PRJNA830870
SHAPE-MaP of SARS-Cov-2 IVT 5' end transcripts
The goal of this experiment was to determine the secondary structure of in vitro transcript fragments of SARS-Cov-2 5' end using chemical probing. Additionally, mutations were made at the TRS site to determine if alternative conformations are detected as well as rescue mutations to see if the structure was restored.