RNA-seq of the adipocytes and the stromal vasculaf fraction isolated from mice gonadal white adipose tissue
Our previous data demonstrated that treatments of young platelets(Y-Plt) mitigates the adipose tissue senescence in aged mice. Given that adipose tissue comprises various cell types, we sought to identify the primary cell population influenced by Y-Plt. Based on preliminary results indicating a more pronounced effect of Y-Plt on improving gWAT, and the abundance of aging biomarkers is relatively highest in BAT, we conducted RNA-sequencing on adipocytes and stromal vascular fraction (SVF) in both gWAT and BAT following Y-Plt treatment in aged mice.