Metabolic Changes and Microbial shifts Following Cholangiocarcinoma-derived Fecal Microbiota Transplant and Bile Reinfusion in Wistar rats
In this study, we performed CCA-derived fecal microbiota transplantation (FMT) and bile reinfusion (BR) in Wistar rats, and we employed nuclear magnetic resonance (NMR) based metabolomics and 16S rRNA gene sequencing based microbiomes to enhance the comprehension of host-microbiota interaction in CCA and after BR.