GSE134088
Next Generation Sequencing Facilitates Quantitative Analysis of the control and H2O2-treated IMR90 cells Transcriptomes
We generated 6 Gb of high-quality sequencing data (per sample) and catalogued the expression profiles of annotated genes in each sample. The analysis showed differences of transcriptomes between the control and H2O2 treatment as well as revealed that H2O2 treatment induced genes expression changes. We identified numerous differentially expressed genes that known or potential roles in cellular senescence.Therefore, they are appealing candidates for further investigation of the gene expression and associated regulatory mechanisms related to cellular senescence Overall design: IMR90 cells mRNA profiles of the control and H2O2 treatment were generated by deep sequencing, in triplicate, using Illumina HiSeq2000.