Tsc2 coordinates differentiation [scRNA-seq]
Multipotent neural stem cells (NSCs) that reside within the ventricular-subventricular zone (V-SVZ) of the brain generate a variety of cell types. Here we provide transcriptomes of cells that have lost Tsc2 as occurs in the neurodevelopmental disorder Tuberous Sclerosis Complex (TSC). Overall design: Single nuclei sequencing of wild-type and Tsc2 mutant mouse