PRJNA700464
Genomic landscape of extraordinary responders in metastatic breast cancer
Extreme responders to anticancer therapy are rare among advanced breast cancer.Matched breast tumor tissue (somatic DNA) and blood samples (germline DNA) were collected from a total of 30 responders and 15 non-responders. Whole exome sequencing using Illumina HiSeq2500 was performed for all 45 patients (90 samples).