PRJNA563921
Duplex sequencing mouse mtDNA (somatic tissues and oocytes)
Duplex sequencing of mtDNA from mouse somatic tissues (brain and skeletal muscle), single oocytes, and oocyte pools was performed to study the effect of aging on mtDNA substitution frequencies. Mice were from two independent predigrees, mothers were ~10 month old, and pups ~20 days old when samples were collected.