GSE121663
Role of iron in the regulation of the epithelial-to-mesenchymal transition (RNA-seq)
The biological process termed Epithelial-to-Mesenchymal Transition (EMT) plays a central role in cancer cell invasion, metastasis, self-renewal and resistance to therapy1,2. Here, we characterize using RNA sequencing  the mRNA levels changes occurring during EMT induced by epidermal growth factor in breast cancer MDA-MB-468 cells.  1. Nieto, M. A., Huang, R. Y., Jackson, R. A. & Thiery, J. P. EMT: 2016. Cell 166, 21–45 (2016). 2. Puisieux, A. & Brabletz, T. & Caramel, J. Oncogenic roles of EMT-inducing transcription factors. Nat. Cell Biol. 16, 488–494 (2014). Overall design: Analyses of 6 samples: (i) untreated (ii) EGF 72h. Experiment was performed in 3 independent biological replicates