ena-STUDY-Institute of Microbiology of the Czech Academy of Sciences, v.v.i.-23-10-2020-15:40:36:181-203
Transcriptional response of B. pertussis Tohama I to blood exposure
Here we studied transcriptome of B. pertussis Tohama I during growth on charcoal agar plates with/without blood and subsequently subcultured in liquid media. We found that B. pertussis Tohama I actively adapts to the presence of blood in the medium leading to global changes in gene expression. Most prominent de-regulation was observed for genes linked to regulatory, metabolic and virulence functions.
Here we studied transcriptome of B. pertussis Tohama I during growth on charcoal agar plates with/without blood and subsequently subcultured in liquid media. We found that B. pertussis Tohama I actively adapts to the presence of blood in the medium leading to global changes in gene expression. Most prominent de-regulation was observed for genes linked to regulatory, metabolic and virulence functions.