GSE202522
Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2
The cytoskeletal mechanisms regulating inflammatory responses in the epidermis are not well described. Here we addressed this question by inducing a psoriatic phenotype in human keratinocytes and reconstructed human epidermis using a cytokine stimulation model.We report the results from RNA-seq  in N/TERT keratinocytes treated with M5 or both M5 and ROCK2 inhibitor KD025. Overall design: N/TERT keratinocytes treated 24h with M5 or both M5 and ROCK2 inhibitor KD025.