GSE132769
Assessing chromatin accessibility in WT and STAT4-/- ILC1s
STAT4 dynamically interacts with the genomic landscape and functions in modulating chromatin accessibility to influence gene expression.  We aimed to evaluate the impact of STAT4 on chromatin accessibility of colonic lamina propria ILC1s. To address this aim, we sorted ILC1s from the colonic LP of unmanipulated C57BL/6 and STAT4-/- mice and performed the assay for transposase-accessible chromatin using sequencing (ATAC-seq). Overall design: Chromatin accessibility profiles of ILC1s isolated from the colonic lamina propria of WT and STAT4-/- mice, in duplicate.