PRJNA492854
Genomic and transcriptomic characterisation of undifferentiated pleomorphic sarcoma of bone
This study represents the first comprehensive WES and RNA-Seq analysisof UPSb tumours revealing novel protein-coding recurrent gene mutations, gene fusionsand identifying a potential UPSb molecular biomarker, thereby broadening theunderstanding of the pathogenic mechanisms and highlighting the possibility of developing novel targeted therapeutics.