GSE125528
Genome-wide maps of chromatin state in renal tubular epithelial cells
To further understand the underlying mechanisms and identify genes directly regulated by SETD2 and H3K36me3 on a genome-wide scale, we performed chromatin immunoprecipitation using a H3K36me3 specific antibody followed by next-generation sequencing (ChIP-seq) assays using the renal tubules isolated from SETD2FL/FL KSPCRE/+ and its control SETD2fl/fl mice. Overall design: Examination of 2 different histione modifaication in 2 primary renal tubular epithelial cells