HINT1 Aggravates Aortic Aneurysm by Targeting ITGA6/FAK Axis in Vascular Smooth Muscle Cells
We analyzed differentially expressed genes in mouse aortic smooth muscle cells (MASMCs)  from wild-type or Hint1-/- mice treated with 20ng/ml PDGF-BB for 24h to explore the mechanism that HINT1 triggers VSMC phenotypic switching. Overall design: Identification of differentially expressed genes in MASMCs from wild-type or Hint1-/- mice treated with 20ng/ml PDGF-BB for 24h (n=4 per group).