GSE162033
Single-cell RNA-seq of long bone epiphyses from control and Sox9 mutant mice
Using a conditional inactivation approach in the mouse, we examined the importance of SOX9 in adult growth plate and articular cartilage. We specifically investigated the roles of SOX9 in the expression of the pancartilaginous, growth-plate and articular programs and in maintaining the chondrocyte lineage fate. Overall design: Examination of articular and growth plate chondrocytes mRNA profiles of 3-month-old control,  Sox9 mutant and Sox8 and Sox9 mutant mice.