Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice
The dataset describes the host transcriptional response in WT and Collaborative Cross lines infected with Norway rat hepacivirus. Overall design: We infected WT C57BL/6 mice as well as Collaborative Cross strains CC046, CC071 and CC080 with 1E+05 genome equivelents of Norway rat hepacivirus. Bulk RNAseq was performed on total RNA from the liver at 7 days post infection.