Genomics analysis of Bap1 cerebellar nuclei
To probe the neuronal function of H2AK119ub in relation to active enhancers and promoters (H3K27ac and H3K4me3) as well as heterochromatin (H3K27me3), we generated cerebellar mutants in Bap1 (BRCA1-associated protein). We performed chromatin mapping using CUT&amp;RUN and ATACseq in addition to RNAseq.