GSE137115
Developmental trajectory of pre-hematopoietic stem cell formation from endothelium (scATAC-seq data set)
To examine the cell and molecular transitions between endothelial (E), hemogenic endothelial (HE), and intra-arterial clusters (IAC) cells,  we profiled ~1700 cells from the caudal arteries (dorsal aorta, umbilical, vitelline) of embryonic day (E) 10.5 mouse embryos by single-cell  ATAC sequencing  (scATAC-Seq). We found extensive cis--regulatory landscape change during the endothelial to hematopoietic transition (EHT). Overall design: Single cell ATAC-seq profiles of cells involved in endothelial to hematopoietic transition (EHT) from mouse embryos at embryonic day 10.5