Patulin Impairs Human SVOG Granulosa Cells via ROS-Mediated DNA Damage and ATM-p53 Activation
This study investigates the toxic effects of patulin on human granulosa SVOG cells. Patulin exposure induced ROS accumulation, DNA damage, and activation of the ATM-p53 pathway, leading to G2/M cell-cycle arrest and apoptosis, suggesting potential risks to female reproductive health.