GSE194360
RNA-seq datasets of Ro, GSK-591 and combination treatment in Z-138 cells
Dual targeting of PRMT5 and MSI2 inhibited synergisticly B-cells proliferation. Thus, next-generation sequencing was performed to evaluate the effect of the inhibitors of PRMT5 and MSI2, GSK-591 and Ro, respectively, in the global transcriptome of the mantle cell lymphoma cell line, Z-138. Overall design: Z-138 cells overexpressing MIG (empty vector) were treated for with DMSO, Ro, GSK-591 and combination for 24h and harvested for RNA-seq