Gene expression profiles of lung tumor cells in relapsed mouse tumors after anti-PD1 treatment
We employed subcutaneous 889S1 lung tumor model with a short-duration anti-PD-1 therapy and then performed RNA-seq analysis of FACS-isolated tdTomato+ tumor cells from tumors to evaluate the transcriptomic alteration between the regrown tumors after anti-PD-1 treatment and IgG-treated control tumors.