Homo sapiens Transcriptome or Gene expression
Transcriptome sequencing was conducted on the human pancreatic cancer cell line BXPC-3 transfected with lentivirus carrying either KRAS WT or KRAS G12D mutation. This study aimed to explore the molecular mechanisms underlying the effects of these mutations on gene expression profiles and cellular processes. The results provide insights into how KRAS G12D mutations may regulate cellular contribute to tumor progression in pancreatic cancer