GSE211868
Wnt-Activating Human Skin Organoid Model of Atopic Dermatitis Induced by Staphylococcus aureus and Its Protective Effects by Cutibacterium acnes
We investigated transcriptional changes associated with S. aureus infection by performing RNA sequencing. the goal of this transcriptome analysis was to confirm ALI-skin organoids can capture the host cellular responses against bacterial infection including bacterial recognition and inflammatory signaling. Overall design: The total RNA was extracted from three biological replicates of ALI-skin organoids after treatment with S. aureus (106 CFU) for 18 hrs