GSE163035
RNA sequencing of triple mutant MTOs in suboptimal growth conditions
We profiled mouse tumor organoids (MTOs) in complete stem cell media and in medium without EGF or in the presence of TGFb Overall design: Comparison of 2 different MTOs per each genotype (2x AKP + 2x APT). AKP MTOs (54 and 220) were cultured in full stem cells medium (+6) or without LY/+TGFb. APT MTOs (100 and 101) were cultured in +6 and without EGF.