ena-STUDY-HELMHOLTZ CENTRE FOR INFECTION RESEARCH-28-03-2017-12:37:51:174-13
The vaginal and urinary microbiota in health, during BV and after treatment
The urinary and vaginal fluid microbiota was analysed using sequencing of the rRNA gene V1-V2 regions. Vaginal fluid and urine samples were taken from women with bacterial vaginosis (BV) and analysed throughout the course of a clinical study that aimed at characterising the effect of a newly developed pessary containing an amphoteric tenside compared to a pessary containing lactic acid. Before participating women received either pessary, theywere first treated with the antibiotic metronidazole. Vaginal fluid samples were taken and analysed at five different time points thoughout the study. Urine samples were taken and analyed before and after metronidazole treatment. As healthy control groups, vaginal fluid samples were taken and analysed from healthy women and urine samples from healthy men and women.
The urinary and vaginal fluid microbiota was analysed using sequencing of the rRNA gene V1-V2 regions. Vaginal fluid and urine samples were taken from women with bacterial vaginosis (BV) and analysed throughout the course of a clinical study that aimed at characterising the effect of a newly developed pessary containing an amphoteric tenside compared to a pessary containing lactic acid. Before participating women received either pessary, theywere first treated with the antibiotic metronidazole. Vaginal fluid samples were taken and analysed at five different time points thoughout the study. Urine samples were taken and analyed before and after metronidazole treatment. As healthy control groups, vaginal fluid samples were taken and analysed from healthy women and urine samples from healthy men and women.