GSE108406
MDM2 inhibitors reverse the transcriptional effects of DMKG plus B87.
We reported for the first time that DMKG plus B87 kills cancer cells through a MDM2-dependent cell death mechanism (unpublished results). Moreover, we demonstrated that this effect is reverted by MDM2 inhibitors. We investigated if this effect is transcriptional. Overall design: We compared different treatments in order to evaluate the transcriptional impact on cell death.