Transcriptomic responses of Helicobacter pylori strains S7 and H390 to Bacteriocin F
This project investigates the transcriptional responses of Helicobacter pylori strains S7 (amoxicillin-susceptible) and H390 (amoxicillin-resistant) to synthetic Bacteriocin F. Log-phase cultures were exposed to 200 ug/mL Bacteriocin F for 8 h, with untreated cultures serving as strain-matched controls. RNA sequencing was performed using three biological replicates per condition to characterize strain-specific transcriptional changes involving bacterial adaptation and virulence-related processes.