Genomic localization of ENL and DOT1L in HEK293T cells deficient for MOZ
To elucidate the role of MOZ in the genomic localization of ENL and DOT1L, we generated HEK293T cells  lacking the both alleles of MOZ by CRISPR-cas9 technologies. HEK293T cells deficient for MOZ were analyzed using ChIP-seq technologies with anti-ENL and DOT1L antibodies. For comparison, the parental HEK293T cells were also anlyzed along side.