GSE195532
The METTL3 RNA methyltransferase regulates estrogen signalling in MCF-7 breast cancer cells
siRNAs targeting METTL3 were used to deplete METTL3 in MCF-7 breast cancer cells and the effect on basal and estrogen regulated gene expression determined. Overall design: A pool of siRNAs were used to deplete METTL3 in MCF-7 breast cancer cells and the effect on basal and estrogen regulated gene expression and alternative splicing determined using RNA sequencing.