GSE193914
Single cell RNA sequence analysis of murine alveolar macrophages in the presence of lung cancer cells
To classify the cell population of lung alveolar macrophages in the presence (or absence) of lung cancer cells in vivo, single cell RNA sequence analysis was performed using orthotopic tumor bearing animal model with C57BL/6 mice and Lewis Lung Carcinoma (LLC) cells. CD45+, F4/80+, Siglec-F+ population was sorted as alveolar macrophage population with fluorescence-activated cell sorting (FACS) technique. Overall design: Single cell RNA sequence analysis of murine alveolar macrophages in the presence of lung cancer cells