GSE209886
LSD1 inhibition disrupts super-enhancer activities in CRPC [ChIP-seq]
Our studies revealed a novel oncogenic function of LSD1 in driving PCa progression by activating MYC signaling and mediating CRPC SEs activities, cotargeting LSD1 and BRD4 achieved significant synergistic effects in repressing CRPC tumor growth Overall design: BRD4 ChIP-Seq were performed in LNCaP cells cultured in 5% CSS. All ChIP-seq samples contain replications.