GSE160824
Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets
Adult female and aged male ferrets were inefcted with SARS-CoV-2. Nasal turbinates, the right cranial lung, and right caudal lung were collected on Day 2, 7, 14, and 21 after infection. Tissues were collected from uninfected animals as control. RNA was isolated and used for analysis of the transcriptome to determine any effects on gene regulation during SARS-CoV-2 infection from age or sex. Overall design: Adult female and aged male ferrets were infected with SARS-CoV-2 and tissues collected on Day 2, 7, 14, and 21 post infection. Uninfected ferret tissues were used as control.