GSE192923
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre Livers Transcriptomes
Conclusion: Elf4fl/fl-Villin-Cre mice are more sensitive to alcohol induced liver steatosis Overall design: six-week-old WT and Elf4fl/fl-Villin-Cre C57BL/6 male mice were treated with Lieber-DeCarli liquid diet containing 5% (w/v) alcohol (EtOH) or isocaloric maltose dextrin (Ctrl) for 21 days. Livers was taken out and the RNA was extracted by Trizol method, followed by eukaryotic RNA-seq and associated analysis