PRJNA715076
T cell receptor gamma and delta chain next generation sequencing on TCRgamma/delta lymphoproliferative disorders
A deep-analysis (TCR-NGS) in a cohort of 11 patients affected by Tgamma/delta neoplasm (pt1-pt2 HSTCL, pt3-pt11 T-LGLL) compared to 23 healthy controls showed that patients' dominant gamma and delta clonotypes were mainly public and exhibit different V-(D)-J usage between patients with symptomatic and indolent disease.