PRJNA803979
Mus musculus cultivar:C57BL/6 Raw sequence reads
YAP is a downstream effector of the Hippo pathway, which was originally identified as a regulator of organ size in Drosophila. The Hippo pathway is highly conserved in mammals. The pathological roles of YAP overactivation in tubular injury, renal fibrosis and even renal cell carcinoma have been identified, however the physiological functions of YAP in the kidney are still unknown. We explore the role of YAP in kidney use YAP kidney knockout mice.