GSE116759
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome
Naked mole-rat skin fibroblasts (NSF) produces vHMM-HA. Although NSF-HA has been shown to suppress NSF transformation, it is still unclear if exceptional polymer length of vHMM-HA is important for its functions. Here, we compared the effect of intact control NSF-HA (cNSF-HA) and partially fragmented NSF-HA (fNSF-HA) on the transcriptome of IMR90 cells. Related RNA-Seq datasets are deposited in ArrayExpress (E-MTAB-8943). Overall design: Transcriptome of IMR90 cells treated with PBS, cNSF, fNSF were analyzed before and after exposing cells to oxidative stress.