Mapinsights : advanced quality assessment for high-throughput sequencing data
Terabyte scale data generated on today's fast and cheap high-throughput sequencing technology often came with random errors and unwanted biases.It is very crucial to detect these errors and biases which might have an effect on downstream analysis. Several attempts were made in this regard mainly focusing on standard quality-control (QC) metrics such as GC content, base composition, mapping quality etc but none of these algorithms put systematic attention on sequence read mismatches with respect to reference genome in greater depth. We have developed Mapinsights, a command-line tool that perform quality assesment of aligned data.