PRJNA433707
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
we develop a recombination-based mutation barcoding (ReMB) library for impactful mutations conferring clonal advantage in proliferation and drug responses. The highest-ranking mutations in PIK3CA and PIK3R1 include previously reported deleterious mutations, as well as a number of mutations with unknown significance.