Gene expression analysis of double conditional knockout mice for Sbno1 and Trp53
This BioProject investigates gene expression profiles in double conditional knockout mice for Sbno1 and Trp53. To generate these knockouts in the developing forebrain, Sbno1 floxed mice, Trp53 floxed mice, and the Emx1-Cre driver line were utilized. RNA-seq was performed on the telencephalon at embryonic day 12.5 (E12.5) and the cerebral cortex at embryonic day 18.5 (E18.5) to elucidate the roles of Sbno1 and Trp53 in neural development.