GSE121257
Acute depletion of CTCF directly affects MYC regulation through loss of enhancer–promoter looping
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. Gene expression of CTCF in human cancer cells and control uncover the disrupted enhancer-promoter regulation of MYC in human cancer cells. Overall design: CaptureC libraries constructed on two CTCF AID homozygous knock-in clones 27 and 35.