The effect of EIF4A3 knockdown on gene translation in EBV-positive cells
Eukaryotic initiation factor 4A3 (EIF4A3), a core helicase component of the exon junction complex, is essential in Epstein-Barr virus infection with unknown role . Thus RNA-seq analysis was performed to explore the effect of depletion of EIF4A3 in EBV-positive cells(C2089 cells). Results showed that the depletion of EIF4A3 could broadly regulates cellular gene translation.