GSE161338
Comparative transcriptomic analysis between wild-type (WT) and Cables2-null embryos.
We found that conventional targeted disruption of the entire Cables2 locus caused post-gastrulation embryonic lethality in mouse. To examine global gene changes during gastrulation, we performed the RNA-seq experiment using WT- and Cables2-null embryos at embryonic day 6.5 and 7.5. Overall design: mRNA profiles of WT- and Cables2-null mouse embryos at E6.5 and E7.5