GSE209602
Effect of endothelial ADAM10 deficiency on the aorta in an atherosclerosis mouse model
Mice lacking ADAM10 in endothelial cells (Tie2Cre driven) and flox-control mice were injected with an AAV8-PCSK9 virus and put on a Western-type diet for 10 weeks to induce atherosclerosis. Aorta's (Thoracoabdominal) were isolated (removal of PVAT) and processed for RNA-sequencing. Overall design: RNAseq of mouse Aorta