HATUA project bacterial isolates from patients presenting with UTI in Tanzania
The HATUA (Holistic Approach to Unravel Antibacterial Resistance in East Africa) Consortium conducted multidisciplinary research in Uganda, Kenya, and Tanzania to unravel drivers of the antimicrobial resistance (AMR) using holist approach. In the year 2019-2020, a total of 7,583 patients were enrolled, of these, 35.0% were microbiologically confirmed to have urinary tract infections (UTIs). Enterobacterales and Staphylococcus spp. were predominantly identified and about 50% were MDR. These findings highlight a substantial contribution of multidrug-resistant (MDR) bacteria to UTIs in East Africa. The study underscores the need for the increased investment in laboratory capabilities and enhanced diagnostic accuracy to guide appropriate antibiotic use and effectively combat AMR. Isolates were sequenced and genotyped for AMR and virulence by the Fleming Fund SeqAfrica project, a UK Aid funded initiative to strengthen AMR surveillance in Africa.
The HATUA (Holistic Approach to Unravel Antibacterial Resistance in East Africa) Consortium conducted multidisciplinary research in Uganda, Kenya, and Tanzania to unravel drivers of the antimicrobial resistance (AMR) using holist approach. In the year 2019-2020, a total of 7,583 patients were enrolled, of these, 35.0% were microbiologically confirmed to have urinary tract infections (UTIs). Enterobacterales and Staphylococcus spp. were predominantly identified and about 50% were MDR. These findings highlight a substantial contribution of multidrug-resistant (MDR) bacteria to UTIs in East Africa. The study underscores the need for the increased investment in laboratory capabilities and enhanced diagnostic accuracy to guide appropriate antibiotic use and effectively combat AMR. Isolates were sequenced and genotyped for AMR and virulence by the Fleming Fund SeqAfrica project, a UK Aid funded initiative to strengthen AMR surveillance in Africa.
the seqafrica consortium