Deconvolving the transcriptional signature of sexual commitment in Plasmodium falciparum
This dataset aimed to investigate the transcriptional pathways driving the switch from asexual to sexual stage development of Plasmodium falciparum starting from the initial transcriptional response to variation in environmental LysoPC levels. Two culture adapted P. falciparum strains: Pf2004 from West Africa and Dd2 from Southeast Asia were subjected to either mFA (induction medium) or serum supplemented control medium. After 16 and 22 hours of further incubation, respectively, two time points were collected for analysis and samples from both strains pooled per condition.