RNA-seq analysis of BV-2 microglia infected with Streptococcus pneumoniae
This study aimed to investigate transcriptomic changes associated with Streptococcus pneumoniae-induced inflammatory responses in BV-2 microglial cells. BV-2 cells were subjected to the indicated experimental treatments, and total RNA was extracted for high-throughput RNA sequencing. The dataset was generated to identify differentially expressed genes and signaling pathways involved in microglial activation, neuroinflammation, and NOD2/IRF5-related regulatory mechanisms during pneumococcal meningitis-related injury.
This study aimed to investigate transcriptomic changes associated with Streptococcus pneumoniae-induced inflammatory responses in BV-2 microglial cells. BV-2 cells were subjected to the indicated experimental treatments, and total RNA was extracted for high-throughput RNA sequencing. The dataset was generated to identify differentially expressed genes and signaling pathways involved in microglial activation, neuroinflammation, and NOD2/IRF5-related regulatory mechanisms during pneumococcal meningitis-related injury.
Qilu Hospital of Shandong University