Recombinant walnut-derived peptides against D-gal-induced cognitive deficits
This study aims to investigate the effects of recombinant walnut-derived peptides (rWDP) on gut microbiota composition and senescence-related changes in a D-galactose (D-gal)-induced aging mouse model. The research is highly relevant as it explores how dietary interventions, such as rWDP supplementation, can modulate gut microbiota and potentially counteract aging-associated physiological decline. Mice were divided into three groups: a control group receiving sterile saline, a model group treated with D-gal to induce senescence, and an rWDP group administered both D-gal and rWDP. After 60 days of treatment, cecal feces were collected for 16S rRNA sequencing to analyze changes in gut microbiota. The findings may provide valuable insights into the role of gut microbiota in aging and highlight the potential of rWDP as a therapeutic agent to promote healthy aging.