GSE123532
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes
This study aims to investigate the profile and the role of lncRNAs in the IFN response initiated by TLR4 activation of primary human monocytes and their implication in the immune dysregulation present in SSc patients. Overall design: PolyA+ RNA profiles of human primary CD14+ monocytes freshly isolated or treated with LPS (100 ng/mL) for 90min or 4h were generated by deep sequencing using Illumina HiSeq 2000.