GSE138251
Biliary-Atresia-associated Mannosidase-1-alpha-2 gene regulates biliary and ciliary morphogenesis and laterality (zebrafish)
The effect of MAN1A2 on biliary morphogenesis, left-right patterning, and ciliogenesis was evaluated with knockdown in zebrafish and subsequent RNAseq experiment/analysis. Overall design: Total RNA sequencing protocol was performed on pooled liver tissue from all three batches, one from controls and one from man1a2 morphant zebrafish. Each pool consisted of 100 livers from three batches of zebrafish larvae at 5 days post fertilization.