Yeast_KO_Seq_Strategy_1__Mutational_signatures_of_DNA_damage_and_repair_processes-sc-3317
Yeast_KO_Seq_Strategy_1__Mutational_signatures_of_DNA_damage_and_repair_processes
Mutational signatures attributable to all viable S.cerevisiae gene knockouts (approx. 4000) will be determined. 8 samples from each knockout will be grown. The 8 samples will then be pooled, with WGS performed to higher coverage on the resulting pooled sample.
This work is part of the broader WTSA investigating mutational signatures of DNA damage and repair processes.  Mutational signatures attributable to all viable S.cerevisiae will be determined.