GSE161729
Single cell RNA-seq for GATA-1 wildtype and 2RA mutation Knockin mice bone marrow
Purpose: To compare bone marrow cell population and gene regulation changes in GATA-1 mutation Knockin mice compared with wild type mice Methods: Flow cytometry sorting mouse bone marrow cells (Lin- Kit+) from GATA-1 mutation Knockin mice and wild type mice were collected and performed single cell RNAseq analysis Results: cell population and gene regulation changes in GATA-1 mutation Knockin mice and wild type mice bone marrow cells were compared Overall design: compare bone marrow cell population and gene regulation changes in GATA-1 mutation Knockin mice compared with wild type mice