PRJNA659636
Effect of berberine on gut microbiota in mice with colorectal cancer
BBR altered the composition of gut microbiota in AOM/DSS mice obviously, which were characterized by a decrease of Actinobacteria and Verrucomicrobia significantly at the phylum level. At the genus level, it was able to suppress pathogenic species, such as f_Erysipelotrichaceae, Alistipes, and elevate some short chain fat acid (SCFA)-producing bacteria, including Alloprevotella, Flavonifractor, and Oscillibacter.