PRJNA256123
Gut microbiota signature in Behçet syndrome patients
Behçet syndrome is a systemic inflammatory condition characterized by muco-cutaneous and ocular manifestations, with central nervous system, vascular and/or gastro-intestinal involvement. The association of microbiota with Behçet syndrome has been suggested several times, but not shown yet. This project is aimed to compare the gut microbiota structure in Behcet syndrome patients and healthy control relatives. We sequenced the fecal microbiota of 22 patients with Behçet syndrome and that of 16 healthy co-habiting controls, sharing the same diet and life style by 454 barcoded pyrosequencing of the V3-V4 hypervariable regions of the 16 rDNA gene.