PRJNA478211
mouse cecal microbiota Targeted loci (16S)
A previous study by the group of investigators found wild-type (WT) and macrophage-specific JNK1/2 knock-out (KO) mice developed similar degrees of obesity when fed a high-fat diet, however the KO mice remained insulin sensitive. This follow-up study was conducted to characterize the cecal microbiota changes that occur in WT versus KO mice. Sequencing data was generated cecal contents of high fat -fed, ampicillin-treated control (Lyz Cre+) and macrophage-JNK KO (Lyz Cre+JNK1f/fJNK2f/f) mice.