gut microbiota; infants; nasopharyngeal microbiota; wheezing.
Impact:     • The microbiota of preterm neonates during the first week of life plays a pivotal role in determining the risk of respiratory diseases, such as wheezing, later in life.     • Clinical factors such as antibiotic use, delivery mode, and breastfeeding have a profound impact on microbiota composition, with specific genera such as Moraxella, Corynebacterium, and Bifidobacterium emerging as key biomarkers, making them important targets for interventions to promote long-term respiratory health in preterm infants. This is the first study that analyze this factors in the first week of life.     • To recognize microbial predictors of recurrent wheezing in preterm infants could allow to explore potential microbiota-modulating strategies to mitigate respiratory complications in this high-risk population
Impact:     • The microbiota of preterm neonates during the first week of life plays a pivotal role in determining the risk of respiratory diseases, such as wheezing, later in life.     • Clinical factors such as antibiotic use, delivery mode, and breastfeeding have a profound impact on microbiota composition, with specific genera such as Moraxella, Corynebacterium, and Bifidobacterium emerging as key biomarkers, making them important targets for interventions to promote long-term respiratory health in preterm infants. This is the first study that analyze this factors in the first week of life.     • To recognize microbial predictors of recurrent wheezing in preterm infants could allow to explore potential microbiota-modulating strategies to mitigate respiratory complications in this high-risk population
Institute of Agrochemistry and Food Technology - National Research Council (IATA-CSIC)