RNA sequencing facilitates quantitative analysis of NPC cells, NPC-KRASG13D, and GSC cells (including U251-GSC, U118MG-GSC) transcriptomes
To investigate the function of KRAS activation in the regulation of neoplastic features, we established NPC-KRASG13D cell lines in which KRAS has been overexpressed. We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells (NPC cells, NPC-KRASG13D, U251-GSC, and U118MG-GSC). Overall design: Comparative gene expression profiling analysis of RNA-seq data for NPC cells, NPC-KRASG13D, U251-GSC, and U118MG-GSC.