An age-specific differentiation path from hematopoietic stem cells contributes to exacerbated thrombosis
To investigate the transcriptome of age-specific MkPs compared to canonical MkPs Overall design: mRNA levels were examined in Young or Old Lin-cKit+Sca1-CD150+CD41+GFP+ or Tom+ cells, or  Old Lin-cKit+Sca+-CD150+Flk2-Tom+ cells FACS sorted from the bone marrow of Young or Old FlkSwitch mice