scRNA-seq profiling of SIV Gag-specific follicular CD8 T cells in lymph node of SIV-infected cynomolgus macaques.
To characterize the SIVmac239 Gag-specific fCD8 T cells in lymph node, we performed scRNA-seq analysis of activation-induced markers (AIMs)-positive CXCR5-positive fCD8 T cells from various stages (progressors and natural controllers) or conditions (before treatment, after treatment and post treatment interruption) of SIV-infected cynomolgus macaques.