PRJNA827104
Effects of obeticholic acid on ileum microflora in BDL rats
To investigate the effect of FXR activation, bile-duct-ligation rats were treated with obeticholic acid (OCA [5 mg/kg/day]) or vehicle (0.5% methyl cellulose) per oral gavage for 14 days.Gut Microbiome was determined by 16S rDNA MiSeq sequencing.