Impact of intestinal microbiota on host health and disease
The intestinal microbiome has a range of effects on host health and disease. Many physiological processes are influenced by the intestinal microbiota. In turn, changes in bacterial composition have been suspected to contribute to the development of multiple disorders. This study analyzes how the composition of intestinal microbiota influences the whole organism including host metabolism, physiology and immune system. Here, we compared the composition of intestinal microbiota between gnotobiotic mice associated with the Oligo-Mouse-Microbiota 12 and mice carrying a complex gut microbiota (SPF hygienic status).