Effect of HSD52 overexpression on gene expression in LN229 glioma cells
In order to study the effect of HSD52 on the malignant progression and chemotherapy resistance of glioma, we examined the effect of HSD52 on the gene expression of brain glioma cells. We used lentiviral constructs to establish the LN229 cell line overexpressing HSD52. We subsequently performed gene expression profiling using RNA-seq data obtained from control LN229 cells and HSD52-overexpressing LN229 cells. Overall design: Comparative gene expression profling analysis of RNA-seq data for control LN229 cells and LN229 cells with HSD52 overexpression