Effect of HAPLN1-PTR1 on STAT1 knockout RPMI8226 multiple myeloma cells
To identify the HAPLN1-induced genes regulated by STAT1 in multiple myeloma, we treated RPMI8226 multiple myeloma cells (WT or STAT1 KO) with recominant HAPLN1-PTR1. We then performed gene expression profiling analysis using data obtained from RNA-seq. Overall design: Comparative gene expression profiling analysis of RNA-seq data for RPMI8226 multiple myeloma cells (WT or STAT1 KO) treated with 100 nM MBP (control) or MBP-PTR1 (experimental group) for 6 h.