Burkholderia pseudomallei serial patient-sc-2010-04-08
Burkholderia pseudomallei serial patient
For further information on this study please see                 http://www.sanger.ac.uk/resources/downloads/bacteria/burkholderia-pseudomallei.html                 This data is part of a pre-publication release. For information on the proper use of                 pre-publication data shared by the Wellcome Trust Sanger Institute (including                 details of any publication moratoria), please see                 http://www.sanger.ac.uk/datasharing/
"Microevolution of Burkholderia pseudomallei during an acute infection."                 Pubmed ID 24966357. We used whole-genome sequencing to evaluate 69 independent                 colonies of Burkholderia pseudomallei isolated from seven body sites of a patient                 with acute disseminated melioidosis. Fourteen closely related genotypes were found,                 providing evidence for the rapid in vivo diversification of B. pseudomallei after                 inoculation and systemic spread.