Transcriptional response of hamster intestine to SARS-CoV-2 and hookworm co-infection
This project demonstrates the host transcriptional response to SARS-CoV-2 during hookworm infection, using hamsters as an animal model for infection. RNA-seq transcriptome samples are used to quantify and characterize acute host transcriptomic lung and intestine responses to infection, and interrogate global transcriptional profiles among four groups: naive (uninfected), hookworm-infected only, virus-infected only and co-infected samples.