ERK5 sustains autocrine mitogenic balance for cell fate specification in human pluripotent stem cells [ChIP-seq]
To investigate the function ERK5 in the regulation of hPSC histone modification, we processed ERK5 inhibition (XMD892) treamtent in E8 medium for 24hr in H1 ESCs. And H3K27ac and H3K4me3 ChIP-seq test Overall design: We then performed gene expression profiling analysis using data obtained from ChIP-seq of H1 ESCs.