ncRNA Sequencing facilitates quantitative analysis of differently expressed genes in the peripheral blood mononuclear cells from healthy controls and patients with systemic lupus erythematosus
To further explore the role of long non-coding RNAs in the systemic lupus erythematosus (SLE), we assessed the transcriptome of PBMCs from healthy controls and SLE patients using ncRNA sequencing analysis. The data were analyzed for differential expression with a nominal P<0.05. Our study aimed to discover novel biomarkers for SLE diagnosis and prognosis. Overall design: To detect differently expressed LncRNAs (P<0.05) by ncRNA sequencing in PBMCs from three healthy controls and five SLE patients Definitions: DUIZHAOZU stands for healthy control(HC) or CK BINGRENZU stands for systemic lupus erythematosus(SLE)