Transcriptomic differences between radioresistant 4T1 and parental 4T1
A radioresistant 4T1 cell line, a mouse TNBC cell lines, was developed by giving a total dose of 50Gy (2gyx5, 4Gyx3, 6Gyx3, and 10Gyx1) to the parental cell line. The trancriptomic changes that occur include enhanced antioxidant response, increase in DNA repair pathways, and invasion/metastasis features. Overall design: RNA-seq of 4T1 radioresistant vs parental cell lines