Decoding pancreatic endocrine cell differentiation and beta-cell regeneration in zebrafish
The aim of the study is to investigate the endocrinogenesis process in zebrafish pancreas during normal development and regenerative condition. Overall design: Using lineage tracing methodology (TgKI(krt4-p2a-mNeonGreen-t2a-iCre); ubb:loxp-CFP-stop-loxp-H2BmCherry), we used FACS to sort out mCherry positive cells in adult zebrafish pancreas, indicating cells in the krt4+ cell lineage