GSE176409
RNA sequencing of Hoxb8 yolk sac- and bone marrow-derived
Progenitor cells of yolk sac and bone marrow origin were transduced with an estrogen receptor Hoxb8 fusion protein to generate stable cell lines. Macrophages were differentiated with M-CSF in the absence of estrogen, and then stimulated with IL-4 or LPS. Hoxb8 progenitor cells and differentiated macrophages were analyzed by RNA sequencing. Overall design: RNA profile of YS vs. BM Hoxb8 cell lines (progenitors and differentiated macrophages - unstimulated/ IL4-/ LPS-treated for 5 hours