H3K27ac CUT&Tag of regenerating liver after 70% partial hepatectomy
To investigate the chromatin profiling and  transcriptional regulatory mechanism in the preparatory stage of liver regeneration, we here analyzed the genome-wide profiles of H3K27ac by CUT&Tag using control and renewal liver samples at 12 hours after surgery section. Overall design: Wild-type C57/BL6J mice were performed sham operation or 70% hepatectomy. Liver tissue was analyzed at 0 and 12 hours post resection by CUT&Tag, respectively.