RNA-seq of medullary bone of two high-yielding laying hen strains during the transition from immature pullet stage to the onset of laying
Medullary bone is deposited in the cavities of avian long bones and serves as a calcium reservoir for successful eggshell mineralization. Osteoblasts and osteoclasts located in medullary bone respond to endocrine changes, including high estrogen levels at sexual maturation, and represent important targets for improving mineral turnover in laying hens. In this experiment, we assessed the transcriptomic profile of medullary bone at 16, 17, 18, 20, 21, 22 and 23 weeks of age of Lohmann Brown (LB) and Lohmann Selected Leghorn (LSL) chickens.
Medullary bone is deposited in the cavities of avian long bones and serves as a calcium reservoir for successful eggshell mineralization. Osteoblasts and osteoclasts located in medullary bone respond to endocrine changes, including high estrogen levels at sexual maturation, and represent important targets for improving mineral turnover in laying hens. In this experiment, we assessed the transcriptomic profile of medullary bone at 16, 17, 18, 20, 21, 22 and 23 weeks of age of Lohmann Brown (LB) and Lohmann Selected Leghorn (LSL) chickens.
European Bioinformatics Institute