GSE98197
Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis
Our mouse model (Ksp-CreER/Sav1fl/fl ) offers novel insights into molecular events that are linked to fibrosis development from Sav1 loss. Overall design: RNAseq analysis was performed on cortex tissue from mouse kidneys with and without Sav1 loss.