GSE158085
Novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells
We report differential gene expression changes by withaferin A in breast cancer cells versus a normal mammary epithelial cell line. Overall design: Examination of withaferin A-regulated transcriptome in a normal mammary epithelial cell line (MCF-10A) and human breast cancer cells belonging to different subtypes including MCF-7 (luminal type), SK-BR-3 (HER2 enriched type), and MDA-MB-231 (basal type).