RNA-seq data of Fusarium graminearum in response to a structure-based antifungal compound targeting FgUbiH
We performed a transcriptomic analysis to evaluate the response of Fusarium graminearum to a candidate antifungal compound predicted by molecular docking targeting the FgUbiH protein. The wild-type (PH-1, W) and the FgUbiH-targeted strain (U) were grown in CM liquid medium for 48 hours and then exposed to the compound for 6 hours, with corresponding treated samples labeled as WR and UR. Physiological and biochemical assays were conducted in parallel. The transcriptome data will help to elucidate the regulatory networks underlying the compound's antifungal effects and its interaction with the FgUbiH target.