GSE157790
KLF3 promotes the 8-cell-like transcriptional state in pluripotent stem cells
This study identifies previously unrecognized heterogeneity due to KLF3 protein expression in mESCs. Overall design: Examination of differential expressed genes between KLF3-GFP positive and KLF3-GFP negative / GFP and KLF3 over expressing mouse embryonic stem cells grown in normal ES culture media by Smart-seq2 and poly(A)+ RNA-Seq separately. Two biological replicates were completed for each groups.