Global transcriptomic profiles of E. coli transformed with recoded mNeonGreen2
The study aimed to develop a new approach for modifying the genetic code of the mNeonGreen2 protein by systematically changing its codons to optimize the usage of adenine nucleobase across specific amino acids in vivo. We analyze the global transcriptomic profiles of E. coli transformed with the recoded mNeonGreen2 constructs to assess the effects of heterologous recoded constructs on the expression of other genes in the cell.