GSE137204
Impact Of Oil Spill To Human Lung Health – Next Generation Sequencing And Mouse Model Based Analysis
This project addresses the question of impact of oil spills on lung health. Specifically the project will address the general hypothesis, which is upon oil/dispersant respiratory exposure there will be a higher carcinogenic potential of lung tissue. Overall design: Wild-type C57BL/6 (B6) mice were exposed to  BP crude oil, dispersant Corexit 9500, dispersant Corexit 9527, oil + 9527, oil + 9500 and saline (as control) using intratracheal instillation method for 2 weeks. Each treatment (exposure) group contains 3 female and 3 male mice. Treatment of male and female mice were performed separately.