GSE211017
Cxxc finger protein 1 maintains homeostasis and function of intestinal group 3 innate lymphoid cells with aging [Cxxc1 KO CUT&TAG]
To investigate the role of Cxxc1 in the regulation of ILC3 development and function, we carry out cleavage under targets and tagmentation (CUT&Tag) to characterize the genome-wide profiles of the H3K4me3 modification  on Cxxc1flox/floxRorccre and Cxxc1flox/flox ILC3s. Overall design: ILC3s from Cxxc1flox/floxRorccre and Cxxc1flox/flox  mice were isolated from the small intestine and analyzed by cleavage under targets and tagmentation (CUT&Tag).