GSE99341
Transcriptome data involved in Japanese flounder (Paralichthys olivaceus) albinism
In this study, a high-throughput sequencing strategy was employed to identify the mRNA involved in P. olivaceus albinism. Based on P. olivaceus genome, RNA-seq identified 21,787 know genes and 711 new genes by transcripts assembly. Of those, 235 genes exhibited significantly different expression pattern (fold change =2 or =0.5 and q-value=0.05), including 194 down-regulated genes and 41 up-regulated genes in albino versus normally pigmented individuals. These genes were enriched to 81 GO terms and 9 KEGG pathways (p=0.05). Among those, the pigmentation related pathways-Melanogenesis and tyrosine metabolism were contained. Overall design: Examination of the ocular side skin of wild type and albinism Paralichtys olivaceus