Microbiome in Recurrent Acute Otitis Media
We conducted a cross-sectional observational prospective study involving 38 children aged 1 to 6 years. The test group comprised children with rAOM, while the control group consisted of generally healthy children. Amplicon sequencing of the V3-V4 hypervariable region of the 16s rRNA gene was used to analyze the microbiota in feces and nasopharyngeal swabs.