PRJNA824682
knockdown RAC3 in bladder cancer cell lines
RAC is a member of the Rho GTPase subfamily, including three isoforms of RAC1, RAC2, and RAC3, and their homology exceeds 90%. There is substantial evidence that RAC proteins are involved in various cellular processes. Among them, RAC3 is overexpressed and is involved in the initiation and progression of different types of cancers. However, how RAC3 contributes to bladder cancer progression and its mechanism is still lacking.