PRJNA727068
RNA seq of iRECs and Xenopus animal caps
To investigate the changes due to the R295C mutation in HNF1B, direct reprogramming in mouse embryonic fibroblasts (MEFs) and renal tissue induction in Xenopus animal caps (AC) were conducted using both wild type (WT) and R295C HNF1B (Mut). Differences between orginal tissue (MEFs/AC) , WT and Mut conditions were captured on transcriptome level in both species.