Genome sequencing of Hepatitis E virus from an emergency patient in Qingdao for  phylogenetic analysis
This project aims to sequence and analyze the genome of Hepatitis E virus (HEV) detected in a blood sample from an emergency patient in 2025 to investigate evolutionary relationships. Through metagenomic next-generation sequencing (mNGS), we obtained 50 viral reads, which were assembled into sequences compared to genotype 4d. Phylogenetic analysis showed that the sequence cluster most closely with genotype 4d. The data will provide insights into the molecular characteristics and within-host genetic diversity of HEV in clinical settings, contributing to understanding of viral evolution and potential implications for diagnosis, treatment, and public health surveillance. Sequencing was performed using an mNGS platform generating viral genome sequences.