In Vivo inhibition of TDO2 in fibroids results in widespread alteration in the tumor transcriptome
This study aimed to characterize large and small RNA transcriptomic changes in fibroid xenografts from mice treated with the TDO2 inhibitor 680C91 for two months. Overall design: Analysis of large and small RNA transcriptomic changes from RNA-seq data in three sets of fibroid xenografts treated with vehicle or the TDO2 inhibitor 680C91 for two months.