nonCG DNA methylation and small RNAs shaping soybean environmental adaptation (PRJCA036454)
In this study, we report single-base resolution DNA methylomes, transcriptomes, and sRNAome of soybean accessions from different geographical distributions and with distinct phenotypic differences (HH43, HX3 and Wm82). The comprehensive DNA methylation landscape and identified DNA methylation variations associated with soybean domestication and adaptive divergence were profiled. By an integrated analysis of multi-omics, we revealed the effect of DNA methylation variations on influencing gene expression, providing valuable epigenomic resources for vegetable improvement through epigenetic engineering, highlighting the intricate interactions between gene expression, DNA methylation, sRNAs, and environmental factors.