RARg bookmarking functions in prostate cancer (m6A-Seq)
To define the RARg complex in PCa cell models, including isogenic variants of 22Rv1, how this is targeted by miR-96, and regulates the AR cistrome, and how this is specifically enriched in G2/M cells and how these actions collectively shape the transcriptional programs associated with PCa outcomes. Overall design: m6A-Seq was undertaken on HPr1AR, LNCaP and 22Rv1 cells