The effect of LIG (ligustilide) on gene expression in liver of mice undergoing BDL-induced liver fibrosis.
In order to evaluate whether LIG produces the anti-fibrotic effects in the liver,we established BDL-induced liver fibrosis mice model and administered with LIG. Then,  we collected liver tissues and employed RNA-seq analysis. Overall design: Mice were randomly divided into sham, bile duct ligation (BDL) and BDL + 10 mg/kg LIG. Liver tissues were collected at the end of different treatment. Total liver RNA was extracted and RNA-sequecing was performed.