GSE175736
Next Generation Sequencing Facilitates Quantitative Analysis of PVT1 overexpressed MDA-MB-231 cells.
PVT1 can regulates glycolysis related genes expression. Overall design: We over-expressed the PVT1 in MDA-MB-231 cells using the lentiviral construct pLVX-PVT1-EF1a-IRES-EGFP-PGK-puro. We then used RNA sequencing  to compare PVT1 over-expression cells to negative controls(empty vector).