Comparative Transcriptomic Raw Sequencing Data of Indotyphlops braminus
The Brahminy blindsnake (Indotyphlops braminus) is the only known obligately parthenogenetic and triploid snake, offering a unique model for studying polyploidy and asexual reproduction. Despite its biological significance, the transcriptomic mechanisms underlying its tissue-specific functions remain largely unexplored. In this study, we sequenced and compared the transcriptomes of five tissues (ovary, eye, heart, liver, and skin) using de novo assembly. Our results revealed a high-quality transcriptome with an N50 of 3,108 bp. Multivariate and differential expression analyses showed distinct tissue-specific signatures, Eye: Highly expressed genes were enriched in phagosome activity, oxidative stress response, and energy metabolism, suggesting a specialized maintenance program for this reduced visual organ. Ovary: Pathways related to DNA replication, arginine metabolism, and steroid biosynthesis were upregulated, likely supporting the unique demands of triploid parthenogenesis. Furthermore, WGCNA identified key co-expression modules and hub genes (e.g., GNB5, RNF114, and DDX20) associated with these tissues. Overall, our findings suggest that the specialized traits of I. braminus are driven by targeted, tissue-specific transcriptional programs rather than global genomic shifts.