Effect of Terpenes from Poria Cocos: Verification of Therapeutic Modes of Action for Alzheimer's Disease using Molecular Docking, Drug-induced Transcriptomes and Diffusion Network [SW1783]
This study aimed to identify the modes of action (MOA) of Poria Cocos water extract (PCW) in SW1783 cell line. Overall design: Comparative gene expression profiling analysis of RNA-seq data for PCW (500 ug/mL, 100 ug/mL, and 20 ug/mL, respectively), positive control (wortmannin 10uM and LY294002 10uM, respectively), and vehicle control (2% DMSO).