GSE194082
Transforming Growth Factor-ß (TGFß) Prevents Hypertension-Induced Aortic Dissection in Adult Mice via Extracellular Matrix Production (Bulk KO vs. WT SMC)
We report bulk RNA-seq data of Myh11 lineage marked smooth muscle cells (SMCs) from murine aortas at 1 week after conditional disruption of TGFß signaling versus controls Overall design: Thoracic aortas were procured from tamoxifen-treated, 12-week-old  Myh11-CreERT2.mT/mG (designated as GFPiSMC or simply WT) or Tgfbr1f/f.Tgfbr2f/f.Myh11-CreERT2.mT/mG (designated as Tgfbr1/2iSMCKO or simply KO) mice, GFP+ SMCs were isolated after cryophilic enzyme digestion of thoracic aorta segments, and bulk RNA-seq analysis was performed