GSE169577
The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells
The  accessibility chromatin patterns during hPGCLCs undergo a diverse changes in absence of SOX15. The consequence of these changes lead to a somatic gene network activation that leads to decrease hPGCLC at late stage Overall design: We analyzed the transcription factors binding profiles using cut-tag sequencing in human primordial germ cell like cells (hPGCLCs) comparing to SOX15-/-