GSE126261
Single-cell combinatorial indexing ATAC-seq of HCC1143 with MEK, PI3K, and BET inhibition
We performed single-cell combinatorial indexing ATAC-seq on the basal-like TNBC cell line HCC1143 under MEK, PI3K, BET and combination treatments as well as DMSO controls Overall design: Cells were cultured and exposed to inhibitors or vehicle for 72 hours and processed in a single batch of sci-ATAC-seq using transposition barcodes for sample tracking to eliminate batch effects downstream