Fustin alleviates psoriasis inflammation and keratinocyte hyperproliferation via regulating JAK-STAT3 signaling pathway (PRJCA042473)
We established FUSas a multifunctional anti-psoriatic agent that simultaneously reducing keratinocyte hyperproliferation and normalizing Th1/Th17 balance through precise modulation of the JAK/STAT3 signaling pathway. This mechanism indicated that CHR acted as a promising therapeutic candidate for psoriasis management.