PRJNA563992
Three transcriptional regulators positively regulate polycyclic tetramate macrolactams biosynthesis in Streptomyces xiamenensis 318
Streptomyces xiamenensis 318 produces considerable amount of PTMs at 30 °C but the production of PTMs was almost blocked at 37 °C. Transcriptional regulators involved in the regulation of PTMs production were identified by comparative analysis of transcriptomes of different cultivation .