GSE112194
Joint single-cell chromatin and protein profiling reveals environmental regulation of epigenomic heterogeneity [4T1-Splenocyte]
A novel scATAC-seq approach, Multi-Index single cell ATAC-seq (MI-ATAC), in which we not only index the accessible chromatin of individual cells, but also index their protein expression using index Fluorescence Activated Cell Sorting (FACS). Overall design: Freshly isolated splenocytes were fixed, permeabilized and stained against CD45, then sorted into single wells of a 96 well plate for MI-ATAC