PRJNA789458
Whole genome DNA methylation profiling of mouse nucleus accumbens Drd2 medium spiny neurons by using two independent library preparation methods
Drd2 medium spiny neurons in nucleus accumbens of Drd2-GFP mice were collected by fluorescence-activated cell sorting. Genomic DNA samples were isolated and processed parallelly for whole-genome methylation profiling by two library preparation protocols. One of the protocols is bisulfite sequencing using Swift Accel-NGS Methyl-Seq DNA Library Kit, the other is using NEBNext Enzymatic Methyl-seq Kit.