GSE112226
Transcriptional profiling of intestinal changes following APC loss
Vil-CreERT2 was used to drive loss of APC (Adenomatous polyposis coli) in the murine intestinal epithelium.  4 days post induction, mice were sampled and 1cm of tissue from the proximal intestine was collected into RNA later.  This was compared to control (wild-type) intestine.  This analysis allows investigation of transcriptional changes following APC loss (and therefore activation of the WNT signalling pathway). Overall design: RNAseq Expression data from whole intestine comparing WT intestine vs VilCreER APCfl/fl