GSE171227
Next Generation Sequencing Facilitates Quantitative Analysis of U87 Transcriptomes to define the ALKBH5-dependent hypoxia-induced genes
Among 720 hypoxia-induced genes (at least 2 folds of upregulation in Hypoxia-treated U87 WT or shScr cells compared with Normoxia), the expression of 35 genes is significantly suppressed by ALKBH5 depletion (U87 Hypoxia shALKBH5/shScr) Overall design: The mRNA profiles of U87 WT-Normoxia, U87 WT-Hypoxia, U87 shScr-Hypoxia and U87 shALKBH5-Hypoxia