GSE135495
Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection [RNA-seq]
scRNA-seq of CD45+ leukocytes isolated from WT and triple mutant-infected mice identified several genes with concordant changes in H3Ac status and transcriptional expression. Overall design: Live, CD45+ leukocytes were isolated by FACs from implant-associated tissue at day 14-post infection for scRNA-seq.  While these samples were prepared  and sequenced for single-cell RNA-seq, they were analyzed as bulk RNA for this study.  All raw data for a single-cell analysis have been included.