E-MTAB-3051
An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins
The methylation profile for 54 MZ twins are generated by methylated DNA immunoprecipitation followed by sequencing on Illumina GAII. Methylation score (RPM and AMS) is quantified using MEDIPS and differentially methylation region in T2D is detected a linear mixed effect model and MZ discordant twin model.
The methylation profile for 54 MZ twins are generated by methylated DNA immunoprecipitation followed by sequencing on Illumina GAII. Methylation score (RPM and AMS) is quantified using MEDIPS and differentially methylation region in T2D is detected a linear mixed effect model and MZ discordant twin model.