GSE202989
PI3K-mediated crosstalk between angiopoietin and vascular endothelial growth factor C signaling pathways is required for lymphangiogenesis
The aim of the study was to invetigate the crosstalk between VEGF-C/VEGFR3 and Ang2/Tie pathway Overall design: ScRNA sequence analysis contains two experiments.In first experiment, lymphatic endothelial cells from Tie1 and Tie1;Tie2 deleted lymphatic endothelial cell. The control for deletion experiments were Tamoxifen treated littermate controls, and the deleted sample had Prox1-CreERT2.