Genomic analysis of A. calcoaceticus baumannii isolates retrieved from colombian hospital in the 2020 - 2021 period
Acinetobacter baumannii is a relevant opportunistic pathogen due to its ability to cause serious infections and acquire antimicrobial resistance. In Colombia, there are insufficient reports showing the behavior of this pathogen at a regional level. The use and analysis of genomic data is a key tool for understanding the distribution and transmission of pathogens of public health concern, enabling the development of prevention strategies and the reduction of antimicrobial resistance (AMR). Based on this, a study was conducted that included 89 strains from hospitalized patients between 2020 and 2021. Using whole-genome sequencing data from these isolates, epidemiologically relevant groups were identified, as well as resistance and virulence genes that reveal the local behavior of A. baumannii. This study allows for the identification of the main variables behind the distribution of a critical pathogen that has been understudied in the country.