GSE134488
Transcriptomic analysis of the soleus muscle extracted from Dnm2 K562E point-mutant heterozygous mice
RNA sequencing was performed to evaluate the impact of Dnm2 K562E mutation in the soleus muscle. The assessment of the dataset reveals a large number of differentially regulated transcripts between animals of both genotypes. This is consistent with a dominant phenotype caused by the Dnm2 K562E point mutation on the muscle. Overall design: The dataset includes sequenced RNA extracted from soleus muscle of mice aged to 2 months. Soleus muscles were obtained from 4 independent male mice per genotype. The genotypes analyzed include controls (Dnm2+/+) and Dnm2 K562E point-mutant mice (Dnm2 +/K562E).