RNA sequencing of peripheral blood mononuclear cells from patients with intracranial aneurysm
This project profiles the transcriptome and RNA editing landscape of peripheral blood mononuclear cells (PBMCs) from 32 patients with intracranial aneurysm. Total RNA was extracted from PBMCs, poly(A)-selected mRNA libraries were prepared using the NEBNext Ultra II RNA Library Prep Kit for Illumina, and libraries were sequenced on an Illumina NovaSeq 6000 platform with paired-end 150 bp reads. The data support investigation of RNA editing and gene-expression alterations associated with immune-inflammatory responses and vascular function in intracranial aneurysm.