GSE118287
Transcriptome analysis for modulating ubiquitin siganlling in the amniote embryo via phosphoregulation of the E2 enzyme UBE2D3
Purpose: Understanding the transcriptional effects of a gain of function mutation of the E2 enzyme UBE2D3 in embryonic stem cells Methods: mRNA profiles of wt E14 ES cells and UBE2D3 Ser138Ala mutant ES cells were generated Overall design: 6 samples examined: 3 WT E14 ES cells and 3 S138A mutant E14 ES cells