Sex-biased transcriptome profiling in embryonic mouse cortex under Pax6 haploinsufficiency
This study aims to characterize sex-biased transcriptomic profiles in the embryonic cortex of Pax6 mutant mice. Total RNA was extracted from the telencephalon of wild-type (WT), heterozygous (Sey/+), and homozygous (Sey/Sey) embryos from both males and females at embryonic day 14.5 (E14.5). Bulk RNA sequencing was performed to compare gene expression patterns between sexes and genotypes. The dataset provides a resource for investigating sex-dependent transcriptional regulation during cortical development under Pax6 haploinsufficiency. Data were generated at the Department of Developmental Neuroscience, Graduate School of Medicine, Tohoku University, Japan.
This study aims to characterize sex-biased transcriptomic profiles in the embryonic cortex of Pax6 mutant mice. Total RNA was extracted from the telencephalon of wild-type (WT), heterozygous (Sey/+), and homozygous (Sey/Sey) embryos from both males and females at embryonic day 14.5 (E14.5). Bulk RNA sequencing was performed to compare gene expression patterns between sexes and genotypes. The dataset provides a resource for investigating sex-dependent transcriptional regulation during cortical development under Pax6 haploinsufficiency. Data were generated at the Department of Developmental Neuroscience, Graduate School of Medicine, Tohoku University, Japan.