ena-STUDY-UNIMELB-19-09-2013-03:49:10:356-8
The genome of a European roe deer with an intersex phenotype, that was consistent with a XY genotype, encoded a triple dose of the SOX9 gene.
A complex network of genes determines sex in mammals. We studied a European roe deer with an intersex phenotype that was consistent with a XY genotype with incomplete male-determination. Whole genome sequencing and quantitative real-time PCR analysis revealed a triple dose of the SOX9 gene, allowing insights into a new genetic defect in a wild animal.
A complex network of genes determines sex in mammals. We studied a European roe deer with an intersex phenotype that was consistent with a XY genotype with incomplete male-determination. Whole genome sequencing and quantitative real-time PCR analysis revealed a triple dose of the SOX9 gene, allowing insights into a new genetic defect in a wild animal.