GSE158995
Total RNA sequencing in the hippocampus of wild type and APP/PS1 mice
Our study aimed to dissect differentially expressed circRNAs in the hippocampus of wild type and APP/PS1 mice and demonstrated the important role of circRNA in Alzheimer's disease. Overall design: We used deep RNA sequencing (RNA-seq) to examine the circRNA and mRNA in the hippocampus of APP/PS1 mice (which express APP695swe and PS1-dE9 mutations) and wild-type control mice at the 6-month-old stage.