GSE178433
ChIP-seq profiling of H3K4me3, H3K27ac, H3K27me3, V5-HOXA9-AM, and V5-ER-HOXA9-AM cells before and after inducing irreversible commitment to myeloid differentiation
Data reveal epigenome-wide trends in histone modifications and Hoxa9 binding sites associated with irreversible commitment from the GMP-like state to the neutrophil-like state Overall design: ER-Hoxa9 cells cultured with estradiol, 120 hours without estradiol, or with estradiol after pre-treatment with four different durations of estradiol withdrawal