Effect of depletion of pre-existing senescent cells in aged hamstrers  on gene expression in lungs
To investigate the potential role of senescent cells in COVID19-like pathology, aged hamsters were treated with the senolytics ABT-263 one day prior to a SARS-CoV-2 infection Overall design: We performed gene expression profiling analysis using data obtained from RNA-seq of vehicle-treated aged hamsters and ABT-263-treated aged hamsters at day 7 post-infection Comparative gene expression profiling analysis of RNA-seq data