GSE122055
DEGs in the bone marrow of Esr1Nkx2-1Cre females
Disrupting central estrogen signaling exposes a powerful sex-dependent brain-to-bone axis in female mice triggering massive increases in bone density. Overall design: Comparison of wild type bone marrow from female (Esr1flox/flox) mice compared to the bone marrow of mutant (Esr1fl/fl;Nkx2-1Cre) female mice at 4 weeks of age.