GSE114018
HNF4a Pathway Mapping Identifies Wild-type IDH1 as a Targetable Metabolic Node in Gastric Cancer
Comprehensive downstream mapping of HNF4a revealed its role in regulating GC metabolism via regulation of IDH1 Overall design: HNF4a ChIP-seq of GC cell lines, RNA-seq data of HNF4a perturbation and transcritome primary GC dataset were integrated to reveal HNF4a regulating biological processes and targets in GC, thus provide new therapeutic opportunity.