GSE201148
Effect of cancer cell knockdown of EphB4 in a Moc2 tumor model
To investigate the functional significance of EphB4, we generated cancer cell-specific knockdown of EphB4 in a head and neck cancer cell line, Moc2, using shRNA approach. These cells along with the controls were orthotopically implanted in a C57BL/6 murine model and tumors for harvested for RNA-seq analysis Overall design: To compare the gene expression profiling of RNA-Seq data for Moc2 control sh, and Moc2 EphB4 sh tumors