DRP008539
Investigation of the effects of sperm DNA methylation disturbance by testicular histone hyperacetylation on the next generation in mouse
The aim of the study was to investigate the epigenetic effects of hyperacetylation of testicular histones in mice on the next generation. This project includes sperm DNA methylation sequencing data from mice treated with VPA at 200 mg/kg/day for 6-10 weeks of age and control group mice at 12 weeks of age, DNA methylation sequencing data from morulas produced by in vitro fertilization using their sperm, and brain RNA-seq and sperm DNA methylation sequencing data from their mouse offspring.
The aim of the study was to investigate the epigenetic effects of hyperacetylation of testicular histones in mice on the next generation. This project includes sperm DNA methylation sequencing data from mice treated with VPA at 200 mg/kg/day for 6-10 weeks of age and control group mice at 12 weeks of age, DNA methylation sequencing data from morulas produced by in vitro fertilization using their sperm, and brain RNA-seq and sperm DNA methylation sequencing data from their mouse offspring.