GSE172472
EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis
We report the gene expression differences in the colonic epithelium of control and Ehf knockout mice assessed by RNA-seq analysis. Overall design: We performed RNA-seq analysis of colonic epithelial cells isolated from 6-week-old Ehf WT and Ehf intestinal knockout (IKO) mice. To account for possible transcriptional changes induced by tamoxifen, Villin CreERT2 mice treated with tamoxifen (Villin CreERT2-TMX) were also analyzed as a further control