Dose response effects of microencapsulated Lacticaseibacillus rhamnosus GG in a yogurt drink on gut microbiome modulation in healthy adults: a randomized, double-blind crossover trial
Probiotic efficacy is hypothesized to depend on reliable intestinal exposure, yet clinical evidence linking delivery engineering to measurable microbiome responses in humans remains limited. We evaluated dose response effects of microencapsulated Lacticaseibacil-lus rhamnosus GG on gastrointestinal tolerance and gut microbiome composition in 26 healthy adults in a randomized, double-blind, two period crossover trial.