Effects of the onecut family on herpes simplex virus 1 and host chromatin accessibility in Neuro-2a cells
This is a part of the study that shows that a host gene,ONECUT2( OC2), promotes herpes simplex virus 1 (HSV-1) genome accessibility. These ATAC analyses are for viral and host genome accessibility in Neuro-2a cells. Neuro-2a cells were transfected with pOC2?HOX2 and pcDNA plasmids for 42 hours then infected with herpes simple virus1 for 2 hours. Overall design: Comparison of cells overexpressing OC2?HOX2 with control cells. Infect the cells for viral and host genome accessibility identification