TOX drives TH1 CD4+ T cell effector function, anti-tumor immunity, and pathogenicity in autoimmune diseases [CUT&RUN]
CUT&RUN analysis of CD4 and CD8 T cells (confirmed to express TOX) Overall design: WT congenic (Ly5.1) CD4+ TCRSMARTA (transferred into B16-GP61 tumor hosts) or CD8+ (Ly5.1) TCRTAG (transferred into liver tumor-bearing ASTxAlbCre hosts) were isolated and sorted from tdLN and liver tumors, respectively, and subjected to CUT&RUN