ena-STUDY-UNIVERSITY OF OXFORD-22-09-2020-15:44:28:208-85
The bacteriology of pleural infection using next generation sequencing: The Oxford Pleural Infection Metagenomics Studies (TORPIDS)
Pleural infection is a complicated, severe and frequent disease worldwide. The knowledge of pleural infection microbiology remains incomplete. We designed a translational metagenomics study to investigate the bacteriology of pleural infection. Pleural fluid biospecimens from the Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study were subjected to bacterial DNA extraction and 16S rRNA next generation sequencing. Pleural fluid samples from patient without pleural infection were used as negative control.
Pleural infection is a complicated, severe and frequent disease worldwide. The knowledge of pleural infection microbiology remains incomplete. We designed a translational metagenomics study to investigate the bacteriology of pleural infection. Pleural fluid biospecimens from the Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study were subjected to bacterial DNA extraction and 16S rRNA next generation sequencing. Pleural fluid samples from patient without pleural infection were used as negative control.