phs000257_56
Metagenomic Analysis of the Structure and Function of the Human Gut Microbiota in Crohn''s Disease
This study aims to unravel the contribution of the bacteria that normally inhabit the human gastrointestinal tract to Crohn''s disease by using a multidisciplinary approach to study changes in the structure and function of gut microbial communities in three sets of patient cohorts who have Crohn''s disease. These results will be compared with those obtained from the study of healthy individuals and have the potential to identify new biomarkers of disease severity, location, and progression.