Temporal variability of phenotypic traits of microorganisms isolated from burn wounds
The project involves sequencing the genomes of bacteria isolated from burn wounds. The aim is to characterize isolates obtained three times over a six-day treatment period. Genetic analysis includes determining phylogenetic relationships between isolates of the same species at different time points and identifying any differences, particularly in the sets of genes encoding resistance to antimicrobial agents and virulence factors related to movement, adhesion, and biofilm formation. The species composition of the isolates includes Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis.