GSE158909
Oxidative stress alters transcript localization of disease-causing genes in the retinal pigment epithelium
To evaluate the effect of oxidative stress on transcript localization in the retinal pigment epithelium (RPE), we performed poly-A RNA sequencing on nuclear and cytoplasmic fractions from induced pluripotent stem cell-derived retinal pigment epithelium (iPSC-RPE) cells exposed to hydrogen peroxide, as well as untreated controls. Overall design: RNASeq analysis of nuclear and cytoplasmic fractions from control iPSRPE cells and iPSRPE cells subjected to hydrogen peroxide