GSE160454
Transcriptome analysis in DNMT3A and 3B mutant female human pluriopotent stem cells.
We report that the effect of deletion of de novo DNA methyltransferases on transcriptome status in female human ES cell and iPS cell by bulk RNA-sequencing. Overall design: Examination of gene expression levels in female human ES cell and iPS cell. Definitions: "Eroded" means the cells showing erosion of dosage compensation of X-chromosome inactivation. "Non-eroded" means that the cells that retain normal X-chromosome inactivation (i.e. the cells does not show erosion of dosage compensation of X-chromosome inactivation).