RNA-seq profiles of HepG2 control cells and HepG2-HBx cells
Hepatocellular carcinoma (HCC) is mainly associated with chronic hepatitis B virus infection. Hepatitis B virus X protein (HBx) is closely related to the occurrence of liver cancer. To explore the molecular mechanism by which HBx affects the occurrence of hepatocellular carcinoma, we established a stable HCC cell line HepG2-HBx expressing HBx and analyzed the transcriptome profile by RNA-seq. Overall design: Six samples of HepG2 cells were analyzed. Three replicate samples of HepG2 cells transfected with HBx plasmid and three replicate samples of HepG2 cells transfected with pmCherry-N1 (control) plasmid.