LncRNAs regulate FBL to facilitate rRNA processing in cancer cells
We identified lncRNA DNAJC3-AS1 can buffer the behavior of FBL condensation in cancer cell. In this study, we preformed the FBL-TurboID-RIP and Single-end Enhanced Cross-linking and Immunoprecipitation (seCLIP)  sequencing to to identify candidate RNAs that bind to FBL or its adjacent proteins. The FBL-binding regions distributed throughout the sequence of lncRNAs were also discovered. Overall design: 1.  MOLM-13 and SW480 cells used in the  FBL-TurboID-RIP-seq. 2. HEK293T cells  used in the  FBL-seCLIP.