GSE120858
MYCN knock-down leads to DNA-repair deficiency in human neuroblastoma (RNA-Seq)
We knock down MYCN in human neuroblastoma cell line by RNAi. MYCN knock-down caused global epigenome change, including nucleosome gain on key DNA-repair genes and promoter H3K9ac down regulation. Overall design: mRNA gene expression profiles of ctrl/MYCN-kd in human neuroblastoma cell line BE2C..