GSE159263
Cancer Stem Cell Phenotypes in ER + Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes
Trascriptome analysis of mcf7 cell lines were performed Overall design: MCF-7 PELP1 cells expressing LXSN, WT PELP1, or cytoplasmic (cyto) PELP1 were hormone-starved in modified IMEM containing 5% DCC for 16 hours prior to hormone treatment. Cells (in triplicate) were treated with vehicle (ethanol) or E2 (10-9 mol/L) for 6 hours, RNA was extracted with RNAeasy Mini Kit and sequenced with Illumina HiSeq 2000