Salvianolic Acid B Attenuates Cellular Senescence and Age-Related Sarcopenia via Dual mTOR/TP53INP2-Autophagy Regulation
Research has demonstrated that SAB effectively alleviates the cellular senescence phenotype. It was observed that SAB reduces SASP expression through modulation of the mTOR pathway. Additionally, SAB was found to decrease cellular ROS levels and enhance ATP production. In vitro studies further revealed that SAB ameliorates age-related sarcopenia, potentially through promoting TP53INP2 expression to enhance autophagy. These findings provide novel insights into the potential applications of SAB in the field of anti-aging research.