Transcriptome modulation by Caspase-8 inhibition
The goal is to evaluate the transcriptomic changes in murine neutrophils and macrophages after chemical inhibition of Caspase-8. Bone marrow-derived neutrophils and macrophages were pretreated with the z-IETD-fmk Caspase-8 inhibitor or vehicle and analyzed for Differential Gene Expression by RNAseq.