Modelling Cardiac Atrophy Utilizing Engineered Tissue Platforms by Subjecting them to Microgravity
Cardiac atrophy is the reduction in heart muscle size and function. Microgravity during spaceflight induces atrophy, providing a unique research opportunity. This study utilized engineered cardiac organoids to investigate how microgravity affects cardiac physiology, revealing insights into gene expression alteration and proteomics to yield mechanistic insights.