GSE122875
Transcriptional profile of stemness in the ovarian surface epithelium
We leverage RNA sequencing to identify the transcriptional changes assocaited with several experimental conditions that induce a stemness phenotype in the ovarian surface epithelium, including spheroid culture, Snail overexpression, and BRCA1 deletion Overall design: RNA sequencing of mOSE cultured as monolayers or spheroids (+/- TGFB1), and monolayer cells overexpressing Snail, or following deletion of BRCA1 (n=3 for each experiment)