GSE168099
RNAseq in BRD4 reporter KBM7 cells (REDS1 and REDS15) with purine metabolism perturbation
To investigate the transcriptional profile in two BRD4 reporter clones (REDS1 and REDS15) with purine metabolism perturbation Overall design: 3'mRNA sequencing in REDS1 and RED15 clones with DMSO, 10 µM 6-mercaptopurine or 1 µM (+)-JQ1 treatment for 72 hours and with sgRen or SLC35F5/29A4/28A3 knockout 12 days post sgRNA delivery