GSE185071
RNA-seq quantification in EPS15 knockdown and scramble-oligo controls in JEG3 cells
Purpose: The goals of this study are to compare transcriptomic profiles of JEG-3 cells in EPS15 knockdown and control cells. Methods: EPS15 scramble oligos were used as a negative control, while an siRNA targetting EPS15 was used to generate knockdown cell lines. Results: Using an optimized data pipeline, we quantified mRNA expression of 37,788 genes and detected differentially-expressed genes across knockdown and control cell lines. Conclusions: Our results provide some experimental evidence that EPS15 has transcriptomic consequences in human placenta-derived JEG3 cells. Overall design: mRNA profiles of EPS15 knockdown JEG-3 cells and control cells