Topography-Guided Senescent Cell Clearance
To characterize the cellular heterogeneity and transcriptional dynamics underlying diabetic wound repair following A/R-Gel treatment, and to delineate treatment-associated changes in cellular composition, single-cell RNA sequencing (scRNA-seq) was performed using the 10x Genomics platform on wound tissues from control and A/R-Gel treated diabetic mice. These results provide a high-resolution single-cell transcriptional landscape of diabetic wound tissues after biomaterial intervention.