Critical Role of Runx Transcription Factors in Maintaining Epididymal Epithelial Differentiation [RNA-seq II]
To study the role of RUNX transcription factors in the epididymal epithelial cells we deleted Runt domains of Runx1 and Runx2 from mouse epididymal cell line mE-Cap18 using CRISPR-Cas9 technique. Overall design: RNA-seq was performed from 3D organoids from Control and Runx-deletion cell lines.