PRJNA795692
Histone chaperone NRP1 mutations affect genome transcription in Tetrahymena
Nrp1TrNLS1 overexpression severely affects the acetylation level of H3K56. Decreased acetylation of H3K56 could contribute to enhancements in the transcription barrier. RNA-seq analysis showed that 794 DEGs are downregulated whereas 540 DEGs are upregulated in the Nrp1TrNLS1 mutant