GSE129187
Reduced Representation Bisulphite Sequencing of WT and AICDA KO iPCS clones
We report AICDA facilitates naïve pluripotency of mouse iPSCs by suppressing FGF/ERK signaling. In the absence of AICDA iPSCs fail to achive naïve pluripotent state and display chracteristics of EpiSCs and are primed for differentiation. Overall design: IPSC clones from WT and AICDA KO fibroblasts were reprogrammed using OSKM.