C9orf50: A Novel Regulator of RNA Splicing and Therapeutic Target for Colorectal Cancer Immunotherapy (PRJCA029612)
In this study, we utilized CRISPR knockout screening in immunocompetent C57BL/6 mice, combined with functional analyses, to identify C9orf50 as a previously uncharacterized regulator of innate immunity and a potential therapeutic target in colorectal cancer.