ena-STUDY-CBMSO-30-03-2017-13:23:24:017-163
NGS sequencing of both whole DNA and mRNA was performed in Leishmania donovani lines selected by drug resistance.
In this study, NGS sequencing of both whole DNA and mRNA was performed in Leishmania donovani lines selected by their resistance against either antimony, anphotericin B, miltefosine or paromomycin. Chromosomal reorganizations and substantial changes in gene expression have been found to be associated with the different drug resistances.
In this study, NGS sequencing of both whole DNA and mRNA was performed in Leishmania donovani lines selected by their resistance against either antimony, anphotericin B, miltefosine or paromomycin. Chromosomal reorganizations and substantial changes in gene expression have been found to be associated with the different drug resistances.