Identification of the downstream target genes of TGFbeta
This study aimed to explore the downstream target genes of TGFbeta in normal gastric cell line GES-1. Overall design: The GC cell lines were treated with or without recombinant human TGF-beta protein. After effective transcrection, the genes downregulated by TGF-beta were screened by RNA sequencing. The transcriptome sequencing studies were performed by deep sequencing, using Illumina NovaSeq 6000.