Endoplasmic reticulum protein TXNDC5 interacts with PRDX6 and HSPA9 to regulate glutathione metabolism and lipid peroxidation in hepatic AML12 cell line
The goal of this study was to determine TXNDC5 hepatic transcriptome interaction by comparing high-throughput data for KO vs. WT AML12 cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for AML12 cells and its KO and KI derivatives. TXNDC5 was overexpress using the safe-harbour ROSA26 in which the construc