PRJNA549145
Sequencing data of 293FT cells edited by Proxy-BE and BE
In our research, the Proxy-BE strategy was confirmed by SpdCas9-assisted SaKKH-BE3 and dCpf1-BE, with twice of base editing efficiency as compared with canonical base editing. This work provides a feasible approach to enhance base editing, which extends the scope of base editing for gene therapy.