GSE172193
Knockout of circRNAs by base editing back-splice sites of circularized exons
Subcellular RNA-seq datasets are used for genome-wide analysis of circRNAs in 293FT cells. Here we knocked out circRNAs by base editor (BE)-mediated nucleotide changes. Overall design: Poly(A)+, poly(A)- and RNaseR-treated RNAs of 293FT cells are extracted and sequenced for downstream circRNA analysis.