GSE129222
Insulin-regulated periovulatory gene expression in superovulated mice
Because mice with Pgr-Cre mediated double ablation of Insr and Igf1r are infertile and possess trapped oocytes in their corpora lutea, we performed RNA-seq to identify candidate pathways that contribute to ovulation failure. Overall design: A direct comparison of conditional Insr/Igf1r double knockout mice with littermate controls (n=4 per group).