GSE109537
Protein arginine methyltransferase 6 drives endocrine resistance in breast cancer: ERa and NFkB signalling directly regulate PRMT6 expression
Gain- and Loss-of-function coupled with RNA-seq revealed that PRMT6 is involved in pathways drives breast carcinogenesis. Overall design: Mammary specific PRMT6 mice and PRMT6 knockdowned MCF-7 and MDA-231 cells were investigated using NEXTseq