mNGS sequencing of clinical vitreous and aqueous humor specimens from suspected fungal endophthalmitis patients
Clinical management of fungal endophthalmitis (FE), a vision-threatening emergency, necessitates expedited causative identification. Conventional culture has low sensitivity, warranting advanced diagnostic approaches. In the study, performance of the unbiased metagenomic next-generation sequencing (mNGS) was evaluated in 31 FE cases, including 16 vitreous and 15 aqueous humor specimens. The raw sequencing data were uploaded.