Combining_VIDISCA_virus_discovery_with_Illumina__Deep_Sequencing
VIDISCA is a powerful method for identifying novel infectious agents in a sequence independent manner.(van der Hoek et al, 2004, Nature Medicine 10:368-73). The sensitivity of the method would be greatly enhanced by coupling VIDISCA with  the deep sequencing provided by Illumina methods. The current study is exploring the sample preparation conditions and the adapters required to merge these two methods.