DNMT3_KO_BS_seq-sc-2013-08-08T13:47:50Z-2740
DNMT3_KO_BS_seq
E7.5 embryos from Dnmt3a/3b conditional knock-out mice were isolated, and the epiblast and ectoplacental cone dissected. DNA was isolated from these tissues and BS-seq libraries were generated using the Post-Bisulphite Adaptor Tagging method.  This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
This study aims to identify genes that are misregulated as a consequence of DNA hypomethylation and that are important for correct embryonic development.