GSE117177
Inter-tumoral heterogeneity in SCLC is influenced by the cell-type of origin
We describe cell-of-origin as an important influence on suscebtability to changes in chromatin accessibility by Nfib Overall design: We performed ATAC-seq on primary tumors and metastasis from SCLC mouse model (Rb/p53/p130/mTmG) transduced by Ad-CMV-Cre or Ad-CGRP-Cre