GSE75312
Affymetrix SNP array data for samples of 9 members of a FNMTC family
Familial nonmedullary thyroid cancer (FNMTC) is a disease with the inheritance pattern is autosomal dominant with incomplete penetrance, but the causative gene is not clear. To identify the disease related locus in the FNMTC family, whole-genome SNPs of nine family members (five affected and four unaffected) were genotyped. We analyzed the SNP data with a novel method and mapped the disease-causing gene to several regions on the whole genome. Overall design: Affymetrix SNP arrays were performed according to the manufacturer''s directions on DNA extracted from peripheral blood samples.