PRJNA859811
AKT1 Transcriptomic Landscape in Breast Cancer Cells
The AKT1 was silenced using target-specific siRNA, or AKTs were inhibited using a widely used pan-AKT inhibitor VIII, followed by stimulating cells with or without epidermal growth factor (EGF, 120 ng/ml for 8 hr), and transcriptomic changes were assessed by RNA-sequencing.