PRJNA872173
M. tuberculosis outbreak strain RNA seq
In vitro RNA sequencing was carried out on broth grown Lineage 4 H37Rv (control) and a Lineage 1 outbreak strain, NCG, to characterize the expression profiles of the two strains. In particular, this experiment is relevant to our study on a ESX-5 secreted factor, EsxM. We sought to identify any differences in expression amongst the ESX-5 paralogs when comparing strains of different lineages.