GSE158642
The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation [HiChIP]
A deep-learning framework interprets multi-omic data across epidermal differentiation, identifying cooperative DNA sequence rules that regulate gene modules. Massively parallel reporter analysis validates temporal dynamics and cis-regulatory logic. Overall design: HiChIP (Mumbach 2016) collected at days 0, 3, and 6 during in vitro keratinocyte differentiation