Low-Affinity Human/Mouse Cross-Reactive VHH Antibodies Against Transferrin Receptor 1 Enable Brain-Targeted Delivery
This study generated low-affinity human/mouse cross-reactive VHH antibodies against Transferrin Receptor 1 (TfR1) for brain targeting. To isolate efficiently, the author used NGS analysis to determine the specific clones that can bind both TfR1 antigens