PRJNA448654
Transcriptional response to PORCN inhibition using an HPAF-II orthotopic model upon MYC perturbation
Timecourse to investigate drug response in an orthotopic model of RNF43 mutant PDAC in different cell lines with different MYC states (WT, MYC OE, MYC T58A). RNA-seq performed at multiple timepoints (0 hrs, 8 hrs, 56 hrs)