Identification_of_driver_mutations_in_Tel_AML1_driven_ALL-sc-2011-01-12
Identification_of_driver_mutations_in_Tel_AML1_driven_ALL
Here we have sequenced the exome of progenitor B cell tumours taken from mice that express the Tel-AML1 fusion oncogene. . This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
We have developed a mouse model of acute lymphoblastic leukemia driven by the Tel-AML fusion gene. In this experiment we will sequence the exome of tumours taken from this model to identify genes that co-operate with Tel-AML1 in ALL development.