GSE117603
DROSHA complementation experiments using small RNA sequencing
DROSHA complementation experiments were performed to check whether dsRBD of DROSHA recognizes the lower stem of pri-miRNAs and affects miRNA biogenesis. Overall design: Mature miRNAs were sequenced from HCT116 DROSHA-null cells which had been transfected with wild-type or mutant DROSHA plasmids.