Bulk RNA-seq of co-cultured SCC25 and mouse or naked mole-rat fibroblasts
Mice are cancer-prone, whereas naked mole-rats are cancer-resistant. Because fibroblasts support the development of skin cancer, SCC25 cells were co-cultured with either mouse or naked-mole rat cells and the difference in SCC25 cells grown alone or with the different types of fibroblasts were compared. Cells were grown together for two days, then FACS-sorted and bulk-sequenced separately.