GSE108680
MARCKS and lnc-MARCKS act as inflammation regulators
The goals of this study are to reveal the target transcriptome of MARCKS and lnc-MARCKS in TLR2 signaling pathway. We knocked down MARCKS, or over-expressed lnc-MARCKS in THP1-derived macrophages stimulated with Pam3CSK4 for 8 hours. And compared the transcriptomes of the editing cells with control cells Overall design: Transcriptome in MARCKS knock-down or lnc-MARCKS overexpressed cells