GSE125930
Transcriptional profile of LPS-stimulated murine macrophages treated with bacterially derived fatty acid
We used RNA-seq to profile the effect of a bacterially derived fatty on LPS-stimulated murine macrophages. From the transcriptional response, there was a significant decrease of inflammatory signals with lipid treatment, and pathway analysis of differentially expressed genes suggests PPAR alpha as potential anti-inflammatory mechanism. Overall design: examination of anti-inflammatory effects of 10(Z)-hexadecenoic acid on LPS-stimulated murine peritoneal macrophages