GSE108593
Hyaluronic Acid Synthase-2 (HAS2) overexpression and deficiency effect on hepatic stellate cells
Analysis of hepatic stellate cells (HSCs) isoltaed from ASMA-HAS2 transgenic and HSC-specific Has2 knockout mice. HAS2 synthesized hyaluronic acid, one of major extracellular matrix. Results provide insight into the role of HAS2 in hepatic stellate cells. Overall design: Hepatic stellate cell mRNA profiles of ASMA-HAS2 transgenic (Tg) and Has2 f/f Lrat-cre (KO) mice were generated by deep sequencing, in triplicate, using BGISEQ-500