GSE131535
A TCF-1-centered transcriptional network drives an early binary effector versus exhausted CD8+ T cell fate decision
We processed single cell RNA-Sequencing using 10X Genomics platform to study the population dynamics of LCMV antigen specific CD8+ T cells during early phase of acute and chronic infection. Overall design: P14 cells of Naïve, D8 p.i. ofLCMV- Armstrong, LCMV-Clone13 and LCMV-Clone13+GK1.5(?CD4) Cell barcodes ending in -1 are Naive,-2 are D8Arm,-3 are D8Cl13 and -4 are D8Cl13_aCD4 in the barcodes file supplied.