Gut microbiota intervention with dietary fiber
The gut microbiota is a core regulator of immune metabolic homeostasis. Microbial metabolites (such as short-chain fatty acids and secondary bile acids) remodel the immune metabolic network through metabolic sensing pathways (such as AMPK, FXR, and TGR5). Therefore, promoting the production of these metabolites through dietary fiber is an important strategy for restoring immune metabolic homeostasis.