GSE136003
Rbm24 functions as a critical translational regulator to pretect crystallin proteins accumulation for lens transparency. RNA-seq data of 33 hpf rbm24a-/- and wildtype embryo, head explant
This experiment is aimed to compare the transcriptomes of rbm24a mutant and wildtype at 33 hpf. As Rbm24a is an RNA binding protein, this comparation is suitable to obtain information on differential gene expression and alternative splicing. We found that the expression of most of the crystallin genes and many other lens specific genes are down regulated in rbm24a mutant, without changes in splicing patterns. Overall design: It contains two groups: wildtype and rbm24a-/-. Wildtype was used as control