PRJNA771418
A study of differential functions of LMO2 in placental trophoblast cells and its association with preeclampsia
The inadequate trophoblast invasion and abnormal remodeling of spiral artery is associated with the development of preeclampsia (PE). Considering that LMO2 (LIM-domain only 2) is a key regulator for vascularization and selectively expressed in some of the trophoblasts, we aimed to explore the functional role of LMO2 in trophoblast cells and to examine the underlying mechanism.