E-MTAB-11163
Comparative transcriptome analysis of the three different stages of the regenerating zebrafish telencephalon
Adult zebrafish can completely regenerate a wide range of injured organs including the CNS. RNA sequencing (RNA-Seq) is a high-throughput sequencing method facilitating quantification of gene expression in a precisely manner. Development of RNA-Seq technologies and their extensive data-analysis methods make investigation of regulatory genes and functional gene annotations possible under specific conditions. In this study, we reveal the whole transcriptome profiles of the lesioned hemispheres of the zebrafish telencephalon at early wound healing (1 day post-lesion), early proliferative (3 day post-lesion) and differentiation (14 day post-lesion) stages of regeneration.
Adult zebrafish can completely regenerate a wide range of injured organs including the CNS. RNA sequencing (RNA-Seq) is a high-throughput sequencing method facilitating quantification of gene expression in a precisely manner. Development of RNA-Seq technologies and their extensive data-analysis methods make investigation of regulatory genes and functional gene annotations possible under specific conditions. In this study, we reveal the whole transcriptome profiles of the lesioned hemispheres of the zebrafish telencephalon at early wound healing (1 day post-lesion), early proliferative (3 day post-lesion) and differentiation (14 day post-lesion) stages of regeneration.