PRJNA801468
Hirschsprung's disease exosomal microRNAs sequencing
Hirschsprung's disease, a congential disorder characterized by spasticity and narrowing of the distal colon , as well as abnormalities in peristalsis and defecation, is caused by a deficit if ganglion cells in the distal colon. This study aimed ti find key microRNAs and their associated genes from plasma-derived exosomes, as potential biomarkers to study HSCR pathogenesis