GSE117078
The Transcription factor Zeb2 ia required to maintain tissue-specific identities of macrophages [bulk RNA-seq]
Microarray, Bulk RNA Sequencing and Single cell RNA Sequencing of different murine tissue-resident macrophage populations to assess role of Zeb2 and LXRa Overall design: Bulk RNA Seq = Replicates of ZEB2KO alveolar macrophages (sorted on CD11b expression) and ZEB2KO Kupffer cells (sorted on Tim4 expression) were compared with replicates of WT Alveolar Macs and Kupffer cells. This data was used to define core Alveolar Mac and Kupffer Cell profiles as well as core profies of other macrophages from previously published data.