GSE139091
Hemopexin is a novel tumor suppressor that blocks cancer metastasis by modulating heme:DNA G-quadruplex dynamics to control c-myc expression
Treamtent of PC3 prostate cancer cell line results in enhanced colony growth and c-myc expression. Further, heme promotes tumro growth and metasease in in vivo models of carcinogenesis Overall design: PC3 cells were treated for 2 and 4 hours with heme and the gene expression was measured by RNA-seq.