Crnic Institute Human Trisome Project - Trisomy 21 Model Atlas: PolyA RNA-seq from human iPSC-derived Hepatocyte-like cells
Analysis of steady-state mRNA levels in Hepatocyte-like cells differentiated from human iPSCs originating from donors with and without Down syndrome. This dataset is part of the Human Trisome Project - Trisomy 21 Model Atlas run by the Linda Crnic Institute for Down Syndrome at the University of Colorado Anschutz Medical Campus. http://www.trisome.org/ Overall design: Hepatocyte-like cells differentiated from a panel of iPSCs reprogrammed from urine-derived kidney epithelial cells of human donors - comparison of cells with trisomy 21 (T21, n = 6) to euploid controls (D21, n = 6).