Longitudinal genotyping study of GNAO1 G203R neuron growth compared to normal neurons
Bulk RNA sequencing of patient-derived neurons generated by dual-SMADi approach. Patient has NM_020988.3(GNAO1):c.607G>A pathogenic variant. Sequencing is done on day 7, day 11, and day 60 neurons with CRISPR-corrected and mutant-allele-knockout controls.