PRJNA725515
Quantifying chromosomal instability from intratumoral karyotype diversity
Despite the the likely prognostic significance of chromosomal instability in cancer, current measures of chromosomal instability are challenging to implement in patient tumors. The goal of this study is to characterize the diversity of single-cell karyotypes within a population of cells, including cells treated with paclitaxel to enable the development of new measures of chromosomal instability.