ena-STUDY-WTSI-23-08-2018-14:47:00:469-26
Novel Ornithobacterium species from human nasopharyngeal samples
Candidatus Ornithobacterium hominis sp. nov. represents a new member of the Flavobacteriaceae previously detected in 16S rRNA gene surveys from Southeast Asia, Africa and Australia. It colonises the infant nasopharynx at high proportional abundance, and is highly prevalent in children in Maela camp, Thailand. The species, a Gram negative bacillus, has not yet been cultured but the cells can be identified in mixed samples by fluorescent hybridisation. The genomes share 62% average amino acid identity with the only other member of the genus, the bird pathogen Ornithobacterium rhinotracheale. Intra- and inter-host genome comparison suggests that colonisation with this bacterium is both persistent and strain exclusive.
Candidatus Ornithobacterium hominis sp. nov. represents a new member of the Flavobacteriaceae previously detected in 16S rRNA gene surveys from Southeast Asia, Africa and Australia. It colonises the infant nasopharynx at high proportional abundance, and is highly prevalent in children in Maela camp, Thailand. The species, a Gram negative bacillus, has not yet been cultured but the cells can be identified in mixed samples by fluorescent hybridisation. The genomes share 62% average amino acid identity with the only other member of the genus, the bird pathogen Ornithobacterium rhinotracheale. Intra- and inter-host genome comparison suggests that colonisation with this bacterium is both persistent and strain exclusive.