PRJNA677840
Cell type-specific transcriptomic and eipgenome analysis of diabetic cardiomyopathy
We isolated cardiac myocytes, endothelial cells, fibroblasts, monocytes and macrophages from mouse hearts by fluorescence-assisted cell sorting and performed RNA-seq and whole genome bisulfite sequencing experiments. Diabetes was induced using streptozotocin in adult mice to induce diabetes prior to cell type specific analysis.