GSE159637
RNA sequencing reveals the transcriptomic profile of human neuroblastoma SK-N-BE(2) cell line after MCM6 interfered by small interfering RNA
Minichromosome maintenance complex component 6 (MCM6), as an important replication permission factor, is involved in the pathogenesis of various tumors. we studied the expression of MCM6 in neuroblastoma and its influence on tumor characteristics and prognosis, and we found MCM6 has significant effect on tumor growth promotion. To investigate the underlying mechanism that MCM6 in neuroblastoma, we compared the transcriptomes of siRNA interfered MCM6 and negative control neuroblastoma cells. Overall design: 6 samples of human neuroblastoma cells were divided into two groups: MCM6 interference group and control group, with 3 replicates in each group.