PRJNA564210
Akkermansia muciniphila improved arginine metabolism and removed multi-drug resistance plasmid NDM-1 in mice gut
A carbapenem-resistant E.coli (CRE) isolated recovered from a patient in China. Following different antibiotic-treatment disruption the gastrointestinal microbiota that result in distinct microbiota changes and lead to different clearance of CRE. The probiotic microbiota Akkermansia muciniphila correlated with resistance to CRE colonization. Of these, arginine metabolism genes correlated significantly with clearance of CRE.