PRJNA686835
Human gut microbiota Raw sequence reads from medication-naive individuals who are lean or abdominally obese subjects with and without T2D
Numerous studies have revealed the association of gut microbiota to the development of two human metabolic disorders, obesity and type 2 diabetes (T2D). Medical research has found a positive correlation between the two diseases, and previous metagenomic studies have reported potential metagenomic markers linked with them. However, few metagenomic studies have been designed to investigate two related diseases interactively. Our objective here is to investigate how the gut microbiota contribute to the development and the differentiation of people into different metabolic status of obesity and T2D, by looking into 182 subjects from lean individuals with normal glucose tolerance (NL), abdominally obese individuals with normal glucose tolerance (NAO), lean individuals with T2D (TL) and abdominally obese individuals with T2D (TAO).