GSE124610
Loss of hydroxymethylcytosine is an independent adverse prognostic factor in clear cell Renal Cell Carcinoma (ccRCC) and can be abrogated by ascorbic acid mediated TET activation
The experiment was performed to study high resolution gene specific changes induced by Ascorbic acid tretament in clear cell RCC cells (786-0 cell line) Overall design: 786-O ccRCC cells were treated either with control (catalase) or with catalase+ ascorbic acid. BS and OxBS were performed in both.