The blockade of circulating FAM3D, a newly identified neutrophil checkpoint, strengthen neutrophil function against bacterial infection (PRJCA021245)
To investigate the involvement of FAM3D in neutrophil heterogeneity during infection, single-cell RNA sequencing (scRNA-seq) was performed on peripheral blood (PB) and peritoneal lavage fluid (PL) samples collected from both WT and Fam3d-/- mice following E. coli-induced peritonitis.