16S rRNA sequencing of C57 mouse fecal samples
The project was divided into four groups(n=5 per group): the low-fat diet group(LC), the low-fat diet plus periodontitis group(LP), the high-fat diet group(HC), and the high-fat diet plus periodontitis model group(HP). the low fat diet group made up 10% of their total caloric intake, while the high-fat diet group comprised 60% of their total caloric intake.Liver steatosis was observed in mice following 12 weeks of HFD feeding. Then, mice fed low-fat and high-fat diets were randomly assigned to ligated and unligated groups. The ligated groups (LP and HP) underwent periodontitis induction via ligation of the maxillary second molars using 7.0 suture. LC_J69, LC_J70, LC_J77, LC_J80, LC_J81; HC_J32, HC_J34, HC_J35, HC_J36, HC_J37; LP_B51, LP_B53, LP_B54, LP_B55, LP_B56; HP_A79, HP_J8, HP_J9, HP_J10, HP_J58.