GSE211215
Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis
To investigate the function of AKR1B10 in the lung cancer brain metastasis cells, we established PC9-BrM3 cells in which AKR1B10 has been knocked down by shRNA. Overall design: We then performed gene expression profiling analysis using data obtained from RNA-seq of  PC9-BrM3 cells with or without AKR1B10 knockdown.