Antiparasitic effects on the gut microbiome
We tested the effects of two common antiparasitics on the gut microbiome of healthy mice to understand whether there were off-target effects on the microbiome. Mice were treated with either albendazole or metronidazole, which are a broad-spectrum anthelmintic and antiprotozoal/antimicrobial. As has been found with antibiotics, drug treatment could be having off-target effects on the gastrointestinal tract that may exacerbate symptoms of disease.