PRJNA716814
ATACseq of AXIN2-/+ hepatocytes and AXIN2+ intestinal stem cells (ISCs) and LGR4/5KO hepatocytes
Previous studies have shown low expression of metabolic genes in ISCs and low expression of cell cycle genes in hepatocytes (HEP). Here, we perform ATACseq to exam differential usage of WNT signaling in regulating cell proliferation and metabolism between liver and small intestine in chromatin based mechanisms.