Targeted DNA sequencing on a cohort of Poor Risk AML samples
Targeted sequencing on a cohort of 57 samples from the Barts Health NHS Trust (London) harbouring poor-risk cytogenetic aberrations including -7/del(7), -5/del(5), KMT2A rearrangements (other than t(9;11)), t(6;9), inv(3), -17/del(17) and complex karyotypes (= 3 chromosomal aberrations).  Library Preparation was carried using the TruSight Myeloid Sequencing Panel. Reads were sequenced with a NextSeq 500.