PRJNA794185
CRISPR-Cas9 Screen With Group B Streptococcus Beta-Hemolysin/Cytolysin and Streptococcus intermedius Intermedilysin
We conducted a whole genome CRISPR-Cas9 screen in HeLa cells to identify host genes that might contribute to pore formation and cell death after treatment with beta-hemolysin/cytolysin (Bhc) from group B Streptococcus (GBS) or intermedilysin (ILY) from Streptococcus intermedius.