Bulk RNA sequencing of GFER/ALR deletion in orthotopic mouse model of pancreatic cancer
This goal is to assess the transcriptional impact of GFER/ALR deficiency to pancreatic ductal adenocarcinoma in orthotopic mouse model in vivo. GFER was knockdown (KD) in KPC (KRASG12D, Trp53R172H, p48-Cre) mouse cells from an immunocompetent C57BL/6 background.