Bulk and single-nucleus RNA sequencing highlight immune pathways induced in individuals during an Ixodes scapularis tick bite [RNA-Seq]
We performed RNA sequencing of skin and blood of persons presenting with naturally acquired, attached Ixodes scapularis ticks. Overall design: We leveraged RNA sequencing to define the global immune events from skin biopsies and peripheral blood in individuals with actively attached naturally acquired I. scapularis.