Erbb2 establishes the timing of progesterone priming required for uterine receptivity
This project investigates the role of Erbb2 in regulating uterine stromal progesterone responsiveness during the peri-implantation period in mice. Using bulk RNA sequencing of stromal tissues collected on day 4 of pregnancy, we examined transcriptional alterations caused by uterine Erbb2 deletion. The data provide insight into how Erbb2 enables timely progesterone receptor activation, promotes stromal preparedness, and ensures normal implantation and decidualization. These findings contribute to understanding the molecular mechanisms governing uterine receptivity.