GSE134522
EMP2 functions as a novel target for breast cancer stem cells
Little is know about the role of epithelial membrane protein-2 in breast cancer development or progression.  In this study, we tested the hypothesis that EMP2 may regulate the formation or self-renewal of breast cancer stem cells (BCSC) in the tumor microenvironment. Overall design: Stable SUM149 cells were created that express a vector control or shRNA lentiviral construct.  Differential expression analysis was performed on these cell lines.