Non-canonical AMPA receptor blockade reduces lymph node egress and neuroinflammation [scRNA-seq]
Disturbances in the glutamatergic system have been linked to neuronal pathology. Investigating therapeutic translation, we discovered immune-related effects for the selective non-competitive AMPA receptor blocker perampanel in mouse models of multiple sclerosis. Overall design: Comparative gene expression profiling analysis of RNA-seq data for EAE perampanel treated mice and controls