Next Generation Sequencing Facilitates Quantitative Analysis of SPS and Control Rats Model
In the present study, we used the single prolonged stress (SPS) model to mimic  posttraumatic stress disorder. High-throughput sequencing were utilized to analyze differentially  expressed genes (DEGs) in the hippocampus of control and SPS rats. RNA-seq analysis revealed 230 significantly DEGs between  the control and SPS groups. Overall design: mRNA profiles of single prolonged stress (SPS) and control rats model