Single-Cell Transcriptomic Profiling of the MEPP Murine Ovarian Cancer Model (PRJCA037632)
This dataset comprises single-cell RNA sequencing (scRNA-seq) data from the MEPP (Murine Ovarian Epithelium with Pten and Trp53 Deletions) model, an in vivo system that recapitulates the genetic landscape of PTEN-deficient ovarian cancer. MEPP was developed to investigate the molecular mechanisms driving tumorigenesis and metastasis in ovarian cancer. The dataset includes transcriptomic profiles of epithelial tumor cells, stromal components, and immune cell populations, enabling a detailed characterization of cellular heterogeneity and tumor microenvironment interactions.