NOX2 Deficiency and Microbiota in SPF Mice
This study investigates the influence of NOX2 deficiency, specifically in the p47phox and gp91phox knockout mice, on the composition of gut microbiota. The experiment included wild-type (WT) mice as a control group, and fecal samples were collected from live mice aged 7-8 weeks in a specific pathogen-free (SPF) environment. Through comprehensive analysis, we aim to elucidate the alterations in microbiota composition associated with NOX2 deficiency, shedding light on its impact in a controlled environment.