GSE183246
Gene expression profiling of CD45+CD11b+F4/80high macrophages in MC38 tumor of WT mice injected with DMSO or picrotoxin
We characterized tumor-associated macrophages and found a pro-inflammatory signature of those cells in picrotoxin-treated mice compared to those in control mice (DMSO). Overall design: Examination one hundred of tumor-associated macrophages freshly sorted from tumor of WT mice injected with DMSO or picrotoxin on day 7 after tumor inoculation