Coordinated P450-UGT detoxification shapes host-range divergence in polyphagous and oligophagous Helicoverpa species
Plants and herbivorous insects are engaged in a continuous evolutionary arms race driven by chemical defences and counter-defences. How insects integrate distinct detoxification systems to cope with diverse plant secondary metabolites and how such mechanisms contribute to host-range divergence remain poorly understood. This transcriptome dataset was generated to investigate the molecular mechanisms underlying plant secondary metabolite detoxification in Helicoverpa, with a particular focus on the coordinated roles of cytochrome P450s and UDP-glycosyltransferases (UGTs) in furanocoumarin tolerance.