GSE182980
Gene expression profiles of the prostates of prostate-specific Pten-/- mice
We reported the gene expression profiles of prostate dorsal-lateral-ventral glands of prostate-specific Pten-/- mice on AIN93M diet, 60%Kcal high-fat diet, and AIN93M diet containing 0.05% delta-tocotrienol at 20 weeks of age. Overall design: To study the effects of metabolic syndrome and delta-tocotrienol on the development of prostate cancer, we investigated the transcriptomes of the prostate of prostate-specific Pten-/- mice on AIN93M diet (control), 60% Kcal high-fat diet, and AIN93M diet containing 0.05% delta-tocotrienol starting at 6 weeks of age. Total RNA samples were extracted from prostate dorsal-lateral-ventral glands, separated under dissection microscope, collected from the mice at 20 weeks of age. RNA-sequencing was completed by BGI (US).