GSE203386
A therapeutically targetable NOTCH1-SIRT1-KAT7 axis in T-ALL
C57BL6 mice harboring Sirt1 conditional knockout NOTCH1-DE-induced leukemias were treated with vehicle (control) or tamoxifen to induce isogenic deletion of Sirt1. Here we report the H4K12ac ChIP-seq epigenetic profile of leukemic blasts obtained from the spleen from control- or tamoxifen-treated leukemic mice. Overall design: Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for histone modification H4K12ac in mice