ena-STUDY-INSTITUTO NACIONAL DE SALUD-27-09-2018-16:34:36:735-213
Since 1993, Mexico has been part of the SIREVA network, a laboratory-based surveillance Latin-American group, coordinated by the Pan American Health Organization (PAHO) that monitors pneumococcal infection. Twenty years later, the network changes its name to GIVEBPVac to include other vaccine preventable bacteria.  This network is particularly involved in the dynamics of pneumococcal lineages and serotypes before and after introduction of new conjugated vaccines.
S. pneumoniae serotype 2 has been reported as a cause of meningitis, particularly affecting younger children in low and middle-income countries. The aim of the study is to describe in detail serotype 2 pneumococcal isolates causing meningitis based on a 23 year surveillance in Mexico. Genotypic relatedness of the strains will be analyzed by PFGE and MLST. The genomes of particular strains will be analyzed and virulence and antimicrobial resistance strains will be detected.
S. pneumoniae serotype 2 has been reported as a cause of meningitis, particularly affecting younger children in low and middle-income countries. The aim of the study is to describe in detail serotype 2 pneumococcal isolates causing meningitis based on a 23 year surveillance in Mexico. Genotypic relatedness of the strains will be analyzed by PFGE and MLST. The genomes of particular strains will be analyzed and virulence and antimicrobial resistance strains will be detected.