GSE178419
HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA
Our study delineates a novel mechanism for HuR-mediated posttranscriptional regulation of myogenesis that requires its association to YB1 and provides new insights into the central role of posttranscriptional regulatory networks in modulating vital cellular processes such as myogenesis. Overall design: Putative mRNA targets of HuR and YB1 in muscle cells were identified by performing RIP-seq experiments using the Illumina NextSeq 500 platform