Palbociclib releases the latent differentiation capacity of neuroblastoma cells [H3K27ac ChIP-seq PB and RA]
We have used H3K27ac ChIP-seq to assess the global impact of the combination of palbociclib and retinoic acid on the epigenetic H3K27ac landscape in three neuroblastoma cell lines. Overall design: H3K27ac ChIP-seq in SK-N-BE(2)C cells following DMSO, RA, PB or PB+RA treatment for 5 days