Characterization of Gut Microbiome Dysbiosis in Calcium Oxalate Stone Patients with Comorbid Metabolic Syndrome
Metabolic syndrome is an important risk factor for calcium oxalate stone, but the underlying mechanisms are unclear, and intestinal flora is associated with both. In this study, 100 subjects were divided into calcium oxalate stone combined with metabolic syndrome group, simple metabolic syndrome group, simple calcium oxalate stone group and healthy control group, 25 cases in each group, and the composition and function of intestinal flora were analyzed by 16S rRNA gene sequencing, and changes in flora were evaluated by combining with the clinical parameters and the annotation of KEGG metabolic pathway.