phs001366
Next-generation Sequencing of Small Cell Lung Cancer to Identify Actionable Targets for Treatment
In this prospective study, custom genome-wide exome and whole transcriptome sequencing (NGS) was used to identify genomic events and associated expression changes in advanced Small Cell Lung Cancer (SCLC) and attempt to prescribe systemic therapy based on the results. Tumor and normal pairs were sequenced from 12 patients with advanced SCLC for this study.