GSE184427
RNA seq analysis of LuCaP Prostate Cancer Patient-Derived Xenografts
We assembled a prostate xenograft interactome from a large data set with 128 RNA sequencing expression profiles generated through administration of 13 small molecule perturbagens in vivo to 5 distinct and genetically diverse LuCaP xenograft lines (LuCaP 73, LuCaP77, LuCaP 78, LuCaP 81, LuCaP 147), with half of the xenograft samples collected from hosts castrated for 1 week. Overall design: Gene expression profiles were obtained from LuCaP series human prostate cancer xenograft lines treated with one of 13 perturbagens in non-castrated and and castrated hosts.