Transcriptome analysis upon lymphatic endothelial cells (LEC) and cancer cells (Haca4) co-culture
To investigate the mechanisms underlying the connection between LEC and cancer cells and their potential roles in tumorigenesis we co-cultured LEC and HaCa4 cells for 24 hours and compared the transcript levels of both FACS-isolated HaCa4 cells and LEC from co-cultures with those from individual cell cultures Overall design: Comparative gene expression profiling analysis of RNA-seq data for LEC and HaCa4 cells and FACS-sorted HaCa4 cells and LEC after 24 hours co-culture