GSE188772
Regional heterogeneity of glioblastoma upon single-cell RNA sequencing
Using spontaneous mouse GBM model, regional dissection of cortical margin, callosal margin, and tumor center was done for single-cell RNA sequencing to investigate molecular characteristics of marginal cancer cells. Overall design: Cancer cells were sorted from cortex, corpus callosum, and tumor center respectively, then single-cell RNA libraries were made independently.