ena-STUDY-ROBERT KOCH INSTITUTE-22-02-2017-16:23:45:989-89
Functional analysis of the alternative sigma-28 factor FliA and its anti sigma factor FlgM of the non-flagellated Legionella species L. oakridgensis
A less virulent Legionella species, L. oakridgensis is causing the Legionnaires' disease and is known to not have flagella, even though, L. oakridgensis has the regulator of flagellin expression (FliA). This protein has been shown to be involved in the expression of virulence factors. Thus, in this investigation the strain was chosen to search for FliA target genes and to identify putative virulence factors of L. oakridgensis.
A less virulent Legionella species, L. oakridgensis is causing the Legionnaires' disease and is known to not have flagella, even though, L. oakridgensis has the regulator of flagellin expression (FliA). This protein has been shown to be involved in the expression of virulence factors. Thus, in this investigation the strain was chosen to search for FliA target genes and to identify putative virulence factors of L. oakridgensis.