GSE160807
Hippocampal transcriptome analysis of glucocorticoid enhanced memory formation [RNA-seq]
Aim: We investigated whether glucocorticoid effects on memory are associated with genomic interactions between the GR and pCREB in the hippocampus. Methods: Adult male rats received 3 minutes of object exploration training or no training either with a 3.0mg.kg post-training corticosterone or vehicle injection to study the molecular effects underlying enhanced memory formation. Hippocampi were dissected 3 hours after injection and snap-frozen. Subsequently, total RNA was isolated and send for 100bp paired-end sequencing by BGI. Overall design: Hippocampal mRNA profiles of male rats studying glucocorticoid enhanced memory formation.