GSE159279
Antigen Presentation-Independent Reciprocal Immune Modulation by HLA-DRB1 Allelic Epitopes that Associate with Autoimmune Disease Risk or Protection in Human Macrophages
We report RNA sequencing data that shows the the differential effects of HLA-DRb1*0401 (SE) and HLA-DRb1*0402 (PE) on marcophage gene expression under M1 polarizing cell culture conditions Overall design: mRNA profiles obtained from human macrophages cultured in presence of synthetic peptides coding the 65-79 region of HLA-DRb1*0401 (SE) or HLA-DRb*0402 (PE) and IFNy