Evaluation of the effect of maternal immune activation and juvenile distress on hypothalamus of 60 day old pigs
Female and male pigs were studied. Half of the pigs were exposed to immune activation from virally-infected mothers, and half were not exposed. At 60 days of age about one third of the pigs were given metabolic distress (fasting), one third of the pigs were given immune distress (poly(I:C)), and one third of the pigs were given Saline (control). Overall design: RNA samples were obtained at 60 days of age. Hypothalamus RNA samples were subjected to paired-end RNA sequencing