Transcriptome profiling of Trichosporon asahii in response to ferrous sulfate treatment
Trichosporon asahii is an opportunistic fungal pathogen commonly associated with invasive infections, particularly in immunocompromised patients. Iron availability plays a critical role in microbial pathogenesis and metabolic regulation. In this study, we investigated the transcriptomic response of T. asahii to ferrous sulfate treatment. RNA sequencing was performed on T. asahii cultures exposed to ferrous sulfate under controlled conditions, with untreated cultures serving as controls. This dataset provides insights into iron-responsive gene expression patterns, including potential virulence factors, metabolic pathways, and stress adaptation mechanisms in T. asahii. The findings may contribute to understanding how iron availability influences the pathophysiology of this emerging pathogen.