GSE178306
Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia [RNA-seq]
Identification of gene expression changes induced by glutamine deprivation in melanoma cells lacking various epigenetic regulators Overall design: RNA-seq analysis of melanoma cells expressing 4-7sgRNAs targeting members of the PRC2 complex (EED, EZH2, SUZ12), histone H1B (HIST1H1B), the chromatin remodeller SMARCD1 and a non-expressed control gene (TNP2), and grown in either unperturbed conditions (d0) or under glutamine deprivation (d12).