Schistosoma_mansoni_functional_genomics___histone_modifications__ChIP_seq_-sc-2012-08-10T13:29:51Z-2316
Schistosoma_mansoni_functional_genomics___histone_modifications__ChIP_seq_
Schistosoma mansoni is the causative agent of schistosomiasis, an endemic neglected tropical disease that affects the human population. Recently, newer versions of the genome and transcriptome have been published, with the Sanger Institute leading both the original publication of the genome as well as the further upgrade. However, little is known about the regulatory elements found in the genome, i.e. promoters. Identification of these elements is key for the understanding of mechanisms of regulation of gene expression in this parasitic helminth.
This project aims at identifying regulatory elements in the S. mansoni genomes, such as promoters actively regulating transcription.