Gene expression profile at single cell level of LMPP (lymphoid-primed multipotent progenitor) cells from CP-CML and BC-CML patients.
LMPPs comprise of heterogeneous populations which are progenitors of lymphocytes and myeloid cells. We aim to identify the difference of distribution of the diverse populations from CP-CML versus BC-CML patients. Overall design: LMPPs from CP-CML and BC-CML were isolatd by Fluorescence-activated cell sorting (FACS) of CD34+CD38-CD45RA+CD90- cells.