GSE130638
ATAC-seq on parental and acquired resistant cells (AqR)
Parental and AqR cells were obtained. DNA was purified and submited for sequencing. Differential chromatin accessiblity was observed. AqR cells were derived from parental cells by adding inhibitor (CAY10566) every 3 days until cells became resistant (at about 3 weeks). Overall design: 1 parental cell in duplicate and 1 AqR cell in duplicate was submitted and analyzed.