GSE185118
MicroRNA sequencing of plasma-derived exosomes from LLC tumor-bearing mice
We report the role of leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4)/gp49B in the regulation of  exosomal miRNA composition in tumor-bearing mice by next-generation sequencing Overall design: WT and gp49B deficiency mice were inoculated with Lewis Lung Cancer (LLC) cells by intravenous injection. After inoculation, LLC--bearing mice were sacrificed on day 21, and plasma samples were harvested for exosome isolation. miRNA contents in plasma-derived exosome were anlyzed using an Illumina NextSeq-500 Sequencing System (Illumina, San Diego, CA, USA).