GSE125222
Novel mutations segregating with Complete Androgen Insensitivity Syndrome and their molecular characteristics.
We analysed three interesting, rare cases of CAIS (Complete Androgen Insensitivity Syndrome) and report three hitherto undisclosed causes of the disease. Comparative RNA-Seq analysis of CAIS and control samples (3 testicular oligobiopsies from men with normal spermatogenesis) revealed 4,293 significantly deregulated genes. Overall design: The comparative analysis of gene expression profiles by RNA-Seq between individuals with CAIS (n=3) and control (men with normal spermatogenesis) (n=3)