Necroptosis enhances 'Don't eat me' signal and induces macrophage extracellular traps to promote pancreatic cancer liver metastasis [THP1-derived macrophages]
We delved into the consequences of macrophages that co-cultured with PDAC cells with Vector/MLKL overexpression. We treated THP1 derived macrophages with PANC1 cells with Vector/MLKL overexpression. Overall design: THP1-derived macrophages cells co-cultured with Panc1-oe-Vector and THP1-derived macrophages cells co-cultured with Panc1-oe-Vector