Transcriptomics_study_of_mouse_and_human_macrophage_and_intestinal_organoids_in_response_to_pathogen-sc-3202
Transcriptomics_study_of_mouse_and_human_macrophage_and_intestinal_organoids_in_response_to_pathogen
Aim of this study is to understand the transcriptional response of macrophages and intestinal epithelial cells to pathogen challenge. These data are part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
We are generating macrophage and intestinal organoids from primary mouse and human tissues or induced pluripotent stem cells (iPSCs), these macrophages and organoids are challenged with live or dead pathogens/pathogen components in combination with various immune regulatory cytokines and growth factors.