scRNA-seq of organoids injected subcutaneously into C57BL/6 mice. Mice were treated with CD4 depletion antibody, CD8 depletion antibody or IgG control
Genetically engineered organoids with the genetic background VBPNA were injected subcutaneously into immunocompetent mice. The mice were treated with CD4 T cells depletion antibody, CD8 T cell depletion antibody or IgG control. The tumors sizes were measured weekly. The intent of the experiment was to determine if the distinct T cell population have an effect on tumor growth, cancer cell state and immune cells.
Genetically engineered organoids with the genetic background VBPNA were injected subcutaneously into immunocompetent mice. The mice were treated with CD4 T cells depletion antibody, CD8 T cell depletion antibody or IgG control. The tumors sizes were measured weekly. The intent of the experiment was to determine if the distinct T cell population have an effect on tumor growth, cancer cell state and immune cells.
European Bioinformatics Institute