GSE134938
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells
Our study reveals that while antiestrogen therapies effectively limit tumor growth in ER-positive breast cancers, they also trigger a transcriptional program that favors immune evasion. Overall design: Study of differential gene expression among MCF-7 breast cancer cells cultured in DMEM, SFM (steroid free medium) or Fulvestrant