DRP006789
Echinococcus multilocularis miRNA analysis
Alveolar echinococcosis (AE) is a zoonosis caused by the metacestode of Echinococcus multilocularis. Draft genome analysis of E. multilocularis showed that approximately 86% of its genome is non-coding. Micro RNAs (miRNAs) are small non-coding regulatory RNAs, and recent studies on parasitic helminths seek miRNAs as a new target for drug development and diagnostic markers. This study was designed to characterize miRNA profiles in E. multilocularis Nemuro strain using mice perorally infected with the parasite eggs via small RNA-seq.