GSE176475
Identification of differential expressed genes after HHEX/YAP/TAZ/TEAD knockdwon in colorectal cancer cells
We have identified HHEX as an oncogene to promote proliferation in colorectal cancer. To elucidate the potential mechanism of HHEX in colorectal cancer, RNA-seq analysis was performed in HCT116 cells to analyze differential expressed genes after HHEX knockdown. Overall design: HCT116 cells transiently expressing siNC control, siHHEX_1, siHHEX_2, siHHEX_3, siYAP/TAZ_1, siYAP/TAZ_2 or siTEAD1/2/3/4.