Skin tissue sequencing of rat photoaging model
Construct an animal model of photoaging skin in SD rats, extract gene differences in tissue exosomes from photoaging and normal tissues, and use differential mRNA as a new target. Amplify the differential mRNA using PCR technology to obtain a certain amount of differential mRNA. At the cellular level, knock on the gene to obtain the target gene for photoaging treatment. Use Western blot and PCR techniques to observe changes in signaling pathway proteins. Provide more evidence for clinical translation and the safety and effectiveness of treatment