small RNAs sequencing on the placental EVs from preeclampsia and normotensive pregnancy
Placental extracellular vesicles (pEVs) are EVs secreted by trophoblast cells. As a messenger between the fetal and maternal, pEVs carry large number of various types of cargos. In order to better understanding the changes of the functions of pEVs during preeclampsia compared to normotensive pregnancy, in this study the small RNAs sequencing are conducted on the pEVs secreted by placentae from five early-onset preeclampsia, five late-onset preeclampsia and five normotensive pregnancies by ultracentrifuge assays via in vitro placental explants culture model.
Placental extracellular vesicles (pEVs) are EVs secreted by trophoblast cells. As a messenger between the fetal and maternal, pEVs carry large number of various types of cargos. In order to better understanding the changes of the functions of pEVs during preeclampsia compared to normotensive pregnancy, in this study the small RNAs sequencing are conducted on the pEVs secreted by placentae from five early-onset preeclampsia, five late-onset preeclampsia and five normotensive pregnancies by ultracentrifuge assays via in vitro placental explants culture model.
University of Auckland