Targeted editing of host susceptibility factors to engineer multiple disease resistance in tomato
This study focuses on the targeted editing of host susceptibility factors in tomato (Solanum lycopersicum) to develop broad-spectrum and multiple disease resistance. The project aims to identify and functionally characterize host genes that contribute to susceptibility to major tomato pathogens and evaluate their potential as targets for genome editing. Targeted modification of selected susceptibility factors will be investigated for its ability to enhance resistance against multiple diseases while maintaining desirable plant growth and agronomic traits. The generated genomic and molecular data will support the development of disease-resistant tomato lines and provide insights into host-pathogen interactions and plant immune responses.