A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs [RNA-seq]
We use bulk-RNA sequencing to gain deeper insights into the impact of genetic modifications on phenotypic changes in two-month-old organoids derived from two iPSC lines Overall design: Bulk-RNA sequencing data for 2-month-old WT (wildtype), PT (PTEN-/-; TP53-/-), PTCC (PTEN-/-; TP53-/-; CDKN2A-/-; CDKN2B-/-), and PTN (PTEN-/-; TP53-/-; NF1-/-) organoids samples