GSE191005
Gene expression changes after chemical knockout of ENL in Molm13 cells
ENL is required for expression of MLL1-target genes as well as the aberrant gene expression in MLL1-r leukemia. We investigated the gene expression changes after selective chemical knockout of ENL in leukemia cells. Overall design: Molm-13 cells containing MLL-AF9 gene were treated with Cpd-1 for 4 days, and gene expression changes were evaluated.