Dissecting 16p11.2 hemi-deletion to study sex-specific striatal phenotypes of neurodevelopmental disorders
We report two bulk transcriptomic datasets of striatum from male and female mice carrying either the 16p11.2 hemideletion of 3 genes hemideletion knockout within this region. Overall design: We performed bulk RNA sequencing gene expression analysis obtained from mouse striatum for two paradigms in both males and females: the full 16p11.2 hemideletion of 27 genes (16pdelhet vs. 16pdelhetWT) and the 3 genes knockout (3geneKOMut vs 3geneKOWT).