GSE125381
Next Generation Sequencing Facilitates Quantitative Analysis of MYC+ and MYC+; SETD2-/- Renal Tubular Cells Transcriptomes
To get an insight into the mechanism of how SETD2 ablation promotes ccRCC, we performed RNA-seq using the renal tubules isolated from MYC+; SETD2-/- mice compared with their control MYC+ littermates. Overall design: Renal primary tubular epithelial cells mRNA profiles of 6- to 8-week-old SETD2FL/FL KSPCRE/+ and MYC+; SETD2FL/FL KSPCRE/+ mice were generated by deep sequencing, in triplicate, using   Illumina NextSeq 500.