GSE136844
LINE-1 promoter methylation analysis in brain development
We performed methylation analisys of L1MdTf sequence and IAPLTR1a during mouse brain development, in cortex, hippocampus and cerebellum at different developmental stages (E15.5, E18.5, P0, P3, P14). We defined specific waves of methylation for L1MdTf promoter. Overall design: Bisulfite conversion based methylation analysis of L1MdTf and IAPLTR1a elements during mouse brain development. We analyzed cerebellum, cortex and hippocampus at 5 different developmental stages E15.5, E18.5, P0, P3 and P14. 4 mice at each developmental stage were analyzed.