ena-STUDY-CHALMERS UNIVERSITY OF TECHNOLOGY-19-10-2016-09:46:14:528-736
Combined genome and transcriptome sequencing to identify plant cell wall degrading enzymes in the thermophilic fungus Malbranchea cinnamomea
The thermophilic fungus Malbranchea cinnamomea is a promising source of thermostable, industrially relevant biocatalysts, in particular plant cell wall active or carbohydrate active enzymes. We report here the genome sequencing of M. cinnamomea strain FCH 10.5, newly isolated from compost of a waste treatment factory in Vietnam, and the analysis of its repertoire of plant cell wall degrading enzymes. In combination with transcriptomics, genes differentially expressed during growth on wheat bran and beechwood xylan were identified. This study will set the basis for systematically using the full potential of the M. cinnamomea enzyme system for applications in biorefinery processes.
The thermophilic fungus Malbranchea cinnamomea is a promising source of thermostable, industrially relevant biocatalysts, in particular plant cell wall active or carbohydrate active enzymes. We report here the genome sequencing of M. cinnamomea strain FCH 10.5, newly isolated from compost of a waste treatment factory in Vietnam, and the analysis of its repertoire of plant cell wall degrading enzymes. In combination with transcriptomics, genes differentially expressed during growth on wheat bran and beechwood xylan were identified. This study will set the basis for systematically using the full potential of the M. cinnamomea enzyme system for applications in biorefinery processes.