RNA-Seq data for fallopian tube stromal cells in mice with Pdgfra-Cre mediated conditional knockout of Esr1
This is a loss of function study to investigate how conditional knockout of Esr1 in Pdgfra+ fallopian tube (oviductal) stromal cells in mice affects stromal cells directly and epithelial cells indirectly. Overall design: The conditional knockout cells are genetically marked by a Rosa26-YFP (R26Y) reporter. FACS-sorted YFP+ stromal cells from fallopian tubes (oviducts) of young adult Pdgfra-Cre;Esr1(fl/fl);R26Y experimental mice and Pdgfra-Cre;R26Y control mice were proceeded to total RNA preparation, followed by bulk RNA sequencing.