A diarrhoea surveillance study in children uner five years in Lusaka, Zambia
Shigella is a genus of Gram-negative bacteria responsible for causing shigellosis, a highly infectious diarrheal disease. Shigella species are classified into four groups (S. dysenteriae, S. flexneri, S. boydii, and S. sonnei) and exhibit significant genetic variability, which contributes to their pathogenicity and antibiotic resistance profiles. Whole-genome sequencing (WGS) of Shigella isolates provides crucial insights into the genomic features that underpin virulence, transmission dynamics, and resistance mechanisms.