Multiome single-cell RNA and ATAC sequencing from Young and Old Hematopoietic Stem Cells (HSCs)
We used multiome single cell  RNA and ATAC (scRNA+scATAC) sequencing to analyze the heterogeneity in young and old HSCs Overall design: HSCs  from from Young (8-10 week-old ) and Old (22-23-month-old) C57BL/6 mice were Fluoroscent-Activated Sorted based on immunophenotypic definition (Lineage-CD34-CD48-CD150+LSK)