Obesity-related T cell dysfunction impairs immunosurveilance and increases cancer risk
The current study used a mouse model of diet-induced obesity to investigate tumor-infiltrating CD8+ T cell responses. Overall design: Tumors from lean or obese C57Bl/6J mice were harvested and CD8 T cells were isolated by CD8 (TIL) mouse magnetic Microbeads (Miltenyi) and Flurescence-activated cell sorting.