The alterations of gene expression profiling induced by EXOSC10-AS1 knockdown in HCT116 cells.
Long noncoding RNAs (lncRNAs) have been identified to play increasingly important roles in tumorigenesis, and they may serve as novel biomarkers for cancer therapy. Here we report gene expression profiles of HCT116 cells treated with EXOSC10-AS1 siRNA. This study reveals a novel role of EXOSC10-AS1 in downstream gene regulation and provides a new explanation of EXOSC10-AS1' s function in colorectal cancer. Overall design: RNA-seq after knockdown of EXOSC10-AS1 by siRNA in HCT116 cells.