ena-STUDY-UCLA-02-10-2013-20:43:11:878-258
Analysis of the canine brain transcriptome with an emphasis on the hypothalamus and cerebral cortex
The diversity of dog breeds make the domestic dog a valuable model for identifying genes responsible for many phenotypic and behavioral traits.  The brain in particular, is a region of interest for the analysis of molecular changes that are involved in dog-specific behavioral phenotypes.  However, such studies are handicapped due to incomplete annotation of the dog genome.  We present a high coverage transcriptome of the dog brain using RNA-Seq.  Two areas of the brain, hypothalamus and cerebral cortex, were selected for their roles in cognition, emotion and neuroendocrine functions.
The diversity of dog breeds make the domestic dog a valuable model for identifying genes responsible for many phenotypic and behavioral traits.  The brain in particular, is a region of interest for the analysis of molecular changes that are involved in dog-specific behavioral phenotypes.  However, such studies are handicapped due to incomplete annotation of the dog genome.  We present a high coverage transcriptome of the dog brain using RNA-Seq.  Two areas of the brain, hypothalamus and cerebral cortex, were selected for their roles in cognition, emotion and neuroendocrine functions.