Mapping the impact of gut microbiota on brain and behaviour through the lens of GABA
This BioProject contains 16S rRNA gene amplicon sequencing data from faecal samples collected from healthy adult male participants enrolled in a cross-sectional study investigating the relationship between the gut microbiota and GABA-related phenotypes. The study integrates gut microbiota composition with serum GABA concentrations, proton magnetic resonance spectroscopy-derived brain GABA-plus measurements, functional MRI, and behavioural assessments related to GABAergic function. The sequencing data were generated to characterise gut microbial community composition and to investigate associations between microbial taxa, predicted microbial neuroactive metabolic pathways, and serum and central GABA-related measures. These data are intended to facilitate research into microbiota-gut-brain interactions in healthy humans.