E-MTAB-5962
RNA-Seq of RAW 264.7 cells stimulated with the AS03 adjuvant after 4 and 8 hours
The Adjuvant System 03 (AS03) containing is an oil-in-water emulsion containing a-tocopherol and squalene that is used in several licensed vaccines.  However, the molecular mechanisms involved in its immunostimulatory properties are ill-defined.  Here, we have investigated the response of myeloid RAW 264.7 cells to stimulation with AS03 in vitro.
The Adjuvant System 03 (AS03) containing is an oil-in-water emulsion containing a-tocopherol and squalene that is used in several licensed vaccines.  However, the molecular mechanisms involved in its immunostimulatory properties are ill-defined.  Here, we have investigated the response of myeloid RAW 264.7 cells to stimulation with AS03 in vitro.