The_stage_and_sex_specific_transcriptome_of_the_human_parasite_Schistosoma_mansoni
I aim to characterize female- and male-specific sex-linked genes and regulatory ncRNAs that are involved in sex determination in Schistosoma mansoni. Current data sets are of pooled samples and I am unable to determine female- or male-specific transcriptional changes because the samples are combined. It is essential to have males and females separately sequenced to look at transcriptional changes that are responsible for sex determination in larval stages of S. mansoni. I have two aims for the this study: 1. Expression levels of sex chromosome gametologues across the life cycle stages to determine involvement of gametologues in sex determination during larval stages 2. Measuring and detecting sex-specific ncRNAs involved in sex determination and their association with gametologue expression