Low-coverage whole-genome sequencing of Diversity Outbred mice (n = 183, eQTL) (house mouse)
DNA isolated from 183 DO embryoid bodies (J:DO; RRID:IMSR_JAX:009376) were sequenced to approximately 1X coverage. Reads were then aligned and used for genotype imputation. Each genome was then reconstructed in terms of the DO founder strain haplotypes. Haplotype calls were used to identify expression quantitative trait loci (eQTL) and compare to those mapped with haplotype reconstructions from the Giga Mouse Universal Genotyping Array.