Transcriptomic analysis of APC knock down HCEC 1CT cells compared to the wild type HCEC 1CT cells.
In order to investigate sophisticated events during cancer initiation, we established early colorectal cancer development model. We performed scRNA-seq and analyzed the scRNA-seq dataset. scRNA-seq was conducted at 3- and 7-days after transduction of shRNA targeting APC (shAPC) and scrambled shRNA (shScr) on HCEC 1CT cells. Overall design: scRNA-Seq of the shScr and shAPC cell lines in hCEC 1CT cells