RNA-seq of developmentally- and adult-labeled Tlx3-Cre-positive neurons in the mouse primary visual cortex
Tlx3 neurons are a class of intratelencephalic neurons in the neocortex. By using a Cre mouse line, we can label two, only partially overlapping, cell populations depending on the time of labelling. We call these developmentally and adult labelled cells based on the fact that cells are tagged by crossing a Cre line with a reporter mouse line (tdTomato) or by injecting a Cre-dependent AAV in adult mice We aim to understand transcriptomic differences between developmentally labelled and adult labelled Tlx3 neurons.
Tlx3 neurons are a class of intratelencephalic neurons in the neocortex. By using a Cre mouse line, we can label two, only partially overlapping, cell populations depending on the time of labelling. We call these developmentally and adult labelled cells based on the fact that cells are tagged by crossing a Cre line with a reporter mouse line (tdTomato) or by injecting a Cre-dependent AAV in adult mice We aim to understand transcriptomic differences between developmentally labelled and adult labelled Tlx3 neurons.
European Bioinformatics Institute