PRJNA525958
Homo sapiens Genome sequencing
Adenosine deaminase acting on RNA (ADAR1) is an important interferon-stimulating protein in the interferon alpha (IFNa) signaling pathway. Our previous studies have shown that ADAR1 polymorphisms affect response to IFNa therapy for chronic hepatitis B (CHB). The present study aimed to investigate the role of ADAR1 in promoting hepatitis B virus (HBV) replication.