16S rRNA gene sequencing of gut microbiota from DSS-induced colitis mice treated with Exocarpium Citri Grandis-derived extracellular vesicle-like particles (ECG-EVLPs)
Ulcerative colitis (UC) is a chronic inflammatory bowel disease closely associated with gut microbiota dysbiosis. Exocarpium Citri Grandis-derived extracellular vesicle-like particles (ECG-EVLPs) have been shown to alleviate DSS-induced colitis in mice. To explore the underlying mechanisms, we performed 16S rRNA gene sequencing (V3-V4 region) of fecal samples from C57BL/6 mice across three groups: normal control, DSS-induced colitis model, and ECG-EVLPs-treated group. The sequencing data were used to assess alpha and beta diversity, microbial community composition, and differentially abundant taxa among groups. This dataset provides insights into how ECG-EVLPs modulate gut microbial ecology and contribute to colitis amelioration.