Huangqin and Huanglian Combination improves T2DM by affecting the intestinal microbiome and increasing fecal short-chain fatty acid content in mice
Huangqin and Huanglian are commonly used herbal combinations for the treatment of type 2 diabetes mellitus (T2DM), but the mechanism of the effect of their treatments on the gut microbiome has not been thoroughly investigated. In this study, we observed changes in the intestinal microbiome of mice by dosing normal mice with Huangqin or Huanglian and T2DM model mice with the Huangqin and Huanglian combination, respectively. The HQ and HL groups were Huangqin and Huanglian infused normal mice, respectively.T2DM mice were infused with Huangqin and Huanglian Combination at the time of TCM group.