GSE98473
Androgen receptor agonists increase muscle mass and function in preclinical models of DMD
Mdx mice were castrated and treated with selective androgen receptor modulator (SARM) GTx-026. Ten weeks after treatment, gastrocnemious muscle were isolated, RNA extracted, and sequenced using ion torrent sequencer. Overall design: n=3/group. Group-1 wildtype mice, group-2 mdx mice treated with vehicle, and group-3 mdx mice treated with 10 mg/kg s.c. GTx-026