7ae51051-0e02-44a0-9538-33d2723f26f4
Novel ICE in MDR H influenzae
A multidrug-resistant (MDR) strain of Haemophilus influenzae, Hi-228, with phenotypic resistance towards ampicillin, cefotaxime, chloramphenicol, gentamicin, and azithromycin, was characterized. Hi-228 carries a novel integrative and conjugative element (ICE), Tn7100, contributing to this remarkable and previously unreported MDR profile. Tn7100 contains two novel transposable elements, Tn7470 and Tn7471, with high sequence identities to a plasmid in Enterobacterales and an ICE in streptococcal species, respectively.
A multidrug-resistant (MDR) strain of Haemophilus influenzae, Hi-228, with phenotypic resistance towards ampicillin, cefotaxime, chloramphenicol, gentamicin, and azithromycin, was characterized. Hi-228 carries a novel integrative and conjugative element (ICE), Tn7100, contributing to this remarkable and previously unreported MDR profile. Tn7100 contains two novel transposable elements, Tn7470 and Tn7471, with high sequence identities to a plasmid in Enterobacterales and an ICE in streptococcal species, respectively.