PRJNA827678
Insulin resistance, dyslipidemia, metabolite profile and gut microbiome status in p47phox knockout mice
Involvement of NOX-dependent oxidative stress in the pathophysiology of metabolic disorders as well as in the maintenance of metabolic homeostasis has been demonstrated. In the present study we evaluated the host metabolic profile and gut microbiota in p47phox-/- and WT mice fed on chow diet, to assess the role of microbiome in glucose intolerance and dyslipidemia under altered oxidative stress condition.