GSE111024
Extensive recovery of embryonic enhancer and gene memory stored in hypomethylated enhancer DNA.
To understand how dynamics of enhancer features correlates with gene expression in adult tissue and during development, we analyzed histone modifications, chromatin accesibility, DNA methylation and gene expression at multiple time points during mouse development and adult mice. Overall design: We conducted RNA-seq, ATAC-seq, ChIP-seq, and WGBS experiments using purified intestinal epithleal cells from mouse embryos and adult cells.