PRJNA525437
Exome sequencing analysis of UM-SCC HNSCC cell lines
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer world wide, and survival rates range from 40-80% depending on subsite. As novel treatment strategies are investigated, comprehensively characterized cell lines representative of the diversity seen in patients will be crucial to correlating genetic and phenotypic features with therapeutic response. The University of Michigan has generated a large panel of HNSCC cell lines called UM-SCC that are utilized in laboratories worldwide. Here, we provide exome sequencing of subset of these cell lines to inform selection of model systems for future studies.