PRJNA728216
Transcriptional analysis of HT-29 cells stimulated by spore-displayed p75
A Lactobacillus rhamnosus GG-derived protein, p75, is one of key molecules exhibiting probiotic activity. However, the molecular mechanism and transcriptional response of p75 in human intestinal epithelial cells are not completely understood. To gain a deeper understanding of its probiotic action, this study investigated genome-wide responses of HT-29 cells to stimulation by spore-displayed p75 (CotG-p75) through a transcriptome analysis based on RNA-sequencing (RNA-seq).