Genomics_of_methotrexate_resistance_in_HeLa-sc-4179
Genomics_of_methotrexate_resistance_in_HeLa
Study of HeLa subclones exposed to methotrexate to generate resistance.
Study of HeLa subclones exposed to methotrexate to generate resistance. The sequenced samples show a range of different mechanisms of resistance, including double minutes & homogeneously staining regions for the DHFR gene; gain of 5q, and unknown mechanisms.