Integrated metagenomic and metabolomic analysis reveals the association  between the maternal gut microbiota and macrosomia in gestational diabetes  mellitus
This study investigates the association between maternal gut microbiota in gestational diabetes mellitus (GDM) and the occurrence of macrosomia. Using metagenomic sequencing, we analyze microbial composition and functional differences among three groups: GDM mothers with macrosomic newborns, GDM mothers with non-macrosomic newborns, and healthy controls (HC). The findings may provide insights into the potential role of gut microbiota in fetal overgrowth under GDM conditions. Notably, maternal gut microbiota samples were collected from pregnant women undergoing cesarean section before delivery.