ena-STUDY-National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthcare of the Russian Federation-03-08-2020-10:21:31:773-2099
Premature atherosclerosis in a patient with hypertriglyceridemia
We present a case of a 40-year-old male with premature atherosclerosis, presenting with both eruptive and tendinous xanthomas, which could imply increase in both low-density lipoprotein (LDL) and triglyceride (TG) levels. However, his LDL was 2.08 mmol/l, TG – 11.8 mmol/l on rosuvastatin 20 mg. Genetic evaluation was performed using a custom panel consisting of 25 genes and 280 SNPs responsible for lipid metabolism to reveal the genetic backgroun of this condition.
We present a case of a 40-year-old male with premature atherosclerosis, presenting with both eruptive and tendinous xanthomas, which could imply increase in both low-density lipoprotein (LDL) and triglyceride (TG) levels. However, his LDL was 2.08 mmol/l, TG – 11.8 mmol/l on rosuvastatin 20 mg. Genetic evaluation was performed using a custom panel consisting of 25 genes and 280 SNPs responsible for lipid metabolism to reveal the genetic backgroun of this condition.