Blood Transcriptomics Implicate Epigenetics in the Acquisition of Disease Tolerance to Malaria
To determine how blood transcriptomics are differentially regulated during symptomatic malaria versus asymptomatic parasitemia. Overall design: Whole-blood samples from Ugandan children were analyzed by RNAseq. In most cases, samples are paired, and children were sampled when they were uninfected and also when they had either symptomatic malaria or asymptomatic parasitemia.