GSE210217
Grainyhead-like 2 influences renal cyst growth in a mouse model
To characterize GRHL2 as a potential progression modifier and therapeutic target in autosomal-dominant polycystic kidney disease. Overall design: Kidneys of wildtype, Grhl2 knockout, and Myc overexpression mice were characterized using histology, immunnofluorescence, Western blotting, RT-qPCR, and RNA-sequencing.