Association between gut microbiota and CpG island methylator phenotype in colorectal cancer [DREAM]
We report the association between CpG islander methylator phenotype (CIMP) and the gut microbiome in human colorectal cancer tumor and adjacent normal tissue. Overall design: DNA was isolated from human colorectal cancer tumor and adjacent normal tissue samples and performed Digital Restriction Enzyme Analysis of Methylation (DREAM) for methylation profiling.