Fecal sequencing in murine colitis
The gut microbiota and diet are important factors in the occurrence and development of ulcerative colitis (UC). 5-aminosalicylic acid (5-ASA) has a negative regulatory effect on UC, and the potential impact of a high-fat diet (HFD) on intestinal microbiota dysbiosis regulation is still unclear. We performed differential gut microbiota analysis and metabolomic analysis of dextran sulfate sodium (DSS)-treated mice fed an HFD.