GSE109184
E2F6-mediated ceRNA and epigenetic silencing of miR-193a promote cancer stemness and immunoevasion in ovarian cancer
To investigate the knockdown effect of EZH2 and E2F6, RNA-sequencing (RNA-seq) was performed to analyze the genome-wide changes by the knockdown of EZH2 or E2F6 in CP70 ovarian cancer cells. Overall design: CP70 ovarian cancer cells were infected with pLKO TRC005 (vector control) or pLKO TRC005 shE2F6 (treatment) or pLKO.1-puro shEZH2(treatment).