Genomic surveillance of malaria in West Africa (Phase 2)
This project addresses one of the main pillars of WHO's strategy for malaria elimination, namely to make surveillance a core intervention. Having established end-to-end implementation of genomic surveillance of malaria using Amplicon sequencing at the Medical Research Council Unit The Gambia (MRCG), this project builds regional networks aimed at developing capacity for managing multi-partner collaborations (with Senegal, Guinea, and Sierra Leone in the first instance) and provide training from sample collection through to the translation of genomic data into actionable knowledge in the different countries. We aim to integrate these genomic surveillance systems into the routine working practices of National Malaria Programs (NMPs) in countries that are part of the regional network and to provide a working example of how such systems could be deployed at other locations in Africa. We will translate genomic data into actionable knowledge, e.g. by providing early warning of newly emerging resistance and showing how specific interventions cause changes in the levels of resistance.
This project addresses one of the main pillars of WHO's strategy for malaria elimination, namely to make surveillance a core intervention. Having established end-to-end implementation of genomic surveillance of malaria using Amplicon sequencing at the Medical Research Council Unit The Gambia (MRCG), this project builds regional networks aimed at developing capacity for managing multi-partner collaborations (with Senegal, Guinea, and Sierra Leone in the first instance) and provide training from sample collection through to the translation of genomic data into actionable knowledge in the different countries. We aim to integrate these genomic surveillance systems into the routine working practices of National Malaria Programs (NMPs) in countries that are part of the regional network and to provide a working example of how such systems could be deployed at other locations in Africa. We will translate genomic data into actionable knowledge, e.g. by providing early warning of newly emerging resistance and showing how specific interventions cause changes in the levels of resistance.
Medical Research Council, The Gambia at LSHTM