Th17 cells/IL-17A shape Serotype A Pasteurella multocida infection in murine and rabbit models
The entire project revealed that PmA induced T-cell immunodeficiency and that the activation of Th17 cells/IL-17A via the IL-6-JAK2-STAT3 axis was a key mechanism against PmA. Furthermore, based on this, the application prospects of this research are proposed: targeting Th17 cells/IL-17A could be a potential strategy for the treatment of pasteurellosis and other respiratory bacterial diseases.