Whole Exome Sequencing of Ewing sarcoma C-ES series cell lines
Patient-derived cancer cell lines are useful tools to investigate the clinically heterogeneous group of Ewing sarcoma, as they reflect patient characteristics like disease state and progression, translocation subtypes, treatment response and mutational burden. We characterized the C-ES series of the four newly established Ewing sarcoma cell lines C-ES-I, C-ES-M, C-ES-P and C-ES-Y. Here, we performed whole exome sequencing to identify the mutational backgrounds of the cell lines.