RNA profiling to elucidate the anti-tumor mechanism of anti-CFH antibody, GT103 in mouse model of lung cancer
Complement factor H (CFH) regulates complement activation and protect host cells, including tumor cells, from attack by the alternative pathway of complement mediated cytotoxicity. In this study, we aim to explore the anti-tumor and immune stimulatory activity of an anti-CFH antibody, mGT103 in mouse model of lung cancer using bulk and single cell RNA seq