swab samples used in the analysis were originally collected in the TRUST/RV368 cohort. Participants in the parent cohort were recruited using respondent-driven sampling (RDS). Inclusion criteria for TRUST/RV368 included male sex, a valid RDS coupon, and anal sex with a male partner in the past 12 months.