Transcriptome data of BalB/c mice infected with Leishmania dueringii treated with anti-PD1 antibody (PRJCA051380)
Three hub genes associated with immune restoration were identified. The study demonstrated PD-1 inhibition reinvigorated anti-parasitic immunity through multimodal mechanisms and illuminated both the potential and intricate dynamics of immune checkpoint modulation in Leishmaniasis, where treatment success hinges on orchestrating spatially coordinated immune activation.