GSE113541
mRNA profiles of WT and STAT6-/- mice colon tissue
Colon tissues from 6-8 week BALB/c mice and STAT6-/- mice having 3% DSS for 3 days were obtained. Total RNAs were isolated with Trizol (invitrogen) and the RNA-seq library was prepared by the Beijing Genomics Institute. Sequence reads were obtained using BGIseq500 and successfully mapped to mouse genome. Reads counts were normalized based on FPKM, fold changes were calculated for all possible comparisons. Overall design: Gene expression of colon tissue of 3% DSS treated WT and STAT6-/- mice