Transcriptional responses of the fetal lung after intra-amniotic LPS injection in rats [placenta]
We evaluated the transcriptional responses of the placenta to intra-amniotic inflammation induced by intra-amniotic LPS injections. Overall design: Pregnant rats were randomized to receive ultrasound-guided intra-amniotic injections of placebo (PBS) or LPS (E. coli O55:B5, 10 micrograms) on gestational day 18. Tissue samples were collected 24 hours after injection.