Caco2 colorectal cancer cell line with individual knockouts of CD133 and TRIM28
We systematically compared the effects of individual knockouts of CD133 and TRIM28 on a range of fundamental cellular properties in Caco2 cells. We performed RNA-seq-based transcriptomic profiling and analyzed the expression patterns of a broad panel of membrane-associated markers representing distinct functional categories in the knockout cells compared to the wild-type Caco2 cells.