Genetic and epigenetic variations underpin rapid adaptation of oyster populations (Crassostrea gigas) to Pacific Oyster Mortality Syndrome (POMS)
In this study, we used a combination of whole exome capture of bisulfite converted DNA, next-generation sequencing and a various statistical approach to reveal that natural oyster populations differentially exposed to POMS display signatures of selection both in their genome (i.e. single nucleotide polymorphism) and epigenome (i.e. DNA methylation in the CG context).