GSE125741
Effect of apicidin on gene expression in Staphylococcus aureus USA300 strain LAC
The fungal metabolite apicidin acts as a quorum sensing inhibitor in Staphylococcus aureus. Here we use RNA-sequencing to examine the effect of apicidin on gene expression, comparing to untreated wild-type and an agr quorum sensing mutant. Overall design: Illumina RNA-sequencing of S. aureus USA300 LAC and LAC ?agr +/- 100 µM apicidin, in triplicate.