Individual RNA-seq for different prostate cancer cells, tumors treated by LGK974, ENZ, EPZ6438, EED226 or by CTNNB1 gene knockdown and overexpression, and BRN2 gene knockdown
Gene expression profile of different prostate cancer clinical tumors and adjacent normal tissue, PDX tumor, and cell models to study the tumor lineage plasticity and chromatin bivalency. Overall design: RNA-seq for LNCaP, C42B, LNCaP_42D, LuCaP_35CR, MyC-CaP with different treatment.