PRJNA428837
Impact of mutations on global gene expression in Ehrlichia chaffeensis.
Rickettsial pathogen Ehrlichia chaffeensis causes a tick-borne disease, human monocytic ehrlichiosis (HME). Mutations within certain genomic locations of the pathogen aid in understanding the pathogenesis and in developing attenuated vaccines. Assess the effect of mutations on the global transcriptional changes using RNA deep-sequencing technology.