GSE131183
Comparison of Ly6c high splenic monocytes from IL-17A/F-deficient versus control mice
The goal of this study was to compare transcriptional changes, on the single cell level, in splenic monocytes evoked by global IL-17A/F deficiency Overall design: CD90-CD19-CD11b+Ly6c+(high) monocytes were FACS-sorted from spleens of control and IL-17A/F-deficient mice, single cells were captured and processed using the BD Rhapsody platform, and messenger RNA profiles of 397 genes (BD Rhapsody Immune Response Panel Mm) were generated by deep sequencing using Illumina HiSeq2500