Effect of SMNDC1 small molecule inhibition on gene expression
To investigate the effect of treating alphaTC1 cells with a small molecule inhibitor against SMNDC1, we treated cells with DMSO (control) or compound (G786-1089) for 16h. We then performed gene expression profiling analysis and splicing analysis using data obtained from RNA-seq. Overall design: Comparative gene expression profiling analysis of RNA-seq data for alphaTC1 cells treated with SMNDC1 inhibitor or DMSO, 3 replicates for each condition.