Ex Vivo Model for Oral Bacterial Biofilms
Antibacterial screening using Ex Vivo Models. A method to allow detection of oral bacteria that are targets of antibacterials. The method uses ex vivo testing of effects of test agents on oral bacteria in aggregates as isolated from saliva in a way that produces reproducible results with tests done on different days independent of time sample acquisition. Uses 16rRNA levels as a readout of agent toxicity.