DNMT3_KO_RNA_seq-sc-2013-03-18T14:32:38Z-2571
DNMT3_KO_RNA_seq
E7.5 embryos from Dnmt3a/3b conditional knock-out mice were isolated, and the epiblast and ectoplacental cone dissected. RNA was isolated from these tissues and mRNA sequencing libraries were generated using the ScriptSeq v2 kit.  This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
This study aims to identify genes that are misregulated as a consequence of DNA hypomethylation and that are important for correct embryonic development.