DRP008114
ChIP-seq analysis of H3K27me3 in HSPCs from Ct and UTX cKO mice
To investigate the role of UTX in hematopoiesis, we generated UTX conditional knockout (cKO) mice. These cKO mice were crossed with Cre-ERT2 mice to defect   UTX expression in a hematopoietic cell-specific manner. To detect the alterlation of H3K27me3 levels,  we performed ChIP-seq analysis using HSPCs from Ct and UTX cKO mice.