Dual RNA-seq analysis of gene co-expression and immune response mechanisms in chickens infected by Eimeria tenella
We have analyzed immune chickens undergoing a secondary E. tenella infection using dual RNA-seq. Samples were taken from caecal tissue where the parasites replicate at six timepoints between 0 and 10 days post infection. The results that immune chickens have a much faster response to E. tenella compared to that of naïve chickens, and that there is a clear IFN-signature Overall design: mRNA profiles of chicken caeca infected with Eimeria tenella sporozoites, taken from 6 timepoints with 6 biological replicates each.