LXR agonism enhances T cell activation upon crosspresentation by LXR-DKO BMDCs.
Here, we analyze transcriptional profiles of OT-I CD8+ T cells co-cultured with LXR-/- bone marrow-derived dendritic cells pulsed with the SIINFEKL peptide in the absence or presence of the synthetic LXR agonist RGX-104. Overall design: Differential gene expression analysis of flow cytometry-sorted OT-I CD8+ T cells after co-culture with LXR-/- bone marrow-derived dendritic cells in the presence or absence of the synthetic LXR agonist RGX-104.