SARS-COV2 infections alters the upper respiratory tract microbiome, potentially contributing to disease severity through microbial dysbiosis and viral co-infections. In this study Nasal and oral swaps were collected from SARS-COV2 positive patients and Control (RT-PCR Negative) patients. Targeted viral enrichment and next generation Sequencing was performed. This study reveal dynamic alteration in the upper respiratory tract virome and microbiome associated with SARS-COV2 disease severity.
SARS-COV2 infections alters the upper respiratory tract microbiome, potentially contributing to disease severity through microbial dysbiosis and viral co-infections. In this study Nasal and oral swaps were collected from SARS-COV2 positive patients and Control (RT-PCR Negative) patients. Targeted viral enrichment and next generation Sequencing was performed. This study reveal dynamic alteration in the upper respiratory tract virome and microbiome associated with SARS-COV2 disease severity.
Indian Biological Data Centre