High-Depth RNA-seq Data to Investigate Gene Regulation Mediated by Phase-Variable DNA Methyltransferases in Serogroup B Neisseria meningitidis.
Neisseria meningitidis is a leading cause of bacterial meningitis and septicemia. Here, we report high-depth RNA-sequencing for N. meningitidis serogroup B strains MC58, B6116/77, and M0579. These strains encode phase-variable DNA methyltransferases ModA11, ModA12, and ModD1, respectively, which act as global epigenetic regulators central to meningococcal pathogenicity.