A Novel Method For Genome-wide Mapping of Human Tri-nucleotide Repeats
ZIP-seq: A Novel Method For Genome-wide Mapping of Human Tri-nucleotide Repeats At Single Base Resolution
We have developed a new method using the Next-generation sequencing tomap trinucleotide repeats at single base resolution. As a proof of evidence,wefirst apply on human embryonic stem cells. We have generated 32.3Gb single-end sequence data using the Illumina Hiseq 2000.Phred quality score are converted from Illumina to Sanger format and the last base is trimmed. No other filtering has been done prior to submission.