GSE159130
The human ß-globin enhancer LCR HS2 plays a role in forming a TAD by activating chromatin structure at neighboring CTCF sites
We propose that the HS2 has a role in forming a ß-globin TAD by activating neighboring CTCF sites and the role is beyond typical enhancer activity. Overall design: H3K27ac, H3K27me3 ChIP-seq was performed in control and LCR HS2 deletion cells.