Study of Bifidobacterium in infants born during three time periods (1997-2001, 2005-2009, 2015-2022)
We studied 50 deliveries grouped by the year of birth into three time periods (1997-2001, 2005-2009, 2015-2022). Full-term breastfed infants fecal samples at the age of 1-3 months were collected for microbiota profiling by 16S rRNA gene sequencing. Perinatal factors including mode of birth, antibiotic exposure during pregnancy and at birth were taken into account.