GSE202245
WGBS of primary and recurrent ovarian cancer tumors with and without BRCA1/2 mutations
WGBS was generated for a cohort of ovarian cancer patients to identify DNA methylation changes between primary and recurrent ovarian cancer tumors from patients with and without BRCA1/2 mutations Overall design: We performed whole genome bisulfite sequencing in 62 primary and  recurrent  tumors  from  28  patients  with  stage  III/IV  high  grade  serous  ovarian  cancer (HGSOC), of which 11 patients carried germline, pathogenic BRCA1and/or BRCA2mutations