GSE174189
Estrogen Receptor Regulated Gene Signatures in Invasive Breast Cancer Cells and Aggressive Breast Tumors
When co-activated with IKKß, estrogen receptor regulates a subset of genes in invasive cells, which are associated with proliferation, vesicle and intracellular trafficking. These genes are associated with poor survival in patients and are enriched in metastatic tumors in PDX models. Overall design: scRNA-seq (OneCellBio) and bulk RNA-seq