MAPS_HCC_pilot
Massive anchored parallel sequencing (MAPS) for genome-wide integrome analysis
We developed the massive anchored parallel sequencing (MAPS) approach to isolate and sequence integrants. Using the example for the multiplex analysis of virus-host integrations in hepatocellular carcinoma patients with hepatitis B virus (HBV) infections, we demonstrated that MAPS could isolate and characterize clonal populations of HBV integration events.