Evaluating Prebiotic Activity of Arabinogalactan on the Human Gut Microbiome
This study investigates the prebiotic potential of Arabinogalactan (AG), a dietary polysaccharide, and its influence on the human gut microbiota. By using anaerobic in vitro incubations combined with Raman microspectroscopy and Raman-activated cell sorting (RACS), the research highlights how AG selectively promotes the growth of beneficial and health-associated microbial taxa. Focusing on metabolically active bacteria, the study aims to uncover specific microbial responders to AG and understand its role in supporting gut health. These insights underline AGs promise for developing next-generation prebiotics. Sequencing was performed at the Joint Microbiome Facility of the Medical University of Vienna and the University of Vienna under the project ID JMF-2307-05