PRJNA381352
Sus scrofa Raw sequence reads
Xist is an X-linked, non-coding gene responsible for the cis induction of X-chromosome inactivation (XCI). Knockout of the Xist allele on an active X chromosome abolishes erroneous XCI and enhances the in vivo development of cloned mouse embryos by more than tenfold. This study aimed to investigate if a similar manipulation would improve cloning efficiency in pigs.