GSE160121
Alterations in liver and epididymal white adipose tissue (eWAT) gene expression in mice with a global ablation of the NcoR? splice isoform of the corepressor Ncor1
A knockin mouse line created that contains a point mutation that elminates the requisite GT in the 5' donor site of each of the NCoR? splice variants, thus preventing splicing at that site and forcing splicing of the reciprocal NcoRd splice variant. Overall design: Adult WT & NCoR-omega KO male C57BL/6N mice fed HF (60% Kcal fat) or LF (10%) diet for 10 weeks