PRJNA737169
Honokiol ameliorates heart failure post myocardial infarction through UCP3 mediated reactive oxygen species inhibition
RNAseq results revealed that HK restored the transcriptome changes to a certain extent and significantly enhanced the expression of mitochondrial inner membrane uncoupling protein isoform 3 (Ucp3), a protein that inhibits the production of mitochondrial ROS, protects cardiomyocytes, and relieves heart failure after MI.