GSE125202
Transcriptomic profile of cohesin proficient and deficient cells
The goal of this study is to identify the mechanism underlying the notion that loss of cohesin complex could sensitize tumor cells to anti-PD-1 therapy. Overall design: mRNA profiles of WT, NIPBL Knockout, SMC1A knockdown HCT116 cells and WT, Nipbl knockout, Stag2 knockout CT26 cells were detected by RNA-Sequencing. Duplicate for each knockout or knockdown group.