rat gut metagenome Targeted loci environmental
This project contains 16S rRNA amplicon sequencing data of fecal samples from a collagen-induced arthritis (CIA) rat model. The study aims to investigate the therapeutic mechanisms of Bo's Abdominal Acupuncture (BAA) on rheumatoid arthritis (RA). Specifically, it explores how BAA remodels the gut microbiota and modulates the gut microbiota-metabolite-immune axis to correct the Th17/Treg immune imbalance. The sequencing data is used to clarify the role of intestinal microecology in the systemic anti-arthritic effects of BAA.