Multi-Tissue Transcriptomic Profiling of Thyroid-Associated Ophthalmopathy (TAO): Conjunctival, Nasal, and Fecal Samples from 25 Patients and 10 Controls
This dataset includes comprehensive transcriptomic data from 25 patients diagnosed with Thyroid-Associated Ophthalmopathy (TAO), with samples collected from various tissue sources: orbital adipose tissues, conjunctival sac swabs, deep nasal swabs, and feces. In addition, 10 control samples were collected using sterile water for comparative analysis. The aim of this project is to explore the molecular and cellular differences between TAO patients and healthy controls at a multi-sample level. The data provide insights into the gene expression profiles across different tissue types, potentially revealing key markers and pathways involved in the pathogenesis of TAO. This multi-dimensional dataset serves as a valuable resource for understanding the systemic nature of TAO and the role of immune response in the disease's development. The samples were collected rigorously to ensure high-quality data, and the project is designed to aid in further studies of TAO and similar autoimmune conditions. The results may provide valuable biomarkers for diagnosis and therapeutic targets, contributing to better understanding and management of TAO.