GSE119013
Effect for target mRNA degradation by methylated microRNAs
To confirme the function of methylated micro RNAs (miR-17 and let-7a), we transfected methylated or non-methylated microRNAs to DICER KO HCT116 cell line. mRNA were isolated at 48 houes after transfection. This data show that the function were different between methylated or non-methylated microRNAs. Overall design: Methyated or non-methyated microRNAs were transfected in dicer KO HCT116 cell lines.