f389f94b-c9cc-4291-8a28-6f3401946f34
iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage
The cause of esophageal atresia (EA) remains largely unknown. Differentiation to esophageal organoids of iPSCs derived from patients with EA reveals a dysregulation of SOX2 and NKX2.1, key factors in esophagus and trachea development.
The cause of esophageal atresia (EA) remains largely unknown. Differentiation to esophageal organoids of iPSCs derived from patients with EA reveals a dysregulation of SOX2 and NKX2.1, key factors in esophagus and trachea development.