Topoisomerase 1 facilitates nucleosome reassembly at stress genes during recovery [Mnase-seq]
Investigate the role of topoisomerase 1 in the response to oxidative stress Overall design: Nucleosome profiling using MNAse-seq obtained from a wild-type and a top1 deleted strain under untreated conditions and after 2, 5 and 15 minutes of 1mM peroxide treatment