Transcriptional Signatures of the Right Ventricle in End-Stage Heart Failure
We utilized bulk RNA-sequencing of myocardial tissue to describe transcriptional changes that occur in the RV: 1) In the context of stress from left-heart failure by comparison to controls and 2) As the RV progresses from compensation to decompensation. We further compared transcriptomic changes that occur in RV failure to the transcriptomic changes that occur in LV failure.