Spatial Transcriptomics of ageing mouse liver tissues give insights into the zonation-specific lipid deposition
To gain in situ information on the transcriptional profile of the different zones upon ageing, we used the 10X Genomics Visium Platform and ran 5µm tissue cryosections from livers of 2 young and 2 old mice. We investigated the transcriptional events that differentiate lipid metabolism in ageing, across the different zones of the liver tissue.