Streptococcus pyogenes genome assemblies of M1global M1T1 5448 and 5448AP
We report the circular genome sequence of the closely related S. pyogenes strains M1T1 5448 and M1T1AP. By using both long-read (MinION) and short-read (Illumina) sequencing, a 6001 bp gap in the M1T1 5448 RefSeq genome could be resolved. Furthermore, comparative synteny analysis identified a large chromosomal inversion between 5448 and 5448AP.
We report the circular genome sequence of the closely related S. pyogenes strains M1T1 5448 and M1T1AP. By using both long-read (MinION) and short-read (Illumina) sequencing, a 6001 bp gap in the M1T1 5448 RefSeq genome could be resolved. Furthermore, comparative synteny analysis identified a large chromosomal inversion between 5448 and 5448AP.
Max Planck Unit for the Science of Pathogens