E-MTAB-10041
RNA-seq of mouse colon to investigate how suppression of HSF1 activity by wildtype p53 creates a driving force  for p53 loss-of-heterozygosity
Mice with colonic tumors (chemically induced by AOM/DSS) were treated with Nutlin or control vehicle solution to analyze p53 target gene expression in vivo.
Mice with colonic tumors (chemically induced by AOM/DSS) were treated with Nutlin or control vehicle solution to analyze p53 target gene expression in vivo.