Harvard_Medical_School_BSPP_and_MSCC_Methylation_Data
Harvard Medical School BSPP and MSCC Methylation Data
The bisulfite padlock probe data comes from a set of padlock probes designed to target 10bp regions in bisulfite treated DNA. The probes are polymerized and circularized on this region. Sequencing reads provide sequence for the padlock arms (28bp) followed by reads originating from the target DNA.  Methylation sensitive cut counting data arise from sequences flanking CCGG recognition sites, providing 18-19 unique bases of genomic sequence associated with that site.
Harvard Medical School Bisulfite Padlock Probe (BSPP) and Methylation Sensitive Cut Counting (MSCC) short sequencing reads.