Chromatin conformation dynamics during CD4+ Tcell activation implicates autoimmune disease associated genes and regulatory elements (ATAC-Seq)
We used ATAC-seq, RNA-seq, and HiC to create atlases of the regulatory elements to provide context to autoimmune disease associated variants from publically available Genome-wide association studies Overall design: We performed ATAC-seq, RNA on 3 donors, and HiC on data from 2 donors