PRJNA767195
MSL and BL1 human TNBC cell lines were evaluated by RNA sequencing
MSL and BL1 human TNBC cell lines were evaluated by RNA sequencing in the presence or absence of docetaxel, a frontline agent for TNBC patients. Functional and mechanistic assays were performed to evaluate the chemo-resistant pathway utilized by MSL TNBCs. Efficacy of targeted therapy against a docetaxel-induced inflammatory mediator in MSL TNBCs was performed with both cell line and patient derived xenografts in female NOD scid gamma (NSG) mice.