PRJNA676037
Altered methylation patterns of CpG islands after CRISPR-mediated genome modification
The methylomes of DNA extracted from mouse spleen tissues from CRISPR-edited mouse strains with genome modifications mediated by homology-directed repair and non-homologous end-joining along with their control strains were evaluated using whole genome bisulfite sequencing. These data were utilized to evaluate the impact of embryonic CRISPR-mediated genome modifications on the epigenome.