PRJNA723120
different gene expression in  efferent ductules of miR-34/449 dKO mice
We tested the role and mechanism of the miR-34,449 family in the regulation of multiciliogenesis in EDs using an miR-34b,c; miR-449double knockout (dKO) mouse model. RNA-seq analyses revealed that the aberrantdevelopment ofMCCs in the EDs of dKO micewas associated with the upregulation of genes involved in cell cycle control.