Dip2b knockout affects neural differentiation of mESCs by depressing axonogenesis and axon guidance and facilitating ECM-receptor interaction
To investigate the biological function of Dip2b during the neural differentiation process of mESCs, we established a Dip2b homozygous knockout 46C ES cell line using the CRISPR/Cas9 genome editing technology Overall design: Comparative gene expression profiling analysis of RNA-seq data for Dip2b knockout cells and WT cells during the neural differentiation at different time points