RNA-seq profiling of orthotopic glioma tissues following low-intensity pulsed ultrasound treatment
This study investigated transcriptional changes induced by low-intensity pulsed ultrasound (LIPUS) in orthotopic murine glioma tissues. Tumor tissues from non-LIPUS control mice and LIPUS-treated mice were subjected to bulk RNA sequencing, with three biological replicates per group. The sequencing data were generated to characterize differential gene expression and pathway changes associated with cytosolic DNA sensing and cGAS-STING signaling following LIPUS treatment.