The effect of inhibiting fibronectin on TNBS induced intestinal fibrosis (PRJCA044071)
This project investigates whether fibronectin inhibition alleviates intestinal fibrosis and assesses its transcriptional impact, employing TNBS-induced chronic enteritis mouse models: the T group (full-course induction), TA group (ATN161 treatment), and TP group (pUR4 treatment), wherein ATN161 and pUR4 are domain-specific fibronectin inhibitors.