study on the role and mechanism of SOCS6 in keratinocytes
Atopic dermatitis is a severe skin disorder. Keratinocytes, as the epidermal barrier cells, are an important component in maintaining the skin barrier function. The role of SOCS6 in keratinocytes is still unclear. In this dataset, we extracted keratinocytes from the foreskin tissue of healthy individuals and conducted mRNA sequencing data for SOCS6 knockdown (KD) and overexpression (OE). Overall design: Knockdown and overexpression of SOCS6 were respectively compared with the control group to explore the effect of SOCS6 on keratinocytes.