GSE138780
Discrete Adaptive Responses to MEK Inhibitor In Subpopulations of Triple-Negative Breast Cancer [RNA-seq]
We characterize gene expression in epithelial and mesenchymal subpopulations isolated from a triple-negative breast cancer cell line in response to trametinib treatment. Overall design: We isolated EpCAM+ CD49f+ (POS) and EpCAM- CD49f- (NEG) isolated subpopulations by FACS, then performed RNA-seq following treatment as indicated