Single-Cell Transcriptomic Analysis of Orbital Fat in Thyroid-Associated Ophthalmopathy (TAO) Normal People n=4
This dataset contains single-cell transcriptomic analysis of orbital fat tissue samples obtained from three patients diagnosed with Thyroid-Associated Ophthalmopathy (TAO). The study aims to investigate the cellular composition and gene expression profiles of orbital fat in TAO patients, providing insights into the molecular mechanisms underlying this inflammatory autoimmune disease.In this dataset, the cells from orbital fat biopsies were isolated and processed for single-cell RNA sequencing (scRNA-seq) to explore the heterogeneity of the tissue at a single-cell resolution. The analysis reveals distinct cell types and potential cellular interactions that could contribute to the pathogenesis of TAO. This resource is valuable for understanding the complex role of orbital fat in TAO and may help identify novel therapeutic targets for managing this condition.The samples were collected from three independent TAO patients, and rigorous quality control procedures were applied to ensure the reliability and reproducibility of the data. This dataset can be used for further comparative studies with healthy controls or other related autoimmune disorders.