Functional genomic analyses of iPSC-derived pancreatic progenitor cells
The goal of this study is to molecularly characterize regulatory variation in pancreatic progenitor cells (PPC). Here, we derived PPC from iPSCs of nine iPSCORE individuals (DeBoever et al., 2017; Panopoulos et al., 2017), and generated RNA-seq, ATAC-seq, scRNA-seq, and snATAC-seq. We strive to understand the role of functional genetic variation during fetal pancreatic development that later give rise to adult pancreatic diseases. Overall design: Transcriptome and chromatin accessibility maps of iPSC-PPCs. **Submitter states that the raw data will be available in dbGaP (phs000924)**