16S rRNA gene amplicon sequencing of fecal microbiota in collagen-induced arthritis rats intervened with ethanol extract of Paxillus involutus
This project focuses on exploring the characteristics and changes of fecal microbial community in rats with rheumatoid arthritis (RA). High-throughput 16S rRNA gene amplicon sequencing was used to analyze the fecal microbiota of RA model rats, with five groups (CK, WM, WH, WL, WP) set to compare the differences in intestinal microbial composition among different treatment groups. The raw sequencing data generated in this study have been deposited in the NCBI Sequence Read Archive (SRA) to ensure data accessibility and reproducibility for subsequent related research.