GSE158652
Next Generation Sequencing Facilitates Quantitative Analysis of the effects of ICAM-1 on lung ILC2 Transcriptome
ICAM-1 modulates cytokine expression in ILC2s. While it downregulates the expression of ILC2 key cytokines il5, il13 and il9, it upregulates that of il10. Overall design: mRNA profiles of sorted mouse activated lung ILC2s from C57BL/6 and ICAM-1 mice were generated by deep sequencing, in duplicates, using a NextSeq 500 (Illumina) system.