Effect of norepinephrine and/or propranolol on fallopian tube epithelial cells in ultra-low attachment conditions
To investigate the role of norepinephrine on 3D spheroid formation and survival in early high-grade serous ovarian cancer, we cultured immortalized human fallopian tube epithelial cell lines in ultra-low attachment conditions in the presence or absence of norepinephrine and/or propranolol over 2 different timepoints. Overall design: Comparative gene expression profiling analysis of RNA-seq data for FT237 and FT246 cultured under ultra-low attachment conditions for 4 or 24 hours, -/+ norepinephrine and/or propranolol