Whole transcriptome sequencing for upper tract urothelial carcinoma (UTUC) of BALB/c female mice treated with N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)
Only BALB/c female developed UTUC treated with BBN. To know the biological features of UTUC, we conducted the RNA-seq. Overall design: BALB/c female were treated with or without BBN for 18 weeks. The UTUC developed side of ureter, non-UTUC developed side of ureter and bladder from BALB/c female treated with BBN, and normal ureter and bladder from BALB/c female treated without BBN were harvested. mRNA expression of each group was evaluated by RNA-seq and functional analysis