PRJNA453827
Huntington BACHDxNG2 study
This study is to investigate whether the oligodendroglial (OL) pathology and myelination deficits in Huntington disease (HD) are the result of cell intrinsic effects of mutant HTT in oligodendroglia or secondary to neuronal pathology using a NG2-Cre mouse line to a flox'ed mutant HTT mouse (BACHD) mice.