GSE160076
Examining Sex Differences in the Human Placental Transcriptome During the First Fetal Androgen Peak
Sex differences in human placenta exist from early pregnancy to term. However, it is unclear whether these differences are driven solely by sex chromosome complement or are subject to differential sex hormonal regulation. Here, we survey the human chorionic villus (CV) transcriptome for sex-linked signatures from 11 to 16 gestational weeks, corresponding to the first window of increasing testis-derived androgen production in male fetuses.  Overall design: 12 male and 11 female chorionic villus biopsies