PRJNA682842
Long Non-Coding RNAs  Profiles in Cerebellum of  Niemann-Pick C1 Disease Mouse Model
Niemann-Pick type C disease (NP-C) is a neurodegenerative lysosomal storage disorder primarily caused by mutations in NPC1. However, its pathogenesis remains poorly understood. While mounting evidence demonstrate that long non-coding RNAs (lncRNAs) are implicated in the pathogenesis of neurodegenerative disorders, lncRNA expression in NP-C has not been profiled.