GSE110690
Beta cell dysfunction and identity loss induced by low dose of Interleukin-1ß is associated with changes in histone acetylation and gene expression [RNA-seq]
We report maturity loss and dysfunction of primary mouse islets exposed to prolonged low Interleukin-1B exposure is associated with a decreassed expresion of key beta cell genes and a decreased H3K27ac mark Overall design: Examination of mRNA profile of primary mouse islets exposed or non-exposed to Interleukin-1B for 10 days