Gene expression profile at single cell level of conditional senescence in mouse Emu-myc B-cell lymphoma model
Based on the senescence switch Suv39h1, the same lymphoma population enters senescence (TIS) or non-senescence (non-TIS) status. Overall design: Lymohoma cells are exposed to ADR ± 4-OHT to enter non-TIS or TIS status for scRNAseq analysis.