Capturing totipotency in human cells through spliceosomal repression [ATAC-seq]
Supplemented with splicing inhibitor PlaB, we realize in vitro culturing of human totipotent stem cells comparable to 2-4-cell blastomeres Assay for transposase accessible chromatin with high-throughput sequencing in hESC sand hTBLCs Overall design: Comparative chromatin accessibility analysis of more open and closed signals in ATAC-seq for hESCs and hTBLCs