effects of circadian rhythm changes on intestinal flora and gallstone formation (PRJCA044276)
Gallstones are a common digestive disorde. Disruptions in intestinal flora can lead to bile acid and cholesterol metabolism disorders.Circadian rhythms are endogenous mechanisms, playing a vital role in maintaining physiological homeostasis. Disruptions of circadian rhythms significantly affect the abundance and diversity of microbiota in both mice and humans. This study aims to investigate the direct association of circadian rhythm and gallstome formation.