GSE117497
RNA-seq transcriptome analyses in T47D cells treated with ActA and Palbociclib.
We performed SMAD2 ChIP-seq analysis in T47D cells with/without Palbociclib treatment. To validate whether the changes in SMAD2 binding to the genome indeed resulted in changes in target gene expression, we performed RNA-seq transcriptome analyses in T47D with/without ActA stimulation and Palbo treatment. Overall design: RNA-seq transcriptome analyses performed in estrogen receptor positive breast cancer T47D with/without ActA stimulation and Palbo treatment.