A novel strategy of macrophage mitophagy based on nanoantibody engineered bacterial outer membrane vesicles activating CGAs sting axis for alleviating cerebral ischemia-reperfusion injury
Nanoantibody engineered bacterial outer membrane vesicles induce macrophage mitophagy by activating CGAs sting axis, which can alleviate cerebral ischemia-reperfusion injury by reducing inflammatory response, alleviating oxidative stress, enhancing mitochondrial function, reducing apoptosis and promoting neuroprotection