ena-STUDY-HPA-05-11-2014-17:01:30:874-681
Salmonella Typhi H58 antibiotic resistance island
Here, we report the use of the MinION to resolve the structure of a composite transposon, encoding multidrug resistance, in Salmonella Typhi Haplotype 58 - a multidrug resistant strain that has undergone global expansion. MinION data from a single 18-hour run was used to scaffold Illumina data and identify the chromosomal insertion site and structure of the island.
Here, we report the use of the MinION to resolve the structure of a composite transposon, encoding multidrug resistance, in Salmonella Typhi Haplotype 58 - a multidrug resistant strain that has undergone global expansion. MinION data from a single 18-hour run was used to scaffold Illumina data and identify the chromosomal insertion site and structure of the island.