db/db mice (BKS background)- Obesity, Type 2 diabetes, fatty liver research model (PRJCA021242)
db/db mice (BKS background)- Obesity, type 2 diabetes, fatty liver research model, db/db(C57BL/KsJ) mice are Leptin receptor point mutations lead to leptin signaling pathway disorders, resulting in obesity, insulin resistance, hyperglycemia, fatty liver and other symptoms of mice. db/db mice showed obvious obesity and increased fasting blood glucose, water intake and urine volume at 6 weeks after birth, the most obvious at 8-12 weeks, and diabetes and nephropathy and other complications.