Multi-tissue transcriptomic analysis of heat-stress adaptation in Leiqiong cattle compared with Holstein cattle
This project investigates breed-associated transcriptomic differences between Leiqiong cattle and Holstein cattle under a heat-stress context. Leiqiong cattle are a Chinese indigenous cattle breed adapted to hot and humid environments, whereas Holstein cattle were used as a heat-sensitive reference group. RNA-seq was performed on heart, liver, lung and longissimus dorsi muscle samples from eight Leiqiong cattle and nine Holstein cattle to identify genes and pathways associated with thermotolerance, immune regulation, lipid metabolism, oxidative stress and tissue-specific adaptation.