GSE182840
Regulation of group 3 innate lymphoid cells by Setd2 [RNAseqILC3]
To determine the molecular regulation of different subsets of ILC3s by Setd2, small intestinal NKp46- ILC3s (Thy1highCD45low NKp46-) and NKp46+ ILC3s (Thy1highCD45low NKp46+) from Setd2-deficient and control mice were subjected to assay for RNA-seq. Overall design: Biological duplicates of 500000 ILC3s sorted by flow cytometry from the small intestine of 8 week old Rag1-/-;Setd2f/f or Rag1-/-;Rorc-cre;Setd2f/f mice were subjected to RNA-seq analysis.