RNAseq of different CD176-TRUCKs before and after co-culture with A549 tumor cells
CD176-TRUCKs with different transgenic payloads were generated from human primary CD8+ T cells of four donors. Bulk RNA was isolated before or after 48h co-cultures with CD176+ tumor cell line, A549. Details of experimental design can be found in the M&M section of the manuscript.
CD176-TRUCKs with different transgenic payloads were generated from human primary CD8+ T cells of four donors. Bulk RNA was isolated before or after 48h co-cultures with CD176+ tumor cell line, A549. Details of experimental design can be found in the M&M section of the manuscript.