Evolutionary Patterns and Biosafety Assessment of the Resistome and Virulome in Insect-Mediated Organic Waste Management
This project aims to evaluate the ecological dynamics and biosafety of antibiotic resistance genes (ARGs) and virulence factor genes (VFGs) during the bioconversion of organic waste mediated by Hermetia illucens (Black Soldier Fly) and Musca domestica (Housefly). By utilizing integrated metagenomic and metatranscriptomic approaches, the study investigates the successional patterns of microbial communities and their associated bio-risks in full-scale industrial systems. Furthermore, the project assesses the biological safety of end-products and occupational environmental health (microbial aerosols) to provide a comprehensive framework for risk mitigation in the sustainable industrialization of insect-based waste management.