H3.3B controls aortic dissection progression by regulating vascular smooth muscle cells phenotypic transition and vascular inflammation.
To investigate the distribution of H3.3B in VSMC phenotypic transition, we infect VSMCs with shNT or shH3f3b virus. Overall design: Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for histone variants H3.3 in primary mouse VSMCs with shNT or shH3f3b.