GSE167477
MYCN directly regulates TET1 expression to control 5-hmC distribution and enhance neuroblastoma cell migration in hypoxia [ChIP-Seq]
We performed HIF-1alpha ChIP-seq in SK-N-BE(2) cells cultured in normoxia vs. hypoxia for 48 hrs. We identified two new HIF-1alpha binding sites in TET1 that control TET1expression in hypoxia Overall design: SK-N-BE(2) cells were cultured in normoxia or hypoxia for 48 hours. HIF-1alpha ChIP were performed on fixed chromatin