GSE111341
Transcriptome profile Carnegie Stage 22 gut of different RET haplotypes
Total mRNA seq was perfomed on human fetal gut tissue at CS22 on 3 samples having different RET haplotype which progressively reduce expression of RET. R haplotypes are resistant and S haplotypes are susceptible to Hirschsprung disease Overall design: Total RNA from 2 replicates each of wildtype (RR), heterozygous (RS) and homozygous (SS)  embryonic gut was converted to cDNA  and run on HiSeq 2000 (100 bp paired end). R haplotypes are resistant and S haplotypes are susceptible to Hirschsprung disease.