GSE200643
H3K27Ac CUT&Tag-Seq to characterize the epigenetic profiles in colonic macrophages from Tle4KO (Tle4fl/fl, Lyz2-Cre) and WT (Lyz2-Cre) mice
We found that TLE4 maintained epigenetic landscape in colonic macrophages. Overall design: Colonic macrophages were sorted from untreated WT and myeloid cell-specic Tle4 knockout mice. Epigenetic profiles were analyzed by H3K27Ac CUT&Tag-Seq.