Effect of Gut Microbiota on Neurodevelopment  Disorder-Associated Behavioral Abnormalities in CLC4 Knockout Mice
Neurodevelopmental disorders (NDDs) are characterized by deficits in the nervous system, with chloride ion channel 4 (CLC4) playing a crucial role. Increasing evidence suggests an association between the gut microbiota and NDD; however, the underlying mechanisms remain unclear. This study examined whether CLCN4 knockout (KO) alters the gut microbiota composition and contributes to NDD-like behaviors in mice.