DRP008178
Dietary Lactobacillus-derived exopolysaccharide enhances immune checkpoint blockade therapy
Dietary EPS-R1 (microbial exopolysaccharide produced by Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1) consumption induces CCR6+ CD8+ T cells in Peyer's patches, favoring a tumor microenvironment that augments the therapeutic effect of immune checkpoint blockade depending on CCL20 production by tumors.