Analysis of intestinal microbiome in DSS-treated C57BL/6J and Vil1-AhR KO mice
Three-week-old C57BL/6J (WT) mice and villincre Ahrfl/fl mice (KO) on C57BL/6J background were provided with diets with one of three zinc concentrations (5 mg/kg (Zinc5), 35 mg/kg (Zinc35) and 100 mg/kg (Zinc100) from Days 0-10 with (I3C) or without (ddH2O) I3C given by daily gavage. DSS was administered by the drinking water from Day 4 to Day10. Mice were sacrificed on Day 11 and intestinal contents sampled for microbiome profiling.