DNA Ligand Evolution-sc-2010-07-19
DNA Ligand Evolution
DNA Ligand evolution - random pool of oligos, all with Illumina-compatible ends, allowed to bind to thrombin. The complexes are separated from the excess oligos, eluted, amplified and exposed to protein target again. Aliquots are removed after each cycle for sequencing.
DNA Ligand evolution - random pool of oligos, all with Illumina-compatible ends, allowed to bind to thrombin. The complexes are separated from the excess oligos, eluted, amplified and exposed to protein target again. Aliquots are removed after each cycle for sequencing.