The impact of antibiotic on early life upper airway microbiome development and future recurrent wheezing
Upper airway microbiome plays an important role in childhood asthma development. Antibiotic use on early life of children is acknowledged for its influence on microbial compositions, the specific effects on upper airway microbiome remain poorly understood. Furthermore, there is a knowledge gap between altered upper-airway microbiome relationship and asthma inception. Here, we collected 499 nasal wash samples from 200 participants