GSE195510
FOXP1 Orchestrates Neurogenesis in Human Cortical Basal Progenitors
We report the application of single-molecule-based sequencing technology for high-throughput profiling of Forkhead Box P1, in human iPSC-derived forebrain organoids with and without FOXP1. We generated cell type-specific gene expression profiles of FOXP1 in progenitors and excitatory neurons of dorsal telencephalic lineage. Overall design: Examination of differentially expressed genes regulated by FOXP1 by comparing scRNA-seq results of WT organoids to FOXP1 KO organoids in different neural cell types