PRJNA802089
Study of the mechanism of action of a new antitubercular compound by transcriptomic approach
In this study, we explored the transcriptional response of Mycobacterium tuberculosis H37Rv upon exposure to a new antitubercular compound (MIC 0.25 ug/ml), by performing a differential expression analysis (RNA-Seq). We evaluated changes in gene expression levels in two independent experiments, by treating M. tuberculosis H37Rv cells with 2.5 ug/ml and 7.5 ug/ml of the new compound, respectively.