GSE135083
transcriptome expression profiling of cisplatin chemoresistance 5-8F cells
Radiotherapy and adjuvant cisplatin (DDP) chemotherapy are standard administrations applied in the treatment of NPC. However, molecular change and functions of DDP chemo-resistance in nasopharyngeal carcinoma are still poorly understood. Overall design: Three independent cell-culture replicates from the total population of 5-8F and stable cisplatin chemoresistance 5-8F (5-8F/DDP) cell lines were used to generate total RNA. Total RNA was extracted using Trizol.