Mus musculus Transcriptome or Gene expression
The 10-week-old male C57BL/6JNifdc mice were randomly divided into two groups: Normal Control (NC) group (n=4) and CKD group (n=4). We utilized an established adenine diet model to induce CKD in mice. NC mice or CKD mice respectively received AIN-93G diet or 0.2% adenine AIN-93G diet (Dyets, Bethlehem Pennsylvania, USA) for six weeks. At week 6, kidney was collected for RNA sequencing.