Engineered exosomes reprogram Gli1+ cells in vivo to prevent calcification of vascular grafts and autologous pathological vessels
Engineered exosomes reprogrammed Gli1+ cells to promote SMC reconstruction and inhibit calcification in TEVBs and autologous pathological vessels. Overall design: After engineered exosome therapy in rats with chronic renal disease, comparative gene expression profiling analysis of RNA-seq data for aorta and thoracic aorta