Antibiotics disrupt the gut microbiota, and FMT can restore it.
1.This study elucidates that antibiotic alters the gut microbiota, metabolite, and intestinal function in healthy mice.2.We demonstrated that disruption of the gut microbiota enhances susceptibility to sepsis and aggravates its pathogenesis.3.FMT restored the gut microbiota and ameliorated intestinal injury in sepsis.