GSE65736
DNA methylation reprogramming during early embryogenesis in human
We provided base-resolution of DNA methylome of normal human gametes and early developmental embryos, including human MII oocytes, sperm, 8-cell embryos, morula, inner cell mass and postimplantation embryos. Our work will have important impact on human health. Overall design: MethylC-seq were performed with human gametes and early normal developmental embryos, including human MII oocytes, sperm, 8-cell embryos, morula, inner cell mass and postimplantation embryos. Each stage has at least two biological replications. RNA-seq were performed for placenta and six-week embryos..