GSE161508
Clonal expansion of CD8+ T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI.
We show that an effective GvL is associated with a substantial drop of CD8+ TRB diversity and a concomitant expansion of dominant clones. Overall design: TRB sequencing of sorted CD8+ T cells comparing leukemia patients with and without GvL effect after therapeutic DLI; SupplementalTables.docx containing sTable 1 "Patient samples" and sTable2 "Response to DLI"