The novel RNA binding protein ZCCHC24 regulates cancer stemness of breast cancer
With scRNAseq for PDX, we identified ZCCHC24 as the unknown RNA binding protein regulating the cancer stemness of breast cancer. Transcriptome analysis, Dyrec-Seq analysis, and PAR-CLIP analysis showed that ZCCHC24 bound to certain cis-elements in 3'UTR of genes related to breast cancer stemness, and stabilized them. In these datasets, the sequenced data were uploaded.