PRJNA540919
Homo sapiens Raw sequence reads
Early diagnosis of colon cancer (CC) is clinically important, as it can significantly improve patients' survival rate and quality of life. In this work, plasma sEVs were derived from 15 early stage (TisN0M0) CC patients and 10 normal controls (NC). RNA sequencing identified a total number of 95 sEVs miRNA with differential expression between CC and NC, most of which (60/95) was in well accordance with tissue results in the Cancer Genome Atlas (TCGA) dataset.