Sequencing of Autologous fecal microbiota transplantation in mice.
At present, most FMT procedures involve heterologous transplantation, with aFMT only utilized to restore intestinal microecology following antibiotic exposure. However, hFMT carries certain risks, such as pathogen transmission and infection by opportunistic bacteria, while donor-recipient matching systems also remain suboptimal. In contrast, aFMT offers several advantages over hFMT, including a reduced risk of inflammatory responses in recipients due to better intestinal immunological compatibility and increased safety.