8d57f560-9ffd-4c01-b4b0-2041f37acb26
Tamoxifen-induced acute deletion of the MALT1 paracaspase function in regulatory T cells.
The floxed allele in Malt1fl/PM;Foxp3eGFP-Cre-ERT2 (PM) or Malt1fl/+;Foxp3eGFP-Cre-ERT2 (WT) control mice was deleted by tamoxifen administration. Subsequently, 1000 CD4+EGFP+ Tregs were sorted into a 96-well plate and analyzed by RNA sequencing technology. The study comprised biological replicates (BR) plus technical replicates (TR).
The floxed allele in Malt1fl/PM;Foxp3eGFP-Cre-ERT2 (PM) or Malt1fl/+;Foxp3eGFP-Cre-ERT2 (WT) control mice was deleted by tamoxifen administration. Subsequently, 1000 CD4+EGFP+ Tregs were sorted into a 96-well plate and analyzed by RNA sequencing technology. The study comprised biological replicates (BR) plus technical replicates (TR).