Evaluating_new_methods_and_difficult_samples_for_insights_into_Anopheles_population_structure-sc-4287
Evaluating_new_methods_and_difficult_samples_for_insights_into_Anopheles_population_structure
Short read sequencing of Anopheles samples do not easily assemble. In this study, we are testing the 10x chemistry to assess whether larger scaffolds are possible, and whether haplotypes are resolved. We are also exploring standard sequencing of highly degraded samples to determine the quality of the genomes we can produce from difficult samples. Samples will have DNA extractions done in different ways, and some will be subjected to whole genome amplification. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
The aim of the project is to develop new methods that enable better genomes and access to difficult samples in order to gain greater insight into Anopheles population structure.