Gene expression profile of MANF-deficient Cx3cr1+ macrophages during muscle regeneration
RNA sequencing analysis of MANF-deficient macrophages revealed changes in key cellular processes. Overall design: CD45posF4/80pos macrophages were FACS-isolated from BaCl2-injured skeletal muscles at 3 days post injury. MANF deficiency was induced by tamoxifen treatment of Cx3cr1-CreER, Manffl/fl mice and compared with oil treated mice of the same genotype.