GSE167704
Ribosome profiling experiments of LRRK2 mouse models
G2019S mutaion of LRRK2 is known to increase mRNA translation. We perform ribosome profiling to study defective translation in mammalian LRRK2 models. We used G2019S LRRK2 transgenic mice, G2019S/D1994A LRRK2 transgenic mice, LRRK2 knockout mice. Overall design: Mouse: 3 months old. Biological replicates were generated for mouse experiments.