Translatome analysis of murine heart in space.
Our study aims to comprehensively understand the effects of translation by the space environment on mammals. To achieve this aim, we analyze the male mice housed under environments as the artificial gravity and the microgravity (space environment) in Japanese Experiment Module JEM) of the International Space Station (ISS) on orbit for 35 days. After recovering these mice on the ground, the ribosome profiling analysis by next-generation sequencing technology is performed about hearts to examine alteration of translation in the space.