IL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [I]
To further understand the downstream mechanism of IL17/IL17R signaling in tumor cells, we performed transcriptome sequencing analysis of 4T1 cells treated with rIL17A Overall design: 4T1 tumor cells treated with or without recombinant IL-17A cytokines.