GSE160747
Establishing a molecular phenotype for Angelman Syndrome stem cell-derived neurons
mRNAseq on (1) isogenic control and Angelman Syndrome pluripotent stem cell-derived neurons or (2) antisense oligonucleotide-treated H9 hESC-derived neurons Overall design: Stranded mRNAseq was performed on six (6) replicates of 12-week isogenic iPSC-derived or hESC-derived neurons (Angelman Syndrome or control) and on six (6) replicates of 10-week UBE3A ASO or scramble ASO-treated H9 hESC-derived neurons