GSE51181
VDR ChIP-seq in PMA-differentiated macrophages (human M2-type like macrophages)
We performed ChIP-seq in macrophage-type PMA-differentiated THP-1 cells after stimulation with the the natural VDR ligand 1,25dihydroxyvitamin D3 (1,25D). We identified in total 223 VDR binding locations on chromatin after 1,25D treatment. De novo analysis of VDR site sequences identified DR3-type binding sites as major motif. Overall design: PMA-differentiated THP-1 cells were treated for 0, 1 and 2 h  with 100 nM 1,25D