GSE137200
Pattern occupation of HDACs on chromatin determines PI3K/AKT inhibitor resistance in cancers [RNA-seq]
Blocking BRD4 or HDACs induces paradoxically similar gene expression, comparably attenuates PI3K/AKT inhibitor resistance in multiple cancer cells. Overall design: Examination of RNA expression in: GDC-0068 resistant PC-3 (PC-3-GDC-R) cells and control PC-3 (PC-3-control) cells.