GSE158294
Impact of transcription factor ETV1 on HCT116 colon cancer cells.
We identified that ETV1 downregulation affects growth of HCT116 cells, and concomitantly affects their transcriptome. This suggests that ETV1 might be involved in colon cancer formation and/or progression. Overall design: HCT116 cells were infected with retrovirus expressing control shRNA or two different ETV1 shRNAs (#1 and #5). RNA was extracted and subjected to RNA-sequencing.