GSE122268
Epigenomes of oxLDL exposed trained monocytes
Innate immune memory is the phenomenon whereby innate immune cells such as monocytes or macrophages undergo functional reprogramming after exposure to microbial components.  In this study we apply epigenetic, H3K27ac and H3K4me3 ChIP-seq, analysis to healthy human monocytes exposed to oxidized Low Density Lipoprotein (oxLDL), in vitro. Overall design: Monocytes from healthy donors were cultured in vitro for 24 hours with media or oxLDL