The effect of Aryl hydrocarbon receptor (AHR) inhibitor CH-223191 on differentiation of human colon organoids
To investigate the effect of AHR deficiency on organoid differentiation or in stem cell state we performed RNA-seq of human colon organoids treated with CH-223191 or DMSO  in stem cell conditions or during differentiation Overall design: We performed gene expression profiling analysis using data obtained from RNA-seq of 3 different control patient organoid lines at day 4 of differentiation or in stem cell state.