GSE169185
RNA-seq analysis of CREB3L2 dimers in Hippocampal Neurons
To investigate differential gene expression profiles mediated by CREB3L2 transcription factor dimers in order to assess their differential contribution to Alzheimer's disease pathogenesis. Overall design: Rat primary hippocampal neurons were infected with different CREB3L2 dimers using lentiviruses. Specific dimer combinations were promoted using cheimically induced proximty. Total RNA extraction was performed after four days of incubation of this chemogenetic system. RNA-seq was employed to examine gene expression changes.