Transcriptomic profile of neutrophils subsets in healthy donors and cancer patients I
We distinguished immature non-suppressive CD45low LDN and mature suppressive CD45high LDN from each other based on their expression of CD45 and CD16 and isolated at least 10,000 cells for each cell type in matched samples from the blood of NSCLC patients, and performed RNA sequencing to determine transcriptomic profile associated with suppression of T cell proliferation Overall design: Comparative gene expression profile of neutrophil subsets from healthy donors and cancer patients