Tongue coating metagenome
This study aimed to develop a non-invasive diagnostic model for chronic atrophic gastritis with yellow and greasy tongue coating by integrating tongue-coating microbiota and metabolite profiles. It also identified key biomarker combinations that shed light on their potential mechanistic links with traditional Chinese medicine concepts.These samples were reviewed and approved by the Institutional Review Board of Shuguang Hospital Affiliated with Shanghai University of Traditional Chinese Medicine (approval No. 2020-834-41-01), the Ethics Committee of Shanghai Municipal Hospital of Traditional Chinese Medicine (approval No. 2022SHL-KY-14), and the Institutional Review Board of Shanghai University of Traditional Chinese Medicine (approval No. 2023-3-10-08-04). All participants provided written informed consent.