Transcriptome of Vibrio cholerae in the intestine of adult mice
The combination of magnetic nanoparticles and gel microspheres enables the targeted recovery of Vibrio cholerae from a complex environment containing gut microbiota in the adult mouse intestine. We constructed magnetic chitin gel microspheres based on the natural aquatic host of Vibrio cholerae, to simulate Vibrio cholerae infection of mammals from natural water, and successfully obtained the full transcriptome of Vibrio cholerae in the host in situ environment.