Bacterial diversity in the stools of wild type and Pglyrp-deficient mice identified by sequencing of bacterial 16S ribosomal RNA (rRNA) genes.
Intestinal microbiome controls sensitivity to inflammatory bowel disease. Pglyrp-deficient mice are predisposed to colitis and this predisposition is dependent on the changed composition of their intestinal microflora. This project compares the diversity of stool bacteria in wild-type mice and mice deficient in Pglyrp1, Pglyrp2, Plglyrp3, or Pglyrp4 genes.