Effect of inhibition of Setdb1 on gene expression in AML12 cells
To investigate the mRNA expression regulated by Setdb1, we established  AML12 knockdown cell model by infecting Setdb1 siRNA for 72 hours Overall design: We then performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cell groups (siNC vs siSetdb1, 3 samples per group).