Plasmodium falciparum sporozoite transcriptional response to CD36
The experiment was designed to assess whether the endothelial receptor CD36, which we identified as a new host receptor for P. falciparum sporozoites, triggers a transcriptional response in sporozoites. We compared  global gene expression patterns in sporozoites subjected to host-like temperature and serum activating conditions, with or without CD36 exposure. Sporozoites were subjected to these host-like conditions separately or combined, to pinpoint the response to CD36 alone.