GSE161363
Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts
Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts Overall design: 9 scRNA-seq libraries of metastatic A549 cell lines. 4 of the libraries correspond to "TargetSite" libraries in which we extract lineage information for each cell. 5 of the libraries correspond to 3'-capture transcriptional libraries. In total, this repository includes: (1) Fastq files for each library; (2) processed "alleleTable" describing the lineage information for each TargetSite library; (3) "Character matrices" for lineage reconstruction; (4) reconstructed trees for each clone, in newick format; (5) scRNA-seq raw count matrices for the RNA-seq samples; and (5) meta data for each cell.