GSE130132
Cynomolgus macaques treated with Divalent-siRNA (Di-siRNA) targeting Huntingtin gene
Examine potential off-target effects of HTT targeting siRNA in cynomologus macaque brains. Overall design: RNA-seq of brain punches from HTT targeting siRNA treated and non-treated cynomolgus macaques (N=4 per group). Three brain punches were taken from each animal and processed/sequenced as separate samples. Reads were processed and combined for analysis.