Nobiletin ameliorates liver lipid accumulation under continuous light conditions by modulating  the AMPK/ACC lipid metabolism pathway
Sustained light conditions in polar environments have been reported to have effects on human metabolism. Liver, the most central metabolic organ of the body, is not well characterized under sustained light conditions. The citrus flavonoid Nobiletin (Nob) has been shown to have an ameliorative effect on cardiovascular and metabolic health. I, therefore, investigated the effect of Nobiletin on hepatic lipid metabolism under sustained light conditions in a polar environment.