Gene expression profile of ACSA-2+/O1-/CD11b-/Cd45-/Olig4- astrocytes from the brain I
We used bulk RNA sequencing to investigate the molecular signature of astrocytes affected by PU.1 inhibitor in APP/PS1:APOE4 KI mice. Overall design: ACSA-2+/O1-/CD11b-/Cd45-/Olig4- astrocytes were isolated by Fluorescence-activated cell sorting (FACS) and analyzed using Smartseq2 RNAseq.