GSE130110
CD8+ T Cells Promote Maturation of Liver-Resident NK Cells via the CD70-CD27 axis
We discovered that LrNK cells exhibit a relatively immature phenotype and impaired cytotoxic capacity in the absence of CD8+ T cells. The provision of CD8+ T cells to Cd8-/- or Rag1-/- mice led to the restoration of LrNK cell maturation Overall design: LrNK  and cNK mRNA profiles of  wild type (WT) and CD8-/- mice were generated by deep sequencing, in triplicate, using Illumina