LncRNA CARINH regulates expression and function of innate transcription factor IRF1 in macrophages [RNA-Seq]
The antisense lncRNA CARINH acts as an additional regulatory layer of antiviral immunity through coordinated regulation of the transcription factor IRF1 and downstream interferon-stimulated genes. Overall design: We used three replicate samples of BMDM cells from WT mice and Carinh-KO mice. Either group treated with IFN for 8 hours or vehicle.