E-MTAB-11629
RNA-seq of human lung fibroblasts with and without TGF-beta1
Analysis of genes induced by TGF-beta1 in human lung fibroblasts. TGF-beta1 is essential for fibroblast -myofibroblast differentiation, which is a hallmark in the development of lung fibrosis. Newly identified  genes up- or down-regulated by TGF-beta1 in human lung fibroblasts may serve as pharmacological target for therapeutic options in patients with lung fibrosis.
Analysis of genes induced by TGF-beta1 in human lung fibroblasts. TGF-beta1 is essential for fibroblast -myofibroblast differentiation, which is a hallmark in the development of lung fibrosis. Newly identified  genes up- or down-regulated by TGF-beta1 in human lung fibroblasts may serve as pharmacological target for therapeutic options in patients with lung fibrosis.