Activation of Notch2 signaling drives cyst growth in kidney [RNA-seq: R26NICD2 Pax-rtTA]
In order to investigate how NICD2 promotes cyst growth, we carried out bulk RNA-Seq analysis of kidneys from PKD mouse model R26NICD2/+ Pax8-rtTA mice. Overall design: mRNA profiles of 8-week old wild type and R26NICD2/+pax8cre