GSE130229
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq)
We identified a novel cofactor of PRC2, expressed predominantly in the gonad, that limits PRC2 enzymatic activity by impeding the interaction between the core complex and the accessory subunits. Overall design: We characterized gene expression changes upon CXORF67 deletion in murine spermatogonia and oocytes.