GSE126464
WRN knockout effects upon gene expression in SW48 and OVK18
To determine gene expression changes upon CRISPR/Cas9-mediated WRN knockout in SW48 and OVK18. 72 hours after transduction of sgRNA into Cas9 expressing cells, RNA was harvested and submitted for sequencing. Overall design: Cas9 expressing SW48 and OVK18 cells were transduced with either a negative control sgRNA targeting an intergenic region of chromosome 2 (sgCh2-2), or one of two sgRNAs targeting WRN (sgWRN2, sgWRN3)