GSE168348
Gene expression analyses of whole ovaries from mice that were treated with N-Cadherin antagonist CRS-006
N-Cadherin is a cell surface protein that is critical for cell-cell adhesion and is essential for structural integrity of tissues. In the ovary, it is expressed by granulosa cells and cumulus cells junctions throughout ovarian development. Importantly, it is also present between oocyte (egg) and surround cumulus cells, and is the only physical type of communication that is present between the egg and its surrounding cells. Overall design: RNA-seq was performed on ovaries for either CRS-066 treated (N= 5) or vehicle treated  (N=6)mice for comparitve analyses