snRNA data of Brain section from Parkinson Mouse Model based on inducible expression of human a-syn constructs including conditions with pharmacological CDC42 inhibition
Using 6-months, 16-months, and 24-months old mice of a inducible expression of human a-syn constructs based Parkinson mouse model, we produced a single nucleus RNA dataset by cutting 0mm Bregma to -5mm Bregma. The Chromium 3' Single Cell Library Kit (10x Genomics) was used and Sequencing was performed on a NovaSeq 6000. Conditions are included that got pharmacological inhibition of Cdc42 activity.  Processed files can be found on Zenodo: 10.5281/zenodo.21621060
Using 6-months, 16-months, and 24-months old mice of a inducible expression of human a-syn constructs based Parkinson mouse model, we produced a single nucleus RNA dataset by cutting 0mm Bregma to -5mm Bregma. The Chromium 3' Single Cell Library Kit (10x Genomics) was used and Sequencing was performed on a NovaSeq 6000. Conditions are included that got pharmacological inhibition of Cdc42 activity.  Processed files can be found on Zenodo: 10.5281/zenodo.21621060