The effect of KIF11 knockdown on gene expression profile in HepG2 cells
High-throughput sequencing is performed to identify the genes whose expression levels were altered when KIF11 is downregulated by lentiviruses-mediated shRNA in HepG2 cells. Overall design: The expression of KIF11 was knocked down by lentiviruses-mediated shRNA in HepG2. The control and KIF11-deficient HepG2 cells were subjected to High-throughput sequencing and mRNA expression profile data analyzing.