Mouse_PLX_resistant_tumours-sc-2013-05-09T11:05:42Z-2620
Mouse_PLX_resistant_tumours
In this project we have generated a set of mouse Braf driven melanomas that are are resistant to the Braf inhibitor PLX4032. Here we sequence the exome of these tumours to search for mutations that allow these tumours to grow in spite of the drug.   This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
In this project we have generated a set of mouse Braf driven melanomas that are are resistant to the Braf inhibitor PLX4032. Here we sequence the exome of these tumours to search for mutations that allow these tumours to grow in spite of the drug.