Transcriptomics reveals molecular differences in equine oocytes vitrified before and after in vitro maturation
The aim of this study was to analyze transcriptome profiles with RNA sequencing (RNA-seq) in metaphase II horse oocytes after vitrification before and after in vitro maturation (IVM). To do so, transcriptome profile of three groups were compared: (1) oocytes vitrified immature, warmed, and in vitro matured (VGV), (2) in vitro matured and vitrified (VMAT), and (3) fresh oocytes (CONTROL). Overall design: Examining the effects vitrification before and after in vitro maturation  on the transcriptomic level of the mature oocyte.