Effect of site directed mutagenesis on transcriptomic difference between A549 (T/T) and A549 (C/C) cells
To study the effect of rs1663689 on lung cancer cells, we generated A549(C/C) from A549(T/T) using CRISPR/Cas9 technology and performed RNA-seq. Overall design: Comparative gene expression profiling analysis of RNA-seq data for A549(T/T) and A549(C/C) cells