PRJNA451252
An enhanced CRISPR repressor for targeted genetic screens
Sequence data from CRISPR repressor gRNA library screens where dCas9, dCas9-KRAB, and dCas9-KRAB-MeCP2 were used. dCas9-KRAB-MeCP2 outperforms previous dCas9 repressors in identifying genes essential for cell survival and detecting genetic interactions between genes.