GSE168245
A Critical Role of KCNQ1 in Human ß-Cell Developmen
We report the KCNQ1 mutation (permant neonatal diabete patient's KCNQ1 homozygous point mutation) negatively affected the expression of the metabolic genes of ß-like cells, especially at their late stage. Overall design: We examine differently expressed genes present in both mutated colonies and were also differently expressed from wild-type (WT) and unmodified-control (UC) of hESCs_H1-derived pancreatic ß cell-like organoids.