PRJNA828172
Clec12a deficiency effects on the microbiota and macrophages
Clec12a is most highly expressed in myeloid lineages including macrophages. This study aims to understand the effect on the microbiota of Clec12a deficiency and how Clec12a deficient macrophages respond to a microbe found to be enriched in Clec12a-/- mouse intestines, which also exacerbates DSS-induced colitis.