Unveiling the Mechanism of Broad-Spectrum Blast Resistance in Rice: The Collaborative Role of Transcription Factor OsGRAS30 and Histone Deacetylase OsHDAC1 (PRJCA019002)
OsGRAS30, which genetically acts upstream of OsHDAC1 and interacts with OsHDAC1 to suppress its enzymatic activity. This inhibition increases the histone H3K27ac level, thereby boosting broad-spectrum blast resistance. Integrating genome-wide mapping of OsHDAC1 and H3K27ac targets with RNA sequencing analysis unveils how OsHDAC1 suppresses the expression of LRR genes to regulate blast resistance.