GSE201057
satmut_utils: a simulation and variant calling package for multiplexed assays of variant effect
We use stable expression of a cystathionine-beta synthase (CBS) variant library in HEK293T cells to identify CBS coding sequence variants that alter mRNA abundance Overall design: Amplicon and rapid amplification of cDNA ends (RACE)-like targeted library preparation chemistries were used to assay variant abundance in total RNA and gDNA by Next-Generation Sequencing