Generation of mandibular prominence ectomesenchyme (mdEM) from human induced pluripotent stem cell (iPSC)-derived neural crest cell (NCC) aggregates
To clarify the changes in cell properties during the differentiation process from iPSCs into mdEM through NCC aggregates, we sampled iPSCs and cell aggregates during the differentiation process and compared gene expression patterns. Overall design: RNA sequencing profiles of 1231A3 iPSCs, NCC aggregates (day 5), and mdEM (day 9).