GSE159524
A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae
This study investigates the suitability of neochromosomes as orthogonal expression platforms for rewiring native cellular processes and implementing new functionalities. Overall design: Comparison of gene expression between a strain with exclusive expression of glycolysis from a neochromosome (IMF17) and a strain with expression of glycolysis from the native genome (IMX2109).