PRJNA542504
ATAC study of PTL-Her2-CAR-T and Her2-CAR-T cells isolated from tumor tissues
To compare the gene loci of gene expression between the PTL-Her2-CAR-T cells and Her2-CAR-T cells, SKOV3-bearing NSG mice were injected with different CAR-T cells via tail. At 28 days after CAR-T-cells infusion, mice were euthanized and tumor tissues were resected. The tumor was divided and tumor infiltrating CAR-T cells were separated for ATAC-seq.