GSE121315
Effect of Neutrophil Extracellular Traps and Psoriasis-Associated TRAF3IP2 Genotype on Induction of Human Th17 Cells
Using RNA-sesq to assess effects of NET exposure under different activation conditions, and assessing effects of homozygosity vs. nullizygosity for the Act1 D10N genotype Overall design: PBMC from 12 different individuals of known Act1 genotype were subjected to 4 conditions (Control; CD3/CD28; NET; NET+LPS) at 2 different times (0h and 6h PMA/lonomycin).