GSE99658
Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function
Using RNAseq we describe transcriptional changes downstream of liver-specific knockout of RNaseH1, including effects on mitochondrial function, fibrosis and cell cycle Overall design: We perform RNAseq on mouse livers under conditions of constitutive or inducible knockout of RNaseH1