PRJNA827179
Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity
C. albicans immunogenicity during colonization requires dynamic gene expression. Oscillating UME6 expression supports C. albicans-induced Th17 immunogenicity. Intestinal fungal beta-glucan and mannan stimulate systemic Th17 immunogenicity. Th17 immunogenicity requires signaling via multiple pattern recognition receptors.