GSE130277
MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2
In this study we report differences between MeCP2 isoforms (DNA binding ability, degradation rates and genomic binding) that reflect non-overlapping functions of the 2 proteins. Overall design: ChIP seq of MeCP2 isoforms E1 and E2in mice frontal cortexes euthanized at 2 different times of the day (12 a.m. and 12 p.m.)