b33592a4-ec7e-42da-889b-2d5f1c1ceabf
Variant analysis of patient-derived xenografts in NSG mice
Human patient-derived xenograft models were generated using subcutaneous tumor implantation in female NOD.Cg-Prkdc Il2rg/SzJ (NSG; JAX strain 005557) host mice. Tumors were grown, collected, and fragmented for serial passage in NSG mice. Tumor samples at described passage numbers were taken for variant analysis.
Human patient-derived xenograft models were generated using subcutaneous tumor implantation in female NOD.Cg-Prkdc Il2rg/SzJ (NSG; JAX strain 005557) host mice. Tumors were grown, collected, and fragmented for serial passage in NSG mice. Tumor samples at described passage numbers were taken for variant analysis.