GSE96965
Identification and mode of action of a plant natural product targeting human fungal pathogens
Candida albicans was subjected to treatment with tomatidine and samples were taken at 2 different time points (1h, 3h). The results show that tomatidine induces genes involved in ergosterol biosynthesis as compared to untreated controls. Overall design: C. albicans SC5314 strain was exposed to 250 µM tomatidine and total RNA was extracted after 1 h or 3 h tomatidine/solvent exposure.