GSE108484
Transcriptome analysis of Chrdl1-treated RGCs
Chrdl1 treatment promotes formation of synapses and GluA2-AMPAR recruitment in Retinal ganglion cell (RGC) cultures. Analysis of the transcriptome of RGCs with or without Chrdl1 treatment let us determine potential alterations in the expression of genes related to BMP signaling, or genes involved in excitatory synaptogenesis and AMPAR trafficking. Overall design: RNA was isolated from RGC cultures treated for 12 hours with 1ug/ml Chrdl1, and compared to RNA isolated from buffer-treated (vehicle) RGCs as a control.