ena-STUDY-Orebro University Hospital-06-11-2018-13:10:37:505-950
Multidrug-resistant Neisseria gonorrhoeae isolate from Ireland, 2018
We describe a multidrug-resistant Neisseria gonorrhoeae urethritis with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Ireland, August 2018. Whole-genome sequencing showed that the isolate IR72 was belonging to the internationally spreading multidrug-resistant ceftriaxone-resistant FC428 clade, initially described in Japan in 2015. IR72 was assigned MSLT ST1903, NG-MAST ST17842 and NG-STAR type 1133, including the ceftriaxone resistance-mediating penA-60.001. Enhanced awareness of internationally spreading ceftriaxone-resistant gonococcal strains threatening recommended dual therapies are essential.
We describe a multidrug-resistant Neisseria gonorrhoeae urethritis with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Ireland, August 2018. Whole-genome sequencing showed that the isolate IR72 was belonging to the internationally spreading multidrug-resistant ceftriaxone-resistant FC428 clade, initially described in Japan in 2015. IR72 was assigned MSLT ST1903, NG-MAST ST17842 and NG-STAR type 1133, including the ceftriaxone resistance-mediating penA-60.001. Enhanced awareness of internationally spreading ceftriaxone-resistant gonococcal strains threatening recommended dual therapies are essential.