CAMKV inhibitor, OTSSP167 induces transcriptomic changes in NGP cells
To investigate the effect of CAMKV inhibitor, OTSSP167, on NB cell proliferation and delineate the mechanisms of CAMKV-mediated  pathway inhibition in NB. We treated human neuroblastoma cell line, NGP with OTSSP167 and performed gene expression profiling analysis using data obtained from RNA-seq. Overall design: We compared the transcriptomic change between OTSSP167-treated groups and the control groups.  Differential gene expression (DGE) analysis of RNA-Seq was conducted with the R statistical package DESeq2 (v1.28.1). We performed gene set analysis on DGEs by over-representation test on the ConsensusPathDB  web-portal. Genes detected in our experiments are selected on the background list.