RanGAP1 maintains chromosome stability in limb bud mesenchymal stem cells during bone development (PRJCA021072)
To  determine the readout of aneuploidy in Rangap1-depleted limb bud MSCs, Whole-genome sequencing (WGS, 40X)  was applied to detect different types of structural variations, such as ITX, INV, DEL and INS.