DNA_methylationand_gene_expression_in_Polistes-sc-2013-03-01T14:09:18Z-2554
DNA_methylationand_gene_expression_in_Polistes
In this study we aim to assess the epigenetic and genome-wide expression changes accompanying caste differentiation in brain of the Polistes Paper Wasps. All the samples (16) are genome-wide ligation based proximity samples, as described in thes publication: Methods. 2012 Nov;58(3):268-76 and PLoS One. 2011;6(10):e26426.   These data are part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
We will associate gene expression changes with DNA methylation pattern in brain of  Queen and Worker castes of  Polistes canadensis Paper wasps. Paper wasps  primitive social organisation shows higher phenotype plasticity at adult stage compare to highly social organisation of bees (Patalano et al., Curr Opin Cell Biol. 2012 Jun;24(3):367-73). DNA methylation has been previously show to play a role in Worker versus Queen differentiation during larva stage (Kucharski et al., Science. 2008 Mar 28;319(5871):1827-3)but no study has yet associated the dynamic changes of DNA methylation and  gene expression with adult behaviour.