GSE129563
Couple transcriptome and genomic data obtained from the PDXs to identify pathways linking oncogenic alterations
Purpose: Study  the changes in cell transcriptome in breast cancer with respect to normal breast tissue in association with somatic mutations Methods: RNA was extracted from frozen normal breast tissues and PDXs cells Results: We found over-expression of oncogenic pathways associated with oncogenic mutations in PDXs Overall design: Analysis of differential gene expression in metastatic breast cancer PDXs