RNA-seq data of CGRP restrains CD4+ T cell responses and allergic sensitization (PRJCA046604)
This project explores the role of the CGRP-RAMP1 pathway in adaptive immunity. We show that CGRP restrains CD4+ T cell activation and Tfh differentiation through transcriptional reprogramming, and that exogenous CGRP treatment mitigates allergic sensitization and asthma in vivo.