Genomic characterization of ESBL-producing Escherichia coli isolates from patients in an orthopaedic ward in Mwanza, Tanzania
This project investigates the genomic characteristics of extended-spectrum beta-lactamase -producing Escherichia coli isolates collected from patients in an orthopaedic ward at a tertiary hospital in Mwanza, Tanzania. Whole genome sequencing was performed using Illumina paired-end sequencing to characterize antimicrobial resistance determinants, plasmid content, virulence factors, and phylogenetic relationships. The data support understanding of the transmission dynamics and genomic epidemiology of multidrug-resistant E. coli in a hospital setting.