GSE173612
10X single-cell RNASeq profiling of immune infiltrate from mutant IDH1 ICC tumors treated with AG120 (mIDH1 inhibitor) or vehicle
AG120, mIDH1 inhibitor, has an immune-dependent mechanism. Single-cell RNA sequencing was used to profile the tumor microenvironment and the key immune subsets impacted by the inhibitor. Overall design: Profiling of immune infiltrate from mIDH1 ICC treated with AG120 or Vehicle.