H3.3B controls aortic dissection progression by regulating vascular smooth muscle cells phenotypic transition and vascular inflammation.
To investigate the function H3f3b in the regulation of VSMC phenotypic transition, we infect VSMCs with shNT or shH3f3b virus. Overall design: Comparative gene expression profiling analysis of RNA-seq data for VSMCs and its KD derivatives (shH3f3b).