GSE184243
RNA-seq of isogenic NPC1 mutant iPSC-derived microglia like cells
Expression data comparing the effect of I1061T NPC1 mutation and anti-CD22 treatment in iPSC-derived microglia like cells treated with NPC patient CSF. Overall design: WT or I1061T mutant iPSC-derived microglia-like cells were treated with NPC patient CSF and isotype or anti-CD22 antibodies for 24 hours prior to bulk RNA extraction