GSE126574
The Branched-Chain Amino Acid Transporter CD98 Heavy Chain Facilitates the Development of Colonic Macrophages Associated with Decreased Apoptosis in Macrophage Progenitors
We performed a single-cell transcriptome analysis of colon monocytes and macrophages from corn oil treated CD98?CX3CR1 mice and tamoxifen induced conditional Cd98 KO (CD98?CX3CR1) mice. Overall design: Lamina propria cells positive for Cd11b and positive for Ccr2 or Cd64 were sorted from 4 control (corn oil) mice and 4 tamoxifen induced Cd98 KO mice and used for single cell RNA Seq (10x genomics platform)