PRJNA796842
Long-term observation after transplantation of cultured human corneal endothelial cells for corneal endothelial dysfunction
We cultivated HCECs by the use of a conditioned medium fromorbital adipose-derived stem cells (OASC-CM) in vitro . Then the HCECs were usedto treat animal corneal endothelial dysfunction models via cell transplantation.We carried out a 24-month postoperative preclinical observation and verified the long-term effect byhistological examination and transcriptome sequencing.