GSE201370
IDENTIFICATION AND FUNCTIONAL DEMONSTRATION OF A FETAL-SPECIFIC AXIS THAT POTENTLY SUPPRESSES MLL-FUSION DRIVEN MURINE AML RNA-seq [L28BME vs ME]
LIN28B suppresses MLL-ENL driven AML. The tumor suppressor effects of LIN28B are largely driven by positive regulation of MYBBP1A. Overall design: RNA-seq was performed on GMLPs (Lin- Kit+ SCa1+ CD48+ CD150-) from ME or L28BME mice (3 replicates per group).