PRJNA171163
Single Neuron Sequencing Quantifies L1 Retrotransposition and Somatic Mutation in the Human Brain
300 single neurons, and additional bulk DNA samples, were sequenced from 3 neurologically normal individuals to measure somatic LINE-1 (L1Hs) insertion rates. An additional 8 single neurons, and bulk DNA samples, were sequenced at low-coverage to characterize whole genome amplification coverage.