GSE209737
miR-145 transgenic mice develop cardiopulmonary complications leading to postnatal death
Both downregulation and elevation of microRNA miR-145 has been linked to an array of cardiopulmonary phenotypes, and a host of studies suggest that it is an important contributor in governing the differentiation of cardiac and vascular smooth muscle cell types. Overall design: Compared wild-type lungs with miR-145 transgenic lungs