GSE173824
scRNAseq studies of pMHCII-NP-induced Tet+ cells with different insulin-epitopes
SMARTseq2 scRNAseq analysis was performed on Tet+ and Tet- (Tconv) induced with 3 different insulin epitopes specificities (InsB12-20-CT-R1/IAg7, InsB13-21-R2/IAg7 and InsB10-23-CT_R3/IAg7) to study transcriptional reprogramming to different registers of the same epitope Overall design: Treatment of NOD mice with InsB12-20-CT-R1/IAg7, InsB13-21-R2/IAg7 and InsB10-23-CT_R3/IAg7 to induce Tet+ cells and perform scRNAseq studies