GSE195588
Bulk RNA-sequencing analysis of E17.5 DA from Prdm6f/f; SM22-Cre mice and wildtype littermates
RNA-sequencing analysis of E17.5 DA from Prdm6f/f; SM22-Cre mice and wildtype littermates identified contractile proteins such as Tagln and Myh11 as the most downregulated genes in the DA of Prdm6f/f; SM22-Cre mice vs. wildtype littermates from 280 differentially exressed genes. Strikingly, the expression levels of the Tfap2b and Sox9, which also function as NCC specifiers were significantly reduced at in DA of Prdm6f/f; SM22-Cre vs. wildtype littermates Overall design: RNA-sequencing analysis of E17.5 DA from WT and Prdm6f/f; SM22-Cre mice.