GSE162907
Comparison of brown adipose tissue (BAT) gene expression between Letmd1 KO and wild-type control mice housed at 30°C or 7°C for 3 weeks.
We identified Letm1 domain containing 1 (Letmd1) as a candidate regulator of BAT thermogenesis. We generated Letmd1 KO mice, raised at thermoneutral or cold conditions, and performed RNA-sequencing in BAT. Overall design: Transcriptome profiles of BAT of adult Letmd1 KO and wild-type mice housed at 30°C or 7°C for 3 weeks.