PRJNA765888
The effects and underlying mechanisms of mutated hepatitis B virus preS gene on the development of hepatocellular carcinoma
PreS fragments (WT/M2) or Vector were delivered into Fah deficient mice with Sleeping Beauty transposon system at 8-10 weeks of age . After 150 days, the mice were anesthetized with carbon dioxide and sacrificed. All the RNA from their liver or tumor are extracted for gene expression chips.