DRP007711
Functional analysis of MeCP2 in astrocyte
Rett syndrome (RTT) is a severe neurodevelopmental disorder affecting almost exclusively females. RTT is caused by sporadic mutations in the X- linked transcriptional regulator methyl-CpG binding protein 2 (MECP2) gene. Recent studies show that MeCP2 is expressed and functions in not only neuron but also glial cells. Our goal is to understand the role of MeCP2 in astrocyte.
Rett syndrome (RTT) is a severe neurodevelopmental disorder affecting almost exclusively females. RTT is caused by sporadic mutations in the X- linked transcriptional regulator methyl-CpG binding protein 2 (MECP2) gene. Recent studies show that MeCP2 is expressed and functions in not only neuron but also glial cells. Our goal is to understand the role of MeCP2 in astrocyte.