PRJNA757943
p-STAT3 (Tyr705) Chip-seq
The hypoxia induced neuron apoptosis resulting in cognitive dysfunction, is associated with Inflammatory factors, such as IL6. IL6 binds to its receptor thereby activating Janus kinase, which in turn activates signal transducer and acdtivator of transcription 3 by tyrosine 705 phosphorylation. However, the downstream mechanism of STAT3 in neuron death is not yet clear. Here, determined the pSTAT3(Tyr705) was by the ChIPseq.