GSE162473
Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition
CRISPR knockout screening on MOLM-13 cells with KPT-9274 Overall design: MOLM-13 cells were transduced with geckov2 CRISPR knockout library (Addgene 1000000048   ) with: 1) baseline (7 days post library infection), 2) KPT-9274-treated, 3) DMSO control.