This project investigates the anti neuroinflammatory mechanism of scopoletin in microglial cells.
This project aims to investigate the transcriptomic changes induced by scopoletin in BV2 microglial cells following lipopolysaccharide stimulation. BV2 cells were divided into three groups: control, LPS treated, and LPS + SP treated. RNA sequencing was performed to explore the global gene expression alterations associated with the anti-inflammatory and neuroprotective effects of scopoletin. Comparative analysis identified differentially expressed genes involved in immune and inflammatory signaling pathways, providing insights into the molecular mechanisms through which SP modulates microglial activation and neuroinflammation.