Whole genome sequencing of SARS-CoV-2 using amplicon-based sequencing, random hexamers, and bait capture
The primary objective of this analysis is to compare genome sequencing results from direct amplification of the SARS-CoV-2 genome (i.e. the Liverpool or ARTIC PCR protocols) with bait capture enrichment, from COVID-19 patient swabs with markedly different viral titres.