PRJNA422871
Role of tsrA in V cholerae
H-NS has been known to repress virulence factor expression in enterics, a function that is often modulated by interaction partners such as HHA. As no such partners were previously known in V Cholerae, we identified and validated a putative interaction partner, tsrA, that appears to control H-NS binding to horizontally-acquired genomic islands that house many virulence genes.