Effect of anti-tumor efficacy of depletion of Nrf2 in effector T cells
To investigate the function of Nrf2-deficient CD8 T cells in the regulation of anti-tumor response, we established adoptive transfer models. We then performed gene expression profiling analysis using data obtained from RNA-seq of Nrf2-deficient and WT CD8 T cells in the tumor. Overall design: Comparative gene expression profiling analysis of RNA-seq data for Nrf2-deficient and WT CD8 T cells in the tumor