GSE184183
Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers (PROseq)
Determine the direct effects of chromatin remodeler on transcription using inducible protein degradation combined with nascent transcriptomics. Overall design: Nascent RNA transcription measured by PRO-seq upon AID-mediated depletion of chromatin remodelers. All cell lines have OsTir1 expression from the Act5c locus, and AID tagged gene indicated in genotype. All experiments were performed in 2 biological replicates.