GSE130886
Effect of IL6 inhibition on the gene expression of erythroid progenitors in aged mice
Gene expression analysis has revealed that Interleukin-6 signalling in murine erythroid progenitors is altered during ageing. Here we study the impact of inhibition of IL6 on the transcription profile of progenitors from bone marrow in aged mice Overall design: Aged mice (24-25 months) were treated with anti-IL6 antibody or IgG control and examine the gene expression of erythorid progenitors by bulk (100 cells) RNA-seq