Dose-dependent transcriptomic response to DEHP exposure in rat thyroid
Transcriptomic profiling was done to find carcinogenic mechanism of di-2-ethylhexyl phthalate (DEHP) in rat thyroid. Rats were treated with different doses of DEHP (0, 0.3, 3, 30, 150 mg DEHP/kg/bw/day) for 13 weeks. Then, the thyroids were processed with RNA-Seq. Some cancer-related genes showed altered expression.