GSE99888
Single-cell transcriptomic analysis of mouse CA1 inhibitory neurons
We  studied  the  transcriptomes of mouse CA1 inhibitory cells. Novel clustering methods identified all 23 previously  described  CA1  inhibitory  types,  while  also  suggesting  6  new  inhibitory  classes.  Latent-factor  analysis revealed a common continuum of expression of many genes within and between classes,  which  we  hypothesized  correlates  with  a  continuum  from  faster-spiking  cells  that  proximally  target pyramidal cells, to slower active cells targeting pyramidal distal dendrites or interneurons. Overall design: 6971 single cells isolated from the mouse cortex CA1 region