GSE126166
Chromatin profiling in HT22 hippocampal cells
We conducted genome-wide analysis of KMT2D binding sites in a hippocampal cell line to define KMT2D-dependent functions in neuronal context Overall design: ChIP-seq in wild-type HT22 cells and HT22 cells with CRISPR-Cas9 mediated deletion of the KMT2D enzymatic SET methyltransferase domain, comparing KMT2D-pulldown and input controls