EZH2-GATA6 axis in Pancreatic ductal adenocarcinoma [ChIP-Seq]
We conducted ChIP-seq experiments to investigate the role of EZH2 in Pancreatic ductal adenocarcinoma Overall design: ChIP-seq profiles for EZH2 in NKC cells (mouse PDAC cell line carrying pancreas specific-Kras mutation (KrasG12D) and constitutive activation of NFATc1).ChIP-seq profiles for H3K27me3 and H3K4me3 in NKC cells transfected with shRNA control and shRNA EZH2. Three replicated per condition were analysed.