GSE122079
Transcriptomic analysis of senescent cells treated with Cardiac glycosides
IMR90 ER:RAS cells were treated with 4OHT to induce senescence. 6 days later they were treated with Vehicle, Ouabain or Digoxin for 16 or 36h and collected he cells were collected for total mRNA analysis. Minus (Cell not treated with 4OHT), Plus (Cell treated with 4OHT and vehicle), Plus C (On to pof the aforementiones treatments, cells were treated with Caspase inhibitors O/N) Overall design: 12 conditions were examined