Effects of taurine on skeletal muscle in senescence accelerated mice
This study investigates the molecular mechanisms of taurine in mitigating muscle aging using senescence accelerated mouse models. SAMP8 and SAMR1 mice were administered 1% taurine in drinking water from 5 to 10 months of age, with distilled water serving as the control. At 10 months, RNA sequencing was performed on the gastrocnemius muscle to identify differentially expressed genes associated with taurine is protective effects against muscle senescence and to elucidate its potential role in enhancing muscle endurance