Gene expression profile of modified gapmer antisense oligonucleotides treated mouse liver
To investigate gene expression change induced by modified gapmer antisense oligonucleotides, we performed transcriptome analysis of Scarb1 ASO or PBS treated mouse livers. Overall design: Gene expression profiling of mouse liver treated 3 modified gapmer antisense oligonucleotides targeting Scarb1 or PBS at day 1, 3, and 7 after first administration.