Patient-derived colon organoids mRNA sequencing under growth and differentiation conditions
This dataset contains raw mRNA sequencing data (FASTQ) generated from patient-derived colon organoids. Organoids were established from histologically normal human colon tissue and cultured under two conditions: proliferative (growth) and differentiation-inducing medium. For each condition, duplicate cultures were generated from the same patient to assess reproducibility. The dataset includes all raw sequencing reads and associated metadata for each sample, supporting analysis of transcriptional differences between proliferative and differentiated epithelial states. All samples were de-identified prior to sequencing.