Therapeutic Mechanisms of Strontium-90 Superficial Radiotherapy in Keloids: Integrating Senescence Induction and ECM Remodeling to Target Cell-Matrix Mechanics
The limited efficacy of current keloid therapies necessitates a deeper understanding of treatment mechanisms. This study investigates the therapeutic potential and underlying pharmacological actions of strontium-90 (Sr-90) superficial radiotherapy, proposing a novel dual-pathway antifibrotic framework