RNA-Seq of primary CKD osteoblasts
Primary osteoblasts from patients with end-stage kidney disease have defective maturation and mineralization characteristics in vivo and in vitro.  This study was designed to evaluate signaling pathways associated with this abnormal maturation phenotype. Overall design: Cross-sectional RNA-Seq analysis of primary osteoblasts from 9 pediatric end-stage kidney disease patients and 3 healthy controls grown to confluence