CUT&Tag Profiling of PBX1 and H3K27ac Binding in Human Colorectal Cancer Cells
In this study, CUT&amp;Tag was used to profile PBX1 binding sites and H3K27ac histone modification in human colorectal cancer cells. PBX1 is a key transcription factor involved in various oncogenic pathways, while H3K27ac marks active regulatory regions such as enhancers. By generating genome-wide maps of these factors, this dataset aims to uncover how PBX1 and H3K27ac collaborate to drive gene expression in cancer. This data will be useful for investigating the regulatory networks that influence tumor progression and therapy resistance in colorectal cancer.