Transcriptome-wide profiling of different mouse adipose tissues during aging using snRNA-seq
We found the mPRAT adipose undergoes a whitning process which differs from iBAT and iWAT. The whitened adipocytes can still respond to cold exposure, which has cellular and molecular differences compared with iBAT and iWAT. Overall design: Different mouse adipose depots including brown and white adipose tissue were collected at different ages for comparison. Besides, the depot-specific cold-response was compared.