GSE203058
Estrogen receptor a-mediated signaling  inhibits type I interferon response to promote breast cancer
To investigate the molecular mechanisms by which estrogen receptor a (ERa) inhibits type I IFN-induced signaling. We identified genes induced by ERa signaling using data obtained from RNA-seq of MCF7 cells treated or untreated with selective ERa agonist propyl pyrazole triol (PPT). Overall design: Differential gene expression analysis of RNA-seq data for MCF7 cells treated or untreated with PPT (5 nM) for 16 hours.