GSE108341
ICAMs are not obligatory for functional immune synapses between naïve CD4 T cells and lymph node DCs
The quantitative deep bulk MARS-seq analysis demonstrated that DCs from ICAM-1/2 double knockout (DKO) chimeric LNs  display similar transcriptomes to those of WT DCs in both their resting and CD40 mAb activated states. Overall design: Transciptome analysis of activated and resting classical DCs from either WT or ICAM-1/2 DKO chimeric mice was performed. DC cells were isolated from popliteal lymph nodes and sorted according to the following markers: CD45, CD11c and MHC-II