GSE112363
Next Generation Sequencing Facilitates Quantitative Analysis of FZD2 Knockdown/Control SNU449 Cell Line Transcriptomes
We report evidence that FZD2 is a driver for EMT, cancer stem cell (CSC) property, and vasculogenic mimicry (VM) in hepatocellular carcinoma. To further examine the transcriptional changes in response to FZD2 depletion, we performed RNA-seq with FZD2 knockdown and control SNU449 cells by BGISEQ-500. Overall design: mRNA profiles of FZD2 knockdown and control SNU499 cells were generated by deep sequencing, using BGISEQ-500.