GSE53499
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers
LED, a long non-coding RNA induced by Nutlin-3a, was found to activate enhancer RNAs, one of which was found in an intron of CDKN1A (p21). Overall design: Impact of expression of LED was assessed in MCF7 cells using RNAseq and GROseq. Chromatin binding of LED was assessed using ChIRPseq.