GSE113378
RNA aptamers specific for  IL4-treated MSC2 cell line
We performed an unsupervised, high-throughput (HT) sequencing-cell SELEX (systematic evolution of ligands by exponential enrichment) using the MDSC-derived cell line MSC2. Specifically untreated MSC2 and IL4 treated MSC2 were used as negative and positive selector respectively. Selection was started from a 5 ug of 40bp variable region linked to two constant region. Overall design: HT-SELEX across 11 cycles for the selection of RNA aptamers