single-cell RNA-seq analysis for high-dose testosterone treated LuCaP 96CR PDX tumors
Our single cell RNA sequencng (scRNA-seq) analysis of high-dose testosterone (Hi-T) treated patient derived xenograft model 96CR shows RB1 positive cells displayed a robust response to Hi-T while RB1 negative cells are partiallly resistant to Hi-T. Overall design: Cells were treated with 40mg/kg testosterone ip everyday for 7 days