GSE120781
Acute depletion of CTCF directly affects MYC regulation through loss of enhancer–promoter looping
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. Gene expression of CTCF in human cancer cells and control uncover the disrupted enhancer-promoter regulation of MYC in human cancer cells. Overall design: RNA-seq library constructed on genome wide deletion of CTCF cells and control.