RNA-seq profiling of A549 xenograft tumors following intratumoral administration of tuberculous pleural effusion-derived exosomes
A549 lung adenocarcinoma cells were xenografted into BALB/c nude mice. After tumor establishment, mice were treated with either PBS (control) or tuberculous pleural effusion (TPE)-derived exosomes by intratumoral injection. Tumors were harvested on day 21, and RNA-sequencing was performed on RNA extracts to investigate gene expression changes associated with TPE-derived exosome treatment.
A549 lung adenocarcinoma cells were xenografted into BALB/c nude mice. After tumor establishment, mice were treated with either PBS (control) or tuberculous pleural effusion (TPE)-derived exosomes by intratumoral injection. Tumors were harvested on day 21, and RNA-sequencing was performed on RNA extracts to investigate gene expression changes associated with TPE-derived exosome treatment.