0.06% Chlorhexidine and salivary microbiota study
This study investigates the long-term ecological impact of 0.06% chlorhexidine (CHX) toothpaste on the salivary microbiota of healthy individuals. Using 16S rRNA gene sequencing (V3–V4 region), we characterized taxonomic and predicted functional shifts across three time points: baseline, 12-week intervention, and 12-week washout. The data set consists of amplicon sequences aimed at evaluating the stability of salivary microbiota and the prevalence of predicted antimicrobial resistance genes during and after prolonged CHX exposure.