Heat-Killed Enterococcus faecium FBL1 Attenuates Parkinson's Disease via Modulation of Inflammation and alpha-Synuclein
Gut and brain crosstalk in PD pathogenesis is significantly influenced by gut microbial dysbiosis and the resulting changes in bacterial metabolite activity. The present study investigated whether specific bacterial taxa could alter the gut microbiota to maintain homeostasis and play a protective role against neurological diseases by modulating the inflammatory responses, apoptotic pathways, and MAPK signaling.