The hypouricemic and renal protective effects of the Chinese functional tea Ligustrum robustum on hyperuricemic mice
HUA is a prevalent metabolic disorder requiring safe, effective interventions. Ligustrum robustum, a Chinese functional tea approved as a general food by the National Health Commission of the People's Republic of China, was studied for its anti-HUA and renoprotective effects in potassium oxonate and hypoxanthine induced HUA mice. Transcriptomics combined with RT-qPCR and HE staining revealed that LR ameliorated renal inflammation by suppressing the TNF/NF-kB pathway.