GSE122131
Genome transfer for the prevention of female infertility caused by maternal gene mutation
Maternal gene plays crucial role in the regulation of oocyte maturation and preimplantation embryonic development and its mutation is an important cause of woman infertility Overall design: WT MII oocyte, WT zygotes, Zar1-/- MII oocyte, Zar1-/- zygotes,WT 2 cell embryo,spindle transfer 2 cell embryo, polar body transfer 2 cell embryo and  pronuclear transfer 2 cell embryo are performed RNA sequencing.