GSE136267
Analysis of Drosophila melanogaster Chromosome Topology in Larval Eye and Antennal Discs
The goal of this study was to examine chromosome topology in Drosophila larval eye and antennal discs by identifying topologically associating domains (TADs) across the genome. TADs were compared between the eye and antennal disc to determine whether they contribute to cell-type-specific homologous pairing and transvection. Overall design: HiC profiles of Drosophila third-instar larval eye and antennal discs were generated by deep sequencing in triplicate.