Crnic Institute Human Trisome Project - JAK inhibition in Down syndrome: PolyA RNAseq from whole blood
Analysis of steady-state mRNA levels in whole blood of  subjects with Down syndrome (trisomy 21) and qualifying moderate-to-severe immune skin conditions. This dataset is part of the Human Trisome Project run by the Linda Crnic Institute for Down Syndrome at the University of Colorado Anschutz Medical Campus. http://www.trisome.org/ Overall design: Comparison across 10 subjects with Down syndrome at baseline and after treament with the JAK inhibitor tofacitinib for 2, 8, and 16 weeks.