PRJNA476063
USP7 Promotes DNA Methylation Homeostasis by Attenuating UHRF1- and Histone Ubiquitination-Dependent DNMT1 Recruitment
To better characterize the effects of USP7 on DNA methylation, we performed reduced representative bisulfite sequencing (RRBS) analysis for a genome-wide comparison of DNA methylation in wild-type, USP7-KO-1, DNMT3A/3B-DKO and DNMT3A/DNMT3B/USP7-TKO HeLa cell lines.