Rattus norvegicus Raw sequence reads
ZhuRiHeng Drop Pill (ZRH) is a traditional Mongolian medicinal preparation. Despite its long history of use for the treatment of coronary heart disease, there have been few toxicological studies of the safety profile of ZRH. During the 180-day repeated oral toxicity study, notable alterations in liver ratios were observed in both male and female rats. In order to comprehensively elucidate the underlying mechanisms behind the observed toxicity of ZRH on rat livers, we conducted a comprehensive analysis by integrating transcriptomic and metabolomic data.