GSE123463
Total uterus transcriptome after depletion of regulatory T cells at E8 of murine pregnancy
Regulatory T cells (Tregs) contribute to successful pregnancy by promoting maternal-fetal tolerance. We depleted Tregs using diphtheria toxin (DT) in the Foxp3DTR mouse model after allogenic mating with BALB/c males and we performed a complete NGS transcriptome analysis by RNA-seq at 100 million reads/sample of total uterine tissues at day 8 post coitum from control (PBS1X treated) and diphtheria toxin (DT) treated mice. Overall design: Total uterine tissues mRNA profiles of 8 days post coitum pregnant, 8 weeks old, Foxp3DTR females after allogenic mating with BALB/c males. Samples  were generated by deep sequencing using NextSeq Illumina , in quadruplicate, for control (PBS1X treated) and diphtheria toxin (DT) treated mice.