Transcriptomic profiling of human trophoblast stem cells (hTSCs) and HTR-8/SVneo cells under  normal and MYBL2 knockdown conditions
This dataset comprises  the gene expression profiles of human trophoblast stem cells (hTSCs) and HTR-8/SVneo cells under WT and  MYBL2 knockdown conditions. RNA sequencing (RNA-seq) was conducted to examine the effects of MYBL2 depletion on gene expression, with the goal of elucidating its role in trophoblast function, including stemness maintenance, differentiation, and invasion. This dataset offers valuable insights into the molecular mechanisms governed by MYBL2 in trophoblast biology and its potential relevance to pregnancy-related disorders. Overall design: RNA-seq profiling of MYBL2 knockdown (shMYBL2) and their corresponding control (shNC) in HTR-8/SVneo cells (HTR8) and human trophoblast stem cells (hTSCs).