Effects of Coprococcus catus on Blood Pressure Regulation and Vascular Remodeling in Hypertensive Mice (PRJCA050752)
This study investigates the antihypertensive effects and mechanisms of Coprococcus catus supplementation in angiotensin II induced hypertensive mice. The project integrates metagenomic, metabolomic, and transcriptomic analyses to explore how Coprococcus catus modulates host taurine metabolism, vascular remodeling, and blood pressure regulation. The findings are expected to provide mechanistic insights into microbiota based interventions for hypertension.