The effect of extracellular microenvironment stiffness on the differentiation of dental pulp stem cells into glial cells and its impact on osteogenesis
Inoculating human dental pulp stem cells on soft and sitff substrates to investigate the effect of substrate hardness on gene expression of dental pulp stem cells Overall design: To investigate the protective effect of substrate hardness on dental pulp stem cells, we cultured cells using two different hardness substrates (stiff and soft) and analyzed gene expression profiles based on RNA seq data obtained from dental pulp stem cells.