scRNA-seq of control and IL-1RAcP knockout across Candida infection timecourse
Single-cell RNA sequencing was performed on murine oral tissue to characterise immune responses during Candida albicans infection. Control and IL-1RAcP knockout mice were analysed across a time course comprising naïve (uninfected), day 1, and day 2 post-infection samples. The dataset captures genotype-dependent differences in epithelial and immune cell populations and their transcriptional responses to infection. This study enables analysis of cell-type composition, activation states, and gene expression dynamics across infection and between genotypes.
Single-cell RNA sequencing was performed on murine oral tissue to characterise immune responses during Candida albicans infection. Control and IL-1RAcP knockout mice were analysed across a time course comprising naïve (uninfected), day 1, and day 2 post-infection samples. The dataset captures genotype-dependent differences in epithelial and immune cell populations and their transcriptional responses to infection. This study enables analysis of cell-type composition, activation states, and gene expression dynamics across infection and between genotypes.
European Bioinformatics Institute