Fecal microbiota transplantation from postmenopausal osteoporosis human donors accelerated bone mass loss in mice
The gut microbiota of 5 postmenopausal osteoporosis patients and 5 postmenopausal women with normal bone mass were collected and analyzed. Fecal microbiota transplantation was performed to determine the changes in bone mass in recipient mice. The characteristics of gut microbiota of donor subjects and recipient mice were analyzed by microbiota sequencing to clarify the changes of gut microbiota during transplantation and their relationship with bone mass