PRJNA512113
The LilBUBome
LilBub is an unusually small cat with some traits that resemble known developmental disorders. She has extra digits on every paw, no teeth and a short snout, which is why her tongue hangs out. Also, her skeleton produces too much bone tissue, a rare disease known as osteopetrosis.While LilBubs combination of traits is unique, we know humans, cats, dogs and mice that have certain subsets of these features. We therefore think LilBub's looks could be caused by mutations in her DNA that resemble those found in patients and other animals. By sequencing and analyzing the whole genome of LilBub we want to identify this mutation.