GSE109722
Marfan syndrome in mice
Comparison of whole genome expression profiles to characterize gene expression during development of thoracic aortic aneurysm in fibrillin-1 hypomorphic mice (Fbn1mgR/mgR). Overall design: We compared biological processes identified from transcriptomic analyses of aortic tissue harvested from Fbn1mgR/mgR mice, a validated model of early onset, progressive, severe Marfan syndrome (MFS).