GSE159991
Bulk RNAseq of AML and endothelial cells in untreated and cytokine-treated conditions
We report the use of bulk RNAseq of AML and endothelial cell lines in four conditions (1. Untreated; 2. IFNg - 10 ng/ml; 3. TNFa - 10 ng/ml; 4. IFNg and TNFa - 10 ng/ml) in order to identify genes that are differentially expressed between the two cell types, both at baseline and in an inflammatory microenvironment. Overall design: mRNA profiles of AML and endothelial cells at baseline and after 24h exposure to proinflammatory cytokines IFNg and/or TNFa