GSE183251
ASBT inhibition alleviates cholangiopathy and hepatic fibrosis development in Cyp2c70-/- mice
RNA-seq was used to compare the liver gene differentiation between WT and Cyp2c70-/- mice fed with chow and SC-435 containing diet. We aimed to characterize the cholestatic liver phenotype in the Cyp2c70 -/- mouse and test whether ASBT inhibition reduced injury. Overall design: Examine liver gene expression between WT and Cyp2c70-/- mice fed with chow and SC-435 containing diet.