GSE173438
ORC1 binds to cis-transcribed RNAs for efficient activation of human origins [ORC1_RIPseq]
By investigating the RNA binding activity of human ORC1, we show that it interacts with RNAs transcribed at active origins, which is linked to ORC1 dynamic association to the chromatin and optimal origin firing in S phase. Overall design: ORC1 native RIP-seq from nuclei of untreated HCT116 cells.