a8a5d62e-9c1f-42b3-8433-a1603f6e65d0
Gut microbiota linked to arterial stiffness
In this study, we analyzed the correlation of gut microbiome composition and functional capacity with arterial stiffness, evaluated by the brachial-ankle pulse wave velocity (baPWV), among 96 patients with hypertension aged 40-65 years. Our data showed that the characteristics of gut microbiome were altered in participants with elevated arterial stiffness compared with participants without arterial stiffness. Gut microbial diversity had a declined tendency associated with the severity arterial stiffness. Moreover, the gut microbiome composition was significantly changed with the progression of arterial stiffness during a median 2.6 years of follow-up.
In this study, we analyzed the correlation of gut microbiome composition and functional capacity with arterial stiffness, evaluated by the brachial-ankle pulse wave velocity (baPWV), among 96 patients with hypertension aged 40-65 years. Our data showed that the characteristics of gut microbiome were altered in participants with elevated arterial stiffness compared with participants without arterial stiffness. Gut microbial diversity had a declined tendency associated with the severity arterial stiffness. Moreover, the gut microbiome composition was significantly changed with the progression of arterial stiffness during a median 2.6 years of follow-up.