GSE138981
Analysis of NSL knockout brains
In the current study, we analyse the function of MOF-NSL complex in neural cells. We find that the NSL complex regulates metabolic networks in the brain. Overall design: Knockout of NSL complex members Mof, Kansl2 and Kansl3 was induced using the Nestin Cre. Neural cells, endothelial cells, pericytes and microglia were isolated by FACS. Gene expression analysed by RNA seq. and chromatin landscape via ChIP seq.