GSE168550
Single cell RNA sequencing of liver macrophages from Noonan mice
We report the use of single cell RNA sequencing to identify differentially-expressed genes in liver macrophages from a mouse model of Noonan syndrome (NS) and highlight specific subpopulation clusters that may contribute to the associated insulin resistance phenotype. Overall design: Single cell RNA sequencing of F4/80+ cells purified by flow cytometry from liver of wild type and Noonan mice