Chromatin-enriched RNAs expression profiling by high-throughput sequencing of T47D-MTVL human breast cancer cells
Chromatin-enriched RNAs expression of T47D-MTVL human breast cancer cells expressing Dox-inducible shRNAs against multiple histone H1 variants (multiH1sh). Overall design: Stable breast cancer-derived cell lines expressing an shRNA against multiple H1 variants in response to doxycycline (Dox) were grown for six days in the absence of Dox, RNA extracted, and high-throughput sequenced. Cell lines used: inducible shRNA against multiple H1 variants under Untreated conditions (i.e. no Dox-induced depletion of any H1).