GSE163088
Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation
We report the application for high-throughput profiling of transcriptome, chromatin-associated proteins and histone-modifications on a genome-wide level in iPSC-derived family control astrocytes vs LFS (Li-Fraumeni Syndrome) patient astrocytes. Overall design: RNA-seq, ChIP-seq, eCLIP-seq and m6Aseq are used to profile LFS patient derived astrocytes