Whole-genome sequencing of 303 house mice (Mus musculus domesticus) to investigate invasion dynamics in Africa
This study investigates the colonization history of the house mouse (Mus musculus domesticus) in Africa, with a focus on reconstructing its invasion dynamics, origins, and interactions with other mouse species. We generated 303 low-coverage whole-genome sequences (lcWGS) of M. m. domesticus individuals sampled across diverse geographic regions. The dataset includes 216 samples from 13 populations across nine African countries, 73 samples from six populations in five European countries, and 14 samples from three populations in the species' putative native range in West Asia. These samples were either collected from the field or obtained from existing museum and scientific collections.  This project also included low-coverage whole-genome sequencing data for 17 wild Mus spretus individuals from Agadir, Morocco. These specimens were originally collected in 1985 and are preserved as museum samples at the Institut des Sciences de l'Évolution de Montpellier (ISEM). The dataset was produced to characterize genomic variation in M. spretus and to serve as a reference for comparative population genomic analyses, including investigations of interspecific introgression with the western house mouse (Mus musculus domesticus). These genome sequences provide a valuable resource for studying the evolutionary history, genetic diversity, and gene flow between closely related Mus species in Africa and Europe.
This study investigates the colonization history of the house mouse (Mus musculus domesticus) in Africa, with a focus on reconstructing its invasion dynamics, origins, and interactions with other mouse species. We generated 303 low-coverage whole-genome sequences (lcWGS) of M. m. domesticus individuals sampled across diverse geographic regions. The dataset includes 216 samples from 13 populations across nine African countries, 73 samples from six populations in five European countries, and 14 samples from three populations in the species' putative native range in West Asia. These samples were either collected from the field or obtained from existing museum and scientific collections.  This project also included low-coverage whole-genome sequencing data for 17 wild Mus spretus individuals from Agadir, Morocco. These specimens were originally collected in 1985 and are preserved as museum samples at the Institut des Sciences de l'Évolution de Montpellier (ISEM). The dataset was produced to characterize genomic variation in M. spretus and to serve as a reference for comparative population genomic analyses, including investigations of interspecific introgression with the western house mouse (Mus musculus domesticus). These genome sequences provide a valuable resource for studying the evolutionary history, genetic diversity, and gene flow between closely related Mus species in Africa and Europe.