GSE177635
Brown adipose tissue monocytes support tissue expansion
We report that monocytes contribute to the maintenance of BAT macrophages in a dynamic manner at steady state, and allow tissue remodelling during BAT expansion. Using scRNA-Seq, we explored monocyte and macrophage diversity in BAT at steady state and during BAT expansion. Overall design: Brown adipose tissue CD45+ cells from AdipoQcre-ERT2 ATGLfl/fl and control mice were cell sorted and analyzed by single-cell RNA sequencing.