Tumor-derived Small Extracellular Vesicles Inhibit CAR T Cells
To examine the effect of tumor-derived small extracellular vesicles on Meso-CAR T cells. Series of genes of CAR T cells treated with or without tumor-derived small extracellular vesicles were detected. Overall design: Meso-CAR T cells were treated with or without tumor-derived small extracellular vesicles. Those small extracellular vesicles were purified from tumor cells with or without PD-L1 KO cells