GSE161541
Genomic occupancy of MYC and members of the PRC1.6 complex (MGA, E2F6, MAX, L3MBTL2) in MGA WT (Empty) and MGA depleted (sgMga) KrasG12D Trp53 -/- mouse lung cancer lines
Conventional crosslinked ChIP was performed on cell lines derived from control (Empty) and sgMga transduced tumors. We wanted to assess PRC1.6 member and MYC binding in the presence and absence of MGA. Overall design: Conventional X-ChIP was performed on Empty and sgMga KP mouse lung cancer lines. Antibodies used: IgG control rabbit, IgG control mouse, anti-MAX, anti-MYC, anti-MGA, anti-L3MBTL2, anti-E2F6)