ena-STUDY-SAN RAFFAELE RESEARCH INSTITUTE-18-12-2018-17:35:16:446-208
Whole genome sequencing-based characterization of MDR and XDR strains of Mycobacterium tuberculosis isolated in Tunisia
Forty-six multidrug-resistant (MDR) strains of Mycobacterium tuberculosis isolated between 2012 and 2016 in Tunisia underwent whole genome sequencing. Thirty isolates (65.2%) were grouped within 3 clusters by core genome multilocus sequence typing analysis indicating an extensive recent transmission of MDR strains with a predominance of a Haarlem clone.
Forty-six multidrug-resistant (MDR) strains of Mycobacterium tuberculosis isolated between 2012 and 2016 in Tunisia underwent whole genome sequencing. Thirty isolates (65.2%) were grouped within 3 clusters by core genome multilocus sequence typing analysis indicating an extensive recent transmission of MDR strains with a predominance of a Haarlem clone.