Single-cell RNA sequencing data of primary and super-charged NK cells
NK cells are essential for mediating host immune responses. Approaches to augmenting the immunosurveillance function of NK cells have been extensively studied. Based on multiple publications, super-charged NK cells have been shown to be successfully activated with enhanced cytokine production and cytotoxicity capabilities. Here we use the single-cell RNA sequencing technique to understand the transcriptomic differences between IL-2 cultured and super-charged NK cells. Our data will help improve our understanding of applying NK cells for immunotherapy. Overall design: Single-cell RNA sequencing analyses of IL-2 cultured and super-charged NK cells derived from the PBMC of healthy donors.