Construction and evaluation of Aeromonas hydrophila vipB/flpL double-gene deletion mutant strain as a live attenuated vaccine in fish
Aquatic products occupy a pivotal position as premium protein sources within the global dietary nutrition framework. Aeromonas hydrophila is a human-animal commensal bacterium that seriously threatens the development of aquaculture and human health. The research aims to clarify the pathogenesis of A. hydrophila, and lay the foundation for developing live attenuated vaccines through the targeted modification flpL and vipB genes.