Profiling of gut microbiota in a murine model of post-inflammatory visceral pain
Gut dysbiosis is a common feature of patients complaining of chronic abdominal pain, including those in remission from inflammatory bowel diseases (IBDs). Although visceral sensitivity in animals can be modulated by faecal microbial transplant (FMT), controversy has emerged in clinical practice, drawing attention to the poor knowledge of the mechanisms which govern host-microbiota crosstalk under pathological conditions. Here we sought to elucidate the mechanisms linking post-inflammatory dysbiosis and pain persistence, to improve the therapeutic outcomes