DNA methylation profiling of zebrafish DNMT3aa and DNMT3ab mutants
Zebrafish embryos from the wildtype, dnmt3aa, dnmt3ab and double knockout (dnmt3aa, dnmt3ab) homozygous fish were collected at 10 hours post-fertilization and sampled for Reduced Representation Bisulfite Sequencing (RRBS). Overall design: 10hpf embryos from four different genotypes were sampled and sequenced for RRBS profiling. Each genotype had 5 biological replicates with 20 embryos per replicate.