RNA seq of HEK293 treated with Blebbistatin or expressing C9orf72 associated Di Peptide Repeats (DPRs)
To identify if the alteration of Myosin activity identified in DPRs expressing cells induced alterations in the transcriptome profile of cells. For that purpose, we compared the changes in HEK293 cells transcriptome induced by a known myosin activity disruptor, Blebbistatin, with DPRs expressing cells .