GSE121424
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [ChIP-Seq]
We characterized the changes in histone modifications as well as the localization of LSD1 and GFI1B for both wt SET-2 and drug-resistant SET-2 LSD1 (Leu659_Asn660insArg) treated with GSK-LSD1 Overall design: ChIP-seq for histone modifications as well as LSD1 and GFI1B in wt SET-2 and drug-resistant SET-2 LSD1 (Leu659_Asn660insArg) upon treatment with DMSO or GSK-LSD1