GSE115618
Comparison of global gene expression in homeostatic and regenerating endothelium of the adult mouse aorta
We report the global transcript levels in an endothelial-enriched cell fraction from homeostatic and regenerating mouse aorta. These data provide insight into the molecular regulation of endothelial lining regenerating inside a large artery. Overall design: Total RNA-seq comparing global gene expression in 4 conditions: 1) uninjured aorta segment 48 hours post-wound 2) endothelial fraction regenerating aorta 3 hours post-wound 3) endothelial fraction regenerating aorta 48 hours post-wound 4) tissue fraction of regenerating aorta 48 hours post-wound