GSE158234
Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer's pathology in vivo [scRNA-seq]
scRNA-sequencing of human xenotransplanted microglia isogenic for TREM2 after exposure to amyloid pathology Overall design: Single-cell comparison of WT and KO TREM2 microglia isolated from 6 month old WT and 5X-MITRG mice