Genomic characterization of five commonly used endometrial cancer cell lines
An in-depth examination of five endometrial cancer cell lines in which mutation profiles, copy number variation, micro-satellite instability and homolgous recombination repair ability were determined and assessed in the context of TCGA endometrial cancer groups. Overall design: Five endometrial cancer cell lines; Ishikawa, ECC-1 Hec50co, KLE and RL95-2, were grown under optimized conditions, whole cell RNA was purified from each cell line and used for CODIS validation, RNA sequencing and MSI testing.