Lactobacillus delbrueckii Strain Capable of Effectively Adsorbing Microplastics and Evaluation of Its Efficacy in Alleviating Microplastic-Induced Enteritis
This study aims to screen and explore probiotic strains with the potential to alleviate intestinal damage caused by polystyrene microplastics (PS-MPs). The study first conducted preliminary screening based on the intestinal adhesion capacity of probiotics and their adsorption rate toward PS-MPs. Subsequently, using HT-29 and Caco-2 cell models, the in vitro assessment evaluated the mitigating effects of candidate strains on PS-MPs-induced cytotoxicity. Finally, through animal experiments, the in vivo validation confirmed the improvement of intestinal damage caused by PS-MPs by the candidate probiotics. Results indicate that Lactobacillus delbrueckii significantly promotes the in vivo excretion of PS-MPs, reducing their accumulation in intestinal tissues and effectively mitigating PS-MP exposure-induced intestinal damage. This study provides experimental evidence for developing probiotic-based dietary intervention strategies, demonstrating potential application value in reducing health risks associated with environmental microplastic exposure.