splat_scwgbs
scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation
We present single cell Splinted Ligation Adapter Tagging (scSPLAT). scSPLAT employs a pooling strategy to facilitate sample preparation at higher scale and throughput. We demonstrate the accuracy and robustness of the method by analyzing single cell methylation data obtained from single K562 cells and from single liver nuclei.
We present single cell Splinted Ligation Adapter Tagging (scSPLAT). scSPLAT employs a pooling strategy to facilitate sample preparation at higher scale and throughput. We demonstrate the accuracy and robustness of the method by analyzing single cell methylation data obtained from single K562 cells and from single liver nuclei.