L-beta-galactoglucan alleviates loperamide-induced constipation in mice and regulates gut microbiota and metabolism
In this study, we report for the first time the protective effects of L-beta-galactoglucan derived from Agrobacterium sp. FN01 against loperamide-induced constipation. Mouse models were established by oral administration of loperamide (10 mg/kg), and concurrently treated with L-beta-galactoglucan at doses of 0, 200, 400, or 800 mg/kg for two weeks.