RNA-seq of engineered T-REx-293 cell lines expressing standard or immunoproteasome
T-REx-293 cells expressing standard proteasome (b1, b2, b5), were transfected and cloned with plasmid allowing inducible expression of immunoproteasome (b1i, b2i, b5i) to investigate the impact of the proteasome isoform on the cell state and the MHC-I immunopeptidome.
T-REx-293 cells expressing standard proteasome (b1, b2, b5), were transfected and cloned with plasmid allowing inducible expression of immunoproteasome (b1i, b2i, b5i) to investigate the impact of the proteasome isoform on the cell state and the MHC-I immunopeptidome.
European Bioinformatics Institute