PRJNA662589
Raw sequence reads of SARS-CoV-2 from a prolonged infection
We describe a case of chronic COVID-19 in a patient with lymphoma and associated B cell immunodeficiency. Viral culture and sequence analysis demonstrate persistent SARS-CoV-2 replication for at least 119 days. The patient's lack of seroconversion and prolonged course illustrate the importance of antibodies in resolving SARS-CoV-2 infection. This case highlights challenges in managing immunocompromised hosts, who may act as persistent shedders and sources of transmission.