Characterization of the nasal microbiome and metabolome in children with Henoch-Schonlein purpura and children with Henoch-Schonlein purpura nephritis
Three groups of eligible subjects were included, including 20 cases in the HSP group, 20 cases in the HSPN group, and 20 cases in the healthy control (HC) group. Nasal lavage samples from each group were subjected to 16SrRNA gene sequencing and metabolomic analyses to screen differential flora and differential metabolites, and Spearman correlation analysis was done.