PRJNA446027
Recurrent homozygous deletion of DROSHA and duplication of DUF1220 domain in Pineoblastoma
Pineoblastoma is a rare and highly aggressive brain cancer of childhood. Here we report the genomics of pineoblastoma evidencing recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP containing the ancestral DUF1220 domain.