GSE184140
Oct4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 lysine methylation to pluripotency
We report RNA-seq expression data of different cell lines of mouse embryonic stem cells in self-renewal conditions and upon the inactivation of Oct4 or Esrrb. ChIP-seq of H3K9me3 and ATAC-seq data of wild-type and Suv39h1as deleted cells are also provided. Overall design: Parallel cultures of 2 replicates with or without TF depletion (24h, for RNA-seq) or of wild-type and Suv39h1-as mutant cells for ChIP-seq and ATAC-seq A8 and D8 are independent mutant clones.