Whole transcriptome sequencing of lung tissue from septic mice
Acute lung injury (ALI) is a common complication of sepsis, which can progress to acute respiratory failure without timely intervention and affect patient prognosis. The underlying molecular mechanism of sepsis-mediated ALI is unclear. In the present study, we performed whole-transcriptome sequencing and identified a lncRNA/circRNA-miRNA-mRNA ceRNA network and signaling pathways to gain insight into the pathogenesis of ALI..