A RofA-family transcriptional regulator, GadR, controls expression of the glutamate decarboxylase system in Listeria monocytogenes and is required for adaptive acid resistance.
To investigate how Listeria monocytogenes response to mild acid stress and the role of RofA-family regulator GadR in this stress response, RNA seqeuncing experiment was perfromed for strains EGD-e wild type and gadR+ grown to exponential phase with or without exposure to 15 min pH 5 treatment.