GSE134264
Natural killer cells suppress T cell tumor immune evasion [Supernatant treated control or Jak1 sgRNA B16-F10 RNA Seq]
Investigation of the transcriptional response in Jak1 depleted tumor cells upon NK-derived cytokine presence using 3' RNA sequencing Overall design: Control or Jak1 sgRNA B16-F10 tumor cells were treated for 7 hours with supernatant derived from a separate WT B16-F10/NK co-culture. Experiment was performed in technical triplicate. Cells treated with IFN-? were used as a positive control and cells treated with TNF were used as a negative control