GSE108946
Transcriptome time course of mouse acute myeloid leukemia cells upon PU.1 restoration and knockdown
We have utilized advanced RNAi technology to dynamically restore and subsequently knock down endogenous PU.1 expression in p53-deficient AML cells, which respectively causes differentiation and de-differentiation Overall design: RNA-seq was performed on AML246 cells following Dox treatment or withdrawal over a 24 day time course