HNF1amaintains pancreatica and ß cell functionsin primary human islets [CUT&RUN]
HNF1a genome-binding profiling by CUT&RUN and high-throughput sequencing. Overall design: We analyzed the genomic targets of HNF1a by HNF1A-FLAG overexpression in primary human pseudoislets and CUT&RUN, comparing anti-Flag antibody to anti-IgG control for each donor.