Changes in miRNA expression in offspring hypothalamus after exposure to maternal obesity
The purpose of this study was to identify miRNA that are differentially regulated in the arcuate nucleus of the hypothaamus (ARC) and paraventricular nucleus of the hypothalamus (PVH) after perinatal exposure to maternal obesity. Overall design: c57bl6J mouse model of maternal obesity. This sequencing data is from the male offpsring of lean or obese dams when offspring were 8 weeks of age. All aninals were culled in fed state. Arcuate nucleus and paraventricular nucleus was laser captured from cryostectioned brains for RNA extraction.