PRJNA521529
A physiological and pathological role of RUNX1 as recombinase cofactor
The aim of the study was to evaluate the relevance of Runx1 activity as a recombinase cofactor for the proper rearrangements of the TCRbeta gene locus.TCRbeta rearrangements in thymus and spleen of a Runx1 knockout model and wildtype mice were analyzed.