GSE169374
MYC-deficiency impairs the development of effector/memory T lymphocytes
Using scRNA-seq we investigate the impact of the absence of MYC on physio-pathological development of PTEN-proficient or PTEN-deficient T lymphocytes.  We demonstrate that MYC-deficient effector/memory T cells is drastically reduced. MYC is then essential for effector/memory differentiation Overall design: Single cell RNA-seq study of T lymphocyte differentiation in Pten and/or Myc deleted mice