Therapeutic Mechanisms of Wudan on Chronic Atrophic Gastritis in Rats (PRJCA045797)
The primary objective of this study was to investigate the therapeutic potential and underlying molecular basis of Wudan (WD) in chronic atrophic gastritis (CAG). Using both in vivo rat models and in vitro gastric epithelial cells, we aimed to determine whether WD could ameliorate pathological changes and restore cellular homeostasis. Transcriptomic sequencing, combined with functional validation, was employed to identify key biological processes affected by WD treatment. This project provides fundamental evidence supporting the role of WD in alleviating CAG and offers publicly available omics data for further exploration of its mechanisms.