PRJNA484714
Transcriptome analysis of Edwardsiella piscicida EIB202 evrA mutant compared to wild type by RNA sequencing
Our analysis uncovered a novel GlpR family regulator EvrA is essential for activating T3/T6SS gene expression by binding directly to esrB promoter region and activates its expression in vivo of the host. Moreover, mannose facilitates EvrA-dependent esrB expression for in vivo virulence.