Metagenomic analysis of ulcerative colitis mouse
Ulcerative colitis (UC) remains a challenging chronic inflammatory bowel disease worldwide, largely due to the heterogeneity in patient treatment responses. Emerging evidence highlights the involvement of gut microbiota and circulating metabolites in UC pathogenesis, yet the precise causal relationships remain to be defined. Notably, Veillonella parvula has recently been implicated in disease exacerbation, but the mechanisms underlying its pathogenic role are still unclear.