GSE130407
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas
Understand how Wnt5a depletion affects the growth of diffuse intrinsic pontine gliomas Overall design: SF7761 and SF8628 cells are H3.3K27M mutant diffuse intrinsic pontine glioma cells, SF9427 is glioblastomas with wild type histone H3. Every cell line was treated with None-target control shRNA, two shRNAs against Wnt5a