A Transcriptome Sequencing Dataset from the Longissimus dorsi Muscle of CD163/pAPN Double-knockout Pigs (PRJCA050287)
This dataset comprises comprehensive whole-transcriptome deep sequencing data from the Longissimus dorsi muscle of CD163/pAPN double-knockout (DKO) pigs and their wild-type (WT) counterparts, including biological replicates. It provides high-depth expression profiles for four major RNA classes: messenger RNAs (mRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs). This resource serves to systematically identify transcriptomic alterations induced by gene editing, supports the safety assessment of multi-virus resistant gene-edited pigs, and establishes a foundational molecular atlas for investigating gene editing functionality and the safety of genetically engineered livestock.