Paired pre-treatment and virological failure sequencing of hepatitis C virus subtype 6f from a decentralised elimination programme, Phetchabun, Thailand
NS5A and NS5B amplicon sequencing of paired serum specimens collected before sofosbuvir/velpatasvir therapy and at virological failure, from patients enrolled in a province-wide hepatitis C test-and-treat programme. Reads were used to adjudicate consensus-level resistance calls at read level and to characterise within-host diversity across therapy.