GSE110595
Upregulation of TFH profile in absence of Ets1 expression
To characterize the effect of loss of Ets1 in Non-TFH and TFH cells, we performed gene expression RNAseq analysis for T follicular helper (TFH) and Non-T follicular helper (Non-TFH) cells in WT (Ets1 fl/fl) and Ets1 KO (CD4-cre Ets1 fl/fl) mice. Overall design: Total RNA was extracted from splenic CD4+CXCR5+PD-1+ TFH and CD4+CXCR5-PD-1- Non-TFH cells in Ets1 fl/fl and CD4-cre Ets1 fl/fl mice and analyzed by RNA-seq.