GSE136069
Expression data from D. melanogaster whole guts or intestinal progenitor cells isolated from flies mock infected or infected with wild type Vibrio cholerae (C6706) or type VI secretion system deficient Vibrio cholerae (C6706?vasK)
We used RNA-seq to determine transcriptional profiles of whole guts or IPCs isolated from guts infected with wild type or type VI secretion system deficient Vibrio cholerae. We found significant differences between guts and progenitor cells infected wild type or type VI secretion system deficient Vibrio cholerae. Overall design: Newly eclosed female flies were raised for 5 days at 29C and then mock infected (with sterile bacterial growth media) or infected with wild Vibrio cholerae (C6706) or type VI secretion system deficient Vibrio cholerae for 24 hours. After 24 hours guts were dissected. The transcriptome of whole guts or intestinal progenitor cells only was sequenced.