ena-STUDY-UNIVERSITY OF CAMBRIDGE-24-11-2020-22:48:50:198-686
Isolate genomes from the Mouse Microbial Genome Collection
Mouse models are essential for biomedical science and drug discovery, yet it is not known how the bacteria in the mouse microbiota – important determinants of phenotypes of health and disease – affect their relevance to human disease. To interrogate the taxonomic and functional differences between the human and mouse gut microbiotas, we developed the Mouse Microbial Genome Collection (MMGC), a compilation of 276 genomes from cultured isolates (under this study) and 45,768 metagenome-assembled genomes (MAGs) from 1,960 publicly available mouse metagenomes (under study PRJEB42344).
Mouse models are essential for biomedical science and drug discovery, yet it is not known how the bacteria in the mouse microbiota – important determinants of phenotypes of health and disease – affect their relevance to human disease. To interrogate the taxonomic and functional differences between the human and mouse gut microbiotas, we developed the Mouse Microbial Genome Collection (MMGC), a compilation of 276 genomes from cultured isolates (under this study) and 45,768 metagenome-assembled genomes (MAGs) from 1,960 publicly available mouse metagenomes (under study PRJEB42344).