GSE169721
Calcineurin inhibitor-induced renal side effects – Identification of underlying molecular mechanism via transcriptional analysis on large-scale isolated renal tubules
Comparing the transcriptional profiles of the CnB1-KO and control animals in order to to identify molecular pathways that are involved in the signal transduction of calcineurin in the DCT and explore the exact molecular pathogenesis of the CNI-induced renal side-effects. Overall design: Examination of the transcriptional profile of control and DCT-specific calcineurin knockout mice