TCR Beta CDR3 Repertoire in Pediatric Mycoplasma pneumoniae Pneumonia
This dataset profiles the T cell receptor beta CDR3 repertoire in peripheral blood from 206 pediatric patients with Mycoplasma pneumoniae pneumonia (MP). It reveals a restructured T-cell immune landscape characterized by reduced diversity, expanded T-cell clones, and altered V(D)J recombination features. The data further identifies M. pneumoniae-associated clonotypes, including candidates with potential cross-reactivity to common respiratory viruses, providing a resource for investigating infection-specific T-cell responses and candidate immunological biomarkers in pediatric MP.