Lactiplantibacillus plantarum P10 Attenuates Renal Inflammation via Gut Microbiota Modulation
The present manuscript describes an animal experiment investigating the effects of L. plantarum P10 on uric acid reduction and hepatic XOD activity in HUA mice, involving measurements of serum biochemical and inflammatory indicators, preparation of liver and kidney pathological sections, qPCR and WB detection of uric acid transporter expression, as well as combined gut microbiota and non-targeted metabolomics analysis to explore the correlations between L. plantarum P10 intervention, gut microbiota changes, and inflammatory improvement.