GSE174241
Tim-4+ Cavity-Resident Macrophages Impair Anti-Tumor CD8+ T cell Immunity [scRNA-Seq]
Here we report transcriptional and TCR specificities associated with PSlow and PShigh CD8 T cells. Overall design: Single cell TCR/RNA sequencing was performed on sorted PSlow and PShigh CD8 T cells from five MC38-LG bearing mice that had been treated with anti-Tim-4 and anti-PD-1. Cells from the individual mice were hashtagged to allow subsequent deconvolution.