Isolation of lytic bacteriophage vB_Fpr_FP01
In this study, we report the isolation and characterization of the first lytic F. prausnitzii bacteriophage, vB_Fpr_FP01. Whole genome sequencing and comparative genomics were conducted and uncovered that this phage resides in the human gastrointestinal tract and represents a novel genus within the Caudovirales family. Further isolation and characterisation of novel F. prausnitzii phages is essential, to not only contribute to the growing phage databases, but also for further investigation into phage-host interactions and the impact on the gut microbiota.