Lactobacillus acidophilus Transcriptome or Gene expression
This study determines how structurally diverse dietary polyphenols modulate the physiology of Lactobacillus acidophilus ATCC 4356 across multiple molecular layers, with emphasis on transcriptional programs and the role of N4-methylcytosine (4mC) in diet-responsive epigenetic regulation. It defines compound-specific regulatory fingerprints and links epigenetic changes to carbohydrate metabolism, stress responses, and adhesion traits relevant to probiotic function.