GSE125588
Single Cell RNA seq of Genetically Engineered Mouse Models of Pancreatic Adenocarcinoma
We report the scRNAseq profiles of three mouse models of pancreatic cancer: KIC, KPfC, KPC.  Analyses demonstrate the existence of 2 molecular subtypes of cancer cells, 2 molecular subtypes of cancer associated fibroblasts, and 2 molecular subtypes of cancer associated macrophages. Overall design: Untreated mice were sacrificed at various time points prior to scRNA library generation: normal mouse at 60 days, early KIC mouse at 40 days, late KIC mouse at 60 days, late KPfC mouse at 60 days and KPC mouse at 6 months.