GSE115184
The methyltransferase HEN1 is required for microRNA and piRNA stability as well as larval metamorphosis in Nematostella vectensis
Knockdown of Dicer and PIWI2 in Nematostella results in a developmental arrest. Small RNA sequencing revealed that the levels of both miRNAs and piRNAs drop dramatically in the morphant animals. Overall design: Employ high throughput sequence of endogenous small RNAs