ena-STUDY-Cambridge Department of Veterinary Medicine-22-07-2017-18:29:54:135-491
The origins and vulnerabilities of two transmissible cancers in Tasmanian devils (2018).
Transmissible cancers are clonal lineages that spread through populations via contagious cancer cells. Although rare in nature, two distinct facial tumour clones - DFT1 and DFT2 - affect Tasmanian devils. In this study, we performed a comparative genomic characterisation of these lineages. This set entails high-coverage whole genome sequencing (WGS) data aligned to the Tasmanian devil reference genome 7.1, in BAM format: two DFT1 tumours sampled in 2005 (86T, coverage: 86X) and 2007 (88T, coverage: 67X), two DFT2 tumours sampled in 2014 (202T2, coverage: 67X and 203T3, coverage: 70X), as well as four normal devils sampled in 2006 (91H, coverage: 65X), 2007 (31H, coverage: 17X), and 2014 (202H1, coverage: 49X and 203H, coverage: 45X).  Please cite our paper relating to this data: Stammnitz, M.R. et al. "The origins and vulnerabilities of two transmissible cancers in Tasmanian devils". Cancer Cell 33(4), 607-619 (2018).
Transmissible cancers are clonal lineages that spread through populations via contagious cancer cells. Although rare in nature, two distinct facial tumour clones - DFT1 and DFT2 - affect Tasmanian devils. In this study, we performed a comparative genomic characterisation of these lineages. This set entails high-coverage whole genome sequencing (WGS) data aligned to the Tasmanian devil reference genome 7.1, in BAM format: two DFT1 tumours sampled in 2005 (86T, coverage: 86X) and 2007 (88T, coverage: 67X), two DFT2 tumours sampled in 2014 (202T2, coverage: 67X and 203T3, coverage: 70X), as well as four normal devils sampled in 2006 (91H, coverage: 65X), 2007 (31H, coverage: 17X), and 2014 (202H1, coverage: 49X and 203H, coverage: 45X).  Please cite our paper relating to this data: Stammnitz, M.R. et al. "The origins and vulnerabilities of two transmissible cancers in Tasmanian devils". Cancer Cell 33(4), 607-619 (2018).