RNA-sequencing analysis of oncospheres from control and SNORD88B-deficient HCC cells
To explore the role of small nucleolar RNA, SNORD88B on self-renewal of liver cancer stem cells (CSCs), we enriched contorl or SNORD88B-deficient HCC oncospheres. Overall design: Then RNA-sequencing analysis were performed and differentially expressed genes were identified. Total RNAs were extracted from oncospheres and subjected to RNA-sequencing analysis  through BGISEQ-500 platform