GSE195717
Transcriptomic profiling of kidney organoids treated with QNZ
We performed RNA-Seq on wildtype or PDK2-null human kidney organoids treated with various concentration of QNZ or control. For WT organoid we started QNZ treatment on day8 and harvested the samples on day28. For PKD2 null organoids we started treatment on day13 and harvested the samples on day20 We performed RNA-Seq on PDK2-null human organoid derived cysts treated with various concentration of QNZ or control. We started QNZ treatment on day3 and harvest on day9. Overall design: cyst and organoid mRNA profiles of QNZ treatment vs. DMSO treatment