GSE134366
Genome-wide analysis of chromatin accessibility in developing thymic Treg cells
We analyzed open chromatin regions in thymic Treg cells, their immediate precursors (CD25+ Foxp3-), and mature and semi-mature CD4 single positive cells. We wished to understand which chromatin regions become accessible in response to TCR-stimulation and then Foxp3 expression as Treg cells develop. Overall design: Examination of chromatin accessibility in developing CD4SP thymocyte subsets, including Treg cells and immediate precursors