Klebsiella_pneumoniae_pan_Asian_genomic_surveillance_network_pilot_-sc-4833
Klebsiella_pneumoniae_pan_Asian_genomic_surveillance_network_pilot_
Klebsiella has been identified as a critical organism in the global spread of antimicrobial resistance, however genomic surveillance data is lacking in Asian countries. To address this gap we have established a group of hospitals in 15 Asian countries who will contribute Klebsiella pneumoniae clinical isolates for sequencing, with a view to establishing an ongoing collaborative network for genomic surveillance and research. In this pilot project we will sequence 960 isolates from 2015-2016. Key goals will be to identify the clonal groups present in each location; identify antimicrobial resistance and virulence determinants; and investigate the emergence and transmission of clinically important resistant and/or virulent clones in the regions.
Klebsiella pneumoniae has been identified as a critical organism in the global spread of antimicrobial resistance. Resistant and hypervirulent clones are increasingly recognised as a clinical problem in Asian countries, however little is known about the populations of bacteria circulating in the region. This project involves sequencing the genomes of 960 K. pneumoniae isolated from 15 countries during 2015-2016, to investigate the populations of clinically important resistant and/or virulent clones circulating in Asia.