METTL3-dependent m6A modification programs human neural progenitor cell proliferation [RNA-seq]
To investigate whether the role of METTL3 in hNPCs is dependent on its m6A activity,samples form neural progenitor cell (NPC) differentiation in the small molecule-assisted shut-off (SMASh) tagged hESC groups were collected. Gene expression levels were quantitated by RNA-seq analysis, and the potential target genes were identified by MeRIP-seq analysis and RIP-seq. Overall design: Examination of the potential target genes regulated by the METTL3 in hNPCs.