Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [WES]
To define the cellular composition and spatial architecture of the tumor micoenvironment, we combined single-cell RNA-sequencing, spatial transcriptomics, and multiplexed ion-beam imaging from 10 patient cutaneous squamous cell carcinoma tumors and  site-matched normal skin Overall design: Genomic DNA was isolated from patient tumors and normal skin and whole-exome squencing was performed