Analysis of senescence transcriptome upon knockdown of XPO7 [RNA-seq]
We depleted XPO7 by shRNA in IMR90 ER:RAS cells. 5 days after RAS induction by treatment with 4OHT we collected RNA. XPO7 depletion alleviates senescence induction. Overall design: 4 conditions in triplicate. IMR90 ER:RAS cells, either: non-induced control cells (non-senescent), 4OHT induced cells (Senescent, induced), IMR90 ER:RAS cells,  4OHT-induced  and  with XPO7 depletion (by expressing shXPO7_3), IMR90 ER:RAS cells,  4OHT-induced  and  with XPO7 depletion (by expressing shXPO7_5)