Evolution_of_pathogensis_in_Streptococcus_suis-sc-4467
Evolution_of_pathogensis_in_Streptococcus_suis
50 PacBio genomes of Streptococcus suis  1) This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute please see http://www.sanger.ac.uk/datasharing/
Bacterial pathogens very often have smaller genomes and fewer genes than their nearest non-pathogenic relatives. However, despite much speculation, it remains unclear why this pattern holds. Streptococcus suis has made several recent and independent transitions to pathogenicity, each associated with genome reduction. This research involves sampling whole genomes of global S. suis populations, developing new statistical models and collating functional data in order to conduct the first large-scale tests of the various hypotheses linking genome reduction and pathogenicity.??