Metagenomic profiling and whole-genome sequencing of clinical samples from 853 patients with tuberculosis-like symptoms
This project aims to characterize the microbial diversity in patients exhibiting tuberculosis (TB) symptoms using whole-genome sequencing (WGS). We sequenced clinical samples collected from 853 symptomatic patients to identify the causative agents of their symptoms. Genomic analysis revealed the presence of Mycobacterium tuberculosis, Non-Tuberculous Mycobacteria (NTM), and other bacterial species. This dataset provides valuable genomic resources to understand the distribution of TB, NTM, and potential co-infections in TB-suspected cohorts, ultimately contributing to improved differential diagnosis and epidemiological surveillance.