GSE169095
Genome-scale CRISPR screen identifies TMEM41B as a critical host factor required for coronavirus replication [RNA-seq]
Explore the potential downstream signaling pathways that inhibit TGEV replication after knocking out TMEM41B by RNA-seq analysis. Overall design: For RNA high-throughput sequencing (RNA-seq), RNA libraries were created from each group, for example, TMEM41B KO cells (TMEM41B_KO_MOCK, TMEM41B_KO_TGEV) and WT cells (WT_MOCK, WT_TGEV). Three  replicates were conducted for each sample.