PRJNA787952
Raw_metagenomic_sequencing_for_Pediatrics_Gut_Decontamination_NCT02641236
A Randomized Phase 2 Study to examine the impact of gut decontamination (GD) with oral vancomycin-polymyxin B on the intestinal microbiome composition in pediatric patients undergoing allogeneic hematopoietic cell transplant (allo-HCT). Exploratory aims look at clinical outcomes including acute graft-versus-host disease (aGVHD) and the risk of bloodstream infections (BSI).