Whole-genome resequencing of Chinese mitten crab (Eriocheir sinensis) for MIP panel validation
The Chinese mitten crab (Eriocheir sinensis) is one of China's most valuable aquaculture species, yet insufficient germplasm management and uncontrolled stocking have driven its genetic admixture and degradation, creating an urgent need for efficient genotyping tools to support conservation and selective breeding. Here we developed a molecular inversion probe (MIP) panel for E. sinensis, a hybridization-based enrichment strategy widely used in clinical diagnostics but not yet applied in aquaculture. The whole-genome resequencing data provided here were used to generate a reference VCF, enabling the benchmarking and validation of MIP-generated genotypes.