GSE201309
Effects of matrine on gene expression of myeloid leukemia cells
To investigate the molecular mechanism of matrine's anti-myeloid leukemia effect, Acute myeloid leukemia cells HL-60 and U937 and chronic myeloid leukemia cells K562 were treated with 0.8mg/mL matrine for 30min and 24h, respectively. Then, RNA-Seq data before and after matrine treatment were used for gene expression profile analysis Overall design: Comparative gene expression profile analysis of RNA-Seq data of myeloid leukemia cells before and after matrine treatment