Transcriptomic analysis of chemotherapy-induced HUVEC injury
BackgroundPremature ovarian insufficiency (POI) is a clinically refractory reproductive system disorder. Our previous studies demonstrated that the traditional Chinese herbal formula Siwu Tang may ameliorate POI in animal models by improving ovarian angiogenesis, yet the underlying mechanisms remain unclear.ObjectivesTo explore the mechanisms of the traditional Chinese medicine formula SWT on human umbilical vein endothelial cells and animal models of POI. By studying its mechanisms, the research hopes to reveal the connotation of nourishing blood and activating blood circulation in Chinese medicine.