GSE125506
Gene expression for surgically treated pancreatic cancer after one neoadjuvant vaccine dose
RNA seq gene expression analysis of patients with resected pancreatic cancer following 1 dose of GM-CSF expressing whole cell pancreatic vaccine 2 weeks prior to resection. Samples were obtained for IHC analysis of protein expression, IHC analysis of immune cell infitration and RNA sequencing correlates Overall design: Data were used to make conclusions regarding the relationship of stromal expressed IDO, immune cell infiltration by IHC and the gene expression of different interluekins to describe pathways modified by IDO inhibitor treatment. Pending publication. IHC slides of each tumor case was obtained. Dissecting microscope was used by pathologist to obtain stroma. RNA were obtained, RNA sequencing was performed.