Suppression of inflammaging prolongs hematopoietic healthspan [dataset 4]
The impact of Thbs1 gene deletion on BM MSC activity during physiological aging is unknown. In this experiment, RNA Seq analysis was performed on BM MSCs derived from aged (18 month-old) Thbs1 knockout mice. MSCs derived from young (3 month-old) and aged (18 month-old) control mice were used as controls for comparison. Overall design: Comparative gene expression profiling analysis of BM MSCs derived from aged Thbs1 knockout mice.