GSE182914
The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer
We report the effect of H19 knockdown on genome wide methylation by Enhanced Reduced Representation Bisulfite Sequencing (eRBBS) to detect quantitative base pair changes. Differential methylation genome wide analysis was done on NEPC derived organoid  expressing shH19 or a control vector. Overall design: Three replicates of organoids each expressing shH19 and and  control vectors were utilized for ERBBS assay for differential methylation.