GSE131456
Linc1557 is critical for the differentiation initiation of embryonic stem cells by directly targeting LIF/STAT3 signaling pathway
This paper not only elucidated the critical function of linc1557 in mouse ESC differentiation initiation, but also clarified its specific mechanism by directly affecting the mRNA stability of Stat3. Overall design: The transcriptome of lncRNA knockdown and control mESCs were generarted by deep sequencing.