GSE130443
Progenitor-Derived Human Endothelial Cells Evade Alloimmunity by CRISPR/Cas9-Mediated Complete Ablation of MHC Expression
Purpose: To compare human progenitor cell-derived endothelial cells ablated of MHC molecules to endothelial cells transduced with control vector after IFN-y treatment Overall design: Comparison of interferon-gamma treated cord-blood endothelial cells with CRISPR/Cas9 targeting of B2-Microglobulin and CIITA