U-87 MG Temozolomide-Induced Senescence RNA-seq Dataset
We analyzed the U-87 MG cell line, which was treated with temozolomide for 5 days to induce a senescent state. The study aimed to investigate molecular and phenotypic alterations associated with senescence in the context of a malignant phenotype. Senescence was confirmed through ß-galactosidase staining (SA-ß-gal), assessment of growth arrest, p21 expression and lipofuscin autofluorescence. Due to inconsistency in paired-end read files, only forward (read1) sequences were retained and submitted as single-end data.