GSE184765
Effects of TNF on 'starved' primary hepatocytes
We generated transcriptional profiles of TNF-stimulated primary hepatocytes co-treated with PPARa and GR ligands to mimic a condition of starvation. Overall design: Primary hepatocytes were cotreated with corticosterone (GR ligand), WY-14643 (PPARa ligand), and TNF for 8 hours to assess the effect of TNF on 'starved' hepatocytes.