PRJNA672247
GJA1 Raw sequence reads in CSVD patients
Cx43 is fully expressed across the central nervous system, especially in endothelial cells and vascular smooth muscle cells which are important components of the blood brain barrier. We performed next-generation sequencing of the Cx43 coding gene (GJA1 gene) in cerebral small vessel disease (CSVD) patients to examine correlation between GJA1 gene SNPs and brain MRI topography in CSVD.