The effect of Regnase-1 on gut microbes
As ApcMin/+ mice with Regnase-1 (Reg1) deletion specifically in intestinal epitheluim (Reg1KO-Min) had increased expression of antimicrobial peptides compared to control ApcMin/+ mice with wild-type Reg1 (Reg1WT-Min), we explored the effect of Regnase-1 deletion on gut microbes by metagenome analysis of fecal samples from Reg1WT-Min mice and Reg1KO-Min mice.