Modeling pre-implantation development using totipotent blastomere-like stem cells [Cut&tag]
we have established TBLC-based differentiation systems to recapitulate the entire pre-implantation development Cleavage under target & tagmentation (CUT&Tag)-sequencing (CUT&Tag) for H3K4me3,H3K27ac,H3K9me3,RNA polymerase II(Pol2) and h3k27me3 in mPSC sand mTBLCs Overall design: Comparative epigenetic profiling analysis of H3K4me3,H3K27ac,H3K9me3,RNA polymerase II(Pol2) and h3k27me3 data for mPSCs and mTBLCs