PRJNA542878
identify open chromatin in Arabidopsis using MNase
A method using MNase to identify open chromatin was developed. Chromatin was isolated and treated by MNase. fragments smaller than 100bp were collected and sequenced. These small fragments represent open chromatin regions in the genome. Comparing the DNase-seq, this method can identify more open chromatin regions especially genomic regions enriched with repressive chromatin mark like H3K27me3.