Exome_sequencing_of_the_Nrbp1_tumours-sc-2011-01-11
Exome_sequencing_of_the_Nrbp1_tumours
We have developed a mouse model whereby we can conditionally delete the Nuclear Receptor Binding Protein 1 (Nrbp1) in the mouse intestine. From these mice we have collected tumours. In this experiment we will sequence the exome of these tumours to identify mutations that co-operate with loss of Nrbp1 in tumorigenesis. . This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
We have developed a mouse model whereby we can conditionally delete the Nuclear Receptor Binding Protein 1 (Nrbp1) in the mouse intestine. From these mice we have collected tumours. In this experiment we will sequence the exome of these tumours to identify mutations that co-operate with loss of Nrbp1 in tumorigenesis.