G-quadruplex-binding molecule based on napththalene diimides showing potent activity on pancreatic cancer cells
Targeting quadruplexes in cancer genes and pathways by a set of napththalene diimides-based compounds in models for pancreatic cancer. Overall design: Differential gene expression between treated and untreated MIA PaCa-2 cells after 6 h and 24 h treatment with a novel class of napththalene diimides (SOP1247), which were evaluated with RNA-seq.