ena-STUDY-MRC LABORATORY OF MOLECULAR BIOLOGY-15-09-2020-23:36:53:897-8
Sequencing of haematopoietic stem and progenitor cell clones from Aldh2-/- Adh5-/- mice
Haematopoietic stem and progenitor cells from bone marrow of aged wild-type, Aldh2-/-, Adh5-/- and Aldh2-/- Adh5-/- mice were expanded clonally in vitro then subjected to whole-genome sequencing to identify the mutational imprint.
Haematopoietic stem and progenitor cells from bone marrow of aged wild-type, Aldh2-/-, Adh5-/- and Aldh2-/- Adh5-/- mice were expanded clonally in vitro then subjected to whole-genome sequencing to identify the mutational imprint.