Gut microbiota in type 2 diabetics and non-diabetics
A lack of research on gut microbiota in the African continent, particularly concerning Type 2 Diabetes Mellitus (T2DM), has been observed. This study seeks to fill this significant void by undertaking an extensive comparative examination of gut microbiota composition within a South African population. The investigation encompasses both individuals diagnosed with T2DM and those without diabetes. The study design incorporates rigorous methodologies, including high-throughput sequencing techniques to identify microbial signatures and identify potential correlations with the presence of T2DM.The key contributions of this research include the following: 1. Relevance to Microbiology and Human Health: The study addresses the intricate relationship between gut microbiota and human health, specifically exploring the impact of T2DM on the microbial composition. This research is crucial in expanding our understanding of the microbiome's role in metabolic diseases. 2. Clinical Implications: The findings of our study have potential implications for the management and treatment of T2DM. Understanding the specific alterations in the gut microbiota associated with diabetes mellitus can pave the way for targeted interventions and personalized treatment strategies.