GSE185793
Comparative bulk RNAseq analysis of cultured single-clone WT (P23) and p53-deleted (cKO, P28 and P4M) skeletal cells in bone marrow
we revealed the cellular mechanisms underlying the tumorigenicity of skeletal cells. Overall design: tdTomato+ cells were cultured for 8 passages from Fgfr3creER; R26R-tdTomato (WT, P23) and Fgfr3creER; Trp53fl/fl; R26R-tdTomato (cKO, P28 and P4M) femur bone marrow. Tamoxifen was injected at P21. cDNA were sequenced by Illumina NovaSeq 6000