PRJNA802807
GSDME-mediated Pyroptosis Promotes Atherosclerosis
Ablation of GSDME in macrophages represses ox-LDL induced inflammation and macrophage pyroptosis.This study reveals a novel role of GSDME-mediated pyroptosis in the progression of atherosclerosis and transcriptional mechanisms of GSDME, which represents a promising therapeutic approach for atherosclerosis.