PRJNA839584
microbial diversity on Esophageal squamous cell carcinoma
Patients receiving neoadjuvant chemotherapy combined with immunotherapy were divided into responders and nonresponders by imaging methods after 2 cycles of treatment. All patients receiving neoadjuvant therapy received surgical treatment, and we collected intraoperative cancer and paracancer tissues of responders and nonresponders, and conducted 16S rRNA sequencing to analyze the relationship between tumor flora and patient efficacy.