ena-STUDY-NETHERLANDS CANCER INSTITUTE-19-12-2017-09:28:18:184-49
RNAseq of mouse stromal compartment of melanoma PDX
Sequence data (RNA/DNA) of patient derived Xenografts (PDX)not only contains reads of human (tumor) origin but also of mouse (host) origin. We developed XenofilteR, a tool to computationally dissect human and mouse sequence reads from xenograft sequence data. One of the validation sets for the tool includes the RNAseq data of the mouse stromal compartment.
Sequence data (RNA/DNA) of patient derived Xenografts (PDX)not only contains reads of human (tumor) origin but also of mouse (host) origin. We developed XenofilteR, a tool to computationally dissect human and mouse sequence reads from xenograft sequence data. One of the validation sets for the tool includes the RNAseq data of the mouse stromal compartment.