GSE208362
Streptococcus pneumoniae drives specific and long-lasting memory in NK cells
Following lung infection with S. pneumoniae, naive (D21PBSpi NKs) and pre-infected NK cells (D21SPNpi NKs) were sorted and used for scRNAseq. We compared their transcriptional program to identify and characterize a new population of NK cells that acquired memory to  bacteria Overall design: Comparison of naive (D21PBSpi NKs) and memory NK cells (D21SPNpi NKs) mRNA profiles upon secondary S. pneumoniae infection