ASH2L Regulates Postnatal Neurogenesis through Onecut2-mediated Inhibition of TGF-ß Signaling Pathway
We applied whole transcriptome analysis of P7 NSPCs  from WT/Ash2l-iKO mice to gain insight into genes that might be dysregulated and transcriptionally different after Ash2l deletion. Overall design: Total RNA was extracted from the FACS-sorted NSPCs that collected from freshly dissociated P7 cortex Nestin-CreERT2; Ash2lf/f; tdTomato and Nestin-CreERT2; tdTomato mice, in four biological replicates, using Illumina Hiseq4000.