GSE191187
Cystatin M/E prevents osteolytic bone disease by inhibiting cathepsin-dependent stages of osteoclastogenesis
To further determine how CST6 regulates osteoclast differentiation. Overall design: RNA sequencing were performed on in vitro osteoclastogenesis on control macrophages (without RANKL sitimulation), RANKL treatment for 48h, RANKL plus CST6 treatment for 48h.