Diabetic Maxillofacial mesenchymal stem cells (PRJCA050007)
To investigate the mechanism behind elevated 4-GBA levels in hyperglycemic conditions, we performed single-cell RNA sequencing (scRNA-seq) on tissues surrounding the extraction socket 24 hours after model establishment. Cell clustering based on three specific marker genes for each subtype identified nine major cell clusters: erythrocytes, monocytes, endothelial cells, T cells, B cells, basal cells, neutrophils, Alp+ JBMSCs, and ciliated cells.