GSE112201
RNA Misplicing in Fuchs Endothelial Corneal Dystrophy II
RNA-Seq splicing data from the  corneal endothelia of FECD patients and controls reveal hundreds of differential alternative splicing events. These include events previously characterized in the context of myotonic dystrophy type 1 and epithelial-to-mesenchymal transition, as well  as splicing changes in genes related to proposed mechanisms of FECD pathogenesis. Overall design: RNA-Seq was used to compare corneal endothelial specimens from subjects with Fuchs endothelial corneal dystrophy. Control samples from normal subjects were also provided.