H3K27ac and H3K4me3 ChIP-Seq profiling of a human paired left and right atrial cohort of atrial fibrillation and healthy sinus rhythm individuals
H3K27ac and H3K4me3 ChIP-Seq profiling was performed on atrial appendages samples from 12 individuals aged over 60 years, either classified as persistent atrial fibrillation (AF) or normal sinus rhythm (SR). For all individuals, careful examination of medical history displayed no indications of hypertension, hypothyroidism or diabetes. Overall design: Chromatin immunoprecipitation sequencing (ChIP-seq) for histone postranslational modifications H3K27ac and H3K4me3 in paired left and right atrium from 12 individuals (either classified as sinus rhythm controls or persistent AF). Average age: 71 ± 10.63; Gender (males, females): 11, 1.