PRJNA672682
The effect of Human Milk Oligosaccharides on the fecal microbiome in visceral hypersensitivity mouse models
Pain-related functional gastrointestinal disorders (FGIDs), including infantile colic, are characterized by visceral hypersensitivity (VHS) associated with alterations in the microbiota-gut-brain axis. Since human milk oligosaccharides (HMOs) modulate microbiota, gut and brain functions, we investigated whether HMOs decrease VHS in mice and explored the potential role of the microbiota.