DRP004088
High throughput analysis of miRNA competition between EBV and encogenious transcripts
MiRNAs bind to 3'' UTR of target mRNAs, result in mRNA destabilization or translational repression. Recent studies show that common target of one miRNA are competed and control the other one. The mechanism are termed as "competing endogenous RNA (ceRNA)". In case of EBV infected cells, there are about 10 exogenous transcripts are derived from the EBV. It is possibly that the RNA compete with common miRNA target of endogenous RNA. In this experiments examined to reveal the ceRNA network in EBV infected cells.