GSE128526
Aberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cells
Analysis of PIWIL1 function in COLO205 [ATCC® CCL-222] colon adenocarcinoma cancer cell culture model. Overall design: Total Small RNAs and small RNAs co-immunoprecipitated with PIWIL1 from COLO205 cells were analyzed for piRNA signatures. Total RNA sequencing from PIWIL1 short hairpin knock-downs and CRISPR-generated knockouts were used for differential gene and transposon expression.