Gene regulatory consequecnes of loss of Kdm1a in the kidney [ChIP-Seq]
Histone methyltransferases and demethylases play crucial roles in gene regulation and are vital for the proper functioning of multiple tissues. In this study, we investigated the functions of Kdm1a by employing a renal progenitor-specific deletion during kidney development and evaluated global differences in H3K9 trimethylation between control and Kdm1a conditional knockout kidneys using Chromatin Immunoprecipitation DNA sequencing (ChIP-seq). Overall design: Chromatin immunoprecipitation DNA sequencing for H3K9me3 in Kdm1a control and conditional knockout kidneys.