Gene expression analysis of RECQ1-regulated transcriptome in breast cancer cells.
The goal of this study was to identify the RECQ1-regulated transcriptome and comparing it to the ER alpha-regulated transcriptome using RNA-seq in breast cancer cells. Overall design: MCF7 cells were transfected with control siRNA or siRNAs (smartpool) against RECQ1 or ESR1. Total RNA was isolated and subjected to mRNA seq.