RNA-Seq analysis of mouse neural stem cells with or wihtout Rad21 knockdown.
The precise regulation of neural stem cell quiescence and activation is crucial for normal brain development and lifelong neurogenesis. However, the mechanisms that control neural stem cell activation remains poorly understood. In this study, we investigate the role of Rad21 in this process. Overall design: RNA-seq analysis of neural stem cells that are derived from E13.5 wild type (Phf2f/f) control mice without and with treatment  shRNAs against mouse Rad21