Probiotic treatment in Psoriatic Arthritis Raw sequence reads
This study investigated whether a multispecies probiotic could influence disease activity, gut permeability, immune profiles, or microbiome composition in individuals with psoriatic arthritis, aiming to evaluate the therapeutic relevance of targeting the gut microbiome. Psoriatic arthritis has been linked to alterations in gut microbial balance, making probiotics a potential adjunctive therapy. However, in this study the probiotic did not demonstrate any clinical or biological benefit compared with placebo. Based on these findings, the probiotic mixture studied should not be considered for adjunctive treatment in PsA. Sequencing was performed at the Joint Microbiome Facility of the Medical University of Vienna and the University of Vienna under the project ID JMF-2212-15.