GSE183515
Biofilm Formation and Virulence of Shigella flexneri is Modulated by pH
In this study, we probed factors that could influence Shigella pathogenesis. We show that in basic pH conditions, deoxycholate-induced biofilm formation and virulence of Shigella are attenuated. We utilized RNA-sequencing to investigate pathways enriched in bacterial cells in biofilms. Overall design: Transcriptomic profiles of Shigella in different conditions of growth.