PRJNA804486
Effects of stiffness on differentiation of stem cells into valve endothelial cells
Through mRNA sequencing, we determined the key genetic markers involved in stiffness guiding the differentiation of cardiac progenitor cells into h-iVECs. Unsupervised hierarchical clustering showed that soft and medium substrates were more suitable for the differentiation of h-iPSCs into h-iVECs in vitro.