PRJNA862633
RNA sequencing of wild-type and UCKL1 knockdown RKO cell lines
Uridine-Cytidine Kinase-Like 1 (UCKL1) is an enzyme involved in the pyrimidine nucleoside salvage pathway. It is highly upregulated in colorectal cancer (CRC). Down-regulation of UCKL1 led to reduced CRC cells growth and migration. However ,regulatory mechanisms of UCKL1 in CRC are yet to be fully understood. To further explore the functions and mechanisms of UCKL1 in CRC, we performed RNA Sequencing assay to compare the transcriptome of the wild-type and UCKL1 knockdown RKO cells.