Assessment of transcriptional ERa activity following exposure to 17a-E2 and 17b-E2
The study shows that, regardless of dose, both estrogens elicit nearly identical ERa activity Overall design: U2OS Cells were transfected with ERa and were exposed to vehicle, 17a-E2 (10nM & 100nM), or 17b-E2 (10nM) for 24 hours in preparation for RNA and ChIP sequencing analyses