Cell cycle duration determines oncogenic transformation capacity
We present single-cell RNA sequencing data of P8 mouse retina with Rb/p107 double knockout (DKO), or Rb/p107 DKO with Skp2+/-. Overall design: Sc RNA-seq of P8 retins of a-Cre; Rbf/f; P107-/- (DKO, tumor-prone) and a-Cre; Rbf/f; P107-/-; Skp2+/- (DKO-Skp2+/-, tumor-resistant) were compared