Transcriptomic Profiling of Non-Small Cell Lung Cancer Cell Lines HCC44 and H1792
This study employed RNA sequencing to profile the transcriptomes of two non-small cell lung cancer (NSCLC) cell lines (HCC44 and H1792) treated with FK866, AMG510, and their combination , compared to DMSO control. The aim is to systematically decipher the gene expression changes, altered signaling pathways, and potential synergistic mechanisms induced by the drug combination. This dataset provides a comprehensive resource for understanding the molecular basis of drug interaction and identifying novel therapeutic targets in lung cancer.