Study
Evaluation of genomic high-throughput sequencing data generated on Illumina HiSeq and Genome Analyzer systems
Background: The generation and analysis of high-throughput sequencing data is becoming a major component of many studies in molecular biology and medical research. Illumina's Genome Analyzer (GA) and HiSeq instruments are currently the most widely used sequencing devices. Here, we comprehensively evaluate properties of genomic HiSeq and GAIIx data derived from two plant genomes and one virus (read length 95-150 bases): Enterobacteria phage phiX174, Arabidopsis thaliana Columbia (Col-0), and Beta vulgaris subsp. vulgaris (KWS2320).<p> 