GSE210033
3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances the TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury
This study investigated the therapeutic value of a candidate CRM, 3,4-dimethoxychalcone (3,4-DC), in functional recovery after SCI and its underlying mechanism.  RNA sequencing was used to identify the mechanisms of 3,4-DC in SCI. Overall design: Comparative gene expression profiling analysis of RNA-seq data for SCI group and SCI+3,4-DC group