GSE136365
Genome-wide maps of double-strand breaks
Mapping physiological double strand breaks (DSBs) in cancer cells uncovers transcription-coupled repair mechanism at oncogenic super-enhancers in which RAD51 of the homologous recombination pathway plays a key role supporting the hyper-transcription of related oncogenes. Overall design: Examination of changes in DSBs profiles in MCF7 cells upon different treatments and manipulations