Ribo-seq profiling of BMSCs with Nsun2 knockdown
This study employs Ribo-seq (Ribosome Profiling) to investigate the alterations in translational efficiency and the repertoire of translated mRNAs in Bone Marrow Mesenchymal Stem Cells (BMSCs) following knockdown of the Nsun2 gene. By comparing the translatome of control and Nsun2-deficient BMSCs, this dataset aims to uncover the role of Nsun2-mediated RNA methylation in regulating post-transcriptional gene expression and protein synthesis during BMSC differentiation, self-renewal, or other relevant cellular processes.