ena-PROJECT-RPI-03-12-2012-05:36:38:676-84
Draft Genome Sequence of Escherichia coli Strain ATCC #23506 (serovar O10:K5(L):H4)
We report the 5.101-Mbp high-quality draft assembly of the Escherichia coli strain ATCC #23506 (serovar O10:K5(L):H4, also known as NCDC Bi 8337-41) genome. This uropathogenic strain produces N-acetyl heparosan, a glycosaminoglycan-like capsular polysaccharide and precursor to the anticoagulant pharmaceutical heparin. Metabolic reconstruction of this genome will enable prediction of gene deletions and overexpressions leading to increased heparosan production.
We report the 5.101-Mbp high-quality draft assembly of the Escherichia coli strain ATCC #23506 (serovar O10:K5(L):H4, also known as NCDC Bi 8337-41) genome. This uropathogenic strain produces N-acetyl heparosan, a glycosaminoglycan-like capsular polysaccharide and precursor to the anticoagulant pharmaceutical heparin. Metabolic reconstruction of this genome will enable prediction of gene deletions and overexpressions leading to increased heparosan production.