Comparative genomic analysis of Trypanosoma rangeli
Trypanosoma rangeli is a non-pathogenic protozoan parasite that infects various mammalian species, including humans, throughout Latin America. It coexists with Trypanosoma cruzi, the etiological agent of Chagas disease, but has distinct biology in its hosts and vectors. This BioProject presents a nearly complete, high-quality genome sequence of T. rangeli (SC58 strain) and a comparative genomic analysis with different T. rangeli strains from diverse geographical regions (Choachi, C23, PIT10, and R1625). The findings reveal notable biological differences between virulent and non-virulent trypanosomatids, emphasising the genome structure, intraspecific diversity, and surface protein composition of T. rangeli, and offering new insights into the parasites biology and life cycle.