PRJNA718709
Genomic heterogeneity and clonal evolution in human gastroesophageal junction cancer revealed by single cell DNA sequencing Raw sequence reads
This study use single cell DNA sequencing to determine genomic variations and clonal evolution related to lymph node metastasis. Multiple Annealing and Looping Based Amplification Cycles (MALBAC) and bulk exome sequencing were performed to detect single cell copy number variations (CNVs) and single nucleotide variations (SNVs) respectively.