ena-STUDY-UNIVERSITAT POLITECNICA VALENCIA-01-08-2021-11:51:58:071-868
Whole metagenome sequences of cecum samples from a divergent selection study for intramuscular fat
Our study provides an exhaustive comparison of the microbiome core functionalities (captured by 3,936 microbial gene abundances) between hosts with divergent genotypes for intramuscular lipid deposition. After 10 generations of divergent selection for intramuscular fat in rabbits and 4.14 SD of selection response, we applied a novel combination of compositional and multivariate statistical techniques to identify 122 cecum microbial genes with differential abundances between the lines.This work elucidates that microbial biosynthesis lipopolysaccharides, peptidoglycans, lipoproteins, mucin components, and NADH reductases, amongst others, are influenced by the host genetic determination for lipid accretion in muscle.
Our study provides an exhaustive comparison of the microbiome core functionalities (captured by 3,936 microbial gene abundances) between hosts with divergent genotypes for intramuscular lipid deposition. After 10 generations of divergent selection for intramuscular fat in rabbits and 4.14 SD of selection response, we applied a novel combination of compositional and multivariate statistical techniques to identify 122 cecum microbial genes with differential abundances between the lines.This work elucidates that microbial biosynthesis lipopolysaccharides, peptidoglycans, lipoproteins, mucin components, and NADH reductases, amongst others, are influenced by the host genetic determination for lipid accretion in muscle.