The effect of K458R mutation of HNF4A on HCC
To investigate the inhibitory effect of K458R mutation of HNF4A on HCC, we established Huh-7 xenografts treated with Ad-GFP, Ad-HNF4A or Ad-K458R. We then performed gene expression profiling analysis using data obtained from RNA-seq of three groups of  Huh-7 xenografts treated with adenovirus. Overall design: Comparative gene expression profiling analysis of RNA-seq data for Huh-7 xenografts treated with Ad-GFP, Ad-HNF4A or Ad-K458R.