Male germ cell-specific deletion of eukaryotic translation initiation factor 5 causes the apoptosis of mouse progenitor spermatogonia by excessive endoplasmic reticulum stress and defective DNA repair (PRJCA036751)
To determine whether eIF5 plays a crucial role in spermatogenesis, we generated germ cell conditional Eif5 knockout mice by crossing Eif5fl/fl mice with Stra8-Cre mice.