Nuclease CAD restrains cGAS-STING signaling to inhibit radiosensitivity of colorectal cancer
Targeting CAD enhances radiosensitivity by modulating cGAS-STING pathway activation, highlighting the significance of CAD as a potential therapeutic target for CRC. Overall design: To investigate the role of CAD, we performed RNA-seq analysis on control and CAD knockout (KO) HCT116 cell lines for subsequent enrichment analysis.