PRJNA526881
Conservation and Global Distribution of noncanonical antigens in Enterotoxigenic Escherichia coli
A geographically diverse subset of Enterotoxigenic Escherichia coli (ETEC), also expressing different colonization factors, were sequenced to determine the genetic conservation of non-canonical ETEC vaccine antigens, EtpA and EatA. The function of the most divergent sequences were tested to determine any functional consequences of observed genomic diversity.