GSE110360
Jmjd3 is required for tissue-restricted antigens expression in mTECs
To understand the role of Jmjd3 in medullary thymic epithelial cells (mTECs) function and development, Jmjd3 was conditionally deleted in thymic epithelial cells. At the age of 4 weeks, mTECs were sorted by flow cytometry and RNA-seq was performed to identify the genes targeted by Jmjd3 for repression. Overall design: RNAseq on control or Jmjd3-deficient murine medullary thymic epithelial cells.