The protection of SANQI and HuangLian on the MCAO-induced ischemia reperfusion injury at day 7
Middle cerebral artery occlusion(MCAO) model in rats was prepared by modified thread occlusion method, and were subjected to MCAO surgery for occlusion for 90 minutes and then followed by reperfusion for 7 days. And Coptis alkaloids and Total saponins of Panax notoginseng was administrated dayly by gavage. At day 7, the rats were sucrificed and the brain sections were harvested for RNA-SEQ sequencing.