Whole genome sequencing of yeast CYClones mapping population
The CYClones (Collaborative Yeast Cross clones) mapping population was constructed using a multiparent funnel cross breeding scheme. This experimental design is analogous to the Mouse Collaborative Cross, with eight haploid “founder” strains isolated from distinct geographic and environmental sources.Construction of the CYClones library employed three rounds of crossing to produce 11,484 haploid strains that are recombinant mosaics of the eight founder haplotypes.