M2 macrophages, but not M1 macrophages, support megakaryopoiesis by upregulating PI3K-AKT pathway activity
the study design on RNA-seq of the cultivated BM Macrophages from PT and GGF patients.Downregulation of the PI3K-AKT pathway is involved in the aberrant BM-M1/M2 Macrophages polarization of PT patients.