Generation of intestinal organoids from human urine cells
Intestinal organoids are ideal models for studying human intestinal diseases. We report functional intestinal organoid models (U-iIOs) generated by reprogramming human urinary epithelial cells (hUCs). RNA-seq reveals the intestinal lineage identity of U-iIOs. Overall design: Human urine cells are induced as intestinal organs. We analyzed the transcriptome expression profiles (RNA-seq).