PRJNA681811
Safety and Modulatory Effects of Humanized GOS
Complex HMOs are uniquely abundant in human breast milk but not in that of other mammals and are composed of repeating and variably branched lactose and/or LacNAc units often attached to sialic acid and fucose monosaccharides. Human glycosyl-hydrolases do not degrade most HMOs, indicating that these structures have evolved as natural prebiotics to drive the proper assembly of a healthy gut microbiota during infancy.