Defective mitochondrial dynamics underlie manganese-induced neurotoxicity
Rats were exposed to manganese (Mn) at 25mg/kg for 15 days. After the exposure, the RNA was collected from the striatum tissue (specific part the brain) of the control group (untreated) and Mn-exposed group, and submitted for RNA sequencing to elucidate the transcriptional changes of Mn-induced toxicity in the striatum. Overall design: Examination of the transcriptomic profile of striatum exposed to Mn.