GSE112298
Gene Expression Analysis of  metastatic CRPC cell line C4-2B treated with the dual BET-kinase inhibitor MA4-022-1
We identified BRD4 as an epigenetic regulator of  the prostate lineage specific gene HOXB13  during progression of the disease from an androgen dependent to an androgen independent state. Overall design: The design was to identify novel genes that are essential for CRPC growth and treaan be targeted with MA4--022-1