Gene expression profile at single cell level of CD45+ cells isolated from twitcher (twi) mouse brain (postnatal day 21)
Gene expression profile at single cell level of CD45+ cells isolated from wildtype (twi littermate) mouse brain (postnatal day 21) to evaluate and compare differences in immune cells at the onset of spontaneous clinical disease in a mouse model of globoid cell leukodystrophy. Overall design: CD45+ cells were isolated from single cell suspension of hemi-brain tissues by positive selection using flow cytometery