GSE162583
mRNASeq of kidney, liver, and cerebellum of P195A/p150- and P195A/p150+ mice
The goal of this experiement was to determine what transcriptional differences there are between P195A/p150- (sick) and P195A/p150+ (healthy) mice. Kidney, Liver, and Cerebellum were the most clearly affected on histology and qPCR for IFN. We found an IFN signature and ISR signature were both upregulated in P195A/p150- mice as compared to P195A/p150+ littermates. Overall design: mRNA profiles of the liver, kidney, and cerebellum of 23 day old P195A/p150- and P195A/p150+ mice