The effect of Leech on High-glucose induced HBZY-1 cells.
In this study, the effect and underlying mechanism of Leech extract on high-glucose indueced mesangile cells proliferation and ECM accumulation were investigated based on transcriptomic analysis and experiments in vitro. (RNA-seq was used to analyze the differential genes among three groups, the control group, the high-glucose induced group and the Leech treatment goup,respectively. And all samples were assayed three times.)