GSE212085
Targeting polyamines catabolism to counteract the detrimental effects of cellular senescence
To investigate the effect of pharmacological targeting of polyamines catabolic enzymes in the establishment and reversion of the senescent phenotype Overall design: Comparative gene expression profiling analysis of RNA-seq data for 3 untreated IMR90 cells versus 3 Doxorubicin-treated IMR90 cells (senescent) versus 3 Doxorubicin +MDL72527 treated IMR90 cells