Knockdown of ERp19 promotes ferroptosis in colon cancer cells through glutathione depletion
To investigate the function of ERp19 in the ferroptosis, we established HT-29 cell lines in which target gene has been knocked down by shRNA. We then performed gene expression profiling analysis using data obtained from RNA-seq of HT-29 shNC and HT-29 shTXNDC12 cell lines at the same time points