Multiomics Analysis Reveals How Intratumoral Bacteria Shape the Immune Microenvironment in Gastric Cancer (PRJCA042633)
The occurrence and progression of gastric cancer (GC) are highly influenced by dysbiosis of the gastric microbiota and host immune system. As critical factors in gastric carcinogenesis, the relationship between intratumoral bacteria and gastric microenvironments remains un-elucidated. This study characterized the biological profile of the intratumoral bacteria, metabolome, and proteome from 20 GC tumors and paired non-tumor tissues.