PRJNA412823
INSeq of Citrobacter freundii during bloodstream infection
The goal of this study was to identify bacterial genes that contribute to the survival and fitness of an opportunistic pathogen, Citrobacter freundii, during bacteremia. Bacterial isolates were obtained from University of Michigan Hospital System patients with Citrobacter bloodstream infections and the genomic sequences of each were determined de novo. From these isolates, a single C. freundii strain was selected for use in INSeq experiments to identify fitness genes in a murine model of bacteremia.