GSE158949
Effects of spheroid and adherent growth conditions in ovarian cancer
Purpose: To understand the changes in RNA expression in tumor-initiating cell (TIC) (spheroid) and non-TIC populations (adherent) in ovarian cancer. Methods: OV90 cells were grown in adherent (non-TIC) or spheroid (TIC) conditions. Total RNA was extracted from each condition and RNAseq was performed and analysed for differential gene expression between the conditions. Overall design: Comparison of OV90 cells grown in adherent or spheroid conditions.