RNA-seq of human dental follicle stem cells under aging and IGFBP5 overexpression
This project provides bulk RNA sequencing data from primary human dental follicle stem cells (hDFSCs) under four experimental conditions: young control (YC), H2O2-induced oxidative stress senescence (OSS), replicative senescence (RS), and IGFBP5 lentiviral overexpression (IGFBP5-OE) compared to blank vehicle. These data were generated to elucidate transcriptomic alterations associated with stem cell aging and to investigate the regulatory role of IGFBP5 in periodontal tissue regeneration.