GSE138906
H3K79me2 naïve and in vitro activated B cells
We studied the role of the histone methyltransferase DOT1L in B cell development and differentiation. H3K79me2 ChIP-sequencing data was generated from sorted B cells. This was compared to RNA-sequencing data from WT and Dot1L KO mice in order to study the link between H3K79me2 and transcription. Overall design: Examination of H3K79me2 in naïve and activated B cells