GSE162515
Chromatin accessibility associates with protein-RNA correlation in human cancer
This work describes a previously unreported link between the chromatin states and protein abundance in cancer. We curated and studied a novel cohort of human thyroid tumors that allowed us to identify chromatin features that directly regulate protein expression. We believe this is the first study to establish chromatin states that reflect protein abundances in human cancer. Overall design: Examination of chromatin accessibility and gene expression in thyroid cancer