Mus musculus strain:C57BL/6 Raw sequence reads
The central aim of this study was to examine the efficacy of CAR-M against inflammation in relevant models of kidney and liver diseases. We have demonstrated that CAR-M can dynamically switch its phenotype and function to become anti-inflammatory in response to the inflammatory molecule. Infused CAR-Ms attenuated inflammation and injury in both acute and chronic inflammatory kidney diseases, as well as inflammatory liver disease.