GSE175795
RNA sequencing of adipose tissue-derived stromal cells (ADSCs) with or without Sal-B addition
Salvianolic acid B (Sal-B) is the most abundant and bioactive water-soluble compound in Salvia miltiorrhiza. Studies have shown that salvianolic acid B increases the mRNA expression of adipogenic transcription factors, including PPAR?, C/EBPa and PPARa, in 3T3-L1 preadipocytes to increase glucose uptake and mitochondrial respiration, reduce glycerol release and promote adipocyte differentiation. However, the effect of Sal-B on graft fat survival and its specific mechanism have not been investigated. So we dicided using h-ADSCs to see its transcriptomes changing after Sal-B addition. Overall design: Examination of h-ADSCs RNA sequencing comparing the Sal-B addition(50µmol/L, four days and eight days) group and control group