GSE132196
LSD1 regulates splenic B cell chromatin accessibility
To understand the role of LSD1 in splenic B cell development, spleens from mice with B cell conditional deletion of LSD1 were harvested, B220+CD93–GL7–CD23–CD21hiCD1d+ marginal zone B cells and B220+CD93–GL7–CD23+CD21midCD1d– follicular B cells were FACS-sorted, and ATAC-seq was performed to identify LSD1-target regulated chromatin. Overall design: ATAC-seq on control or LSD1-deficient murine splenic marginal zone B cells and follicular B cells