GSE126195
Structure of examined circular RNAs and some of their linear cognate RNAs
We optimized the SHAPE-MaP (selective 2'-hydroxyl acylation analyzed by primer extension and mutational profiling) assay to analyze structures of paired circular (circSHAPE-MaP) and linear (linearSHAPE-MaP) RNAs. Overall design: CircSHAPE-MaP and linearSHAPE-MaP for circRNA and linear RNA secondary structure.