DEG and microRNA signatures from HFpEF ventricular biopsies.
Heart Failure with Preserved Ejection Fraction (HFpEF) represents a global health challenge, with limited therapies proven to enhance patient outcomes. The substantial heterogeneity among HFpEF patients could be a significant factor contributing to the ongoing challenges in effectively treating the disease. Therefore, an improved understanding of the different HFpEF phenotypes might elucidate the underlying mechanism of disease and help in the development of effective therapeutic approaches. Here, we report the DEG and microRNA data from patients with HFpEF and controls, prospecting to discover distinctive transcriptomic signatures.