Fetal Sex Shapes the Immune Landscape at the Maternal Fetal Interface During Early Human Pregnancy
This project aims to profile the transcriptomic landscape of early human placental development during the first trimester of pregnancy. Placental tissues were collected from elective terminations between 6 and 8 weeks of gestation. Bulk RNA sequencing was performed on chorionic villus samples to capture early trophoblast and immune cell transcriptional programs. The resulting data provide a high-resolution view of gene expression dynamics during the critical window of placental implantation and early fetal maternal interface formation. These data can serve as a reference for developmental studies and comparative analyses in placental biology.