GSE174117
The diarrheal pathogen Cryptosporidium parvum exports proteins into the cytoplasm of the infected host cell
We found members of the polymorphic C. parvum MEDLE protein family to be targeted into the cytoplasm of infected cells. Direct expression of MEDLE2 in mammalian cells triggers an ER stress response that is also observed during infection. Overall design: Three biological replicates were analyzed for each of 4 conditions (transfected or untransfected based on green fluorescence assessed by flow cytometry  from the MEDLE2-GFP or GFP control)