PRJNA576701
Transcriptome profile of  conceptuses (embryos and fetuses)  from  dietary L-arginine supplemented pregnant gilts
Prenatal losses can vary between 25 and 50%, which represents a high percentage of mortality in pigs. With the reduction of mortality from 1 to 2% there is a greater economic return from the activity, by the direct increase in the number of weaned piglets/female/ year. Once we understand the regulatory determinants of early embryonic development, as well as dietary levels and selection criteria, we may be able to improve reproductive efficiency in pigs. Nutrition during pregnancy influences the development of the female, the size, weight, and uniformity of the litter, as well as productivity during lactation and the weaning interval. Dietary levels of some amino acids and vitamins can dramatically affect the regulation of gene expression and reduce the incidence of diseases or defects of the embryo during development. Based on these premises, the proponents aim to characterize the transcriptome in embryos (25 days-old) and fetuses (35 days-old) of commercial lineage generated from females supplemented and not supplemented with L-arginine, as well as to note, compare and quantify the differential expression of genes related to the conceptuses development at 25 and 35 days of gestation from control gilts.