GSE183235
ATAC-Seq to profile the chromatin accessibility in colonic macrophages from Tle4KO (Tle4fl/fl, Lyz2-Cre) and WT (Lyz2-Cre) mice
We found that TLE4 maintained overall chromatin accessibility in colonic macrophages. Overall design: Colonic macrophages were sorted from untreated WT and myeloid cell-specic Tle4KO mice. Differential chromatin accessibility was analyzed by ATAC-Seq.