GSE132913
The major pre- and post-menopausal estrogens play opposing roles in obesity driven mammary inflammation and breast cancer development
Purpose: The goals of this study : Estrone(E1) vs Estradial (E2) in breast cancer inflammatory signaling and breast cancer progression.  Is HSD17B14 that convert E2 to E1 the oncogene. Overall design: RNA seq : 1)CFBS,E1 Vs E2 at 10nM treatment to MCF7.2)cFBS,T, T+E1 Vs T+E2. 3)Control Vs HSD17B14. 4) E1,HSD17B14 +E2, HSD17B14 +E1 Vs E2