GSE184003
RNAseq analysis of osteosarcoma cell line with overexpression of YAP-S94A and YAP-S127A
The molecular mechanisms by which YAP regulates metastases development were studied using overexpression of mutated forms of YAP able or not to interact with TEAD. Molecular signatures were identified using RNA-sequencing analysis and genes set enrichment. Overall design: Osteosarcoma cell line KHOS overexpressing two different form of YAP protein : YAP-S94A and YAP-S127A