Mouse Liver RNA-Seq: Control vs. High-Fat Diet, Wild Type vs. PXR Knockout
Here we explore liver gene expression changes in response to PXR (pregnane X receptor) knockout under distinct dietary conditions. Wild-type and PXR-KO female mice were fed control diet (12%) or high-fat diet (45%) for 52 weeks to explore the role of PXR in obesity development during high-fat diet.