Multi-omics profiling of mouse myocardial infarction
Myocardial infarction (MI),  the most severe manifestation of coronary artery disease, is a multifactorial pathophysiologic process. Here, we constructed a MI mouse model through ligation of the proximal left anterior descending coronary artery. Then we detected and analysed  multi-omics (transcriptome and proteome) at different time points (Control, 10 mininte, 1 hour, 6 hour, 24 hour and 72 hour) after MI. Immune-related pathway, pyroptosis pathway, and autophagy pathway r were significantly increased after MI. Overall design: RNA-seq analysis of mouse myocardial infarction at different time points (Control, 10 mininte, 1 hour, 6 hour, 24 hour and 72 hour) after MI.