Targeting Vdac2 overcomes immunotherapy resistance by inducing tumor cell death and inflammation [scRNA-seq]
Uncovered IFNg signal and mitochondrial stress shaping tumor immune evasion Overall design: We used scRNAseq to compare gene transcriptome profiles of CD45+ immune cells and tumor cells from B16-OVA-Cas9-sgNTC/sgVdac2 tumors at day 14 after tumor inoculation in C57BL/6 mice