GSE212201
MIF promotes cell invasion by LRP1-uPAR interaction in pancreatic cancer cells
To investigate the role of MIF in the regulation of malignant phenotype of pancreatic cancer , MIF gene has been knocked down by shRNA in PANC-1 cells. We then performed gene expression profiling analysis using data obtained from RNA-seq of shMIF (MIF knockdown) and shNTC (non-targeting control) cells at normoxia and hypoxia. Overall design: Comparative gene expression profiling analysis of RNA-seq data for shMIF-PANC-1 cells and its control shNTC-PANC-1 cells.