Crosstalk of gut microbiome and lung metabolites in acute lung injury induced by SARS-CoV-2 spike RBD protein.
We performed 16S rRNA diversity sequencing on the feces of COVID-19 mice model treated with SARS-CoV-2 spike RBD protein and LPS, and performed untargeted metabolomics test on the lung tissue to explore the relationship between the gut microbiome and lung metabolites in COVID-19.