PRJNA863855
Transcriptomic data of Saccharomyces cerevisiae YPH 499 carrying a nonribosomal peptide synthetase gene from Paecilomyces cinnamomeus BCC 9616
Heterologous expression of nrps33, a nonribosomal peptide synthetase gene, from Paecilomyces cinnamomeus BCC 9616 in Saccharomyces cerevisiae YPH 499 unexpectedly resulted in the accumulation anthranilic acid, an intermediate in the tryptophan biosynthesis. Based on transcriptomic and RT-qPCR results, the expression of nrps33 affected the transcriptomic level of some genes in the tryptophan biosynthesis especially trp1 which is also the selectable auxotrophic marker for expression vector used in this work.