Single Cell RNA Sequencing of Human Intestinal Organoids from Pluripotent Stem Cells
This project aims to elucidate the molecular mechanisms regulating tuft cell differentiation in the human intestine. By performing single-cell RNA sequencing on tuft cell enriched human PSC derived intestinal organoids, we identify gene expression profiles and signaling pathways that drive tuft cell development. The dataset offers valuable insights into intestinal immunity and cell lineage regulation, providing a foundational resource for future studies and potential therapeutic innovations targeting intestinal disorders.