Effect of SARS-CoV-2 infection on gene expression of iPSC derived sensory neurons [scRNAseq]
To investigate the impact of SARS-CoV-2 on the peripheral nervous system, we generated human sensory neurons from induced pluripotent stem cells (iPSC) that we further infected with the SARS-CoV-2 strain WA1/2020 for 48 hours. Overall design: In this experiment, we co-cultured HEK293T cells and sensory neurons for 3 days, infected the cultures with SARS-CoV-2 for 48h, and analyzed using scRNAseq.