GSE133387
H3K27ac ChIP-seq in LNCaP cell line overexpressing WT or mutant FOXA1
Our data suggested  that FKHD-MSs impair the chromatin binding of FOXA1 to AR-dependent enhancers and thus suppress AR transcriptional activity, and promote PCa progression through increasing FOXA1 binding to a subset of AR-independent enhancers that regulates transcription of genes mediating EMT and metastasis Overall design: We generated LNCaP stable cells with tetracycline-inducible expression of V5-tagged FKHD-MSs or WT FOXA1. H3K27ac ChIP-seq experiments were performed on these cell lines