RNA-seq of engineered HEK-293-EBNA cell lines expressing standard, mixed, or immunoproteasome
HEK-293-EBNA cells were transfected and cloned to express either standard (b1, b2, b5), mixed (b1i, b2i, b5), or immunoproteasome (b1i, b2i, b5i) to investigate the impact of the proteasome isoform on the cell state and the MHC-I immunopeptidome.
HEK-293-EBNA cells were transfected and cloned to express either standard (b1, b2, b5), mixed (b1i, b2i, b5), or immunoproteasome (b1i, b2i, b5i) to investigate the impact of the proteasome isoform on the cell state and the MHC-I immunopeptidome.
European Bioinformatics Institute