GSE160742
S63845 resistance mechnism
MCL-1 plays a central role in B-cell lymphoma progression and drug resistance. Pharmacologically targeting MCL-1, therefore, represents an attractive strategy to combat these lymphomas. S63845, a MCL1 inhibitor, was shown to have high response rates in mantle cell lymphoma (MCL) and burkitt lymphoma. Overall design: RNA sequencing to profile expression in paired parental and S63845 resistant  lymphoma cell lines