Genome-wide Binding sites of TFEB during in vitro RGC to EPC differentiation (ChIP-seq)
The largest germinal niche of the adult mammal brain locates at the ventricular zone (VZ), which is made up of adult neural stem cells (NSCs) and multiciliated ependymal cells (EPCs). Both NSCs and EPCs derive from radial glia (RG), whereas the transcriptomic dynamic changes of the cell fate continuum remain elusive. Here, we used TFEB ChIP-seq to investigate its role in during EPC differentiation.