in vivo comparable transcriptome profiles of chemicals in mouse liver
The aim of this study is to establish diverse and comparable models of liver dysfunction by utilizing the characteristics of low molecular weight compounds, in order to provide tools and knowledge that contribute to the understanding of the progression of liver dysfunction. The prepared chemicals are acetaminophen, alpha naphthyl isothiocyanate, CCl4, concanavalin A, galactosamine, methylene dilaniline, and thioacetamide.