Endothelial-specific protein CLEC14A orchestrates osteoblast activity during trabecular bone formation and patterning
RNA sequencing of cells isolated from CLEC14A-/- neonatal pup calvariae reveal enrichment of gene sets related to endochondral ossification and osteoblast maturation along with downregulation of mRNA expression of tight junction, extracellular matrix receptor interaction and cell adhesion molecules.