Transcriptomic analysis of colonic tissues from anti-CD40-induced murine colitis treated with anti-DNAM-1 or anti-TNF antibodies
This BioProject contains bulk RNA-seq data generated from colonic tissues of mice with anti-CD40 monoclonal antibody-induced colitis. The dataset includes colon samples from treatment groups receiving control antibody, anti-DNAM-1 antibody, or anti-TNF antibody, and was generated to compare inflammatory transcriptional programs associated with DNAM-1 blockade and TNF inhibition in murine intestinal inflammation.