Targeting BRD4 Ameliorates Experimental Emphysema Via Suppressing both M1 and M2 alveolar macrophage polarization-3
The goal is to find out the bind sites of BRD4, H3K27ac, IRF4 in M2 alveolar macrophages after treatment of BET degraders. Alveolar macrophages were extracted from c57 mice and induced to M2 macrophages using IL-4.