GSE133822
T cell and Monocyte Specific RNAseq Analysis in Septic and Non Septic Critically-Ill Patients and in Patients with Cancer
The purpose of this study was to determine the potential differential effect of sepsis on innate versus adaptive immune effector cells by examining RNA expression in monocyte/macrophages and CD4 and CD8 T cells respectively using next generation sequencing. Overall design: mRNA profiles of CD4, CD8 and CD14 cells were generated for sepsis, critically-ill non-septic, cancer patients and age-matched healthy controls using Illumina Hiseq 2500.