LILRB1 and LILRB2 characterization in Old World Monkey species
In humans, the leukocyte immunoglobulin-like receptor family is extensively studied with respect to health and disease. In this study the focus is on characterization of the LILRB1 and LILRB2 polymorphism, which are inhibitory receptors that interact with MHC molecules. Multiple polymorphic sides are identified in the human LILRB1 gene. In this study, rhesus and cynomolgus macaques and hamadryas baboons were selected and characterized for LILRB1 and LILRB2 at the genome and transcriptome level.