PRJNA674464
The CRISPR-based C-to-T base editing system
The codon-optimized zAncBE4max construct contains the Uracil glycosylase inhibitor(UGI) and Deaminase (rAPOBEC1)-coupled Cas9a D10A nicknase, and NLS to enabe C-to-T base editing in the whole genome of zebrafish.