GSE184394
Role of SIRT1 in NAMPT-induced liver gene expression
We tested they hypothesis that hepatocyte SIRT1 mediates transcriptomic changes induced by hepatocyte-specific NAMPT overexpression Overall design: We overexpressed NAMPT in western diet-fed WT and SIRT1 liver-specific knockout mice for 12wk and subjected liver tissue to high-throughput RNA sequencing