Metabolic and transcriptomic reprogramming in the transition from a proliferative to a quiescent state is mediated by YAP-dependent and YAP-independent mechanisms.
To investigate the proliferation-to-quiescence transition we looked at metabolic flux and gene expression in proliferating (P) and quiescent (Q) mouse embryonic fibroblasts. Overall design: Comparative gene expression profiling analysis of RNA-seq data for Proliferating (P) and Quiescent (Q) cells.