RNA-seq Analysis of Anti-PD-L1 Treated 4T1 Tumors in BALB/c Mice
This study investigates the transcriptomic changes in 4T1 tumors with PD-L1 overexpression compared to control 4T1 tumors. Tumors were injected into the mammary fat pad of BALB/c mice, followed by treatment with IgG or anti-PD-L1 antibodies. After tumor growth observation, RNA sequencing was performed.