RNA-Seq analysis of HCV-related HCC and NBNC-HCC tumor and non-tumor part gene analysis
We performed RNA-seq analysisfor 2 HCV-HCC and 3 NBNC-HCC tumor and non-tumor regions, total for 10 samples to find the lncRNAs candidates in HCV-related HCC. Overall design: To identify lncRNAs relevant to HCV-HCC in a screening set, we first determined significantly differentially expressed (SDE) lncRNAs with a >2-fold change (p < 0.05) between (A) T vs. ANT in HCV-HCC considered to be relevant to HCV-related carcinogenesis; (B) T vs. ANT in NBNC-HCC considered to be relevant to non-HCV-related carcinogenesis; (C) HCV-ANT vs. NBNC-ANT tissues considered to be relevant to HCV-related non-oncogenic effects; and (D) HCV T vs. NBNC T tissues considered to be relevant to HCV-related carcinogenesis.