GSE193904
iCLIP of FLAG-PURA overexpression with anti-PURA12D11 antibody in HeLa cells
The protein PURA binds to DNA and RNA and has been suggested to be implicated in different cellular functions. Here, we show that PURA predominantly resides in the cytoplasm, where it binds to a large set of transcripts. Overall design: We performed PURA iCLIP with a PURA specific Antibody in HeLa cells with a stable FLAG-PURA overexpression in four biological replicates.