GSE195487
The METTL14 component of the RNA methyltransferase complex influences estrogen signalling in MCF-7 breast cancer cells
siRNAs targeting METTL14 were used to deplete METTL14 in MCF-7 breast cancer cells and the effect on basal and estrogen regulated gene expression determined. Overall design: A pool of siRNAs were used to deplete METTL14 in MCF-7 breast cancer cells and the effect on basal and estrogen regulated gene expression and alternative splicing determined using RNA sequencing.