Transcriptome profiling based on the presence of Amcf1 under basal and starvation conditions
This study investigates the role of AMC-F1 in transcriptional regulation using RNA sequencing (RNA-seq). Mouse embryonic fibroblasts (MEFs) derived from Amcf1 knockout (KO) mice and their wild-type (WT) littermates were analyzed under basal and starvation conditions.The objective is to identify differentially expressed genes and pathways involved in autophagy, mitochondrial dynamics, and cellular stress responses, providing insight into the role of AMC-F1 in maintaining cellular homeostasis. This dataset serves as a resource for further investigation into AMC-F1-mediated regulatory mechanisms.