GSE130313
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis
Epigenetic activation of an enhancer for TGFB2 locks SSc patient fibroblasts into a pro-fibrotic synthetic state through mechanisms dependent on NF-kB and BRD4. Overall design: Examination of chromatin accessibility and transcriptome of healthy control and patient fibroblasts