GSE176084
Whole-genome mapping of ETV6-RUNX1 in pre-B lymphoblast models
Genome binding/occupancy profiling of ETS Variant Transcription Factor 6- Runt Related Transcription Factor 1 fusion protein (ETV6-RUNX1) in REH cells by high throughput sequencing. ETV6-RUNX1 is expressed in pediatric t(12;21) ETV6-RUNX1 B cell precursor acute lymphoblastic leukemia. Overall design: ETV6-RUNX1 genome-wide distribution is determined using ChIP-seq. Cells used in this study are pre-B lymphoblast REH cells. ChIP samples and libraries were done by Sérandour A.A and Debaize L. High-throughput sequencing was conducted on a Genome HiSeq1500/2500. The input, REH RUNX1 Chip-Seq and histone marks are deposited in GEO GSE117684.