Effect of Escherichia coli O157: H7 on gene expression before and after citric acid-induced antibiotic tolerance
In order to explore the differentially expressed genes of E. coli O157: H7 after citric acid induced antibiotic tolerance, we artificially induced the antibiotic tolerance of E. coli O157: H7 and verified its phenotype. Overall design: In vitro, citric acid was added during bacterial culture to artificially induce antibiotic tolerance of E.coli O157: H7 bacteria.