GSE161370
A223 bintrafusp alfa non-responders and responders
Mice bearing murine A223 SCC tumors were treated with bintrafusp alfa, targeting both TGF-beta and PD-L1, then processed for single-cell sequencing to identify cell population signaling changes that characterize responders to therapy. Overall design: Murine A223 tumors from two non-responders and two responders to bintrafusp alfa were analyzed.