GSE202024
Early Developmental Deficits in the CF sheep model
Cystic Fibrosis (CF) is associated with pathology in multiple tissues including the lung, digestive tract and reproductive system. Lung disease is primarily a post-natal event but other organs are affected before birth. Here we use the CF sheep model to investigate the initiation and progression of CF disease through gestation. Overall design: RNA-seq of sheep (ovis aries) tracheal epithelial tissue