GSE126618
Whsc1 controls mesendodermal transcription factor expression
We report here chromatin related factor Whsc1 links pluripotency exit and mesendodermal differentiation. We performed RNA-seqs to compare Whsc1+/+ and Whsc1-/- embryonic stem cells (ESCs)  to compare the transcriptomes. UMI-4C experiments have been performed to identify regions having contacts with promoter regions of downstream Whsc1 targets: the mesendoderm transcritpion factors Overall design: RNA-seq in Whsc1+/+ and Whsc1-/-  ESCs. UMI-4C in Whsc1+/+ and Whsc1-/- ESCs compared to D6 Whsc1+/+ and Whsc1-/- embryoid bodies (Ebs).