The effect of LAIR-1 ligation on naïve CD8 T cells
To assess the role of LAIR-1 signalling on CD3 stimulated CD8 T cells, we ligated LAIR-1 on CD8 T cells during CD3 mediated CD8 T cell stimulation Overall design: naïve CD8 T cells were isolated and cultured for 6 hours in the presence of anti-CD3, or corresponding isotype antibody, and anti-LAIR-1 (or isotype control)