Delineating the evolutionary pathway to multidrug-resistant outbreaks of a Mycobacterium tuberculosis L4.1.2/Haarlem sublineage
We sought to capture the evolutionary itinerary of the Mycobacterium tuberculosis L4.1.2/Haarlem sublineage, northern Tunisia, where it caused a major multidrug-resistant (MDR-TB) outbreak, in a context strictly negative for HIV infection.