GSE120314
Effects of LSD1 inhibitors on enhancer functions in T-ALL cells
We treated the T-ALL cell line MOLT4  with a novel LSD inhibitor and performed ChIP-seq analysis using anti-histoneH3K27ac antibody to assess the enhancer function. Overall design: We isolated fixed chromatin from MOLT4 cells treated with the LSD1 inhibitor S2157 and performed immunoprecipitation with anti-H3K27ac antibody, followed by deep sequencing.