Spatially resolved transcriptomics analysis deciphers intra-tumoral heterogeneity and associated molecular characteristics of small cell lung cancer
The study population consisted of 25 patients (79 ROIs) who were treatment naive, resected and pathologically confirmed limited-stage SCLC (LS-SCLC) and were recruited between 2009 to 2016 from the archival electronic medical record system (EMRS) at the Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences (CHCAMS).