GSE159342
Transcriptional analysis of LAG3 deficient Tregs in an inflamed CNS
Transcriptonal analysis of Tregs reveal role of LAG3 in stability and function of Tregs in an inflamed CNS Overall design: CD45+ cells or CD4 cells were sorted from CNS cells isolated at peaks of diseases in age and sex matched mice(Lag3KO and WT) in which EAE was induced were subject to Gene Expression analysis using the 10x Genomics Single Cell analysis platform.