ena-STUDY-SRM UNIVERSITY-16-02-2018-05:42:17:520-357
Exploration of bioactive peptides from innate immune molecules of Channa striatus
Channa striatus is a freshwater fish with medicinal and nutritive values. It is one of the well-known disease resistant species, with well-developed innate immune system and primitive adaptive immune system. The innate immune molecules in fish are highly active since they act as bridge between invertebrates and vertebrates. Also they get continuous exposure to wide range of pathogens, hence their innate immune molecules are evolutionary important molecules and they serve as template for various pharmaceuticals specifically bioactive peptides. In this study, the immune genes with putative roles in innate immunity are identified from the transcriptome of Channa striatus and the proteins encoded by those genes are subjected for various analysis to identify the bioactive peptides.
Channa striatus is a freshwater fish with medicinal and nutritive values. It is one of the well-known disease resistant species, with well-developed innate immune system and primitive adaptive immune system. The innate immune molecules in fish are highly active since they act as bridge between invertebrates and vertebrates. Also they get continuous exposure to wide range of pathogens, hence their innate immune molecules are evolutionary important molecules and they serve as template for various pharmaceuticals specifically bioactive peptides. In this study, the immune genes with putative roles in innate immunity are identified from the transcriptome of Channa striatus and the proteins encoded by those genes are subjected for various analysis to identify the bioactive peptides.