Pediatric leukemia disease progression
This is a study of paired initial diagnostic and relapse or paired relapse-relapse pediatric acute lymphoblastic leukemia bone marrow biopsies. The goal of this study was to compare the transcriptomes of paired samples from the same patient to investigate stable or divergent processes through disease progression. Transcriptome data was sequenced on an Ion Torrent S5 and processed with the AmpliSeqRNA plugin. Libraries were prepared on the Ion Chef with the Ion AmpliSeq Transcriptome Human Gene Expression kit.