GSE194236
Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus
Transcriptomic profile of rat choroid plexus (whole tissue) of both male and female sex, epithelial cells captured by fluorescence-activated cell sorting (FACS), and compared to proximal tubules of the kidneys. The transcriptomic profile of choroid plexus displays high similarity between sex and choroid plexus epithelial cells, and lesser similarity to another secretory epithelium, the proximal tubules. The analysis provides an insight into transport mechanisms that could participate in CSF secretion and suggest regulatory candidates. Overall design: mRNA profile analysis of whole tissue choroid plexus for both male and female, choroid plexus epithelial cells, and kidney proximal tubules in rats.