Cas9 Nickase-mediated contraction of CAG/CTG repeats is transcription-dependent but replication-independent
Long-read sequencing (PacBio) data from HEK293-derived GNickS12, GNickS115, and GNick102 cell lines before or after treament with doxycycline or DMSO for 26 days. The cells lines all constitutively express the Cas9 D10A nickase with GNickS12 and GNickS115 also expressing a sgRNA targeting CAG/CTG repeats.