Adipophilin as a metabolic biomarker for Uveal Melanoma
In this study, we designed four adipophilin-based multigene signatures for uveal melanoma prognostication using a transcriptomic and secretome survival-functional network approach. To validate the adipophilin-based multigenes and adipophilin expression levels in the context of BAP1, we used next generation RNA sequencing approach. Overall design: Comparative gene expression profiling analysis of RNA-seq data for two uveal melanoma cell lines, Mel285 (BAP1 positive) and MP46 (BAP1 negative) cells lines