PRJNA684602
WGS of Plasmodium falciparum selected with AcAS inhibitors
These Plasmodium falciparum samples have been in vitro selected with antimalarial compounds MMV019721 and MMV084978 as part of a drug target identification study in the MalDA Consortium. Based on these selections and follow-up validation , both compounds have been classified as inhibitors of acetyl co-enzyme A synthetase (PfAcAS).