GSE127004
SETD5 is a H3K36 methyltransferase which preserves transcriptional fidelity during brain development and neuronal wiring [RNA-seq]
We assess the role of Setd5 on trancription elongation, by profiling nascent chromatin bound RNAs after DRB treatment an release, in wild type and Setd5 heterozygous mouse neural stem cells (NSCs). Overall design: Chromatin-bound RNA sequencing in DRB treated and at 5, 10 and 20 minutes after DRB release in wild type and Setd5+/- NSCs.