GSE158193
Identification of noncoding RNA expression profiles following traumatic spinal cord injury by  high-throughput sequence analysis
To systematically profile and characterize the noncoding RNA (ncRNA) expression pattern in the lesion  epicenter of spinal tissues after traumatic spinal cord injury (TSCI). We used RNA-Seq to profle the expression and regulation patterns of noncoding RNAs and mRNAs of mice  models after TSCI. A total of 498 circRNAs and 1203 mRNAs were identified in TSCI mice  models to be differentially expressed. noncoding RNAs might play important roles via the competing endogenous RNA regulation pattern  after TSCI, further findings arising from this study will not only expand the understanding of potential ncRNA  biomarkers but also help guide therapeutic strategies for TSCI. Overall design: Spinal cord ncRNA profiles of 8-week old C57BL/6 mice with/without traumatic spinal cord injury