Comparative genomic analysis of post-pandemic 2022-2023 influenza A in Canada
This study applies comparative WGS to H3N2 viruses circulating in Canada during the 2022-2023 influenza season, integrating concatenated pseudogenome analysis with amino acid substitution profiling to enhance genomic surveillance resolution. The combined genomic and phenotypic findings strengthen influenza surveillance and provide stronger evidence to support antiviral use assessments and vaccine strain selection.