Homo sapiens Transcriptome or Gene expression
The condensin complex is required for chromosome condensation during mitosis. However its role in interphase is not clear. Neuroblastoma is the most common extracranial childhood tumor of sympathetic neuron. In human neuroblastoma, MYCN amplification correlates with poor prognosis. Results identify the genes that increased/decreased when Smc2 knockdowned in MYCN-overexperssing or control SH-EP neuroblastoma cell line.