MCF-7 RPMI ERa and FOXA1 ChIP-seq in GDC-9545 and GNE-858
We performed ChIPseq for ER, FOXA1 and H3K27ac on MCF-7 cells treated with vehicle (DMSO), GDC-9545 or GNE-858. GNE-858 is a non-ER degrader (SERM) from the same chemical series as GDC-9545. Overall design: Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for ERa, FOXA1 or histone modification H3K27ac in MCF-7 cells.