Gut Microbiome Characteristics of Hypothyroidism in Early Pregnancy Detected by 16S rRNA Amplicon Sequencing and Shotgun Metagenomics
60 pregnant women (30 with hypothyroidism and 30 normal controls) were recruited for 16SrRNA gene sequencing, and 6 cases from each group were randomly selected for metagenomic sequencing to assess the gut microbiota profile.