Transcriptome profiling of kidney medulla of Actr3 KO mice
Renal tubule-specific Actr3 knockout mice (Actr3-fl/fl*Cdh16-Cre) were generated. Transcriptome profiling (RNA-Seq) and differential gene expression analysis of isolated renal medulla from KO and WT mice at p14 was performed. Actr3 KO mice showed transcriptional changes associated with Actr3 loss and kidney disease. Overall design: mRNA sequencing analysis of  kidney medulla of WT control and Actr3-fl/fl*Cdh16-Cre mice