Aggregation as a distinct phenotype in gut-associated bacteria from critically ill patients
This study describes aggregation phenotypes in bacterial isolates obtained from stool samples of critically ill patients. Aggregation was prevalent and highly strain-specific. The influence of bile acids on aggregation behaviour was assessed, demonstrating environmental responsiveness. Aggregation was further analysed in relation to biofilm formation, growth rate, and antibiotic susceptibility, indicating that it represents a distinct phenotype. These data provide insight into microbial behaviour and organisation in the human gut.