GSE115131
Overexpression of chicken IRF7 increased viral replication and programmed cell death to the avian influenza virus infection through TGF-beta/FoxO signaling axis in DF-1
To elucidate the functional role of chicken IRF7 against avian influenza virus (AIV) infection, we generated inducible IRF7 overexpression DF-1 cell lines that could fine control the IRF7 expression level and performed in vitro infection using low pathogenic AIVs (LPAIVs) followed by RNA-seq. Overall design: Transcriptiome analysis of either low pathgenic influenza virus (H6N2) or mock infected chicken IRF7 overexpression DF-1 cell lines and  respective control cell line