ILC3 inhibits Osteoclastogenesis and ameliorates Inflammatory Bone Loss in Post-menopausal Osteoporosis
This study shows that a type of immune cell called ILC3 helps protect bones by preventing excessive bone breakdown. In conditions like postmenopausal osteoporosis, these protective cells become imbalanced and less effective, partly due to changes in gut bacteria. This imbalance contributes to increased bone loss. The findings suggest that targeting these immune cells could offer new ways to treat or prevent osteoporosis.