Effect of  CLK2 overexpression on alternative splicing
To investigate the function CLK2 in the regulation of  alternative splicing, we established HeLa cells overexpressing GFP, CLK2 (WT), or (T343A). We then performed alternative splicing analysis using data obtained from RNA-seq of the three cell lines. Overall design: HeLa cells expressing GFP, CLK2 (WT) or (T343A) were subjected to RNA-seq