GSE98299
Transcriptomic analysis of metastatic Sonic Hedgehog subgroup medulloblastomas
We report findings that illuminate a dynamic metastasis pathway in the common pediatric brain tumor medulloblastoma. Overall design: We examined the transcriptomes of medulloblastoma driven by ATOH1 in collaboration with aberrant Sonic Hedgehog (SHH) signaling, as well as those of medulloblastoma from Ptch1+/- animals.