GSE122044
MiR-29 Regulates de novo Lipogenesis in the Liver and Circulating Triglyceride Levels in a Sirt1-Dependent Manner
Systematic comparison of multiple models of diabetes / insulin resistance reveals miR-29 as a commonality among them, and further analysis reveals it as a key therapeutic target for insulin resistance. Overall design: Comparison of multiple models of diabetes at the small RNA-seq and RNA-seq level. Further sequencing analysis of miR-29 following perturbation using locked nucleic acids.