mRNA-sequencing analysis of acetabular cartilage samples from dysplasia of the hip rats (PRJCA050984)
In the present study, we successfully established a swaddling-induced rat model of developmental dysplasia of the hip (DDH) that recapitulated key pathological features, including acetabular labral tears and cartilage degeneration. To identify critical regulators underlying DDH pathogenesis, we performed gene expression profiling analysis via mRNA sequencing (mRNA-seq) on acetabular cartilage samples from DDH rats and control counterparts.