GSE136073
Exome mutations in mouse LMP1 Lymphomas
10 LMP1 expressing mouse lymphomas were sorted and sequenced for exome mutations Overall design: 10 Rag2KOcgKO were reconstituted with  fetal liver hematopoietic stem and progenitor cells (HSPC) from Cd3eKO Cd19-Cre R26LMP1stopf mice. Developing LMP1-driven B-cell lymphomas were transplanted in secondary  Rag2KOcgKO or  Rag2KO mice. Secondary lymphomas were FACSpurified (CD19+huCD2+). gDNA of sorted lymphoma samples was analyzed by exmoe sequencing