PRJNA665113
Mus musculus strain:C57/B6J Genome sequencing and assembly
Nonalcoholic steatohepatitis (NASH) and associated liver fibrosis have limited therapy options. Here we report a novel adiponectin-based dual agonist for adiponectin receptors 1 and 2 with a longer half-life, and show that it ameliorates NASH and liver fibrosis in mouse models.