PRJNA530044
Whole genome methylation of cloned animals
To identify the cause of phenotypic abnormality of the cloned sow and detect the epigenetic variation between the cloned pigs and donor pigs, we performed a whole-genome bisulphite sequencing (WGBS) for the cloned pig and donor pig to reveal the changes in epigenetic mechanism between two pigs. Then, we analysed the effect of clone technology on cloned animal epigenetics. The study could provide reference recommendations for livestock cloning production.