16S rRNA gene sequencing of ileal microbiota in Tibetan sheep following rumen fluid transplantation
This project provides 16S rRNA gene sequencing data of ileal microbiota from Tibetan sheep treated with rumen fluid transplantation (RFT). The study aimed to evaluate the effects of RFT on gut microbial composition and its association with host immune and metabolic regulation. Microbial community analysis revealed significant shifts in bacterial structure, with increased abundance of potentially beneficial genera such as Prevotella, Ruminococcus, and Lactobacillus. These microbial changes were associated with host immune markers and metabolic parameters. The data contribute to understanding how microbiota modulation influences gut function and systemic regulation through the gut liver axis, and provide a resource for studying microbiome based strategies in ruminant health.