Protective Effects of 20-Hydroxyecdysone on Diabetic Liver Injury: Involvement of miR-34c-5p/GREM2 Axis and PI3K/Akt Pathway
This project aimed to evaluate the therapeutic effects of 20-HE on diabetic liver injury (DLI) and elucidate its underlying mechanisms. DLI animal model was performed in accordance to the classic method using STZ. Liver tissue samples (n=3) from the control, model, and 20-HE (6 mg/Kg) groups were processed for RNA sequencing by the Novogene Bioinformatics Institute (Novogene, Beijing, China).