GSE114111
Mitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of leukemia cell line MOLM-13 cells
To explore the function of Mitochondrial Fission 1 (FIS1) in acute myeloid leukemia (AML), we used shRNA to knock down the expression of FIS1 in leukemia cell line MOLM-13 cells and performed RNA-seq experiments to profile transcriptional changes upon FIS1 depletion. Overall design: Expression of FIS1 is knocked down using two indepedent shRNA sequences in leukemia cell line MOLM-13 cells. Technical triplicates are performed. Total RNA is isolated and subjected to RNA-seq analysis.