PRJNA576707
RNA-seq of evolved S. cerevisiae strains with improved tolerance to lignocellulosic derived inhibitors
Pretreated pinewood as a dedicated feedstock for bioethanol production is a promising but challenging substrate for fermentation. An industrial S. cerevisiae strain was subjected to directed evolution and adaptation and resultant strains exhibited improved growth and fermentative ability on pretreated pine in the presence of related inhibitory compounds. A comparative transcriptomic approach was applied to identify and characterize differences in phenotypic stability of evolved strains.