Oral Microbiome Signatures Associated with Glycemic Control in Pediatric Type 1 Diabetes
This study investigates the oral microbiome composition in children with Type 1 Diabetes (T1D) stratified by glycemic control status. Using 16S rRNA gene sequencing, we profile oral microbial communities in two cohorts: controlled T1D (HbA1c < 6.5%) and uncontrolled T1D (HbA1c >= 6.5%). The primary objective is to identify microbial signatures and dysbiotic patterns associated with glycemic control and T1D status. This dataset provides insights into the microbiome-immunity axis in pediatric T1D and supports the discovery of microbiota-based biomarkers for disease monitoring and therapeutic development.