Single-nucleus RNA-seq of aortas from Ldlr-/- and Ldlr-/-Trem2-/- atherosclerotic mice
Single-nucleus RNA-seq of aortas was performed in Ldlr-/- and Ldlr-/-Trem2-/- mice fed a high fat diet for 10 weeks Overall design: Ldlr-/- (n=3) and Ldlr-/-Trem2-/- (n=3) female mice were fed a high fat diet for 10 weeks to induce the formation of atherosclerotic plaques. Aortas were excised, cryoconserved and nuclei extracted for single-nucleus RNA-sequencing