Effect of GPRC5B-deficieny on macrophage function [dataset 2]
To investigate whether loss of GPRC5B affects macrophage function, we generated myeloid-specific Gprc5b knockout mice and then did RNA-seq using bone marrow-derived M0 macrophages to analyze the gene expression profile. Overall design: Gene expression profiling in bone marrow-derived M0 macrophages from control mice (LysCre-negative;Gprc5b(fl/fl)) and myeloid-specific Gprc5b knockout mice (LysCre+;Gprc5b(fl/fl)) treated with or without LPS 1µg/ml for 6h (triplicates for each condition).