PRJNA421205
Mouse PIWI proteins
In animals, PIWI-interacting RNAs (piRNAs) protect the germline and regulate gene expression. Two pathways make piRNAs. Endonucleolytic cleavage of primary transcripts generates phased precursor piRNAs (pre-piRNAs) that mature into primary piRNAs. In contrast, PIWI-catalyzed slicing initiates secondary piRNA production.