GSE203211
IS-Seq: a novel bioinformatics pipeline for integration sites analysis
IS-Seq pipeline is developed,and 4 data sets are used to compare different abundance estimation methods of this pipeline Overall design: HL60 cell line are transduced with a lentiviral vector, ddPCR is used to measure their average VCN, the gDNA from clone CL6 with average VCN=1 was diluted into gDNA from the transduced polyclonal HL60 bulk population at different relative contributions (100%, 75%, 50%, 10%, 1% and 0%)