GSE212127
Effect of alisertib and navitoclax on gene expression in B16 melanoma tumors
To investigate how tumor cells respond to alisertib and navitoclax single agents and combonation therapy in vivo, mice with melanoma were treated with these agents or vehicle-contol. RNAseq was used to investigate gene expression in tumors Overall design: C57Bl/6 mice were injected with B16 melanoma cells and treated with alisertib and navitoclax for 11 days