Entamoeba histolytica Genome sequencing and assembly
Entamoeba histolytica, the causative agent of amoebic dysentery, is an important pathogenic eukaryote. Although its genome is relatively small (20-40 Mb), obtaining high-quality assemblies has been challenging due to extensive repetitive regions, tRNA gene arrays, and frequent aneuploidy. Here, we used PacBio Hi-Fi sequencing together with Hi-C reads to assemble the genomes of E. histolytica.