Faecalibacterium prausnitzii promotes intestinal epithelial IL-18 production through activation of the HIF1A pathway
Wild-type Caco-2 and CRISPR/Cas9-engineered Caco-2-HIF1A-null cells were cocultured with Faecalibacterium prausnitzii in a 'Human oxygen-Bacteria anaerobic' in vitro system and analyzed by RNA sequencing.