GSE176221
Next-generation sequencing of tumors with oral squamous cell carcinoma
Comparing the differentially expressed genes between OSCC tumors with lymph-node metastasis (LNM) and those without LNM, which were obtained though NGS, we found that immune response plays an important role in the process of OSCC LNM and the candidate genes involved in the anti-tumor immunity were validated with qRT-PCR. Overall design: mRNA profiles of OSCC patients with LNM (n=5) and those without LNM (n=4).