E-MTAB-9009
RNA-seq of liver biopsies of eIF6 wild type and eIF6 heterozygous mice
A cohort of age-matched mice (eIF6+/+ and  eIF6+/-) were fed with High-Fat Diet. All experimental mice were sacrificed after 16 weeks and the livers were recovered. RNA was isolated from liver biopsies of eIF6+/+ and eIF6+/- mice  and RNAseq analysis was performed. The aim of the analysis is the investigation of the transcriptional changes  driven by chronic depletion of eIF6  in the liver of mice upon High Fat Diet (HFD) feeding.
A cohort of age-matched mice (eIF6+/+ and  eIF6+/-) were fed with High-Fat Diet. All experimental mice were sacrificed after 16 weeks and the livers were recovered. RNA was isolated from liver biopsies of eIF6+/+ and eIF6+/- mice  and RNAseq analysis was performed. The aim of the analysis is the investigation of the transcriptional changes  driven by chronic depletion of eIF6  in the liver of mice upon High Fat Diet (HFD) feeding.