GSE173371
LepR-positive cells from young and middle-aged C57B6 mice
We report the finding during intramembranous bone formation OPC proliferation is controlled by Notch signaling during the early repair phase, while differentiation is initiated by activation of canonical Wnt signaling during the later phase Overall design: Bulk RNAseq of LepR+ skeletal stem and progenitor cells from young (12-week), middle-aged (52-week), and middle-aged-treated mice treated with sodium salicylate