Lats1/2 depletion in male murine steroidogenic zG adrenocortical cells
In order to understand the role of Hippo pathway in  mice adrenal glands, we inactivated lats1/2 in a transgenic mouse model using the cre recombinase system in aldosterone-producing zG cells. RNAseq analysis on whole adrenal glands were performed on male mice Overall design: RNAseq gene expression profile for  WT (Lats1flox/flox;Lats2flox/flox) and KO mice adrenal glands (Lats1flox/flox;Lats2flox/flox;AS-cre) (n=3/group)