GSE209757
The oncometabolite D-2HG alters T cell metabolism to impair CD8+ T cell function
The tumor-derived oncometabolite D-2HG impairs CD8+ T cell function through a novel metabolic target Overall design: We performed RNA-seq profiling on CD8+ T cells activated for 6 hours in the presence of D-2HG, L-2HG or left untreated (N=3).