PD-L1 is an IFN?-independent maturation marker on tumor-associated macrophages and associates with good clinical outcome in human breast cancer
ER+ breast cancer is an immune cold cancer. We utilized single-cell RNA-sequencing to learn the cell heterogeneity in ER+ breast tumor microenvironment. Overall design: 4 primary ER+ breast tumors were collected and analyzed by single-cell RNA sequencing.