GSE121923
Genome-wide analysis of chromatin profile in astrocytes isolated from EAE mice transduced with astrocyte-specific Xbp1-targeting or non-targeting lentiviruses.
We report XBP1 activation and regulation of pro-inflammatory gene expression in astrocytes during EAE. Overall design: Mice transduced with non-targeting (n=4) or Xbp1-targeting (n=3) lentiviruses. EAE induced in mice.