GSE131005
RNA-seq on parental and acquired resistant cells (AqR)
Parental and AqR cells were obtained at diferent time-points (Day1 and Day 18). Total RNA was extracted and submitted for RNA-seq. Differential expression was observed between parental and AqR cells. AqR cells were derived from parental cells by adding inhibitor (CAY10566) every 3 days until cells became resistant (at about 3 weeks). Overall design: 2 parental cell lines in duplicate (G68 D1 A,B and G82 D1 A,B) and 2 AqR cell lines in duplicate (G68 D18 A,B and G82 D18 A,B) were submitted and analyzed.