PRJNA495704
Danio rerio strain:Tubingen Transcriptome or Gene expression
Scaffold Matrix Attachment Region 1, SMAR1 is a characterised nuclear matrix binding protein. It is thought to be a mammalian protein that plays role in a various nuclear functions. In the present study, we have identified and characterised SMAR1 homologue in zebrafish (zSMAR1) of 2.43 Kb length consisting of 13 exons that encodes a 508 amino acid long protein. zSMAR1 shares 66% homology to mouse SMAR1. Morpholino antisense oligonucleotide (MO) mediated knock-down of zSMAR1 in fish embryos led to embryonic malformations - smaller head size, pericardial edema and a linear heart tube phenotype indicating its role in fish embryogenesis. The present RNA-Seq data is generated on Illumina NextSeq 500 platform yielding 75 nucleotide long reads in paired-end format. The samples used for sequencing are Control MO injected and MO targeting zSMAR1 injected zebrafish embryos.