GSE132612
Paternal overdiet drives intergenerational transmission of metabolic disorders through sperm epigenetic alteration [MeDIP-Seq]
We using a mouse model of paternal famine to simulate famine, our data show that paternal famine increases the susceptibility to metabolic disease in offspring through gametic epigenetic alterations. Overall design: Sperm DNA profiles of 12 week old control male F0 and Famine male F0 mice were generated by deep sequencing