PRJNA483206
PND28 mouse pup fecal microbiota from wild-type or double mutant (Ryr1(T4826I) knockin/FMR1-CGG) treated with PCB (0, 0.1, 1 or 6 mg/kg) during gestation (GD14). Targeted loci
PND28 mouse pup fecal microbiota from wild-type or double mutant (Ryr1(T4826I) knockin/FMR1-CGG) treated with PCB (0, 0.1, 1 or 6 mg/kg) during gestation (GD14). We wish to test whether developmental PCB exposure will impact the developing gastrointestinal tract and the composition of the microbiota and if mice with a genetic predisposition are more susceptible to dybiosis and functional deficits. Targeted loci- 16S amplicon sequencing