GSE114547
H3.3 phosphorylation promotes enhancer acetylation and lineage specification [ATAC-seq]
H3.3 phosphorylation promotes high levels of histone acetylation in mouse embryonic stem cells, which are central to the initiation of new transcription during lineage specification. Overall design: ATAC-seq analysis in mouse embryonic stem cell lines (WT and H3.3KO, and WT and HIRAKO). ATAC-seq analysis in embryoid bodies at D4 of differentiation (Control and H3.3KO).