GSE112245
Joint single-cell chromatin and protein profiling reveals environmental regulation of epigenomic heterogeneity [Tumor_stained_for_EpCam_CD45]
A novel scATAC-seq approach, Multi-Index single cell ATAC-seq (MI-ATAC), in which we not only index the accessible chromatin of individual cells, but also index their protein expression using index Fluorescence Activated Cell Sorting (FACS). Overall design: Freshly isolated cells from a breast tumor were fixed, permeabilized and stained against EpCam and CD45,  then sorted into single wells of a 96 well plate for MI-ATAC