Periosteum Signatures of Delayed Fracture Healing in Type 2 Diabetes at Single-Cell Resolution
Purpose: Periosteum is highly involved in bone generation. We used single cell RNA sequencing(scRNA-seq) to analyze the heterogenity of periosteum from db/+ and db/db mice, fractured or post-fractured, and the homology of periosteum from mice and human. Overall design: scRNAseq of periosteum from db/+ and db/db mice, fractured or post-fractured, and T2DM patient