PRJNA480674
mmunoglobulin G Selectively Identifies Pathobionts in Pediatric Inflammatory Bowel Diseases
We hypothesized host immunoglobulin (Ig)G can be used to identify bacteria involved in IBD pathogenesis. IgG-bound and -unbound microorganisms were collected from 39 pediatric terminal ileum aspirate washes [non-IBD (n=10), CD (n=15), and UC (n=9)] and composition was assessed by next generation sequencing.