PRJNA665995
Higher-order chromatin structures of chromosomally-integrated HHV-6A predict Integration Sites
We used RNA-sequencing to investigate the silencing of HHV-6A during the establishment of a latent infection and 4C Sequencing to explore the genome-wide chromatin contacts of the integrated HHV-6A in latently infected cells. We further implemented long-read minION sequencing in the 4C-seq assay and developed a method to identify HHV-6A/B integration sites in clinical samples.