GSE158451
IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis.
Igf1r signaling is required in fibroblasts to drive the formation of new alveoli, and those activities is depend upon its regulation on mechanical property of myofibroblasts via an Akt/Yap mechanism. Overall design: RNA-Seq analysis of FACS sorted Rosa-EGFP cells from P6 lungs after Igf1r was deleted at P0 by Gli1creER.