PRJNA563895
mRNA sequencing in B lymphocytes in IgA nephropathy
Immunoglobulin A nephropathy (IgAN) is the leading cause of end-stage kidney disease. In circulation, CD19+ B lymphocytes are the major cells for IgA1 production. Therefore, we isolated CD19+ B lymphocytes to detect the different mRNA expression levels in patients with IgAN to explore the underlying pathogenesis of IgAN.