A conserved transcriptional program for MAIT cells across mammalian evolution [Hsapiens_thymus_MAIT]
Mucosal-Associated Invariant T (MAIT) cells recognize the riboflavin pathway-derived metabolite 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil (5-OP-RU) presented by the MHC-Ib molecule MR1. Both MR1 and the T cell receptor genes used by MAIT cells are Overall design: Hsapiens_thymus_MAIT