Co-culture of Aspergillus nidulans and Aspergillus fumigatus
Fungal genomes contain genes for far more secondary metabolites (SMs) than have yet been identified in the laboratory. To explore silent SMs, co-culturing method has attracted much attention in this field. However, study of the molecular mechanisms underlying this effect is in its infancy. For this purpose, we used strains of Aspergillus nidlulans and Aspergillus fumigatus in co-culture to enhance SM production.