GSE159886
Epigenome of ASXL1-mutant and ASXL1-wildtype chronic myelomonocytic leukemia
We report the chromatin characteristics of human chronic myelomonocytic leukemia by performing chromatin immunoprecipitation sequencing of histone modifications (ChIP-seq), immunoprecipitation sequencing of (hydroxy-)methylated residues (DIP-seq), and transposase accessibility sequencing (ATAC-seq) of bone marrow mononuclear cells of patients with chronic myelomonocytic leukemia. Overall design: Comparison of chromatin characteristics between ASXL1-mutant and ASXL1-wildtype chronic myelomonocytic leukemia.