Bulk RNA-Sequencing of Jamaican Fruit Bat Placental Organoids and Fibroblasts
The Jamaican fruit bat (Artibeus jamaicensis) possesses a hemochorial placenta, the cellular composition and gene expression of which remains poorly understood. To establish a model of the Jamaican fruit bat placenta we derived trophoblast and decidua organoids and isolated primary fibroblasts. We performed bulk RNA sequencing to investigate the transcriptional profile of these placental cell types. Additionally, we examined antiviral responses using in Jamaican fruit bat trophoblast organoids using Poly I:C.