PRJNA723125
Assessing Reproducibility of Germline Variants Detected with Short-read Whole Genome Sequencing
Reproducible germline variant detection with whole genome sequencing (WGS) is vital for the implementation of precision medicine and is a complicated process in which each step affects variant call quality. To dissect the impacts of related factors, we sequenced triplicates of three DNA samples by three short-read sequencing platforms using three library kits in three labs