PRMT3-mediated cellular and molecular regulation in brain tumour stem cells.
Effect on gene expression profilng of BTSCs following PRMT3 inhibition with SGC707. To investigate the role of PRMT3 in regulating the cellular and molecular features of BTSCs, we performed RNA-seq using samples obtained from SGC707 treated versus XY1 treated GBM BTSCs. Overall design: Comparative gene expression profiling of RNA-seq data obtained from SGC707 treated versus XY1, negative probe, treated BT248 cells (3 biological replicated).