Clinical Emergence of Inducible Macrolide Resistance Mediated by Acquired erm(41) C28T Mutation in Mycobacterium abscessus
Inducible macrolide resistance mediated by the erm(41) T28 allele is a well-characterized intrinsic mechanism in Mycobacterium abscessus. Here, we report a case of M. abscessus pulmonary disease in which an initial erm(41) C28 isolate acquired inducible macrolide resistance via an erm(41) C28T point mutation during prolonged therapy.