PRJNA862731
HTS data from the article "A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules"
We discovered a potent small molecule inhibitor (BRD7586) of SpCas9. BRD7586 inhibited the activity of SpCas9 at multiple genomic loci (EMX1, FANCF, VEGFA, eGFP). This dataset contains the FASTQ files obtained from next-generation sequencing at multiple genomic loci and concentrations of the BRD7586.