RNA sequencing in P1 ovaries exposed to aristolochic acid I
Neonatal ovaries from the control and 0.5 mg/kg AAI group were collected on 1dpp. RNA isolation, library construction, RNA-seq, and standard bioinformatics analysis were carried out by Shanghai Personal Biotechnology Cp., Ltd. The library products underwent sequencing using Next-Generation Sequencing. The significance of differentially expressed genes (DEGs) was determined with |log2[0.5 mg/kg AAI/Control]| > 1 and a P value < 0.05.