Deficiency or targeting inhibition of histone lysine demethylase KDM5B in vivo for potential therapeutic effects on both HFrEF and HFpEF
Transcriptome sequencing of primary rat cardiomyocytes. Primary rat cardiomyocytes NRCMs infected with si-NC or si-KDM5B were treated with Ang 2. Total RNA was extracted from NRCMs using Ultrapure RNA Kit (CWBIO, CW0581). The subsequent RNA-seq assay was carried out by SEQHEALTH Technology Co., LTD.