Healthy aging of skeletal muscle: Insights from a combined morphological and multiomic study
This study shows age-related differences in the molecular signatures of healthy skeletal muscle. Moreover, the findings assert that processes previously associated solely with aging and sarcopenia are indeed part of healthy aging. Additionally, the data underscores the importance of using appropriate age-matched controls for multi-omic molecular profiling of muscular disorders. Overall design: Comparative age related transcriptomic analysis of human skeletal muscle samples