Single-Cell Transcriptomic Analysis of Orbital Fat in Thyroid-Associated Ophthalmopathy (TAO) Patients Group
This study focuses on the single-cell transcriptomic profiling of orbital adipose tissue (OAT) in patients with thyroid-associated ophthalmopathy (TAO). By applying single-cell RNA sequencing (scRNA-seq), we aim to characterize the cellular diversity and identify distinct cell populations in OAT, shedding light on the molecular mechanisms driving inflammation and adipose tissue expansion in TAO. The findings from this study contribute to a deeper understanding of the pathogenesis of TAO and provide a valuable resource for future therapeutic developments targeting the cellular microenvironment of orbital fat.