GSE129754
PRMT1-mediated FLT3 arginine methylation promotes FLT3-ITD+ Acute Myeloid Leukemia maintenance
We want to obtain FLT3-ITD gene signature. To do so, we transduced  CB CD34+ cells  with mock or FLT3-ITD vectors and performed RNA sequencing (RNA-Seq). Two Groups: Group1: CB CD34+ cells transduced with mock vector; Group2: CB CD34+ cells transduced with FLT3-ITD vector; Overall design: Expression profiling data in FLT3-ITD+ Cord blood cells were compared to corresponding control mock transduced cells by RNA-seq technology