GSE124892
The transcription factor ERG regulates super-enhancers in endothelial cells [ERG siRNA]
We provide the functional and epigenomic evidence for ERG binding to super-enhancers in HUVEC and further show that loss of ERG results in inhibition of specific endothelial super-enhancers and associated target genes. Overall design: ChIP-seq was used to determine the changes to acetylated H3K27 and the transcriptional coactivator MED1 in response to ERG siRNA.