PRJNA551130
Induction of adult cardiomyocyte renewal by Klf1
In highly regenerative animals, cardiac regeneration occurs innately through cardiomyocyte dedifferentiation and proliferation, although the regenerative mechanisms remain unclear. This project contains raw sequencing data sets that were used to identify that klf1, a Kruppel-like transcription factor essential for red blood cell development, is also necessary and sufficient in the myocardium for the induction of cardiomyocyte dedifferentiation and proliferation in adult zebrafish hearts