GSE126337
Musashi-1 is a master regulator of aberrant translation in Group 3 medulloblastoma
Transcripts regulated by Musashi-1 (MSI1) are explored through shRNA-mediated knockdown of MSI1 in SU_MB002 medulloblastoma cells. Overall design: SU_MB002, a treatment refractory pediatric medulloblastoma cell line is transduced with either a scrambled control or shMsi1 knockdown construct. The changes in transcriptomic profile is identified through RNA-sequencing