Role of Osgep in modulating proinsulin translation in pancreatic beta cell
To determine the role of Osgep in beta cell function, we generated beta cell specific Osgep knockout mice and assessed their glucose homeostasis, islet morphology, and gene expression. For the RNA-seq analysis, islets were collected from male Osgep-Ins2-Cre mice and littermate control mice (N = 3).