Time-course RNA-seq profiling of HCT116 cells treated with BRQ and JNK-IN-8
This study generated RNA-sequencing data from human colorectal cancer HCT116 cells treated with BRQ or JNK-IN-8 alone, or with the combination of both compounds, for 24 hours or 8 days. The objective was to characterize treatment-associated transcriptional responses and identify gene-expression programs altered by single-agent and combination treatment. These data may help elucidate molecular mechanisms underlying the interaction between BRQ and JNK inhibition and provide insight into potential therapeutic strategies for colorectal cancer.
BioProject