PRJNA448170
Environmental dependence testing on recombination in Streptococcus pneumoniae
Bacteria reproduce in a different way to humans, which involves exactly copying their genomes into daughter cells with a few mutations/mistakes. This means that bacteria shuffle their genes far less often than humans do and genes or traits are more directly linked with the singular bacterial parent cell rather than the two parents that are involved in sexual reproduction. However, bacteria do occasionally have sex in the form of homologous recombination by taking up external DNA and incorporating it into their genomes. This happens far less regularly than sexual reproduction happens in human generations but is a known way that bacteria undergo 'Horizontal gene transfer'. This means that genes can be acquired without being inherited. In this study we show that this form of horizontal gene transfer is more likely to happen in certain environments over others in Streptococcus pneumoniae. In particular, we show that this is more likely to happen in environments that closely mirror the nasopharynx which is the natural environment that S. pneumoniae lives in.