GSE211374
RNA data of NCI-H446 tumours treated with ERY974 and/or paclitaxel in huNOG mice.
We found that ERY974 shows only moderate antitumor efficacy in NCI-H446 non-inflamed tumor in huNOG mice. We also observed that ERY974 + paclitaxel increases antitumour efficacy in non-inflamed NCI-H446 tumours. To identify a mechanism of combination effect, we compared RNA expression of NCI-H446 tumors treated with ERY974, cisplatin, or combination. Overall design: Comparative gene expression profiling analysis of RNA-seq data for tumors treated with ERY974, paclitaxel, or combination in huNOG model.