Regulatory Roles of PUM1 and PUM2 during mouse ESC differentiation
This study explores the functions of PUM1 and PUM2 in mouse embryonic stem cell (ESC) differentiation by examining their regulatory roles in gene expression. We utilize RNA sequencing (RNA-seq) and RNA immunoprecipitation sequencing (RIP-seq) to analyze changes in transcriptomes and to identify the RNA targets of these proteins during ESC differentiation. The goal is to understand how PUM1 and PUM2 contribute to cell fate decisions and development processes, providing insights that could impact regenerative medicine and developmental biology. This dataset includes comprehensive profiles of gene expression and protein-RNA interactions, offering valuable resources for researchers studying developmental biology and gene regulation.