GSE169215
MiRNAs sequence  of macrophages derived exosoms in WT group and Roquin-1 san:san group.
We reported the function of Roquin-1 in the miRNA-sorting of macrophages derived exosomes. At first, we used the supernatant of 929 cells to culture the bone marrow derived macrophages (BMDM) from bone marrow cells of WT and Roquin-1 san:san mice. Then, we isolated the macrophages derived exosomes by ultracentrifugation. At last, we performed Next-generation sequencing to detect the differences of miRNA-sorting between WT and Roquin-1 macrophages derived exosomes. Overall design: miRNA profiles of macrophages derived exosomes in WT and Roquin-1 san:san mice [contributor]  Nanjing Medical University