Fluvastatin-perturbed RNA expression in two t(4;14)-positive multiple myeloma cell lines
The goal of this study was to determine the gene expression changes following fluvastatin treatment in t(4;14)-positive multiple myeloma (MM) cell lines. To this end, two cell lines (KMS11 and NCI-H929) were treated with fluvastatin (2 micromolar) or ethanol as a solvent control for 24 hours. RNA was extracted and prepared for high-throughput sequencing in duplicate. Overall design: Two cell lines, each treated with fluvastatin or ethanol as a solvent control (two replicates per treatment condition)