Identification of tumor-related genes via RNA sequencing of tumor tissues in Xenopus tropicalis
Cancer is often caused by mutations in many genes. Although genomic studies have identified many oncogenes and tumor suppressor genes, gene sets involved in tumorigenesis remain poorly understood. Xenopus, a genus of aquatic frogs, is a useful model to identify gene sets because it can be genetically and experimentally analyzed. So we analyzed gene expression in tumor tissues of three individuals in Xenopus tropicalis and compared with that in normal tissues. Overall design: Comparative gene expression profiling analysis of RNA-seq data for tumor tumors and normal tissues of Xenopus tropicalis.