Aristolochic Acid Nephropathy 2 week time point of CD45+ cells
An evolutionarily conserved kidney resident macrophage phenotype defined by reduced MHCII expression universally appears after acute and chronic kidney injury To investigate transcriptional and spatial differences in the MHC II negative kidney resident subpopualtion after CKD Overall design: Single cell RNA sequencing and spatial transcriptomic analysis to identify and visualize MHC II- kideny resident macrophages and CD4+ T cells, scRNAseq samples were hashed