Single-cell RNA sequencing of the kidneys from kidney-resident macrophage deplated mice
The purpose of this study is to investigate the long-term depletion of kidney-resident macrophages (KRMs) and their role in regulating tubulointerstitial nephritis (TIN) through specialized efferocytosis and interaction with neighboring T cells. Overall design: We prepared scRNA-seq datasets from KRM-depleted mouse 6 weeks after anti-colony stimulating factor 1 receptor antibody (aCSF1R Ab) injection.