phs002681
Natural Killer Cell Therapies for Hematologic Malignancies
The "Natural Killer Cell and Lymphocyte-Targeted Immunotherapies in Cancer" study is an umbrella repository for data pertaining to multiple clinical trials that aim to assess NK cell and lymphocyte-targeted immunotherapy strategies across cancer types. Here, data from three trials, NCT03068819, NCT02782546, and NCT03687957 are presented.Cytokine Induced Memory-like NK Cell Adoptive Therapy for Relapsed AML after Allogeneic Hematopoietic Cell Transplant in Children and Adults (NCT03068819)Pediatric and young adult (YA) patients with acute myeloid leukemia (AML) who relapse after allogeneic hematopoietic cell transplantation (HCT) have extremely poor prognosis. Standard salvage chemotherapy and donor lymphocyte infusions (DLI) have little curative potential. Previous studies showed that... (for more see dbGaP study page.)