Genome-wide maps in gastric cancer MKN-45 cells with or without the overexpression of transcriptional factor SIX2
Analysis of MKN-45 cells following SIX2 stable overexpression or not. SIX2 regulates various mRNA expression in MKN-45 cells.Results provide insight into the role of SIX2-involved mechanisms underlying SIX2-mediated effects on gastric cancer stemness. Overall design: mRNA profiles of MKN-45 cells with or without SIX2 overexpression were generated by deep sequencing, in two repeats, using Illumina NovaSeq 6000.