GSE137814
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [Cut&Run]
CRISPR mediated gene inactivation of MEN1 does not lead to loss of MLL1n chromatin occupancy. Overall design: Using MLL1n Cut&Run-seq we examined if CRISPR mediated MEN1 gene inactivation lead to loss of MLL1n chromatin occupancy in MOLM13 cells.