Transcriptomic profiling of SK-MEL-28 melanoma cells treated with TAE684
This study investigates the transcriptomic changes in human SK-MEL-28 melanoma cells after treatment with different concentrations (0, 0.8, or 1.6 uM) of the ALK inhibitor TAE684 for 48 hours. RNA sequencing was performed to explore gene expression alterations related to drug response and resistance mechanisms.