GSE161623
The effect of NEIL3 on CA1 DNA methylation
CA1-specific brain tissue from the hippocampal formation was isolated at baseline (homecage condition). DNA was extracted and sequenced after bisulfite conversion to determine differentially methylated regions Overall design: Wildtype (C57Bl6) and NEIL3-deficient (Neil3-/-, C57Bl6-background) were used. 3 wildtype and 3 mutant animals were included. Animals were exposed to the same housing conditions, food ad libitum and handled by the same experimenters.