GSE124083
Genomic instability in the naturally and prematurely aged myocardium [variants: data set 1]
Our data demonstrate that genomic instability does not evidently contribute to naturally aging of the mouse heart and support the contention that the endogenous DNA repair machinery is remarkably active to maintain genomic integrity in cardiac cells throughout life. Overall design: Investigation of genetic variants in natural aging and accelerated aging mouse model Ercc1.