GSE98300
Genome-wide transcriptional and epigenomic map of primary and metastatic Sonic Hedgehog subgroup medulloblastomas
We report findings that illuminate a dynamic metastasis pathway in the common pediatric brain tumor medulloblastoma. Overall design: We examined binding states of H3K27ac and ATOH1 in primary and metastatic medulloblastoma driven by ATOH1 in collaboration with aberrant Sonic Hedgehog (SHH) signaling.