Single-cell RNA sequencing of PBMC with and without LILRB3-4SNPs pretransplant and posttransplant
Single-cell RNA sequencing were conducted on PBMCs from patients with and without LILRB3-4SNPs risk allele to evaluate the potential effects of this SNP on cell level. Overall design: Single-cell RNA sequencing were performed on PBMCs isolated from the pretransplant blood of 2 AA recipients (1 with and 1 without LILRB3-4SNPs) and post-transplant (24 months) blood of 2 AA recipients (1 with and 1 without LILRB3-4SNPs) with matched recipient and donor's demographic and baseline clinical features (age, gender, donor status, HLA mismatches and induction types).