GSE134985
RNA-sequencing of human peripheral blood mononuclear cells from Tanzanian children
Total RNA sequencing of peripheral blood mononuclear cells (PBMC) from Tanzanian children from the Phase 3 trial of the RTS,S (Mosquirix) vaccine (ClinicalTrials.gov NCT00866619). At baseline (B0) children were between 5-17 months of age at baseline (B0), and were 32 months older at B32. Overall design: The RNA-sequencing data compliments a much larger immune-phenotyping study. Where there was sufficient cells remaining after flow-cytometry experiments, cells were stored in RNA-later. Samples from time-points B0 (n=21) and B32 (n=9) were then sequenced to determine how the blood transcriptome changes over time. Three participants had samples were sequenced at both B0 and B32.