GSE183361
RNA-seq analysis of zip-1(jy13) mutants (ERT590) following 0.5 h and 4 h BTZ treatment
Comparison of gene expression in wild-type and zip-1(jy13) mutant animals following bortezomib or DMSO (control) treatment. We report that induction of some genes upon bortezomib treatment is zip-1 dependent. Overall design: Synchronized populations of N2 and zip-1(jy13) animals that were grown at 20°C for 48 h were treated with DMSO or bortezomib (BTZ) for 0.5 h or 4 h. Total RNA was isolated. 3 experimental replicates were performed.