Recon_Project__Genetic_reconnaissance_technology_to_support_malaria_elimination_in_the_Greater_Mekong_Subregion__GMS_-sc-4590
Recon_Project__Genetic_reconnaissance_technology_to_support_malaria_elimination_in_the_Greater_Mekong_Subregion__GMS_
The ongoing emergence of slow-clearing parasite strains in the GMS is considered the single greatest threat to to the use of artemisinin combination therapies (ACT) to control malaria. The spread of artemisinin resistance to African parasites could roll back recent achievements, with disastrous effects – and thus major efforts are underway to eliminate Plasmodium falciparum malaria from the GMS. It is hoped that this work will benefit endemic regions across the world by helping to preserve the effectiveness of artemisinin, and by developing a technological platform deployable in other control and elimination contexts (in the Americas and in Africa).
Providing technologies and information systems for the extraction of genetic information from malaria Plasmodium parasites in field blood samples collected across the Greater Mekong Subregion (GMS), and applying state-of-the-art analytic tools to derive knowledge that will inform intervention decision-makers in the countries and support malaria elimination projects.