GSE115378
Phospho-regulation of Atoh1 is required for plasticity of secretory progenitors and tissue regeneration    [colon]
To define Atoh1 secretory signature, transcriptional profiling of secretory cells was performed. The expression profile of Atoh1+ cells from Atoh1(WT)CreERT2 R26RtdTom mice was determined by comparing tdTom+ (secretory) and tdTom- (absorptive) cells to define the baseline pro-secretory signature for both colon and small intestine (SI). Overall design: A total of 8 mice were used for this experiment; TdTom+ and tdTom- populations were collected from each SI and colon.