GSE158475
Transcriptome profiling of Mature B cells residing in the bone marrow.
Purpose: The role of intrinsic apoptosis in mature B cell homeostasis is still elusive. The aim of this study is to compare the transcriptome of mature B cells that are either sensitive or resistant to intrinsic apoptosis. Methods: Bone marrow-residing Mature B cells were FACS-sorted as B220high CD93- IgM+ with >99.8% purity.  RNA was extracted with Qiagen RNA extraction kit. Overall design: 12 samples in total, n=3 biological replicates per experimental group.