GSE208408
Effect of TMEM43 overexpression on gene expression in adult zebrafish hearts
To determine transcriptional changes caused by the overexpression of wild-type and mutant TMEM43 and to gain insights into the mechanisms responsible for the phenotype of arrhythmogenic cardiomyopathy We performed RNA-sequencing in adult zebrafish hearts Overall design: Comparative gene expression profiling analysis of RNA-seq data for adult non-transgenic (NTG), wild-type TMEM43 (TMEM43-WT), p.P111L mutant TMEM43 (TMEM43-p.P111L) and p.S358L mutant TMEM43 zebrafish hearts