Sequencing of miRNA in exosomes
Fusobacterium nucleatum (Fn) infection is known to exacerbate ulcerative colitis (UC). However, whether Fn can alter the expression profile of miRNAs in normal intestinal epithelial cells (IECs)-derived exosomes and thus regulate the development of UC is unknown. Differentially expressed miRNAs in Fn-infected IECs-derived exosomes (Fn-Exo) and non-infected IECs-derived exosomes (Con-Exo) were identified by miRNA sequencing.