Role_of_early_life_gut_microbiota_in_colonisation_resistance_development-sc-3258
Role_of_early_life_gut_microbiota_in_colonisation_resistance_development
The aim is to understand how (i) bifidobacteria colonise the gut and (ii) subsequently modulate critical colonisation resistance, and to understand how (iii) early life antibiotic-induced disturbances alter this microbial community, ultimately leading to a breakdown in pathogen protection. Another key goal is to (iv) identify bifidobacterial communities that can restore a disturbed early life microbiota back into one able to control gut infection. These data are part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
Several approaches will be used to investigate the role of early life gut microbiota.