GSE104274
SETD5 is a H3K36 methyltransferase which preserves transcriptional fidelity during brain development and neuronal wiring [ChIP-seq]
We assess the epigenetic function of Setd5 in mouse neural stem cells (NSCs), by profiling a panel of histone modifications and Setd5 binding in wild type and Setd5 heterozygous NSCs. Overall design: ChIP-seq for H3K4me3, H3K4me1, H3K27ac, H3K27me3, H3K36me2, H3K36me3 in wild type and Setd5+/- NSCs and ChIP-seq for SETD5-V5 in wild type NSCs.