ena-STUDY-department of biology, university of padova-05-03-2014-10:01:35:729-48
Human corneas treated with 'cold plasma' (APCP) in presence or absence of NAC
Atmospheric pressure cold plasma (APCP) is a novel tool in medicine for tissue disinfection. It is  produced by a device that ionizes a flow of helium gas partially mixed with air. We recently reported that 2-minute of APCP application significantly reduce the microbial viability without evident damage on the ocular cells and tissues. To validate its use as antimicrobial for biomedical purposes such as ophthalmic applications, with this study we verified the functional changes in human corneas exposed to APCP by means of global gene expression analysis. To our knowledge, this is the first analysis of the effects of cold plasma on gene expression.
Atmospheric pressure cold plasma (APCP) is a novel tool in medicine for tissue disinfection. It is  produced by a device that ionizes a flow of helium gas partially mixed with air. We recently reported that 2-minute of APCP application significantly reduce the microbial viability without evident damage on the ocular cells and tissues. To validate its use as antimicrobial for biomedical purposes such as ophthalmic applications, with this study we verified the functional changes in human corneas exposed to APCP by means of global gene expression analysis. To our knowledge, this is the first analysis of the effects of cold plasma on gene expression.