PRJNA527341
Mucus and cell-penetrating peptides for improved transport across the sputum of cystic fibrosis patients and the underlying epithelia
We utilized phage display libraries and high throughput sequencing technologies to screen an unprecedented number of peptide coatings and select for mucus-penetrating peptides that penetrate through cystic fibrosis (CF) sputum from patients and achieve internalization in lung epithelial cells.