Long-read transcriptomics reveals viral load-dependent isoform switching in MERS-CoV-infected human lung cells
Coronaviruses extensively reprogram host gene expression, yet isoform-level regulation remains poorly defined. Here we combine time-resolved long-read RNA sequencing with proteomics to characterise host transcriptome dynamics during MERS-CoV infection.
Coronaviruses extensively reprogram host gene expression, yet isoform-level regulation remains poorly defined. Here we combine time-resolved long-read RNA sequencing with proteomics to characterise host transcriptome dynamics during MERS-CoV infection.