UHRF1P retrogene inhibits parental UHRF1 E3 ubiquitin ligase and regulates T-cell-mediated autoimmune disease and aging
To identify T-cell biomarker or potential therapeutic target for human SLE, peripheral blood T cells were freshly isolated from 12 SLE patients and 19 healthy controls (HC) of Cohort #1 and subjected to transcriptomics analysis.