Transcriptome sequencing of U251 glioma cells
Gliomas are the most prevalent primary brain tumors with high mortality rates. Long noncoding RNAs (lncRNAs) have emerged as important regulators in cancer progression, especially gliomas. Actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1), a lncRNA plays a key role in cancers. However, its specific role in glioma progression and the underlying mechanisms remain elusive.