GSE121061
Genome wide RNA-seq of wild-type  iBMDMs upon HSV-1 infection.
Genome wide RNA-Seq screen was did to detect gene expression. We used  immortalized bone-marrow-derived macrophages cells that were uninfected or infected with HSV-1 for 6 hours to detect the expression levels of genes, and  we found that interferon stimulated genes were increased and some of genes that inhibit interferon production were decreased in HSV-1 infected iBMDMs, compared to wild-type iBMDMs. we choose some genes that are unknown about their functions on antiviral  innate immunity, and adress how they participate in antiviral  innate immunity. Overall design: Wild-type iBMDM were infected with HSV-1 for 6 hours, and then  genome wide RNA-Seq screen to detect the expression of genes.