Genomic diversity and phenotypic heterogeneity of Klebsiella pneumoniae isolates causing bloodstream infection in an infectious disease hospital in Ho Chi Minh City, Vietnam
A high proportion of bloodstream infections (BSIs) caused by K. pneumoniae in Vietnam, with the epidemiology, population structures and transmission dynamics of hvKp being well described. However, there is little known about how virulence-associated traits contribute to increased pathogenicity and attributable genetic determinants. In this study, a subset of clinical isolates was used to investigate the genomic structure and population of K. pneumoniae BSI isolates and characterise specific phenotypic features of hvKp associated with clinical manifestations
A high proportion of bloodstream infections (BSIs) caused by K. pneumoniae in Vietnam, with the epidemiology, population structures and transmission dynamics of hvKp being well described. However, there is little known about how virulence-associated traits contribute to increased pathogenicity and attributable genetic determinants. In this study, a subset of clinical isolates was used to investigate the genomic structure and population of K. pneumoniae BSI isolates and characterise specific phenotypic features of hvKp associated with clinical manifestations