Targeting ACER3 Attenuates Cholestasis by Mitigating Bile Acid Overload via Unsaturated Ceramide-mediated LXRbeta Signaling Transduction
This study investigates the function of alkaline ceramidase 3 (ACER3)-catalyzed hydrolysis of unsaturated CERs in CLI. This data are the RNA sequencing of liver tissues in female WT mice and Acer3 KO mice under sham operation.