Small extracellular vesicles are mediators of embryo-endometrium-corpus luteum crosstalk
A single Day-7 in vivo or in vitro-produced bovine embryo differentially modifies the endometrial transcriptome and the miRNA content in the released sEVs, which can also lead to modifications in the miRNA profile of luteal cells. Overall design: To elucidate the embryo-endometrium-corpus luteum crosstalk, the Endometrium Explants (Ees) were cultured in the presence or absence of a single day-7in vivo(EE-AI) orin vitro(EE-IVF) embryo.