GSE111324
Drosophila esc mutants show Hox-derepression along the AP axis in CNS
Mutating esc (extra sex-combs), maternal and zygotic, leads to loss of H3K27me3 and affects Hox-patterning along the AP-axis in neurogenesis Overall design: Control (OregonR) flies are compared to esc-maternal zygotic mutants at stage 14 and 15 in pooled bulk RNAseq, with over 200 embryos per group.