CDK1 regulation of P53 phosphorylation mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis from the Xinjiang region, China
THP-1 Macrophages were infected with Mycobacterium tuberculosis clinical isolates from Xinjiang, China, and H37Rv for 24 hours, respectively, and their transcriptomes were sequenced to investigate the specific biological processes that occur after infection of macrophages with Mycobacterium tuberculosis clinical isolates from Xinjiang, China. Overall design: L3-L6 are samples of macrophages infected with clinical isolates of Mycobacterium tuberculosis from Xinjiang, China;V1-V3 are samples of macrophages infected with H37Rv;C1-C3 are samples of macrophages not infected with any tuberculosis