GSE134875
Transcriptome analysis of CD4+ T cells differentiated from wild-type and tumor bearing C57BL/6J mice
We report a crosstalk between T follicular helper (Tfh) and Th2 cells mediated by the Prostaglandin D2 (PGD2) and it's deletrious impact in cancer. Overall design: Examination of the expression profile of CD4+ T cells after 48h of in vitro differentiation and cell sorting from tumor bearing C57BL/6J mice.