PRJNA824936
The role of ZNF143 overexpression in rat liver cell proliferation
Zinc finger protein 143(ZNF143), a member of the Kruppel C2H2-type zinc finger protein family, is strongly associated with cell proliferation, cell cycle regulation, and cancer development. A recent study suggested that ZNF143 is a transcriptional activator that promotes hepatocellular cancer (HCC) cell proliferation and cell cycle transition. However, the exact biological role of ZNF143 in liver regeneration and normal liver cell proliferation has not yet been investigated.