Whole Genome Sequencing-Based Resistome Analysis of MDR and XDR Escherichia coli Isolated from Chronic Kidney Disease Patients
This study focuses on the use of whole genome sequencing (WGS) to analyze the resistome of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Escherichia coli isolated from patients with chronic kidney disease (CKD). It aims to identify the genetic determinants responsible for antimicrobial resistance and to understand their distribution among clinical isolates. The findings provide valuable insights into resistance mechanisms and support the development of effective treatment strategies and infection control measures.