GSE118074
Genome-wide maps of ?NLef1 in primary mouse keratinocytes
In adult K14?NLef1 mouse, the overexpression of ?NLef1, a ß-catenin dominat negative, in basal keratinocytes leads to the conversion of hair follicles into multilayered epithelial cysts and ectopic sebaceous gland. To uncover direct target genes of ?NLef1 we performed ChIP-Seq experiments. Overall design: Examination of ?NLef1 genomic targets in mouse primary keratinocytes