GSE171000
Targeting circRNA TFRC in bladder cancer alleviates urinary tract infections by reducing erythroid progenitor cells
the same population of EPCs was detected in bladder cancer patients. The EPCs, whose function could be reversed via anti-CD71 treatment, were induced by the circRNA TFRC (circular RNA derived from the transferrin receptor mRNA; cTFRC) in bladder cancer exosomes. Overall design: severe immune deficiency in the context of Pseudomonas aeruginosa infection in the urethra of treatment-naïve bladder cancer-bearing mice.