PRJNA737397
The ability of AhR ligands to attenuate delayed type hypersensitivity reaction is associated with alterations in the gut microbiota
They performed 16S rRNA sequencing of the gut microbiome on experimental groups to determine the microbial profiles of mBSA-induced Delayed type hypersensitivity mice and those treated with TCDD or FICZ. Experimental groups consisted of PBS+CON, mBSA+Vehicle, mBSA+TCDD and mBSA+FICZ mice. Genomic DNA was isolated from colonic flushes from each group (n=3 per group) and sequencing performed on the V3-V4 16S rRNA regions using Illumina MiSeq platform to determine gut microbial profiles.