GSE129756
Next Generation Sequencing of TMAO (Trimethylamine N-oxide)-treated Cardiac Transcriptomes
To investigate the mechanism how TMAO deteriorates cardiac dysfunction in murine left ventricular pressure overload model, we performed RNA-seq analysis with cardiac tissue from TMAO-treated mice. Overall design: Cardiac mRNA profiles of 13-weeks old wild type mice treated with TMAO for 2 weeks were generated by RNA-seq using Illumina NextSeq500.