GSE137827
RNA Sequencing  Analysis of macrophages from Wild Type and Gsdmd-/- colitis mice
We identified that GSDMD protected against DDS-induced colitis, and GSDMD deficiency in macrophages promoted the development of DSS-induced colitis.The purpose of this experiment was to identify how GSDMD protected against DSS-induced colitis. Overall design: Macrophages mRNA profiles of wild type (WT) and Gsdmd-/- mice with colitis were generated by deep sequencing, in triplicate, using BGISEQ-500