GSE40668
An atlas of in vivo transcribed enhancers in human primary cells
Enhancers are powerful regulatory regions, important for development and the maintenance of differentiated cells and tissues. Here, we generate global maps for two enhancer-associated histone marks, H3K4me1 and H3K27ac for a number of major human blood cell types. This data was generated to show that capped RNAs transcribed bidirectionally can identify known and novel enhancers in vivo. Overall design: ChIP-seq of 2 histone marks in human blood monocytes, CD19+ B cells, CD8+ T cells, CD4+CD25-CD45RA+ naive T cells, & NK cells