Binding of full length p73 (TAp73alpha) and cancer-specific variant (DNp73beta) to genome of melanoma cell line SK-Mel-29
All p73 isoforms share an identical DNA-binding domain. These CUT&RUN datasets for TAp73a, DNp73ß, and a GFP control illustrate the isoform-specific differences in genomic binding. As no antibodies are currently available that selectively recognize individual p73 variants, the data were generated following overexpression of the individual variant.