GSE97410
Effect of INO80 loss on open chromatin in HepG2 cells [ATAC-seq]
Loss of INO80 from INO80 canonical bound regions decreases open chromatin. Loss of INO80 did not affect chromatin accessibility at autonomous sites. Overall design: Two indepdent siRNAs targeting INO80 were used to deplete HepG2 cells followed by ATAC-seq library preparation as described in Buenrostro et al. 2013). Data were generated from three independent siRNA transductions.